Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4410842..4411496 Replicon chromosome
Accession NZ_CP027752
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR38

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4K05_RS19805 Protein ID WP_096376050.1
Coordinates 4410842..4411192 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4K05_RS19810 Protein ID WP_009049793.1
Coordinates 4411182..4411496 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K05_RS19795 4407592..4409124 + 1533 WP_124301865.1 NADH-quinone oxidoreductase subunit M -
C4K05_RS19800 4409132..4410595 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
C4K05_RS19805 4410842..4411192 + 351 WP_096376050.1 toxin Toxin
C4K05_RS19810 4411182..4411496 + 315 WP_009049793.1 transcriptional regulator Antitoxin
C4K05_RS19815 4411663..4413405 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
C4K05_RS19825 4413569..4413841 - 273 WP_009049795.1 DUF2160 domain-containing protein -
C4K05_RS19830 4413852..4414652 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
C4K05_RS19835 4414664..4415530 - 867 WP_016701903.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13803.77 Da        Isoelectric Point: 9.4187

>T100187 WP_096376050.1 NZ_CP027752:4410842-4411192 [Pseudomonas chlororaphis subsp. aureofaciens]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T100187 NZ_CP027752:4410842-4411192 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAGTTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAACAGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAATTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTCAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11917.85 Da        Isoelectric Point: 10.6052

>AT100187 WP_009049793.1 NZ_CP027752:4411182-4411496 [Pseudomonas chlororaphis subsp. aureofaciens]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT100187 NZ_CP027752:4411182-4411496 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCTACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCTGAAGAAGTGCTGGCCGTACGCGAGCAGTTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACTACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCATTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References