NZ_LR5364304777456..4972255

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 194800 bp
Accession: NZ_LR536430        Location: 4777456..4972255         Organism: Escherichia coli isolate f974b26a-5e81-11e8-bf7f-3c4a9275d6c8       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4Z69_RS23485 () 4772665..4773597 + 933 WP_001319943.1 D-alanyl-D-alanine endopeptidase -
E4Z69_RS23490 () 4773636..4775351 - 1716 WP_000097374.1 D-lactate dehydrogenase -
E4Z69_RS23495 () 4775547..4777844 + 2298 WP_000871509.1 beta-glucosidase BglX -
E4Z69_RS23500 () 4778096..4779013 + 918 WP_001131253.1 glycine betaine ABC transporter substrate-binding protein OsmF -
E4Z69_RS23505 () 4779020..4780177 + 1158 WP_101361033.1 glycine betaine ABC transporter permease YehY -
E4Z69_RS23510 () 4780170..4781096 + 927 WP_000569358.1 Glycine betaine uptake system ATP-binding protein YehX VF
E4Z69_RS23515 () 4781101..4781832 + 732 WP_000783120.1 glycine betaine ABC transporter permease YehW -
E4Z69_RS23520 () 4781813..4781920 - 108 WP_001216963.1 protein YohO -
E4Z69_RS23525 () 4781980..4782711 - 732 WP_097435899.1 HTH-type transcriptional regulator MlrA -
E4Z69_RS23530 () 4782933..4784618 + 1686 WP_001445970.1 Sensor histidine kinase BtsS VF
E4Z69_RS23535 () 4784615..4785334 + 720 WP_000598641.1 two-component system response regulator BtsR -
E4Z69_RS23540 () 4785381..4785851 + 471 WP_134393484.1 DUF1456 family protein -
E4Z69_RS23545 () 4785891..4786352 - 462 WP_001445971.1 YehR family lipoprotein -
E4Z69_RS23550 () 4786477..4788477 - 2001 WP_001370558.1 SWIM zinc finger family protein -
E4Z69_RS23555 () 4788474..4789610 - 1137 WP_001292766.1 VWA domain-containing protein -
E4Z69_RS23560 () 4789603..4791882 - 2280 WP_101361032.1 hypothetical protein -
E4Z69_RS23565 () 4791893..4792981 - 1089 WP_000074859.1 MoxR family ATPase -
E4Z69_RS23570 () 4793287..4793604 - 318 WP_000636939.1 hypothetical protein -
E4Z69_RS23575 () 4793666..4797298 - 3633 WP_016240117.1 DUF4132 domain-containing protein -
E4Z69_RS23580 () 4797308..4801102 - 3795 WP_001215603.1 WGR and DUF4132 domain-containing protein -
E4Z69_RS23585 () 4801243..4803276 - 2034 WP_001295427.1 methionine--tRNA ligase -
E4Z69_RS23590 () 4803408..4804517 + 1110 WP_001005448.1 iron-sulfur cluster carrier protein ApbC -
E4Z69_RS23595 () 4804780..4805061 + 282 WP_001324851.1 YehE family protein -
E4Z69_RS23600 () 4805353..4805895 + 543 WP_000830468.1 fimbrial protein -
E4Z69_RS23605 () 4805975..4806496 + 522 Protein_4561 putative fimbrial chaperone YehC VF
E4Z69_RS23610 () 4806512..4807209 - 698 Protein_4562 IS1 family transposase IS1R Transposase
E4Z69_RS23615 () 4807315..4807425 + 111 WP_016241359.1 hypothetical protein -
E4Z69_RS23620 () 4807441..4809198 + 1758 Protein_4564 Outer membrane usher protein YehB VF
E4Z69_RS23630 () 4809234..4809536 + 303 Protein_4565 IS3 family transposase ISEc31 Transposase
E4Z69_RS23635 () 4809549..4810700 - 1152 WP_001254932.1 IS30 family transposase IS30D Transposase
E4Z69_RS23645 () 4810765..4811190 + 426 Protein_4567 IS3 family transposase -
E4Z69_RS23655 () 4811863..4813371 + 1509 WP_134393492.1 group II intron reverse transcriptase/maturase -
E4Z69_RS23660 () 4813452..4813631 + 180 Protein_4569 IS3 family transposase -
E4Z69_RS23670 () 4813913..4814989 + 1077 WP_000227970.1 IS110 family transposase ISEc21 Transposase
E4Z69_RS23675 () 4815006..4815314 + 309 Protein_4571 IS3 family transposase ISEc31 Transposase
