MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 170947 bp
Accession: NZ_LR882997 Location: 1333982..1504928 Organism: Escherichia coli isolate L3_E36_ETEC Replicon: chromosome
Accession: NZ_LR882997 Location: 1333982..1504928 Organism: Escherichia coli isolate L3_E36_ETEC Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JL022_RS06630 () | 1332126..1333424 | + | 1299 | WP_000841103.1 | alpha-ketoglutarate permease | - |
| JL022_RS06635 () | 1333421..1333744 | - | 324 | WP_001300818.1 | YfiM family lipoprotein | - |
| JL022_RS06640 () | 1333790..1335145 | - | 1356 | WP_000949265.1 | CDP-diacylglycerol--serine O-phosphatidyltransferase | - |
| JL022_RS06645 () | 1335259..1337919 | - | 2661 | WP_000082969.1 | protein lysine acetyltransferase | - |
| JL022_RS06650 () | 1337951..1338649 | - | 699 | WP_001343689.1 | tRNA-uridine aminocarboxypropyltransferase | - |
| JL022_RS06655 () | 1338718..1339137 | - | 420 | WP_001098726.1 | thioredoxin TrxC | - |
| JL022_RS06660 () | 1339344..1340381 | + | 1038 | WP_001760210.1 | tRNA/rRNA methyltransferase | - |
| JL022_RS06665 () | 1340429..1341118 | - | 690 | WP_001262723.1 | uracil-DNA glycosylase | - |
| JL022_RS06670 () | 1341423..1341806 | + | 384 | WP_000627807.1 | autonomous glycyl radical cofactor GrcA | - |
| JL022_RS06675 () | 1341861..1342448 | - | 588 | WP_000189206.1 | cysteine/O-acetylserine transporter | - |
| JL022_RS06680 () | 1342551..1343432 | + | 882 | WP_001297408.1 | LysR family transcriptional regulator | - |
| JL022_RS06685 () | 1343465..1344799 | - | 1335 | WP_001696609.1 | ATP-dependent RNA helicase SrmB | - |
| JL022_RS06690 () | 1344931..1345668 | + | 738 | WP_001297411.1 | tRNA(1)(Val) (adenine(37)-N(6))-methyltransferase TrmN | - |
| JL022_RS06695 () | 1345653..1347275 | - | 1623 | WP_001094498.1 | L-aspartate oxidase | - |
| JL022_RS06700 () | 1347531..1347686 | + | 156 | WP_001303621.1 | rpoE leader peptide RseD | - |
| JL022_RS06705 () | 1347683..1348258 | + | 576 | WP_001295364.1 | ECF RNA polymerase sigma-E factor | VF |
| JL022_RS06710 () | 1348291..1348941 | + | 651 | WP_001168459.1 | Anti-sigma-E factor RseA | VF |
| JL022_RS06715 () | 1348941..1349897 | + | 957 | WP_000812053.1 | Sigma-E factor regulatory protein RseB | VF |
| JL022_RS06720 () | 1349894..1350373 | + | 480 | WP_000589070.1 | Protein RseC | VF |
| JL022_RS06725 () | 1350571..1352370 | + | 1800 | WP_000790168.1 | translation elongation factor 4 | - |
| JL022_RS06730 () | 1352386..1353360 | + | 975 | WP_000002542.1 | signal peptidase I | - |
| JL022_RS06735 () | 1353632..1354312 | + | 681 | WP_001068343.1 | ribonuclease III | - |
| JL022_RS06740 () | 1354309..1355214 | + | 906 | WP_000020737.1 | GTPase Era | - |
| JL022_RS06745 () | 1355226..1355954 | + | 729 | WP_000399393.1 | DNA repair protein RecO | - |
| JL022_RS06750 () | 1355966..1356697 | + | 732 | WP_001297412.1 | Pyridoxine 5'-phosphate synthase | VF |
| JL022_RS06755 () | 1356697..1357077 | + | 381 | WP_000986029.1 | holo-ACP synthase | - |
