Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 517195..517901 Replicon chromosome
Accession NZ_CP027792
Organism Pulveribacter suum strain SC2-7

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag C7H73_RS02295 Protein ID WP_106845181.1
Coordinates 517195..517497 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag C7H73_RS02300 Protein ID WP_106845182.1
Coordinates 517500..517901 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C7H73_RS02280 512552..513754 + 1203 WP_106845178.1 ABC transporter substrate-binding protein -
C7H73_RS02285 513754..515649 + 1896 WP_106845179.1 ABC transporter permease -
C7H73_RS02290 515646..517154 + 1509 WP_106845180.1 ATP-binding cassette domain-containing protein -
C7H73_RS02295 517195..517497 + 303 WP_106845181.1 type II toxin-antitoxin system MqsR family toxin Toxin
C7H73_RS02300 517500..517901 + 402 WP_106845182.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
C7H73_RS02305 517942..519657 - 1716 WP_106845183.1 MCP four helix bundle domain-containing protein -
C7H73_RS02310 519858..521399 - 1542 WP_106845184.1 YifB family Mg chelatase-like AAA ATPase -
C7H73_RS02315 521550..521888 + 339 WP_106845185.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10998.71 Da        Isoelectric Point: 6.4490

>T100329 WP_106845181.1 NZ_CP027792:517195-517497 [Pulveribacter suum]
MEKGTPHCRLATVKALVQDGRVRATASAYDGVWELGIEDLAGMCAVVLALQPADFYKSMTTHADPRIWQDVYRPRSAAGS
SVYLKLTVIDDVLIVSFKEL

Download         Length: 303 bp

>T100329 NZ_CP027792:517195-517497 [Pulveribacter suum]
CTGGAGAAGGGCACGCCGCATTGCAGGCTGGCCACGGTGAAGGCGCTGGTGCAGGACGGCCGGGTGCGCGCGACCGCCAG
TGCCTACGACGGCGTCTGGGAACTGGGCATTGAAGACCTGGCGGGCATGTGCGCGGTGGTGCTGGCGCTGCAACCTGCAG
ACTTCTACAAGAGCATGACGACCCACGCCGACCCCCGCATCTGGCAGGACGTGTACCGCCCCCGTAGCGCAGCCGGCAGC
AGCGTGTACCTCAAGCTCACCGTCATCGACGATGTGCTGATCGTTTCGTTCAAGGAGCTGTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14648.80 Da        Isoelectric Point: 8.1207

>AT100329 WP_106845182.1 NZ_CP027792:517500-517901 [Pulveribacter suum]
MKCPVCGAAELVRETRDLPYTYKGESTTIVAVAGDWCPVCAEVVLERDSGDRYAQSTAAFRRQVNAAAIDPGYIAQVRKK
LSLDQRQAAELFGGGVNAFSRYETGKTRPPLALVQLLRLLDRHPHLLQEMTAV

Download         Length: 402 bp

>AT100329 NZ_CP027792:517500-517901 [Pulveribacter suum]
ATGAAATGCCCTGTCTGCGGTGCCGCCGAACTGGTCCGCGAAACGCGAGACCTGCCCTACACCTACAAGGGTGAGAGCAC
CACCATCGTCGCCGTGGCAGGCGACTGGTGCCCGGTCTGCGCCGAGGTGGTGCTGGAGCGCGACAGCGGCGACCGTTACG
CCCAAAGCACGGCAGCGTTTCGTCGCCAGGTCAACGCAGCCGCCATCGACCCCGGCTACATCGCTCAGGTGCGCAAGAAG
CTATCTCTGGACCAGCGCCAGGCGGCCGAGCTGTTCGGCGGCGGGGTGAATGCCTTCTCGCGCTACGAGACCGGCAAGAC
GCGCCCGCCGCTGGCGCTGGTGCAGCTGCTGCGGCTGCTGGACCGCCACCCGCACCTGTTGCAGGAGATGACGGCAGTCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References