Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3931906..3932560 Replicon chromosome
Accession NZ_CP027756
Organism Pseudomonas synxantha strain R6-28-08

Toxin (Protein)


Gene name higB Uniprot ID A0A0R2YXS2
Locus tag C4K01_RS18145 Protein ID WP_057024311.1
Coordinates 3931906..3932256 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0W0N117
Locus tag C4K01_RS18150 Protein ID WP_014718915.1
Coordinates 3932246..3932560 (+) Length 105 a.a.

Genomic Context


C4K01_RS18135C4K01_RS18140C4K01_RS18145C4K01_RS18150C4K01_RS18165C4K01_RS18180C4K01_RS18155C4K01_RS18160C4K01_RS18170C4K01_RS18175C4K01_RS18185
Location: 3928665..3930197 (1533 bp)
Type: Others
Protein ID: WP_057024312.1
Location: 3930205..3931668 (1464 bp)
Type: Others
Protein ID: WP_003192122.1
Location: 3931906..3932256 (351 bp)
Type: Toxin
Protein ID: WP_057024311.1
Location: 3932246..3932560 (315 bp)
Type: Antitoxin
Protein ID: WP_014718915.1
Location: 3934451..3934687 (237 bp)
Type: Others
Protein ID: WP_005789137.1
Location: 3935231..3935752 (522 bp)
Type: Others
Protein ID: WP_057024308.1
Location: 3932621..3933373 (753 bp)
Type: Others
Protein ID: WP_057024310.1
Location: 3933499..3934332 (834 bp)
Type: Others
Protein ID: WP_057024309.1
Location: 3934718..3934924 (207 bp)
Type: Others
Protein ID: WP_046068647.1
Location: 3934937..3935116 (180 bp)
Type: Others
Protein ID: WP_046068648.1
Location: 3935760..3936890 (1131 bp)
Type: Others
Protein ID: WP_057024307.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
C4K01_RS181353928665..3930197+1533WP_057024312.1NADH-quinone oxidoreductase subunit M-
C4K01_RS181403930205..3931668+1464WP_003192122.1NADH-quinone oxidoreductase subunit NuoN-
C4K01_RS181453931906..3932256+351WP_057024311.1hypothetical proteinToxin
C4K01_RS181503932246..3932560+315WP_014718915.1XRE family transcriptional regulatorAntitoxin
C4K01_RS181553932621..3933373-753WP_057024310.1outer membrane beta-barrel protein-
C4K01_RS181603933499..3934332-834WP_057024309.1arylamine N-acetyltransferase-
C4K01_RS181653934451..3934687+237WP_005789137.1hypothetical protein-
C4K01_RS181703934718..3934924-207WP_046068647.1hypothetical protein-
C4K01_RS181753934937..3935116-180WP_046068648.1hypothetical protein-
C4K01_RS181803935231..3935752+522WP_057024308.1DUF3087 domain-containing protein-
C4K01_RS181853935760..3936890-1131WP_057024307.1MFS transporter-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 117 a.a.        Molecular weight: 13758.68 Da        Isoelectric Point: 9.7334

>T100216 WP_057024311.1 NZ_CP027756:3931906-3932256 [Pseudomonas synxantha]
MDALFIELPAFERHRKDYLSDELFQGFQQELMKTPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLTPHHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

>T100216 NZ_CP027756:3931906-3932256 [Pseudomonas synxantha]
ATGGATGCTCTATTTATCGAACTGCCGGCATTCGAGCGGCATCGCAAGGACTATCTCAGTGACGAGCTTTTCCAGGGTTT
TCAACAGGAGTTAATGAAAACCCCCGAAGCAGGAGATGTGATCGAAGGAACGGGCGGGTTGAGAAAGGTTCGCTTCGTTG
ATGAACGGCGAAACAAAGGCAAGCGTGGTGGCCTGCGAGTCATTTACTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCTTGTACGGCAAGCACGAACAGAGCGACCTGACACCCCACCACAAGAAAGCTCTTAAACACATGCTGGACAGGGA
AATCAAAGCGAGAACACATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11755.58 Da        Isoelectric Point: 10.6525

>AT100216 WP_014718915.1 NZ_CP027756:3932246-3932560 [Pseudomonas synxantha]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT100216 NZ_CP027756:3932246-3932560 [Pseudomonas synxantha]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGCTTCGACGCCCTGGCCGATGAGCGCCAGGGTAAAATCACCCTGCG
CAACCACAAGGTCCACCTCAACAAGCTGGCGCCGCTCACCGCTGATGAGGTGATCGCCGTGCGCCAGCAACTCAACCTTT
CCCGGTCGGTATTCGCCATGTACCTGCGTACCAACACCCGCACCCTGGAGAACTGGGAACAAGGCCGGGCCAAGCCCAAC
GCCCAGGCCGTCACCCTGATCCGTCTGGTAGCGCGTTTTCCTGAAACCGTGGCTCAACTTGCCGCATTGGGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A0R2YXS2


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0W0N117

References