Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3497781..3498435 Replicon chromosome
Accession NZ_CP027728
Organism Pseudomonas sp. R2-37-08W

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4J93_RS16120 Protein ID WP_124429897.1
Coordinates 3497781..3498131 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4J93_RS16125 Protein ID WP_124429898.1
Coordinates 3498121..3498435 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J93_RS16110 3494541..3496073 + 1533 WP_025858974.1 NADH-quinone oxidoreductase subunit M -
C4J93_RS16115 3496081..3497544 + 1464 WP_124367423.1 NADH-quinone oxidoreductase subunit NuoN -
C4J93_RS16120 3497781..3498131 + 351 WP_124429897.1 toxin Toxin
C4J93_RS16125 3498121..3498435 + 315 WP_124429898.1 transcriptional regulator Antitoxin
C4J93_RS16130 3498500..3499252 - 753 WP_124429899.1 outer membrane beta-barrel protein -
C4J93_RS16135 3499505..3499741 + 237 WP_124363304.1 hypothetical protein -
C4J93_RS16140 3499784..3499981 - 198 WP_124367427.1 hypothetical protein -
C4J93_RS16145 3499996..3500175 - 180 WP_124429900.1 hypothetical protein -
C4J93_RS16150 3500290..3500799 + 510 WP_124430889.1 DUF3087 family protein -
C4J93_RS16155 3500794..3502167 - 1374 WP_124429901.1 MFS transporter -
C4J93_RS16160 3502285..3502674 - 390 WP_124407561.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13746.62 Da        Isoelectric Point: 9.7549

>T100031 WP_124429897.1 NZ_CP027728:3497781-3498131 [Pseudomonas sp. R2-37-08W]
MDALFIELPAFERHRRDYLSDELFHGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLTPQHKKALKHMLDREIKARAHNET

Download         Length: 351 bp

>T100031 NZ_CP027728:3497781-3498131 [Pseudomonas sp. R2-37-08W]
ATGGATGCTCTATTTATCGAACTGCCGGCATTCGAACGGCATCGCAGGGACTATCTGAGTGACGAGCTTTTCCACGGTTT
TCAACAGGAGCTGATGAAAAATCCGGAAGCGGGAGACGTGATCGAAGGAACGGGAGGGTTACGTAAGGTTCGCTTCGTCG
ATGAGCGACGAAACAAAGGCAAGCGTGGTGGCCTGCGGGTCATTTACTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACCTTGTATGGCAAACACGAACAGAGCGACCTGACGCCCCAACACAAGAAAGCCCTTAAACACATGCTGGACAGGGA
AATCAAAGCGAGAGCACACAATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11740.60 Da        Isoelectric Point: 10.6525

>AT100031 WP_124429898.1 NZ_CP027728:3498121-3498435 [Pseudomonas sp. R2-37-08W]
MKREIFSELVEGFDALADERQGKITLRTHKVHLNKLAPLTADEVIAVRQQLNLSRAVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT100031 NZ_CP027728:3498121-3498435 [Pseudomonas sp. R2-37-08W]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAGGCTTTGACGCCCTGGCCGACGAACGCCAGGGCAAAATCACCCTGCG
CACCCATAAAGTCCACCTTAACAAACTGGCGCCGCTCACTGCCGATGAGGTAATCGCCGTACGCCAGCAACTCAACCTGT
CCCGCGCGGTATTCGCCATGTACCTGCGTACCAACACCCGCACCCTAGAGAACTGGGAACAAGGCCGGGCCAAGCCCAAT
GCACAGGCTGTCACGTTGATACGACTGGTGGCGCGTTTTCCTGAAACCGTTGCGCAACTTGCCGCGCTGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References