Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4346681..4347335 Replicon chromosome
Accession NZ_CP027750
Organism Pseudomonas chlororaphis subsp. aureofaciens strain ChPhzS24

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4K07_RS19475 Protein ID WP_096376050.1
Coordinates 4346681..4347031 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4K07_RS19480 Protein ID WP_009049793.1
Coordinates 4347021..4347335 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4K07_RS19465 4343431..4344963 + 1533 WP_124301865.1 NADH-quinone oxidoreductase subunit M -
C4K07_RS19470 4344971..4346434 + 1464 WP_009049791.1 NADH-quinone oxidoreductase subunit NuoN -
C4K07_RS19475 4346681..4347031 + 351 WP_096376050.1 toxin Toxin
C4K07_RS19480 4347021..4347335 + 315 WP_009049793.1 transcriptional regulator Antitoxin
C4K07_RS19485 4347502..4349244 - 1743 WP_023964376.1 ABC transporter substrate-binding protein -
C4K07_RS19495 4349408..4349680 - 273 WP_009049795.1 DUF2160 domain-containing protein -
C4K07_RS19500 4349691..4350491 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
C4K07_RS19505 4350503..4351369 - 867 WP_016701903.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13803.77 Da        Isoelectric Point: 9.4187

>T100171 WP_096376050.1 NZ_CP027750:4346681-4347031 [Pseudomonas chlororaphis subsp. aureofaciens]
MDALFIELPPFQRHRQDYLDDELFRSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQNDLTPHQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

>T100171 NZ_CP027750:4346681-4347031 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGGACGCACTTTTTATTGAGCTGCCCCCGTTCCAACGCCATCGACAGGACTACCTGGACGACGAGCTTTTTCGTAGCTT
GCAGCTTGAGTTGCTGAAAGCCCCCGAAGCCGGAGATCTCATCGAGGGAACAGGTGGCTTGCGCAAGATCCGCTTTGTCG
ATGAGCGACGGCACAAGGGCAAACGCGGCGGGATCCGGGTGATTTATTACTGGTGGTCCGGAGGCGCCCAATTCTGGCTC
TTCACCCTTTACGCAAAGAACGAGCAGAACGACCTGACACCCCATCAGAAAAAACTGCTCAAGCAACTGCTCAACAGAGA
AGTCGAGGCGAGAACCCATCATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11917.85 Da        Isoelectric Point: 10.6052

>AT100171 WP_009049793.1 NZ_CP027750:4347021-4347335 [Pseudomonas chlororaphis subsp. aureofaciens]
MKRDIFSELVEGFDALAKERQGKLTLRTYKVKLNALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp

>AT100171 NZ_CP027750:4347021-4347335 [Pseudomonas chlororaphis subsp. aureofaciens]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGTTTCGACGCCCTGGCCAAAGAGCGCCAAGGCAAGCTCACGCTGCG
CACCTACAAGGTCAAGCTGAACGCGCTGCTCCCGATCACCGCTGAAGAAGTGCTGGCCGTACGCGAGCAGTTGAACCTGT
CCAGATCGGTATTTGCCATGTACCTGCGCACCAATACTCGGACCCTGGAGAACTGGGAGCAAGGACGGGCAAAACCCAAC
GCTCAGGCCACTACCCTGATCCGCCTGGTACAGCGTTTTCCCGATACGGTGGAGCGGCTGGCAGCATTGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References