Detailed information of TA system TA100368

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 1210755..1210902
• Replicon: chromosome
• Accession: NZ_CP027846
• Organism: Staphylococcus kloosii strain ATCC 43959

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: C7J89_RS05915
• Protein ID: WP_106884395.1
• Coordinates: 1210755..1210850 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1210873..1210902 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7J89_RS05895	1206249..1207628	-	1380	WP_103295285.1	aldehyde dehydrogenase	-
C7J89_RS05900	1207735..1208661	-	927	WP_103295284.1	manganese-dependent inorganic pyrophosphatase	-
C7J89_RS05905	1208709..1209269	-	561	WP_103295283.1	cysteine hydrolase family protein	-
C7J89_RS05910	1209411..1210493	+	1083	WP_103295282.1	right-handed parallel beta-helix repeat-containing protein	-
C7J89_RS05915	1210755..1210850	+	96	WP_106884395.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1210873..1210902	+	30	-	-	Antitoxin
C7J89_RS05920	1211049..1211852	-	804	WP_103295281.1	prephenate dehydratase	-
C7J89_RS05925	1211884..1212948	-	1065	WP_103295280.1	nitric oxide synthase oxygenase	-
C7J89_RS05930	1213128..1214597	+	1470	WP_103295279.1	nicotinate phosphoribosyltransferase	-
C7J89_RS05935	1214590..1215411	+	822	WP_103295278.1	ammonia-dependent NAD(+) synthetase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3669.38 Da
• Isoelectric Point: 8.0615

>T100368 WP_106884395.1 NZ_CP027846:1210755-1210850 [Staphylococcus kloosii]
MLDFLVHNMTLVINGCIIALFAHWLRNRNDK

Nucleotide

• Length: 96 bp

>T100368 NZ_CP027846:1210755-1210850 [Staphylococcus kloosii]
ATGTTGGATTTCCTTGTTCACAATATGACTTTAGTCATCAATGGTTGTATTATTGCGTTATTTGCGCATTGGCTGCGTAA
TCGCAATGACAAATAG

Antitoxin

Nucleotide

• Length: 30 bp

>AT100368 NZ_CP027846:1210873-1210902 [Staphylococcus kloosii]
AATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin