MGE detailed information
MGE type: Conjugative plasmid MGE length: 157174 bp
Accession: NZ_LT906556 Location: 1..157174 Organism: Escherichia coli isolate E. coli RL465 Replicon: plasmid I
Accession: NZ_LT906556 Location: 1..157174 Organism: Escherichia coli isolate E. coli RL465 Replicon: plasmid I
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| RL465_RS23625 () | 479..1381 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| RL465_RS23630 () | 1450..2559 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| RL465_RS23635 () | 2992..3945 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| RL465_RS23640 () | 4049..4438 | + | 390 | WP_001332050.1 | outer membrane protease | - |
| RL465_RS23645 () | 5155..5852 | + | 698 | Protein_4 | IS1 family transposase | - |
| RL465_RS23650 () | 5846..6127 | - | 282 | WP_072834405.1 | hypothetical protein | - |
| RL465_RS23655 () | 6268..8094 | - | 1827 | WP_001339650.1 | AAA family ATPase | - |
| RL465_RS23660 () | 8097..8582 | - | 486 | WP_001015823.1 | hypothetical protein | - |
| RL465_RS23665 () | 8572..9672 | - | 1101 | WP_072714138.1 | hypothetical protein | - |
| RL465_RS23670 () | 10202..10351 | - | 150 | Protein_9 | IS3 family transposase IS2 | Transposase |
| RL465_RS23675 () | 10529..11722 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| RL465_RS23680 () | 12945..14181 | - | 1237 | Protein_11 | IS3 family transposase IS2 | Transposase |
| RL465_RS23685 () | 14808..15101 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| RL465_RS23690 () | 15159..15358 | - | 200 | Protein_13 | lysis system i-spanin subunit Rz | - |
| RL465_RS23695 () | 15912..17011 | + | 1100 | Protein_14 | IS481 family transposase ISKpn28 | Transposase |
| RL465_RS23700 () | 18247..19362 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| RL465_RS23705 () | 19502..23161 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| RL465_RS23710 () | 23265..24494 | + | 1230 | WP_001552738.1 | Enterochelin esterase | VF |
| RL465_RS23715 () | 24579..25535 | + | 957 | WP_000271276.1 | hypothetical protein | VF |
| RL465_RS23720 () | 25580..27757 | - | 2178 | WP_072657522.1 | Ferric enterobactin receptor | VF |
| RL465_RS23725 () | 28612..29586 | - | 975 | Protein_20 | 3-deoxy-7-phosphoheptulonate synthase | - |
| RL465_RS23730 () | 29556..30253 | - | 698 | Protein_21 | IS1 family transposase | - |
| RL465_RS23735 () | 30305..30379 | - | 75 | Protein_22 | colicin | - |
| RL465_RS23740 () | 30357..30593 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| RL465_RS23745 () | 31057..31338 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| RL465_RS23750 () | 31511..31678 | + | 168 | Protein_25 | colicin-B | - |
| RL465_RS23755 () | 31696..32223 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| RL465_RS23760 () | 32467..33282 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| RL465_RS23765 () | 33332..33685 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| RL465_RS23770 () | 33863..34654 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| RL465_RS23775 () | 34651..35340 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| RL465_RS23780 () | 35384..35734 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| RL465_RS23785 () | 36305..36565 | + | 261 | WP_000343102.1 | hypothetical protein | - |
| RL465_RS23790 () | 36562..37152 | + | 591 | WP_000194555.1 | hypothetical protein | - |
| RL465_RS23795 () | 37170..37517 | - | 348 | WP_000142424.1 | hypothetical protein | - |
| RL465_RS23800 () | 37636..37983 | + | 348 | WP_000762580.1 | hypothetical protein | - |
| RL465_RS23805 () | 38001..39881 | - | 1881 | WP_001283356.1 | colicin | - |
| RL465_RS23810 () | 40160..41506 | - | 1347 | WP_001132019.1 | hypothetical protein | - |
| RL465_RS23815 () | 41860..42462 | + | 603 | WP_000517689.1 | hypothetical protein | - |
| RL465_RS23820 () | 42518..43012 | + | 495 | WP_001442119.1 | hypothetical protein | - |
| RL465_RS23825 () | 43012..43278 | + | 267 | WP_000627831.1 | hypothetical protein | - |
| RL465_RS23830 () | 43755..44171 | - | 417 | WP_031610367.1 | hypothetical protein | - |