| - () | 1357099..1357175 | - | 77 | NuclAT_12 | - | - |
| - () | 1357099..1357175 | - | 77 | NuclAT_12 | - | - |
| - () | 1357099..1357175 | - | 77 | NuclAT_12 | - | - |
| - () | 1357099..1357175 | - | 77 | NuclAT_12 | - | - |
| JL022_RS06760 () | 1357498..1357578 | + | 81 | WP_000128776.1 | type I toxin-antitoxin system toxin ShoB | - |
| JL022_RS06765 () | 1357772..1358032 | - | 261 | WP_001196283.1 | 4Fe-4S dicluster ferredoxin YfhL | - |
| JL022_RS06770 () | 1358088..1358936 | - | 849 | WP_001013779.1 | MurR/RpiR family transcriptional regulator | - |
| JL022_RS06775 () | 1359145..1359780 | + | 636 | WP_000190655.1 | phosphatidylglycerophosphatase C | - |
| JL022_RS06780 () | 1359805..1360341 | + | 537 | WP_001295367.1 | tRNA adenosine(34) deaminase TadA | - |
| JL022_RS06785 () | 1360338..1361894 | - | 1557 | WP_000734193.1 | membrane-bound lytic murein transglycosylase MltF | - |
| JL022_RS06790 () | 1362152..1366039 | + | 3888 | WP_000970115.1 | phosphoribosylformylglycinamidine synthase | - |
| JL022_RS06795 () | 1366615..1368042 | + | 1428 | WP_001297612.1 | two component system sensor histidine kinase QseE/GlrK | - |
| JL022_RS06800 () | 1368207..1368920 | + | 714 | WP_001215888.1 | two-component system QseEF-associated lipoprotein QseG | - |
| JL022_RS06805 () | 1368910..1370244 | + | 1335 | WP_001298983.1 | Transcriptional regulatory protein QseF | VF |
| JL022_RS06810 () | 1370305..1370643 | + | 339 | WP_000717694.1 | nitrogen regulatory protein P-II | - |
| JL022_RS06815 () | 1370688..1371878 | - | 1191 | WP_000883124.1 | NO-inducible flavohemoprotein | - |
| JL022_RS06820 () | 1372206..1373459 | + | 1254 | WP_000919159.1 | serine hydroxymethyltransferase | - |
| JL022_RS06825 () | 1373523..1374716 | - | 1194 | WP_001299519.1 | ROK family protein | - |
| JL022_RS06830 () | 1374834..1378115 | + | 3282 | WP_001388179.1 | DUF5107 domain-containing protein | - |
| JL022_RS06835 () | 1378212..1379195 | + | 984 | WP_001124907.1 | substrate-binding domain-containing protein | - |
| JL022_RS06840 () | 1379218..1380729 | + | 1512 | WP_001696600.1 | sugar ABC transporter ATP-binding protein | - |
| JL022_RS06845 () | 1380754..1381752 | + | 999 | WP_001276671.1 | ABC transporter permease | - |
| JL022_RS06850 () | 1381785..1382879 | + | 1095 | WP_000700800.1 | zinc-binding dehydrogenase | - |
| JL022_RS06855 () | 1382891..1383763 | + | 873 | WP_200995750.1 | aldose 1-epimerase | - |
| JL022_RS06860 () | 1383811..1384233 | - | 423 | WP_001094726.1 | DoxX family protein | - |
| JL022_RS06865 () | 1384330..1385532 | - | 1203 | WP_000660797.1 | phenylpropionate dioxygenase ferredoxin reductase subunit | - |
| JL022_RS06870 () | 1385542..1386354 | - | 813 | WP_001281377.1 | 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase | - |
| JL022_RS06875 () | 1386351..1386671 | - | 321 | WP_001080102.1 | bifunctional 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit | - |
| JL022_RS06880 () | 1386671..1387189 | - | 519 | WP_001276072.1 | 3-phenylpropionate/cinnamic acid dioxygenase subunit beta | - |
| JL022_RS06885 () | 1387186..1388547 | - | 1362 | WP_000211172.1 | aromatic ring-hydroxylating dioxygenase subunit alpha | - |
| JL022_RS06890 () | 1388683..1389573 | + | 891 | WP_000423257.1 | DNA-binding transcriptional regulator HcaR | - |
| JL022_RS06895 () | 1389733..1390872 | + | 1140 | WP_000244189.1 | 3-phenylpropionate MFS transporter | - |
| JL022_RS06900 () | 1390864..1392144 | - | 1281 | WP_000983009.1 | stationary phase inducible protein CsiE | - |
| JL022_RS06905 () | 1392335..1393189 | - | 855 | WP_001297705.1 | alpha/beta hydrolase | - |
| JL022_RS06910 () | 1393334..1394137 | - | 804 | WP_000553451.1 | inositol-1-monophosphatase | - |
| JL022_RS06915 () | 1394256..1394993 | + | 738 | WP_000940018.1 | tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ | - |
| JL022_RS06920 () | 1395294..1395782 | + | 489 | WP_001241357.1 | Fe-S cluster assembly transcriptional regulator IscR | - |
| JL022_RS06925 () | 1395894..1397108 | + | 1215 | WP_001295373.1 | cysteine desulfurase | - |
| JL022_RS06930 () | 1397136..1397522 | + | 387 | WP_000331707.1 | Fe-S cluster assembly scaffold IscU | - |
| JL022_RS06935 () | 1397539..1397862 | + | 324 | WP_000028953.1 | iron-sulfur cluster assembly protein IscA | - |
| JL022_RS06940 () | 1397958..1398473 | + | 516 | WP_000384411.1 | co-chaperone HscB | - |
| JL022_RS06945 () | 1398490..1400340 | + | 1851 | WP_001196613.1 | Fe-S protein assembly chaperone HscA | - |
| JL022_RS06950 () | 1400342..1400677 | + | 336 | WP_001124469.1 | ISC system 2Fe-2S type ferredoxin | - |
| JL022_RS06955 () | 1400689..1400889 | + | 201 | WP_000523616.1 | Fe-S cluster assembly protein IscX | - |
| JL022_RS06960 () | 1400948..1402231 | + | 1284 | WP_000133608.1 | aminopeptidase PepB | - |
| JL022_RS06965 () | 1402373..1403149 | + | 777 | WP_001297328.1 | enhanced serine sensitivity protein SseB | - |
| JL022_RS06970 () | 1403642..1404487 | - | 846 | WP_000108626.1 | 3-mercaptopyruvate sulfurtransferase | - |
| JL022_RS06975 () | 1404694..1409655 | + | 4962 | WP_001696560.1 | alpha2-macroglobulin | - |
| JL022_RS06980 () | 1409656..1411968 | + | 2313 | WP_001137684.1 | peptidoglycan glycosyltransferase PbpC | - |
| JL022_RS06985 () | 1412117..1412548 | + | 432 | WP_001696558.1 | nucleoside-diphosphate kinase | - |
| JL022_RS06990 () | 1412698..1413852 | + | 1155 | WP_000003317.1 | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | - |
| JL022_RS06995 () | 1414137..1415150 | + | 1014 | WP_001090844.1 | cytoskeleton protein RodZ | - |
| JL022_RS07000 () | 1415177..1416295 | + | 1119 | WP_000551820.1 | flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase | - |
| JL022_RS07005 () | 1416406..1417680 | + | 1275 | WP_001107180.1 | histidine--tRNA ligase | - |
| JL022_RS07010 () | 1417698..1418318 | + | 621 | WP_000409205.1 | ancillary SecYEG translocon subunit YfgM | - |
| JL022_RS07015 () | 1418329..1419507 | + | 1179 | WP_001177043.1 | outer membrane protein assembly factor BamB | - |
| JL022_RS07020 () | 1419625..1421097 | + | 1473 | WP_000249410.1 | ribosome biogenesis GTPase Der | - |
| JL022_RS07025 () | 1421166..1421381 | + | 216 | WP_001297332.1 | zinc ribbon domain-containing protein | - |
| JL022_RS07030 () | 1421378..1422748 | - | 1371 | WP_000937933.1 | exodeoxyribonuclease VII large subunit | - |
| JL022_RS07035 () | 1422910..1424376 | + | 1467 | WP_001299507.1 | IMP dehydrogenase | - |
| JL022_RS07040 () | 1424445..1426022 | + | 1578 | WP_000138282.1 | glutamine-hydrolyzing GMP synthase | - |
| JL022_RS07045 () | 1426331..1427518 | + | 1188 | WP_001696555.1 | Prophage integrase IntA ; Integrase | Integrase |
| JL022_RS07050 () | 1427567..1429528 | + | 1962 | WP_000687641.1 | AAA family ATPase | - |
| JL022_RS07055 () | 1429525..1431390 | + | 1866 | WP_000199052.1 | ATP-dependent helicase | - |
| JL022_RS07060 () | 1431514..1432161 | - | 648 | Protein_1381 | LuxR family transcriptional regulator | - |
| JL022_RS07065 () | 1432233..1433380 | + | 1148 | WP_085949154.1 | IS3 family transposase ISEc52 | Transposase |
| JL022_RS07070 () | 1433906..1434127 | + | 222 | WP_024168710.1 | AlpA family phage regulatory protein | - |
| JL022_RS07075 () | 1434132..1434995 | + | 864 | WP_001162383.1 | helicase RepA family protein | - |
| JL022_RS07080 () | 1434982..1435737 | + | 756 | WP_000206936.1 | hypothetical protein | - |
| JL022_RS07085 () | 1436856..1437632 | + | 777 | WP_001174503.1 | P-type conjugative transfer protein TrbJ | - |
| JL022_RS07090 () | 1437635..1437832 | + | 198 | WP_000790452.1 | hypothetical protein | - |
| JL022_RS07095 () | 1437835..1439130 | + | 1296 | WP_001409911.1 | P-type conjugative transfer protein TrbL | - |
| JL022_RS07100 () | 1439186..1439383 | + | 198 | WP_001076796.1 | hypothetical protein | - |
| JL022_RS07105 () | 1439404..1439658 | + | 255 | WP_000395519.1 | hypothetical protein | - |
| JL022_RS07110 () | 1439731..1439973 | + | 243 | WP_000213950.1 | type I toxin-antitoxin system ptaRNA1 family toxin | - |
| JL022_RS07115 () | 1440006..1441700 | - | 1695 | WP_001696538.1 | hypothetical protein | - |
| JL022_RS07120 () | 1442232..1442771 | - | 540 | WP_000755179.1 | DUF5384 family protein | - |
| JL022_RS07125 () | 1442787..1443305 | - | 519 | WP_001295476.1 | glycine zipper 2TM domain-containing protein | - |
| JL022_RS07130 () | 1443616..1443807 | - | 192 | WP_000076001.1 | DUF2633 family protein | - |
| JL022_RS07135 () | 1443825..1443977 | + | 153 | WP_000017552.1 | hypothetical protein | - |
| JL022_RS07140 () | 1444159..1446402 | + | 2244 | WP_000772726.1 | Cyclic di-GMP phosphodiesterase PdeF | VF |
| JL022_RS07145 () | 1446441..1447982 | - | 1542 | WP_001121363.1 | exopolyphosphatase | - |
| JL022_RS07150 () | 1447987..1450053 | - | 2067 | WP_000529576.1 | polyphosphate kinase 1 | - |
| JL022_RS07155 () | 1450224..1450862 | - | 639 | WP_001028614.1 | phosphoribosylglycinamide formyltransferase | - |
| JL022_RS07160 () | 1450862..1451899 | - | 1038 | WP_001295474.1 | Phosphoribosylformylglycinamidine cyclo-ligase | VF |
| JL022_RS07165 () | 1452224..1452850 | + | 627 | WP_001295473.1 | uracil phosphoribosyltransferase | - |
| JL022_RS07170 () | 1452936..1454225 | + | 1290 | WP_000198328.1 | uracil permease | - |
| JL022_RS07175 () | 1454275..1455021 | + | 747 | WP_000247065.1 | DnaA inactivator Hda | - |
| JL022_RS07180 () | 1455159..1455518 | - | 360 | WP_000166467.1 | arsenate reductase (glutaredoxin) | - |
| JL022_RS07185 () | 1455539..1457002 | - | 1464 | WP_000489667.1 | beta-barrel assembly-enhancing protease | - |
| JL022_RS07190 () | 1457215..1458276 | + | 1062 | WP_000892044.1 | AI-2E family transporter | - |
| JL022_RS07195 () | 1458314..1459162 | - | 849 | WP_001244724.1 | formate transporter | - |
| JL022_RS07200 () | 1459184..1461196 | - | 2013 | WP_001251569.1 | DNA-binding transcriptional activator HyfR | VF |
| JL022_RS07205 () | 1461226..1461639 | - | 414 | WP_000133936.1 | hydrogenase 4 assembly chaperone HyfJ | - |
| JL022_RS07210 () | 1461632..1462390 | - | 759 | WP_000075569.1 | hydrogenase 4 catalytic subunit HyfI | - |
| JL022_RS07215 () | 1462387..1462932 | - | 546 | WP_000916058.1 | hydrogenase 4 subunit H | - |
| JL022_RS07220 () | 1462942..1464609 | - | 1668 | WP_001102276.1 | hydrogenase 4 catalytic subunit HyfG | - |
| JL022_RS07225 () | 1464599..1466180 | - | 1582 | Protein_1414 | hydrogenase 4 subunit F | - |
| JL022_RS07230 () | 1466185..1466835 | - | 651 | WP_000147987.1 | hydrogenase 4 membrane subunit | - |
| JL022_RS07235 () | 1466847..1468078 | - | 1232 | Protein_1416 | hydrogenase 4 subunit D | - |
| JL022_RS07240 () | 1468095..1469042 | - | 948 | WP_001317255.1 | hydrogenase 4 subunit HyfC | - |
| JL022_RS07245 () | 1469053..1471070 | - | 2018 | Protein_1418 | hydrogenase 4 subunit B | - |
| JL022_RS07250 () | 1471070..1471687 | - | 618 | WP_001299064.1 | hydrogenase 4 subunit HyfA | - |
| JL022_RS07255 () | 1471940..1472410 | - | 471 | WP_001068682.1 | thioredoxin-dependent thiol peroxidase | - |
| JL022_RS07260 () | 1472410..1472982 | - | 573 | WP_000176187.1 | glycine cleavage system transcriptional repressor | - |
| JL022_RS07265 () | 1473128..1474006 | + | 879 | WP_001295469.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| JL022_RS07270 () | 1474023..1475057 | + | 1035 | WP_001297320.1 | outer membrane protein assembly factor BamC | - |
| JL022_RS07275 () | 1475270..1475983 | + | 714 | WP_200995751.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| JL022_RS07280 () | 1476138..1476365 | + | 228 | WP_001696518.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| JL022_RS07285 () | 1476365..1476763 | + | 399 | WP_000911329.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| JL022_RS07290 () | 1476910..1477773 | + | 864 | WP_001267498.1 | neutral zinc metallopeptidase | - |
| JL022_RS07295 () | 1477788..1479803 | + | 2016 | WP_001388162.1 | tRNA cytosine(34) acetyltransferase TmcA | - |
| JL022_RS07300 () | 1479877..1480575 | + | 699 | WP_000679812.1 | esterase | - |
| JL022_RS07305 () | 1480656..1480856 | - | 201 | WP_000383836.1 | YpfN family protein | - |
| JL022_RS07310 () | 1480884..1482011 | - | 1128 | WP_001277801.1 | succinyl-diaminopimelate desuccinylase | - |
| JL022_RS07315 () | 1482015..1482371 | - | 357 | WP_000258247.1 | ArsC family reductase | - |
| JL022_RS07320 () | 1482752..1482811 | + | 60 | WP_001386977.1 | protein YpfM | - |
| JL022_RS07325 () | 1482910..1486023 | - | 3114 | WP_001760194.1 | Multidrug efflux pump subunit AcrB | VF |
| JL022_RS07330 () | 1486187..1487887 | - | 1701 | WP_000636129.1 | nitrate/nitrite two-component system sensor histidine kinase NarQ | - |
| JL022_RS07335 () | 1488093..1490072 | + | 1980 | WP_001078871.1 | formate-dependent uric acid utilization protein AegA | - |
| JL022_RS07340 () | 1490140..1490715 | + | 576 | WP_000193711.1 | GDP-mannose pyrophosphatase NudK | - |
| JL022_RS07345 () | 1490841..1491884 | + | 1044 | WP_001270528.1 | DUF1176 domain-containing protein | - |
| JL022_RS07350 () | 1491980..1493983 | - | 2004 | WP_000087280.1 | transketolase | - |
| JL022_RS07355 () | 1494003..1494953 | - | 951 | WP_001003709.1 | transaldolase | - |
| JL022_RS07360 () | 1495242..1497521 | + | 2280 | WP_000342642.1 | NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase | - |
| JL022_RS07365 () | 1497814..1498149 | + | 336 | WP_000356956.1 | ethanolamine utilization microcompartment protein EutS | - |
| JL022_RS07370 () | 1498162..1498641 | + | 480 | WP_000820764.1 | ethanolamine utilization acetate kinase EutP | - |
| JL022_RS07375 () | 1498616..1499317 | + | 702 | WP_000733903.1 | ethanolamine utilization acetate kinase EutQ | - |
| JL022_RS07380 () | 1499314..1500117 | + | 804 | WP_000651298.1 | ethanolamine utilization cob(I)yrinic acid a,c-diamide adenosyltransferase EutT | - |
| JL022_RS07385 () | 1500114..1501130 | + | 1017 | WP_000582977.1 | phosphate acetyltransferase | - |
| JL022_RS07390 () | 1501169..1501462 | + | 294 | WP_000387713.1 | ethanolamine utilization microcompartment protein EutM | - |
| JL022_RS07395 () | 1501569..1501856 | + | 288 | WP_000762196.1 | ethanolamine utilization microcompartment protein EutN | - |
| JL022_RS07400 () | 1501868..1503271 | + | 1404 | WP_001075711.1 | Gamma-glutamyl phosphate reductase | VF |
| JL022_RS07405 () | 1503282..1504118 | + | 837 | WP_000929729.1 | ethanolamine utilization protein EutJ | - |
| JL022_RS07410 () | 1504108..1505295 | + | 1188 | WP_001315777.1 | ethanolamine utilization ethanol dehydrogenase EutG | - |
| JL022_RS07415 () | 1505412..1506638 | + | 1227 | WP_000512372.1 | ethanolamine utilization protein EutH | - |
| JL022_RS07420 () | 1506635..1508038 | + | 1404 | WP_001097478.1 | ethanolamine ammonia-lyase reactivating factor EutA | - |
| JL022_RS07425 () | 1508050..1509411 | + | 1362 | WP_000769961.1 | ethanolamine ammonia-lyase subunit alpha | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|