MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 202690 bp
Accession: NZ_OU016028        Location: 1..202690         Organism: Enterococcus faecium isolate USZ_VRE67_P60       Replicon: plasmid pl1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KKQ96_RS14035 1..1041 + 1041 WP_002326172.1 replication initiator protein A -
KKQ96_RS14040 1865..2197 + 333 WP_002323647.1 type IV conjugative transfer system protein TraE -
KKQ96_RS14045 2816..3157 + 342 WP_002295674.1 DUF5406 family protein -
KKQ96_RS14050 3394..4644 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
KKQ96_RS14055 5054..5293 + 240 WP_002295673.1 hypothetical protein -
KKQ96_RS14060 5360..5569 + 210 WP_002295672.1 hypothetical protein -
KKQ96_RS14065 5629..6300 + 672 WP_002336710.1 class A sortase -
KKQ96_RS14070 6353..8329 + 1977 WP_010729784.1 SpaA isopeptide-forming pilin-related protein -
KKQ96_RS14075 8342..9097 + 756 WP_010729785.1 hypothetical protein VF
KKQ96_RS14080 9094..9918 + 825 WP_002350398.1 pilin N-terminal domain-containing protein -
KKQ96_RS14085 10219..12318 + 2100 WP_010729786.1 isopeptide-forming domain-containing fimbrial protein -
KKQ96_RS14090 12356..14413 - 2058 WP_002350400.1 hypothetical protein VF
KKQ96_RS14095 14527..14739 - 213 WP_002296354.1 hypothetical protein -
KKQ96_RS14100 14926..15393 + 468 WP_002296355.1 hypothetical protein -
KKQ96_RS14105 15390..15632 + 243 WP_002321279.1 DUF5415 family protein -
KKQ96_RS14110 15650..15952 + 303 WP_002296358.1 hypothetical protein -
KKQ96_RS14115 16024..18078 + 2055 WP_059355965.1 hypothetical protein -
KKQ96_RS14120 18078..20690 + 2613 WP_059355955.1 type IV secretory system conjugative DNA transfer family protein -
KKQ96_RS14125 20687..23218 + 2532 WP_002321282.1 hypothetical protein -
KKQ96_RS14130 23270..23602 + 333 WP_002326876.1 hypothetical protein -
KKQ96_RS14135 23603..24196 + 594 WP_002313112.1 hypothetical protein -
KKQ96_RS14140 24359..26005 + 1647 Protein_21 ATPase -
KKQ96_RS14145 26741..28618 + 1878 WP_002305177.1 group II intron reverse transcriptase/maturase -
KKQ96_RS14150 28749..29126 + 378 Protein_23 ATPase -
KKQ96_RS14155 29126..30331 + 1206 WP_002296365.1 glucosaminidase domain-containing protein -
KKQ96_RS14160 30347..30991 + 645 WP_002296371.1 hypothetical protein -
KKQ96_RS14165 31002..31808 + 807 WP_060809402.1 hypothetical protein -
KKQ96_RS14170 31830..32060 + 231 WP_002313120.1 hypothetical protein -
KKQ96_RS14175 32606..32881 + 276 WP_002325546.1 hypothetical protein -
KKQ96_RS14180 32923..33345 + 423 WP_002330592.1 hypothetical protein -
KKQ96_RS14185 33364..34956 + 1593 WP_002330591.1 hypothetical protein Relaxase
KKQ96_RS14190 34968..35303 + 336 WP_002330590.1 hypothetical protein -
KKQ96_RS14195 35418..36377 - 960 WP_002301399.1 IS30 family transposase IS1062 Transposase
KKQ96_RS14200 36521..36715 + 195 WP_002330589.1 hypothetical protein -
KKQ96_RS14205 36747..39119 + 2373 WP_059355962.1 ArdC-like ssDNA-binding domain-containing protein -
KKQ96_RS14210 39180..40640 + 1461 WP_010729792.1 toprim domain-containing protein -
KKQ96_RS14215 40651..42855 + 2205 WP_059355967.1 type IA DNA topoisomerase -
KKQ96_RS14220 42871..43020 + 150 WP_002295632.1 hypothetical protein -
KKQ96_RS14225 43094..43687 + 594 WP_002330563.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
KKQ96_RS14230 43703..44602 + 900 WP_002322787.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
KKQ96_RS14235 44605..45090 + 486 WP_002296241.1 single-stranded DNA-binding protein -
KKQ96_RS14240 45456..45716 + 261 WP_002296240.1 hypothetical protein -
