Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1108692..1108955 Replicon chromosome
Accession NZ_CP028163
Organism Staphylococcus aureus strain CFSAN064038

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag C9J77_RS05645 Protein ID WP_001802298.1
Coordinates 1108692..1108796 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1108791..1108955 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J77_RS05610 1104591..1105199 + 609 WP_000101714.1 TIR domain-containing protein -
C9J77_RS05615 1105489..1106271 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
C9J77_RS05620 1106339..1107196 + 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
C9J77_RS05625 1107326..1107418 - 93 WP_000220902.1 hypothetical protein -
C9J77_RS05630 1107854..1108012 - 159 WP_001792784.1 hypothetical protein -
C9J77_RS05645 1108692..1108796 + 105 WP_001802298.1 hypothetical protein Toxin
- 1108791..1108955 - 165 - - Antitoxin
C9J77_RS05650 1109294..1110385 - 1092 WP_000495673.1 hypothetical protein -
C9J77_RS05655 1110651..1111631 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
C9J77_RS05660 1111633..1111953 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
C9J77_RS05665 1112105..1112770 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T100705 WP_001802298.1 NZ_CP028163:1108692-1108796 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T100705 NZ_CP028163:1108692-1108796 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT100705 NZ_CP028163:c1108955-1108791 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References