| RL465_RS23835 () | 44180..47146 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| RL465_RS23840 () | 47149..47667 | - | 519 | WP_001133513.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| RL465_RS23845 () | 47726..48430 | + | 705 | WP_001067856.1 | IS6 family transposase IS15DII | Transposase |
| RL465_RS23850 () | 48484..48819 | - | 336 | Protein_45 | hypothetical protein | - |
| RL465_RS23855 () | 48808..49215 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| RL465_RS23860 () | 49353..50237 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| RL465_RS23865 () | 50269..51468 | - | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| RL465_RS23870 () | 51574..52224 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| RL465_RS23875 () | 52256..52498 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| RL465_RS23880 () | 52540..52812 | - | 273 | Protein_51 | Tn3 family transposase | - |
| RL465_RS23885 () | 52878..53582 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| RL465_RS23890 () | 53636..53893 | + | 258 | Protein_53 | IS91 family transposase ISPps1 | Transposase |
| RL465_RS23895 () | 54000..54836 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| RL465_RS23900 () | 54836..55639 | - | 804 | WP_074417338.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| RL465_RS23905 () | 55700..56515 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| RL465_RS23910 () | 56852..57055 | + | 204 | WP_000131876.1 | hypothetical protein | - |
| RL465_RS23915 () | 57046..57267 | + | 222 | WP_001251694.1 | hypothetical protein | - |
| RL465_RS23920 () | 57502..58488 | - | 987 | WP_000852935.1 | hypothetical protein | Relaxase |
| RL465_RS23925 () | 59753..60310 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| RL465_RS23930 () | 60493..61353 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| RL465_RS23935 () | 61514..62011 | + | 498 | Protein_62 | mercuric reductase | - |
| RL465_RS23940 () | 62029..62391 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| RL465_RS23945 () | 62388..62624 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| RL465_RS23950 () | 62660..63328 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| RL465_RS23955 () | 63403..64653 | + | 1251 | Protein_66 | DDE-type integrase/transposase/recombinase | - |
| RL465_RS23960 () | 64718..65422 | + | 705 | Protein_67 | IS6 family transposase IS26 | Transposase |
| RL465_RS23965 () | 65612..66427 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| RL465_RS23970 () | 66578..67282 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| RL465_RS23975 () | 67355..67594 | + | 240 | Protein_70 | macrolide transporter | - |
| RL465_RS23980 () | 67740..68603 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| RL465_RS23985 () | 68641..68886 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| RL465_RS23990 () | 69355..70146 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| RL465_RS23995 () | 70149..70424 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| RL465_RS24000 () | 70426..71061 | + | 636 | Protein_75 | IS256 family transposase IS406 | Transposase |
| RL465_RS24005 () | 71326..71658 | - | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| RL465_RS24010 () | 71828..72619 | - | 792 | WP_001206316.1 | Streptomycin 3''-adenylyltransferase | ARG |
| RL465_RS24015 () | 72712..73185 | - | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| RL465_RS24020 () | 73342..74355 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| RL465_RS24025 () | 74558..74908 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| RL465_RS24030 () | 75084..75644 | + | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| RL465_RS24035 () | 75648..78614 | + | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| RL465_RS24040 () | 78672..78914 | + | 243 | WP_000844627.1 | transposase | - |
| RL465_RS24045 () | 78946..79596 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| RL465_RS24050 () | 79702..80901 | + | 1200 | WP_001493765.1 | Tetracycline resistance protein, class C | ARG |
| RL465_RS24055 () | 80933..81817 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| RL465_RS24060 () | 81955..82362 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| RL465_RS24065 () | 82351..83100 | + | 750 | Protein_88 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| RL465_RS24070 () | 83124..83729 | - | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| RL465_RS24075 () | 83824..86721 | + | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| RL465_RS24080 () | 86858..87259 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| RL465_RS24085 () | 87192..87449 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| RL465_RS24090 () | 87542..88195 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| RL465_RS24095 () | 89134..89991 | - | 858 | WP_065800511.1 | incFII family plasmid replication initiator RepA | - |
| RL465_RS24100 () | 89984..90058 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| RL465_RS24105 () | 90293..90553 | - | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| RL465_RS24110 () | 91495..94350 | - | 2856 | WP_053320759.1 | chromosome segregation protein SMC | - |
| RL465_RS24115 () | 94415..96448 | - | 2034 | WP_000887497.1 | N-6 DNA methylase | - |
| RL465_RS24120 () | 96494..99043 | - | 2550 | WP_053320758.1 | DEAD/DEAH box helicase family protein | - |
| RL465_RS24125 () | 99329..99541 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| RL465_RS24130 () | 99677..100237 | - | 561 | WP_024184455.1 | fertility inhibition protein FinO | - |
| RL465_RS24135 () | 100292..101035 | - | 744 | WP_000205704.1 | conjugal transfer pilus acetylase TraX | - |
| RL465_RS24140 () | 101055..106325 | - | 5271 | WP_053320757.1 | Multifunctional conjugation protein TraI | Relaxase |
| RL465_RS24145 () | 106325..108505 | - | 2181 | WP_074417192.1 | type IV conjugative transfer system coupling protein TraD | - |
| RL465_RS24150 () | 108758..109489 | - | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| RL465_RS24155 () | 109521..110024 | - | 504 | WP_053320762.1 | surface exclusion protein | - |
| RL465_RS24160 () | 110039..112861 | - | 2823 | WP_053320755.1 | conjugal transfer mating pair stabilization protein TraG | - |
| RL465_RS24165 () | 112858..114231 | - | 1374 | WP_065800514.1 | conjugal transfer protein TraH | - |
| RL465_RS24170 () | 114231..114593 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| RL465_RS24175 () | 114664..117015 | - | 2352 | Protein_110 | type IV secretion system protein TraC | - |
| RL465_RS24180 () | 117175..117396 | - | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| RL465_RS24185 () | 117531..118046 | - | 516 | WP_000724019.1 | type IV conjugative transfer system lipoprotein TraV | - |
| RL465_RS24190 () | 118043..118411 | - | 369 | WP_071787938.1 | conjugal transfer protein TrbD | - |
| RL465_RS24195 () | 118350..118937 | - | 588 | WP_053320746.1 | conjugal transfer protein TraP | - |
| RL465_RS24200 () | 118927..120354 | - | 1428 | WP_000146672.1 | conjugal transfer protein TraB | - |
| RL465_RS24205 () | 120354..121058 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| RL465_RS24210 () | 121069..121635 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| RL465_RS24215 () | 121657..121968 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| RL465_RS24220 () | 121973..122335 | - | 363 | WP_000994784.1 | type IV conjugative transfer system pilin TraA | - |
| RL465_RS24225 () | 122368..122763 | - | 396 | WP_053320748.1 | conjugal transfer relaxosome protein TraY | - |
| RL465_RS24230 () | 122862..123551 | - | 690 | WP_000283380.1 | conjugal transfer transcriptional regulator TraJ | - |
| RL465_RS24235 () | 123738..124121 | - | 384 | WP_053320747.1 | relaxosome protein TraM | - |
| RL465_RS24240 () | 124442..125044 | + | 603 | WP_000243709.1 | hypothetical protein | VF |
| RL465_RS24245 () | 125341..126162 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| RL465_RS24250 () | 126284..126571 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| RL465_RS24255 () | 126596..126802 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| RL465_RS24260 () | 127493..127651 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 127695..127919 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 127695..127919 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 127695..127919 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 127695..127919 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| RL465_RS24265 () | 127731..127919 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| RL465_RS24270 () | 127931..128650 | - | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| RL465_RS24275 () | 128647..129081 | - | 435 | WP_000845934.1 | conjugation system SOS inhibitor PsiB | - |
| RL465_RS24280 () | 129136..131094 | - | 1959 | WP_023148339.1 | ParB/RepB/Spo0J family partition protein | - |
| RL465_RS24285 () | 131160..131393 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| RL465_RS24290 () | 131456..131995 | - | 540 | WP_000290791.1 | single-stranded DNA-binding protein | - |
| RL465_RS24295 () | 132468..132716 | - | 249 | WP_071606928.1 | hypothetical protein | - |
| RL465_RS24300 () | 132868..133431 | - | 564 | WP_001299724.1 | class I SAM-dependent methyltransferase | - |
| RL465_RS24305 () | 133480..134841 | - | 1362 | WP_000170715.1 | DUF3560 domain-containing protein | - |
| RL465_RS24310 () | 134893..135123 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| RL465_RS24315 () | 135637..136153 | + | 517 | Protein_138 | hypothetical protein | - |
| RL465_RS24320 () | 136123..136314 | - | 192 | WP_065800505.1 | hypothetical protein | - |
| RL465_RS24325 () | 136311..136775 | - | 465 | WP_072657562.1 | DUF1380 family protein | - |
| RL465_RS24330 () | 136775..137077 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| RL465_RS24335 () | 137602..138366 | + | 765 | Protein_142 | IS110 family transposase ISEc32 | Transposase |
| RL465_RS24340 () | 138380..139077 | - | 698 | Protein_143 | IS1 family transposase | - |
| RL465_RS24345 () | 139131..139463 | - | 333 | Protein_144 | hypothetical protein | - |
| RL465_RS24350 () | 139532..139870 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| RL465_RS24355 () | 140811..141782 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| RL465_RS24360 () | 141782..142948 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| RL465_RS24365 () | 143248..143945 | - | 698 | Protein_148 | IS1 family transposase | - |
| RL465_RS24370 () | 144101..145603 | - | 1503 | WP_072657541.1 | hypothetical protein | - |
| RL465_RS24375 () | 146223..146672 | - | 450 | WP_000238252.1 | hypothetical protein | - |
| RL465_RS24380 () | 146790..147269 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| RL465_RS24385 () | 147709..147936 | + | 228 | Protein_152 | malate dehydrogenase | - |
| RL465_RS24390 () | 147933..148064 | - | 132 | Protein_153 | phosphopyruvate hydratase | - |
| RL465_RS24395 () | 148062..148319 | + | 258 | Protein_154 | Tn3 family transposase | - |
| RL465_RS24400 () | 148553..149410 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| RL465_RS24405 () | 149407..150264 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| RL465_RS24410 () | 150261..151088 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| RL465_RS24415 () | 151088..152002 | - | 915 | WP_000949005.1 | putative periplasmic iron-binding protein | VF |
| RL465_RS24420 () | 152358..153055 | + | 698 | Protein_159 | IS1 family transposase | - |
| RL465_RS24425 () | 153235..153748 | - | 514 | Protein_160 | DUF4113 domain-containing protein | - |
| RL465_RS24430 () | 153809..153913 | - | 105 | Protein_161 | AAA family ATPase | - |
| RL465_RS24435 () | 153915..154238 | - | 324 | Protein_162 | IS21 family transposase IS21 | Transposase |
| RL465_RS24440 () | 154984..155961 | + | 978 | Protein_163 | RepB family plasmid replication initiator protein | - |
| RL465_RS24445 () | 156246..156985 | - | 740 | Protein_164 | site-specific integrase | - |
| RL465_RS24450 () | 157104..157174 | - | 71 | Protein_165 | serine/threonine protein kinase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|