E4Z69_RS23680 () 4815324..4816049 + 726 Protein_4572 fimbria/pilus outer membrane usher protein -
E4Z69_RS23685 () 4816065..4817099 + 1035 WP_016240113.1 putative fimbrial-like adhesin protein -
E4Z69_RS23690 () 4817181..4817519 - 339 WP_000153067.1 Ni(II)/Co(II) efflux transporter accessory subunit RcnB -
E4Z69_RS23695 () 4817738..4818562 - 825 WP_016240112.1 nickel/cobalt efflux protein RcnA -
E4Z69_RS23700 () 4818683..4818955 + 273 WP_000019944.1 Ni(II)/Co(II)-binding transcriptional repressor RcnR -
E4Z69_RS23705 () 4819210..4819752 + 543 Protein_4577 integrase -
E4Z69_RS23710 () 4819819..4820981 + 1163 WP_085947598.1 IS3 family transposase ISEc17 Transposase
E4Z69_RS23715 () 4821422..4822210 + 789 WP_001195589.1 hydroxyethylthiazole kinase -
E4Z69_RS23720 () 4822207..4823007 + 801 WP_000822274.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
E4Z69_RS23725 () 4823072..4823890 + 819 WP_001351455.1 glycoside hydrolase family 25 protein -
E4Z69_RS23730 () 4823942..4824688 + 747 WP_000434038.1 GntR family transcriptional regulator -
E4Z69_RS23735 () 4824662..4825627 - 966 Protein_4583 sugar kinase -
E4Z69_RS23740 () 4825624..4826628 - 1005 WP_000846245.1 ADP-ribosylglycohydrolase family protein -
E4Z69_RS23745 () 4826625..4827902 - 1278 WP_000858484.1 nucleoside permease -
E4Z69_RS23750 () 4828159..4829211 + 1053 WP_000129551.1 class I fructose-bisphosphate aldolase -
E4Z69_RS23755 () 4829519..4830373 + 855 WP_000289788.1 tagatose-bisphosphate aldolase subunit GatY -
E4Z69_RS23760 () 4830402..4831664 + 1263 WP_000853883.1 tagatose-bisphosphate aldolase subunit GatZ -
E4Z69_RS23765 () 4831674..4832126 + 453 WP_000182904.1 PTS galactitol transporter subunit IIA -
E4Z69_RS23770 () 4832157..4832441 + 285 WP_000823272.1 PTS galactitol transporter subunit IIB -
E4Z69_RS23775 () 4832445..4833800 + 1356 WP_000490675.1 galactitol-specific PTS transporter subunit IIC -
E4Z69_RS23780 () 4833848..4834888 + 1041 WP_000844219.1 galactitol-1-phosphate 5-dehydrogenase -
E4Z69_RS23785 () 4834994..4835767 + 774 WP_197731752.1 DeoR/GlpR family DNA-binding transcription regulator -
E4Z69_RS23790 () 4835849..4836748 - 900 WP_000807373.1 lipid kinase YegS -
E4Z69_RS23795 () 4837154..4837471 + 318 WP_001295425.1 hypothetical protein -
E4Z69_RS23805 () 4837662..4838993 - 1332 WP_043015601.1 IS4 family transposase ISCro6 Transposase
E4Z69_RS23810 () 4839244..4840605 - 1362 WP_000476011.1 tRNA 5-hydroxyuridine modification protein YegQ -
E4Z69_RS23815 () 4840708..4841004 - 297 WP_001220181.1 type II toxin-antitoxin system RelE/ParE family toxin -
E4Z69_RS23820 () 4841006..4841302 - 297 WP_001307279.1 type II toxin-antitoxin system ParD family antitoxin -
E4Z69_RS23825 () 4841511..4841843 - 333 WP_000929408.1 YegP family protein -
E4Z69_RS23830 () 4842034..4842756 - 723 WP_000137841.1 Transcriptional regulatory protein BaeR VF
E4Z69_RS23835 () 4842753..4844157 - 1405 Protein_4602 two-component system sensor histidine kinase BaeS -
E4Z69_RS23840 () 4844154..4845569 - 1416 WP_000130843.1 MFS transporter -
E4Z69_RS23845 () 4845570..4848647 - 3078 WP_032175502.1 multidrug efflux RND transporter permease subunit MdtC -
E4Z69_RS23850 () 4848648..4851770 - 3123 WP_001197875.1 Multidrug resistance protein MdtB VF
E4Z69_RS23855 () 4851770..4853017 - 1248 WP_000678954.1 Multidrug resistance protein MdtA VF
- () 4853254..4853389 - 136 NuclAT_8 - -
- () 4853254..4853389 - 136 NuclAT_8 - -
- () 4853254..4853389 - 136 NuclAT_8 - -