KKQ96_RS14245 46157..46363 + 207 WP_002296239.1 hypothetical protein -
KKQ96_RS14250 46363..46614 + 252 WP_002296238.1 hypothetical protein -
KKQ96_RS14255 46629..47066 + 438 WP_002296237.1 hypothetical protein -
KKQ96_RS14260 47059..47766 + 708 WP_002353391.1 hypothetical protein -
KKQ96_RS15735 47931..48131 + 201 WP_002330566.1 hypothetical protein -
KKQ96_RS14265 48147..48326 + 180 WP_002305761.1 hypothetical protein -
KKQ96_RS14270 48667..48930 + 264 WP_002287514.1 hypothetical protein Antitoxin Detail
KKQ96_RS14275 48924..49274 + 351 WP_213313539.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
KKQ96_RS14280 49298..49912 - 615 WP_010729795.1 Tn3 family transposase TnpR_TnAs2 Transposase
KKQ96_RS14285 50226..50648 + 423 WP_002288787.1 hypothetical protein -
KKQ96_RS14290 50658..50861 + 204 WP_002299573.1 hypothetical protein -
KKQ96_RS14295 51072..51656 + 585 WP_002299575.1 Tn3 family transposase TnBth3 Transposase
KKQ96_RS14300 51845..52525 - 681 WP_010861579.1 IS6 family transposase IS1216E Transposase
KKQ96_RS14305 52601..53244 - 644 Protein_55 transposase -
KKQ96_RS14310 53519..54061 + 543 WP_002298088.1 hypothetical protein -
KKQ96_RS14315 54217..54666 + 450 WP_010729386.1 TlpA disulfide reductase family protein -
KKQ96_RS14325 55934..56089 + 156 Protein_59 4Fe-4S binding protein -
KKQ96_RS14330 56108..57385 + 1278 WP_002301194.1 ABC transporter permease -
KKQ96_RS14335 57395..58051 + 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
KKQ96_RS14340 58051..59427 + 1377 WP_002301195.1 ABC transporter permease -
KKQ96_RS14345 59557..60756 + 1200 WP_010729384.1 IS256 family transposase ISBsu2 Transposase
KKQ96_RS14350 60728..62224 + 1497 WP_077974472.1 IS1182 family transposase ISEfa7 Transposase
KKQ96_RS15740 62701..62850 + 150 WP_002299930.1 hypothetical protein -
KKQ96_RS14355 62896..63429 + 534 WP_002389935.1 hypothetical protein -
KKQ96_RS14360 63573..64862 + 1290 WP_002299928.1 ABC transporter substrate-binding protein -
KKQ96_RS14365 64947..65819 + 873 WP_002299927.1 sugar ABC transporter permease -
KKQ96_RS14370 65809..66624 + 816 WP_002299926.1 carbohydrate ABC transporter permease -
KKQ96_RS14375 66640..67764 + 1125 WP_002299925.1 Oligosaccharides import ATP-binding protein MsmX VF
KKQ96_RS14380 67742..68545 + 804 WP_002299923.1 metallophosphoesterase -
KKQ96_RS14385 69005..69268 + 264 WP_002389939.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
KKQ96_RS14390 69252..69587 + 336 WP_014748798.1 type II toxin-antitoxin system PemK/MazF family toxin -
KKQ96_RS14395 69766..70980 - 1215 Protein_74 ISL3 family transposase ISEfa11 Transposase
KKQ96_RS14400 71181..72455 + 1275 WP_010729381.1 ISL3 family transposase IS1476 Transposase
KKQ96_RS14405 72838..73566 - 729 WP_002302980.1 helix-turn-helix domain-containing protein -
KKQ96_RS14410 73544..75118 - 1575 WP_002340467.1 histidine kinase -
KKQ96_RS14415 75347..76285 + 939 WP_002304874.1 sugar ABC transporter permease -
KKQ96_RS14420 76297..77208 + 912 WP_002289655.1 carbohydrate ABC transporter permease -
KKQ96_RS14425 77232..78704 + 1473 WP_010729380.1 extracellular solute-binding protein -
KKQ96_RS14430 78755..79366 + 612 WP_002304878.1 DUF624 domain-containing protein -
KKQ96_RS14435 79396..81309 + 1914 WP_002304880.1 beta-N-acetylhexosaminidase -
KKQ96_RS14440 81437..84418 + 2982 WP_002305865.1 glycoside hydrolase family 2 TIM barrel-domain containing protein -
KKQ96_RS14445 84415..86076 + 1662 WP_002288608.1 hypothetical protein VF
KKQ96_RS14450 86116..87048 + 933 WP_002288609.1 hypothetical protein -
