MGE detailed information
MGE type: Conjugative plasmid MGE length: 130302 bp
Accession: NZ_LR883013 Location: 1..130302 Organism: Escherichia coli isolate L4_E1441_ETEC Replicon: plasmid 2
Accession: NZ_LR883013 Location: 1..130302 Organism: Escherichia coli isolate L4_E1441_ETEC Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JLZ95_RS23560 () | 1..978 | + | 978 | WP_074480756.1 | RepB family plasmid replication initiator protein | - |
| JLZ95_RS23565 () | 1221..1961 | - | 741 | WP_001066944.1 | tyrosine-type recombinase/integrase | - |
| JLZ95_RS23570 () | 2082..2210 | - | 129 | WP_032164396.1 | hypothetical protein | - |
| JLZ95_RS23575 () | 3161..3466 | + | 306 | WP_000336590.1 | Major pilu subunit operon regulatory protein PapB | VF |
| JLZ95_RS23580 () | 3718..4614 | + | 897 | WP_001695115.1 | transcriptional regulator HilD | - |
| JLZ95_RS23585 () | 4628..5071 | + | 444 | WP_001220546.1 | hypothetical protein | VF |
| JLZ95_RS23590 () | 5370..6080 | + | 711 | WP_113705914.1 | hypothetical protein | VF |
| JLZ95_RS23595 () | 6143..7714 | + | 1572 | WP_001759776.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | - |
| JLZ95_RS23600 () | 7733..8146 | + | 414 | WP_001201934.1 | TcpQ domain-containing protein | - |
| JLZ95_RS23605 () | 8164..9621 | + | 1458 | WP_000768353.1 | hypothetical protein | - |
| JLZ95_RS23610 () | 9624..10184 | + | 561 | WP_001047585.1 | hypothetical protein | - |
| JLZ95_RS23615 () | 10186..11013 | + | 828 | WP_001054274.1 | hypothetical protein | - |
| JLZ95_RS23620 () | 11001..11486 | + | 486 | WP_000336152.1 | hypothetical protein | - |
| JLZ95_RS23625 () | 11684..13018 | + | 1335 | WP_001380305.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| JLZ95_RS23630 () | 13002..14027 | + | 1026 | WP_001759772.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| JLZ95_RS23635 () | 14042..15163 | + | 1122 | WP_000857355.1 | hypothetical protein | - |
| JLZ95_RS23640 () | 15166..16020 | + | 855 | WP_000289148.1 | Type 4 prepilin-like proteins leader peptide-processing enzyme | VF |
| JLZ95_RS23645 () | 17039..18267 | + | 1229 | WP_088895425.1 | IS3 family transposase IS2 | Transposase |
| JLZ95_RS23650 () | 18470..18880 | - | 411 | Protein_18 | Tn3 family transposase ISEc63 | Transposase |
| JLZ95_RS23655 () | 19156..19736 | - | 581 | Protein_19 | IS3 family transposase IS2 | Transposase |
| JLZ95_RS23660 () | 19893..21074 | - | 1182 | WP_001467544.1 | DUF3800 domain-containing protein | - |
| JLZ95_RS23665 () | 21283..24249 | - | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| JLZ95_RS23670 () | 24252..24812 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| JLZ95_RS23675 () | 24938..25288 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| JLZ95_RS23680 () | 25491..26504 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| JLZ95_RS23685 () | 26661..27134 | + | 474 | WP_001355915.1 | IS1595 family transposase ISSsu9 | ARG |
| JLZ95_RS23690 () | 27236..28027 | + | 792 | WP_001206319.1 | Streptomycin 3''-adenylyltransferase | ARG |
| JLZ95_RS23695 () | 28191..28538 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| JLZ95_RS23700 () | 28532..29371 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| JLZ95_RS23705 () | 29499..29822 | + | 324 | Protein_29 | GNAT family N-acetyltransferase | - |
| JLZ95_RS23710 () | 29876..30988 | + | 1113 | WP_024179954.1 | IS4 family transposase IS421 | Transposase |
| JLZ95_RS23715 () | 31976..32218 | + | 243 | WP_000844627.1 | transposase | - |
| JLZ95_RS23720 () | 32250..32900 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| JLZ95_RS23725 () | 33006..34205 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| JLZ95_RS23730 () | 34237..35097 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| JLZ95_RS23735 () | 35106..35789 | - | 684 | Protein_35 | helix-turn-helix domain-containing protein | - |
| JLZ95_RS23740 () | 35864..36532 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| JLZ95_RS23745 () | 36568..36804 | - | 237 | WP_074480432.1 | broad-spectrum mercury transporter MerE | - |
| JLZ95_RS23750 () | 36801..37163 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| JLZ95_RS23755 () | 37181..38875 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| JLZ95_RS23760 () | 38927..39349 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| JLZ95_RS23765 () | 39385..39660 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| JLZ95_RS23770 () | 39674..40024 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| JLZ95_RS23775 () | 40096..40530 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| JLZ95_RS23780 () | 40636..41333 | - | 698 | Protein_44 | IS1 family transposase IS1R | Transposase |
| JLZ95_RS23785 () | 41448..41849 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JLZ95_RS23790 () | 41782..42039 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JLZ95_RS23795 () | 42132..42785 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JLZ95_RS23800 () | 43724..44581 | - | 858 | WP_074480778.1 | incFII family plasmid replication initiator RepA | - |
| JLZ95_RS23805 () | 44574..44648 | - | 75 | WP_011387702.1 | RepA leader peptide Tap | - |
| JLZ95_RS23810 () | 44882..45139 | - | 258 | WP_000083826.1 | replication regulatory protein RepA | - |
| JLZ95_RS23815 () | 45423..45629 | - | 207 | WP_001362723.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 45616..45677 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 45616..45677 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 45616..45677 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 45616..45677 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| JLZ95_RS23820 () | 45829..46293 | - | 465 | WP_001756974.1 | hypothetical protein | - |
| JLZ95_RS23825 () | 46448..47038 | - | 591 | WP_074480776.1 | DUF2726 domain-containing protein | - |
| JLZ95_RS23830 () | 47076..47285 | - | 210 | WP_001353639.1 | transcriptional regulator | - |
| JLZ95_RS23835 () | 47331..47792 | - | 462 | WP_001233850.1 | thermonuclease family protein | - |
| JLZ95_RS23840 () | 47848..48525 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| JLZ95_RS23845 () | 48525..48872 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| JLZ95_RS23850 () | 48892..50463 | + | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| JLZ95_RS23855 () | 50643..53273 | + | 2631 | WP_053916784.1 | type IV secretion system protein TraC | - |
| JLZ95_RS23860 () | 53270..53656 | + | 387 | WP_001399765.1 | type-F conjugative transfer system protein TrbI | - |
| JLZ95_RS23865 () | 53653..54285 | + | 633 | WP_074481277.1 | type-F conjugative transfer system protein TraW | - |
| JLZ95_RS23870 () | 54282..55274 | + | 993 | WP_000830836.1 | conjugal transfer pilus assembly protein TraU | - |
| JLZ95_RS23875 () | 55300..55608 | + | 309 | WP_000412445.1 | hypothetical protein | - |
| JLZ95_RS23880 () | 55778..56095 | + | 318 | Protein_64 | TraU family protein | - |
| JLZ95_RS23885 () | 56121..56582 | + | 462 | WP_000277848.1 | hypothetical protein | - |
| JLZ95_RS23890 () | 56612..57064 | + | 453 | WP_001732196.1 | hypothetical protein | - |
| JLZ95_RS23895 () | 57092..57181 | + | 90 | Protein_67 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| JLZ95_RS23900 () | 57273..57452 | + | 180 | WP_001750891.1 | hypothetical protein | - |
| JLZ95_RS23905 () | 57881..58519 | + | 639 | WP_001035183.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| JLZ95_RS23910 () | 58516..58887 | + | 372 | WP_000056341.1 | hypothetical protein | - |
| JLZ95_RS23915 () | 58912..59334 | + | 423 | WP_074481275.1 | HNH endonuclease | - |
| JLZ95_RS23920 () | 59331..61139 | + | 1809 | WP_074481274.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| JLZ95_RS23925 () | 61166..61423 | + | 258 | WP_001732201.1 | conjugal transfer protein TrbE | - |
| JLZ95_RS23930 () | 61416..62159 | + | 744 | WP_200997404.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| JLZ95_RS23935 () | 62284..62565 | + | 282 | WP_000549796.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JLZ95_RS23940 () | 62552..63097 | + | 546 | WP_000059698.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JLZ95_RS23945 () | 63027..63389 | + | 363 | WP_074481273.1 | P-type conjugative transfer protein TrbJ | - |
| JLZ95_RS23950 () | 63389..64762 | + | 1374 | WP_074481288.1 | conjugal transfer protein TraH | - |
| JLZ95_RS23955 () | 64759..67584 | + | 2826 | WP_074481272.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JLZ95_RS23960 () | 67581..68090 | + | 510 | WP_000628099.1 | conjugal transfer entry exclusion protein TraS | - |
| JLZ95_RS23965 () | 68104..68835 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| JLZ95_RS23970 () | 69038..69775 | + | 738 | WP_074481271.1 | hypothetical protein | - |
| JLZ95_RS23975 () | 69826..72087 | + | 2262 | WP_200997403.1 | type IV conjugative transfer system coupling protein TraD | - |
| JLZ95_RS23980 () | 72087..77357 | + | 5271 | WP_074481269.1 | Multifunctional conjugation protein TraI | Relaxase |
| JLZ95_RS23985 () | 77406..77825 | + | 420 | WP_000451342.1 | hypothetical protein | - |
| JLZ95_RS23990 () | 77847..78581 | + | 735 | WP_074481268.1 | conjugal transfer pilus acetylase TraX | - |
| JLZ95_RS23995 () | 78636..79196 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| JLZ95_RS24000 () | 79328..79540 | + | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| JLZ95_RS24005 () | 79821..81392 | - | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| JLZ95_RS24010 () | 81412..81759 | - | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| JLZ95_RS24015 () | 81759..82436 | - | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| JLZ95_RS24020 () | 82530..82766 | - | 237 | WP_000549576.1 | hypothetical protein | - |
| JLZ95_RS24025 () | 82759..82980 | - | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| JLZ95_RS24030 () | 83115..83630 | - | 516 | WP_074481278.1 | type IV conjugative transfer system lipoprotein TraV | - |
| JLZ95_RS24035 () | 83627..83878 | - | 252 | WP_074481279.1 | conjugal transfer protein TrbG | - |
| JLZ95_RS24040 () | 83871..84224 | - | 354 | WP_071594551.1 | conjugal transfer protein TrbD | - |
| JLZ95_RS24045 () | 84178..84744 | - | 567 | WP_044715774.1 | conjugal transfer protein TraP | - |
| JLZ95_RS24050 () | 84734..86185 | - | 1452 | WP_099558421.1 | conjugal transfer protein TraB | - |
| JLZ95_RS24055 () | 86185..86913 | - | 729 | WP_001230778.1 | type-F conjugative transfer system secretin TraK | - |
| JLZ95_RS24060 () | 86900..87466 | - | 567 | WP_000399801.1 | type IV conjugative transfer system protein TraE | - |
| JLZ95_RS24065 () | 87488..87799 | - | 312 | WP_000012116.1 | type IV conjugative transfer system protein TraL | - |
| JLZ95_RS24070 () | 87814..88179 | - | 366 | WP_001098999.1 | type IV conjugative transfer system pilin TraA | - |
| JLZ95_RS24075 () | 88211..88606 | - | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| JLZ95_RS24080 () | 88705..89394 | - | 690 | WP_000283390.1 | conjugal transfer transcriptional regulator TraJ | - |
| JLZ95_RS24085 () | 89581..89964 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| JLZ95_RS24090 () | 90286..90888 | + | 603 | WP_077631932.1 | hypothetical protein | VF |
| JLZ95_RS24095 () | 91185..92003 | - | 819 | WP_074481281.1 | DUF945 domain-containing protein | - |
| JLZ95_RS24100 () | 92114..92410 | - | 297 | WP_001272248.1 | hypothetical protein | - |
| JLZ95_RS24105 () | 93333..93494 | - | 162 | WP_000775238.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 93546..93746 | - | 201 | NuclAT_0 | - | Antitoxin Detail |
| - () | 93546..93746 | - | 201 | NuclAT_0 | - | Antitoxin Detail |
| - () | 93546..93746 | - | 201 | NuclAT_0 | - | Antitoxin Detail |
| - () | 93546..93746 | - | 201 | NuclAT_0 | - | Antitoxin Detail |
| JLZ95_RS24110 () | 93703..94017 | - | 315 | WP_000872086.1 | hypothetical protein | - |
| JLZ95_RS24115 () | 94014..94733 | - | 720 | WP_001276220.1 | plasmid SOS inhibition protein A | - |
| JLZ95_RS24120 () | 94730..95164 | - | 435 | WP_000845955.1 | conjugation system SOS inhibitor PsiB | - |
| JLZ95_RS24125 () | 95219..97183 | - | 1965 | WP_074481283.1 | ParB/RepB/Spo0J family partition protein | - |
| JLZ95_RS24130 () | 97244..97477 | - | 234 | WP_000005975.1 | DUF905 domain-containing protein | - |
| JLZ95_RS24135 () | 97534..98061 | - | 528 | WP_074481284.1 | single-stranded DNA-binding protein | - |
| JLZ95_RS24140 () | 98952..99515 | - | 564 | WP_001297832.1 | class I SAM-dependent methyltransferase | - |
| JLZ95_RS24145 () | 99562..100923 | - | 1362 | WP_000170686.1 | DUF3560 domain-containing protein | - |
| JLZ95_RS24150 () | 100975..101205 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| JLZ95_RS24155 () | 101720..102260 | + | 541 | Protein_119 | hypothetical protein | - |
| JLZ95_RS24160 () | 102239..102430 | - | 192 | WP_001024838.1 | hypothetical protein | - |
| JLZ95_RS24165 () | 102427..102849 | - | 423 | WP_000271732.1 | DUF1380 family protein | - |
| JLZ95_RS24170 () | 102896..103198 | - | 303 | WP_072105978.1 | antirestriction protein | - |
| JLZ95_RS24175 () | 103782..104894 | + | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| JLZ95_RS24180 () | 105084..105854 | - | 771 | WP_074481285.1 | hypothetical protein | - |
| JLZ95_RS24185 () | 105899..106333 | - | 435 | WP_074481286.1 | DUF1380 family protein | - |
| JLZ95_RS24190 () | 106347..106568 | - | 222 | WP_001104893.1 | hypothetical protein | - |
| JLZ95_RS24195 () | 106569..107252 | - | 684 | WP_074481287.1 | DNA methylase | - |
| JLZ95_RS24200 () | 107949..108965 | - | 1017 | WP_000219394.1 | IS110 family transposase ISShdy1 | Transposase |
| JLZ95_RS24205 () | 109303..110205 | - | 903 | WP_077899051.1 | DUF1281 domain-containing protein | - |
| JLZ95_RS24210 () | 110315..110605 | - | 291 | WP_074481295.1 | hypothetical protein | - |
| JLZ95_RS24215 () | 110629..111051 | - | 423 | WP_000774834.1 | plasmid partitioning/stability family protein | - |
| JLZ95_RS24220 () | 111054..112034 | - | 981 | WP_001218105.1 | plasmid segregation protein ParM | - |
| JLZ95_RS24225 () | 112237..112356 | + | 120 | Protein_133 | transposase domain-containing protein | - |
| JLZ95_RS24230 () | 112424..112990 | - | 567 | WP_024171032.1 | hypothetical protein | - |
| JLZ95_RS24235 () | 113638..114195 | + | 558 | WP_000103553.1 | hypothetical protein | VF |
| JLZ95_RS24240 () | 114504..114794 | + | 291 | WP_000754126.1 | DUF2282 domain-containing protein | - |
| JLZ95_RS24245 () | 114826..115752 | + | 927 | WP_000989040.1 | DUF692 domain-containing protein | - |
| JLZ95_RS24250 () | 115721..116479 | + | 759 | WP_001181584.1 | DNA-binding domain-containing protein | - |
| JLZ95_RS24255 () | 116481..117008 | + | 528 | WP_001196880.1 | DoxX family protein | - |
| JLZ95_RS24260 () | 117153..117299 | + | 147 | WP_001300272.1 | hypothetical protein | - |
| JLZ95_RS24265 () | 117341..117703 | - | 363 | WP_000181069.1 | hypothetical protein | - |
| JLZ95_RS24270 () | 117700..117828 | - | 129 | Protein_142 | DUF2164 family protein | - |
| JLZ95_RS24275 () | 118088..118189 | - | 102 | Protein_143 | methionyl-tRNA formyltransferase | - |
| JLZ95_RS24280 () | 118204..118713 | - | 510 | WP_000115001.1 | peptide deformylase | - |
| JLZ95_RS24285 () | 119037..120209 | + | 1173 | WP_000952428.1 | IS21 family transposase ISEc62 | Transposase |
| JLZ95_RS24290 () | 120209..121003 | + | 795 | WP_000544809.1 | IS21 family transposase ISEc62 | Transposase |
| JLZ95_RS24295 () | 121020..121505 | - | 486 | WP_074481298.1 | DUF1281 domain-containing protein | - |
| JLZ95_RS24300 () | 122090..123061 | - | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JLZ95_RS24305 () | 123061..124227 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| JLZ95_RS24310 () | 124760..125233 | - | 474 | Protein_150 | IS3 family transposase IS629 | Transposase |
| JLZ95_RS24315 () | 125323..126831 | - | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| JLZ95_RS24320 () | 127504..128243 | - | 740 | Protein_152 | IS3 family transposase IS1203 | Transposase |
| JLZ95_RS24325 () | 128304..129083 | + | 780 | Protein_153 | IS66 family transposase ISSgsp1 | Transposase |
| JLZ95_RS24330 () | 129227..129852 | - | 626 | Protein_154 | transposase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|