Detailed information of TA system TA100717

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 579698..579878
• Replicon: chromosome
• Accession: NZ_CP028165
• Organism: Staphylococcus aureus strain CFSAN064037

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: C9J78_RS02775
• Protein ID: WP_001801861.1
• Coordinates: 579698..579793 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	579821..579878 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C9J78_RS02735	574765..575337	+	573	WP_000414229.1	hypothetical protein	-
C9J78_RS02740	575713..576549	+	837	WP_000190484.1	ABC transporter ATP-binding protein	-
C9J78_RS02750	577356..577541	-	186	WP_000809858.1	hypothetical protein	-
C9J78_RS02755	577543..577719	-	177	WP_000375476.1	hypothetical protein	-
C9J78_RS02760	577730..578113	-	384	WP_000070811.1	hypothetical protein	-
C9J78_RS02765	578800..579246	-	447	WP_000747809.1	DUF1433 domain-containing protein	-
C9J78_RS02775	579698..579793	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	579821..579878	-	58	-	-	Antitoxin
C9J78_RS02780	579916..580017	+	102	WP_001791232.1	hypothetical protein	-
C9J78_RS02785	580055..580171	-	117	Protein_533	transposase	-
C9J78_RS02790	580680..584792	-	4113	WP_107240618.1	ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	576537..649805	73268

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T100717 WP_001801861.1 NZ_CP028165:579698-579793 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T100717 NZ_CP028165:579698-579793 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT100717 NZ_CP028165:c579878-579821 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin