100020

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3612226..3612880 Replicon chromosome
Accession NZ_CP027726
Organism Pseudomonas orientalis strain R4-35-08

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C4J95_RS16455 Protein ID WP_124358909.1
Coordinates 3612226..3612576 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C4J95_RS16460 Protein ID WP_124358910.1
Coordinates 3612566..3612880 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C4J95_RS16445 3608985..3610517 + 1533 WP_003232072.1 NADH-quinone oxidoreductase subunit M -
C4J95_RS16450 3610525..3611988 + 1464 WP_124358908.1 NADH-quinone oxidoreductase subunit NuoN -
C4J95_RS16455 3612226..3612576 + 351 WP_124358909.1 toxin Toxin
C4J95_RS16460 3612566..3612880 + 315 WP_124358910.1 transcriptional regulator Antitoxin
C4J95_RS16465 3612938..3613690 - 753 WP_124358911.1 outer membrane beta-barrel protein -
C4J95_RS16470 3613922..3614158 + 237 WP_057721776.1 hypothetical protein -
C4J95_RS16475 3614202..3614396 - 195 WP_065884943.1 hypothetical protein -
C4J95_RS16480 3614411..3614590 - 180 WP_124358912.1 hypothetical protein -
C4J95_RS16485 3614706..3615227 + 522 WP_124358913.1 DUF3087 domain-containing protein -
C4J95_RS16490 3615255..3616619 - 1365 WP_124358914.1 MFS transporter -
C4J95_RS16495 3616736..3617125 - 390 WP_124358915.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13756.70 Da        Isoelectric Point: 9.6569

>T100020 WP_124358909.1 NZ_CP027726:3612226-3612576 [Pseudomonas orientalis]
MDALFIELPAFERHRKDYLSDELFHGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLAPQYKKALKHMLDREIKARIHNET

Download         Length: 351 bp

>T100020 NZ_CP027726:3612226-3612576 [Pseudomonas orientalis]
ATGGATGCTCTATTTATCGAACTGCCGGCCTTCGAGCGGCATCGCAAGGACTATCTGAGTGACGAGCTTTTCCACGGTTT
TCAACAGGAGTTGATGAAAAACCCCGAAGCGGGAGACGTTATCGAAGGAACGGGAGGGTTACGCAAGGTTCGCTTCGTCG
ATGAGCGACGAAACAAAGGCAAACGCGGTGGCCTGCGGGTCATTTATTACTGGTGGTCAGGCGGCACGCAATTCTGGTTA
TTCACTTTGTACGGCAAGCACGAACAGAGCGACCTGGCACCGCAGTACAAGAAAGCCCTTAAACACATGCTAGACAGGGA
AATCAAAGCGAGAATACACAATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11726.58 Da        Isoelectric Point: 10.6525

>AT100020 WP_124358910.1 NZ_CP027726:3612566-3612880 [Pseudomonas orientalis]
MKRDIFSELVEGFDALADERQGKITLRTHKVHLNKLAPLTADEVIAVRQQLNLSRAVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp

>AT100020 NZ_CP027726:3612566-3612880 [Pseudomonas orientalis]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGCTTCGACGCCCTGGCTGATGAACGCCAGGGAAAAATCACCCTGCG
CACCCACAAAGTGCACCTCAACAAGCTGGCGCCGCTTACCGCGGACGAGGTAATCGCCGTACGCCAGCAACTCAACCTGT
CCCGCGCGGTATTCGCCATGTACCTGCGTACCAACACCCGGACCCTGGAAAACTGGGAACAAGGCCGGGCCAAGCCAAAT
GCACAGGCAGTCACGCTGATACGGCTGGTGGCGCGTTTTCCCGAGACCGTGGCGCAACTGGCCGCACTGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References