KKQ96_RS14455 87440..88987 - 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
KKQ96_RS14460 89089..89442 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
KKQ96_RS14465 89432..89626 - 195 WP_002285758.1 hypothetical protein -
KKQ96_RS14470 89852..91054 - 1203 WP_010729379.1 site-specific integrase -
KKQ96_RS14475 91057..91251 - 195 WP_002351139.1 DUF3173 domain-containing protein -
KKQ96_RS14480 91298..92146 - 849 WP_010729378.1 rep protein -
KKQ96_RS14485 92351..92701 - 351 WP_010729377.1 hypothetical protein -
KKQ96_RS15745 92879..93742 + 864 WP_010729376.1 helix-turn-helix transcriptional regulator -
KKQ96_RS14495 94366..95358 + 993 WP_005233042.1 ABC transporter permease subunit -
KKQ96_RS14500 95374..96258 + 885 WP_005230433.1 carbohydrate ABC transporter permease -
KKQ96_RS14505 96307..97914 + 1608 WP_010729375.1 ABC transporter substrate-binding protein -
KKQ96_RS14510 97915..99399 + 1485 WP_010729374.1 glycoside hydrolase family 32 protein -
KKQ96_RS14515 99576..100568 + 993 WP_010729373.1 LacI family DNA-binding transcriptional regulator -
KKQ96_RS14520 100620..101489 + 870 WP_010729372.1 ROK family protein -
KKQ96_RS14525 101909..103522 - 1614 WP_002288610.1 glutamine-hydrolyzing GMP synthase -
KKQ96_RS14530 103529..104803 - 1275 WP_060855706.1 ISL3 family transposase IS1476 Transposase
KKQ96_RS14535 105091..105744 + 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
KKQ96_RS14540 105741..107060 + 1320 WP_002300494.1 HAMP domain-containing sensor histidine kinase -
KKQ96_RS14545 107162..107842 - 681 WP_002325565.1 IS6 family transposase IS1216E Transposase
KKQ96_RS14550 107973..108425 + 453 WP_000751236.1 hypothetical protein -
KKQ96_RS14555 108439..109128 + 690 WP_000718009.1 hypothetical protein -
KKQ96_RS14560 109253..111604 + 2352 WP_000344083.1 DUF1906 domain-containing protein -
KKQ96_RS14565 111693..112079 + 387 WP_000391061.1 hypothetical protein -
KKQ96_RS14570 112404..113021 + 618 WP_001224538.1 Tn3 family transposase TnpR_TnAs2 Transposase
KKQ96_RS14575 113062..113361 + 300 WP_000366408.1 BRCT domain-containing protein -
KKQ96_RS14580 113395..113562 + 168 WP_000824191.1 hypothetical protein -
KKQ96_RS14585 113607..114212 - 606 WP_002321606.1 Tn3 family transposase TnpR_ISPa40 Transposase
KKQ96_RS15810 114337..114459 + 123 WP_010729369.1 hypothetical protein -
KKQ96_RS14590 114472..115152 - 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
KKQ96_RS14595 115152..115325 - 174 WP_010729368.1 hypothetical protein -
KKQ96_RS14600 115620..116171 - 552 WP_002303113.1 DUF334 domain-containing protein -
KKQ96_RS14605 116266..116646 - 381 Protein_117 IS6 family transposase IS1216V Transposase
KKQ96_RS14610 116716..117396 + 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
KKQ96_RS14615 117740..117994 + 255 Protein_119 replication initiation protein -
KKQ96_RS14620 118064..118576 + 513 WP_002387940.1 IS3 family transposase ISPa31 Transposase
KKQ96_RS14625 118573..119610 + 1038 WP_002303110.1 IS3 family transposase ISSde10 Transposase
KKQ96_RS14630 119770..119946 + 177 Protein_122 IS6 family transposase -
KKQ96_RS14635 120001..121311 + 1311 Protein_123 Bifunctional AAC/APH ARG
KKQ96_RS14640 121510..122190 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
KKQ96_RS14645 122530..123699 - 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
KKQ96_RS14650 123937..124221 + 285 WP_074398953.1 Gfo/Idh/MocA family oxidoreductase -
KKQ96_RS14655 124259..124939 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
KKQ96_RS14660 124921..125703 + 783 WP_255310292.1 PTS transporter subunit IIC -
KKQ96_RS14665 125737..126021 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
KKQ96_RS14670 126023..126538 + 516 WP_002300840.1 YjbQ family protein -
KKQ96_RS14675 126554..127216 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
KKQ96_RS14680 127223..127795 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
KKQ96_RS14685 127982..129502 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
KKQ96_RS14690 129745..129930 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
KKQ96_RS14695 129914..130096 - 183 WP_002300846.1 hypothetical protein -
KKQ96_RS14700 130337..130555 + 219 Protein_136 IS256 family transposase ISLgar5 Transposase
KKQ96_RS14705 131050..131649 + 600 WP_002301839.1 Tyrosine recombinase XerC VF
KKQ96_RS14710 131713..132312 + 600 WP_002322465.1 AbiH family protein -
KKQ96_RS14715 132342..132993 - 652 Protein_139 IS6 family transposase IS1216V Transposase
KKQ96_RS14720 133328..134200 - 873 WP_002292418.1 ROK family protein -
KKQ96_RS14725 134464..136410 - 1947 WP_002293868.1 sucrose-specific PTS transporter subunit IIBC -
KKQ96_RS14730 136595..138034 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
KKQ96_RS14735 138036..138998 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
KKQ96_RS14740 139219..140514 - 1296 WP_002297218.1 ISL3 family transposase ISEfa11 Transposase
KKQ96_RS14745 140690..142116 - 1427 Protein_145 IS3 family transposase ISEfa10 Transposase
KKQ96_RS14750 142359..142814 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
KKQ96_RS14755 143079..143177 + 99 Protein_147 IS30 family transposase -
KKQ96_RS14760 143400..143630 - 231 WP_002289255.1 resolvase -
KKQ96_RS14765 143860..144678 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
KKQ96_RS14770 144839..145528 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
KKQ96_RS14775 145542..147044 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
KKQ96_RS14780 147057..147533 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
KKQ96_RS14785 147630..147740 - 111 Protein_153 transposase -
KKQ96_RS14795 150311..150829 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
KKQ96_RS14800 151966..152373 - 408 WP_002329899.1 type II toxin-antitoxin system death-on-curing family toxin -
KKQ96_RS14805 152370..152603 - 234 WP_002290351.1 addiction module antitoxin -
KKQ96_RS14810 152937..154022 + 1086 WP_002290352.1 tyrosine recombinase XerS -
KKQ96_RS14815 154306..154971 - 666 WP_002324528.1 site-specific integrase -
KKQ96_RS14820 155125..155274 - 150 WP_002290356.1 hypothetical protein -
KKQ96_RS14825 155267..155476 - 210 WP_002290357.1 DUF3173 domain-containing protein -
KKQ96_RS14830 155798..156904 - 1107 Protein_162 IS4 family transposase IS641 Transposase
KKQ96_RS14835 156981..158441 - 1461 WP_002335326.1 sucrose phosphorylase -
KKQ96_RS14840 158438..159658 - 1221 WP_002342361.1 alpha-amylase family glycosyl hydrolase -
KKQ96_RS14845 159719..161902 - 2184 WP_002290367.1 alpha-galactosidase -
KKQ96_RS14850 161942..162772 - 831 WP_002290368.1 carbohydrate ABC transporter permease -
KKQ96_RS14855 162784..163656 - 873 WP_002290370.1 sugar ABC transporter permease -
KKQ96_RS14860 163666..164925 - 1260 WP_002290371.1 extracellular solute-binding protein -
KKQ96_RS14865 165073..166383 - 1311 WP_002329911.1 alpha-glucosidase/alpha-galactosidase -
KKQ96_RS14870 166415..167239 - 825 WP_002350071.1 carbohydrate ABC transporter permease -
KKQ96_RS14875 167255..168151 - 897 Protein_171 sugar ABC transporter permease -
