Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4363130..4363784 Replicon chromosome
Accession NZ_CP027751
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzTR18

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4K06_RS19785 Protein ID WP_096376050.1
Coordinates 4363130..4363480 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4K06_RS19790 Protein ID WP_009049793.1
Coordinates 4363470..4363784 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K06_RS19775 4359880..4361412 + 1533 WP_124301865.1 NADH-quinone oxidoreductase subunit M -
C4K06_RS19780 4361420..4362883 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
C4K06_RS19785 4363130..4363480 + 351 WP_096376050.1 toxin Toxin
C4K06_RS19790 4363470..4363784 + 315 WP_009049793.1 transcriptional regulator Antitoxin
C4K06_RS19795 4363951..4365693 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
C4K06_RS19805 4365857..4366129 - 273 WP_009049795.1 DUF2160 domain-containing protein -
C4K06_RS19810 4366140..4366940 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
C4K06_RS19815 4366952..4367818 - 867 WP_016701903.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13803.77 Da        Isoelectric Point: 9.4187

>T100178 WP_096376050.1 NZ_CP027751:4363130-4363480 [Pseudomonas chlororaphis subsp. aureofaciens]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T100178 NZ_CP027751:4363130-4363480 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAGTTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAACAGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAATTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTCAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11917.85 Da        Isoelectric Point: 10.6052

>AT100178 WP_009049793.1 NZ_CP027751:4363470-4363784 [Pseudomonas chlororaphis subsp. aureofaciens]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT100178 NZ_CP027751:4363470-4363784 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCTACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCTGAAGAAGTGCTGGCCGTACGCGAGCAGTTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACTACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCATTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References