Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3850095..3850749 Replicon chromosome
Accession NZ_CP027755
Organism Pseudomonas synxantha strain 2-79

Toxin (Protein)


Gene name higB Uniprot ID A0A0D0TQT9
Locus tag C4K02_RS17350 Protein ID WP_043046578.1
Coordinates 3850095..3850445 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0D0SQR0
Locus tag C4K02_RS17355 Protein ID WP_043046577.1
Coordinates 3850435..3850749 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K02_RS17340 3846854..3848386 + 1533 WP_043046580.1 NADH-quinone oxidoreductase subunit M -
C4K02_RS17345 3848394..3849857 + 1464 WP_043046579.1 NADH-quinone oxidoreductase subunit NuoN -
C4K02_RS17350 3850095..3850445 + 351 WP_043046578.1 toxin Toxin
C4K02_RS17355 3850435..3850749 + 315 WP_043046577.1 XRE family transcriptional regulator Antitoxin
C4K02_RS17360 3850809..3851561 - 753 WP_043046575.1 outer membrane beta-barrel protein -
C4K02_RS17365 3851687..3852520 - 834 WP_043046573.1 arylamine N-acetyltransferase -
C4K02_RS17370 3852639..3852875 + 237 WP_005789137.1 hypothetical protein -
C4K02_RS17375 3852906..3853112 - 207 WP_043046571.1 hypothetical protein -
C4K02_RS17380 3853125..3853304 - 180 WP_043046570.1 hypothetical protein -
C4K02_RS17385 3853419..3853940 + 522 WP_043046569.1 DUF3087 domain-containing protein -
C4K02_RS17390 3853948..3855078 - 1131 WP_043046568.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13785.70 Da        Isoelectric Point: 9.7334

>T100206 WP_043046578.1 NZ_CP027755:3850095-3850445 [Pseudomonas synxantha]
MDALFIELPAFERHRKDYLSEELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLTPHHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

>T100206 NZ_CP027755:3850095-3850445 [Pseudomonas synxantha]
ATGGATGCTCTATTTATCGAACTGCCGGCATTCGAGCGGCATCGCAAGGACTATCTGAGTGAGGAGCTTTTCCAGGGTTT
TCAACAGGAGTTAATGAAAAACCCCGAAGCAGGAGATGTGATCGAAGGAACGGGCGGGCTGAGAAAGGTTCGCTTCGTTG
ATGAACGGCGAAACAAAGGCAAGCGTGGTGGCCTGCGAGTCATTTACTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCTTGTACGGCAAGCACGAACAGAGCGACCTGACACCCCACCACAAGAAAGCGCTTAAACACATGCTGGACAGGGA
AATCAAAGCGAGAACACATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11741.51 Da        Isoelectric Point: 10.4449

>AT100206 WP_043046577.1 NZ_CP027755:3850435-3850749 [Pseudomonas synxantha]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNNLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT100206 NZ_CP027755:3850435-3850749 [Pseudomonas synxantha]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGCTTCGACGCCCTAGCCGATGAGCGCCAGGGTAAAATCACCCTGCG
CAACCACAAGGTCCACCTCAACAATCTGGCGCCGCTCACCGCTGATGAGGTGATCGCCGTGCGCCAGCAACTCAACCTTT
CCCGGTCGGTATTCGCCATGTACCTGCGTACCAACACCCGCACCCTGGAGAACTGGGAACAAGGCAGGGCCAAGCCCAAC
GCCCAGGCCGTCACCCTGATCCGTCTGGTAGCGCGTTTTCCTGAAACCGTGGCGCAACTTGCCGCATTGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D0TQT9

Antitoxin

Source ID Structure
AlphaFold DB A0A0D0SQR0

References