KKQ96_RS14880 168234..169346 - 1113 Protein_172 sugar ABC transporter substrate-binding protein -
KKQ96_RS15815 169374..169499 - 126 WP_002290377.1 hypothetical protein -
KKQ96_RS14885 169637..170662 - 1026 WP_002338088.1 LacI family DNA-binding transcriptional regulator -
KKQ96_RS14890 170907..172178 - 1272 WP_002290379.1 substrate-binding domain-containing protein -
KKQ96_RS15750 172462..172833 - 372 WP_002290380.1 VOC family protein -
KKQ96_RS15755 172873..173409 - 537 WP_002342357.1 VOC family protein -
KKQ96_RS14900 173457..173894 + 438 WP_229033435.1 IS91 family transposase ISCARN110 Transposase
KKQ96_RS14905 174067..174621 - 555 WP_002290383.1 tyrosine-type recombinase/integrase -
KKQ96_RS14910 175094..176263 - 1170 WP_002300314.1 IS256 family transposase ISEfa13 Transposase
KKQ96_RS14915 177283..177822 - 540 WP_010728942.1 hypothetical protein -
KKQ96_RS14920 177962..178642 - 681 Protein_182 IS6 family transposase IS1297 Transposase
KKQ96_RS14925 178964..179185 - 222 WP_002311006.1 hypothetical protein -
KKQ96_RS14930 179283..179585 - 303 WP_002350363.1 hypothetical protein -
KKQ96_RS14935 179768..180382 + 615 Protein_185 Tn3 family transposase TnBth3 Transposase
KKQ96_RS14940 180752..181753 - 1002 WP_002344895.1 DUF4062 domain-containing protein -
KKQ96_RS14945 181912..182178 - 267 WP_002344896.1 helix-turn-helix transcriptional regulator -
KKQ96_RS14950 182168..182524 - 357 WP_002344897.1 type II toxin-antitoxin system RelE/ParE family toxin -
KKQ96_RS14955 182659..183339 + 681 WP_001015311.1 IS6 family transposase IS1216E Transposase
KKQ96_RS14960 183551..183736 - 186 Protein_190 type I restriction endonuclease subunit S -
KKQ96_RS14965 183792..184472 - 681 WP_213313538.1 IS6 family transposase IS1297 Transposase
KKQ96_RS14970 184618..184779 - 162 WP_002349958.1 hypothetical protein -
KKQ96_RS14975 185039..185587 - 549 WP_002292681.1 hypothetical protein -
KKQ96_RS14980 185588..186445 - 858 WP_002292680.1 ParA family protein -
KKQ96_RS14985 186729..187015 - 287 Protein_195 type II toxin-antitoxin system RelE/ParE family toxin -
KKQ96_RS14990 187005..187334 - 330 WP_002292678.1 AbrB family transcriptional regulator -
KKQ96_RS14995 187411..187683 - 273 WP_002314366.1 Txe/YoeB family addiction module toxin Toxin Detail
KKQ96_RS15000 187683..187946 - 264 WP_002297422.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
KKQ96_RS15005 188180..189088 + 909 Protein_199 IS982 family transposase ISEfm1 Transposase
KKQ96_RS15010 189091..190266 - 1176 WP_002336205.1 MFS transporter -
KKQ96_RS15015 190269..192518 - 2250 WP_002314387.1 alpha-galactosidase -
KKQ96_RS15020 192615..193406 - 792 Protein_202 AraC family transcriptional regulator -
KKQ96_RS15025 193568..194716 - 1149 WP_002287525.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ96_RS15030 194733..195137 - 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ96_RS15035 195442..196350 - 909 Protein_205 IS982 family transposase ISEfm1 Transposase
KKQ96_RS15040 196444..197379 - 936 WP_002323400.1 hypothetical protein -
KKQ96_RS15045 197938..198255 - 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
KKQ96_RS15050 198256..198510 - 255 WP_002323399.1 hypothetical protein -
KKQ96_RS15055 198869..199273 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ96_RS15060 199290..200438 + 1149 WP_002287525.1 IS200-IS605 family transposase ISEfa4 Transposase
KKQ96_RS15760 200661..200801 - 141 WP_002290398.1 hypothetical protein -
KKQ96_RS15075 201439..201525 - 87 Protein_212 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance