Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3596546..3597200 Replicon chromosome
Accession NZ_CP027727
Organism Pseudomonas sp. R5-89-07

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4J94_RS16405 Protein ID WP_124387138.1
Coordinates 3596546..3596896 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4J94_RS16410 Protein ID WP_124387139.1
Coordinates 3596886..3597200 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J94_RS16395 3593304..3594836 + 1533 WP_010209575.1 NADH-quinone oxidoreductase subunit M -
C4J94_RS16400 3594844..3596307 + 1464 WP_124367423.1 NADH-quinone oxidoreductase subunit NuoN -
C4J94_RS16405 3596546..3596896 + 351 WP_124387138.1 toxin Toxin
C4J94_RS16410 3596886..3597200 + 315 WP_124387139.1 transcriptional regulator Antitoxin
C4J94_RS16415 3597254..3598006 - 753 WP_124387140.1 outer membrane beta-barrel protein -
C4J94_RS16420 3598132..3598965 - 834 WP_124387141.1 arylamine N-acetyltransferase -
C4J94_RS16425 3599086..3599322 + 237 WP_124387142.1 hypothetical protein -
C4J94_RS16430 3599353..3599547 - 195 WP_124387143.1 hypothetical protein -
C4J94_RS16435 3599563..3599742 - 180 WP_124388995.1 hypothetical protein -
C4J94_RS16440 3599857..3600378 + 522 WP_124387144.1 DUF3087 domain-containing protein -
C4J94_RS16445 3600392..3601522 - 1131 WP_124387145.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13737.61 Da        Isoelectric Point: 9.7548

>T100027 WP_124387138.1 NZ_CP027727:3596546-3596896 [Pseudomonas sp. R5-89-07]
MDALFIELPAFERHRRDYLSDELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLTPQHKKALKHMLDREIKARAHNET

Download         Length: 351 bp

>T100027 NZ_CP027727:3596546-3596896 [Pseudomonas sp. R5-89-07]
ATGGATGCTCTATTTATCGAACTGCCGGCATTCGAACGGCATCGCAGGGACTATCTGAGTGACGAGCTTTTCCAGGGCTT
TCAACAGGAACTGATGAAAAACCCGGAAGCGGGAGACGTGATCGAAGGAACGGGAGGGTTACGCAAGGTTCGCTTCGTCG
ATGAGCGACGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTACTACTGGTGGTCGGGCGGCACGCAATTCTGGTTA
TTCACCTTGTATGGCAAACACGAACAAAGCGACCTGACACCCCAACACAAGAAAGCCCTTAAACACATGCTGGACAGGGA
AATCAAAGCGAGAGCACACAATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11814.68 Da        Isoelectric Point: 10.6525

>AT100027 WP_124387139.1 NZ_CP027727:3596886-3597200 [Pseudomonas sp. R5-89-07]
MKREIFSELVEGFDALADERQGKITLRTHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAVLS

Download         Length: 315 bp

>AT100027 NZ_CP027727:3596886-3597200 [Pseudomonas sp. R5-89-07]
ATGAAACGTGAAATCTTTTCCGAACTGGTCGAAGGCTTCGACGCCTTGGCGGACGAACGTCAGGGCAAGATCACCCTGCG
CACCCACAAAGTCCACCTCAACAAACTGGCGCCGCTCACTGCCGACGAAGTGATCGCAGTGCGTCAGCAACTCAACCTTT
CCCGGTCGGTATTTGCCATGTATCTGCGTACCAATACCCGCACCCTGGAGAATTGGGAGCAAGGACGAGCAAAACCAAAC
GCACAGGCCGTTACGCTGATCCGCTTGGTGGCGCGCTTTCCGGAAACCGTGGCGCAACTCGCTGTATTGAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References