- () 4853254..4853389 - 136 NuclAT_8 - -
E4Z69_RS23860 () 4853296..4853352 + 57 WP_012767741.1 type I toxin-antitoxin system Ibs family toxin -
- () 4853582..4853724 - 143 NuclAT_6 - -
- () 4853582..4853724 - 143 NuclAT_6 - -
- () 4853582..4853724 - 143 NuclAT_6 - -
- () 4853582..4853724 - 143 NuclAT_6 - -
E4Z69_RS23865 () 4853625..4853684 + 60 WP_010723109.1 type I toxin-antitoxin system toxin IbsA -
E4Z69_RS23870 () 4853905..4854564 + 660 WP_000003200.1 VWA domain-containing protein -
E4Z69_RS23875 () 4854561..4855322 + 762 WP_032295989.1 protein phosphatase 2C domain-containing protein -
E4Z69_RS23880 () 4855319..4857259 + 1941 WP_032175500.1 protein kinase YegI -
E4Z69_RS23885 () 4857272..4858624 - 1353 WP_032175499.1 molecular chaperone -
E4Z69_RS23890 () 4858758..4859610 + 853 Protein_4613 DNA-3-methyladenine glycosylase 2 -
E4Z69_RS23895 () 4859649..4862966 - 3318 WP_032175498.1 diguanylate cyclase -
E4Z69_RS23900 () 4863284..4863925 + 642 WP_001295424.1 uridine kinase -
E4Z69_RS23905 () 4864017..4864598 + 582 WP_001234767.1 dCTP deaminase -
E4Z69_RS23910 () 4864620..4866473 + 1854 WP_001252331.1 outer membrane assembly protein AsmA -
E4Z69_RS23915 () 4866747..4868330 - 1584 WP_000454701.1 TerC family protein -
E4Z69_RS23920 () 4868989..4870128 + 1140 WP_000978094.1 hypothetical protein VF
E4Z69_RS23925 () 4870134..4870577 + 444 WP_000482901.1 Low molecular weight protein-tyrosine-phosphatase Wzb VF
E4Z69_RS23930 () 4870580..4872742 + 2163 WP_000137196.1 Tyrosine-protein kinase wzc VF
E4Z69_RS23935 () 4872835..4873674 + 840 WP_000654491.1 hypothetical protein VF
E4Z69_RS23940 () 4873677..4874165 + 489 WP_000888729.1 Serine acetyltransferase VF
E4Z69_RS23945 () 4874162..4875379 + 1218 WP_001023946.1 hypothetical protein VF
E4Z69_RS23950 () 4875354..4876571 + 1218 WP_001549393.1 putative colanic acid polymerase WcaD -
E4Z69_RS23955 () 4876661..4877641 + 981 WP_016240301.1 IS5 family transposase IS5D Transposase
E4Z69_RS23960 () 4877775..4878527 + 753 WP_134393486.1 colanic acid biosynthesis glycosyltransferase WcaE -
E4Z69_RS23965 () 4878543..4879091 + 549 WP_001153573.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase VF
E4Z69_RS23970 () 4879117..4880238 + 1122 WP_000048190.1 GDP-mannose 4,6-dehydratase VF
E4Z69_RS23975 () 4880241..4881206 + 966 WP_000043606.1 GDP-L-fucose synthase VF
E4Z69_RS23980 () 4881209..4881688 + 480 WP_001309580.1 GDP-mannose mannosyl hydrolase VF
E4Z69_RS23985 () 4881685..4882908 + 1224 WP_101360997.1 hypothetical protein VF
E4Z69_RS23990 () 4882911..4884356 + 1446 WP_101360998.1 Mannose-1-phosphate guanylyltransferase 1 VF
E4Z69_RS23995 () 4884549..4885919 + 1371 WP_134393487.1 Phosphomannomutase/phosphoglucomutase VF
E4Z69_RS24000 () 4885974..4887368 + 1395 WP_101361095.1 UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase VF
E4Z69_RS24005 () 4887370..4888848 + 1479 WP_101361094.1 colanic acid undecaprenyl disphosphate flippase WzxC -
E4Z69_RS24010 () 4889132..4890412 + 1281 WP_101361093.1 colanic acid biosynthesis pyruvyl transferase WcaK -
E4Z69_RS24015 () 4890409..4891629 + 1221 WP_001507571.1 colanic acid biosynthesis glycosyltransferase WcaL -
E4Z69_RS24020 () 4891640..4893034 + 1395 WP_101361092.1 colanic acid biosynthesis protein WcaM -
E4Z69_RS24025 () 4893192..4894187 + 996 WP_000999466.1 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans, octacis-undecaprenol 4-epimerase -
E4Z69_RS24030 () 4894430..4895323 + 894 WP_000183060.1 UTP--glucose-1-phosphate uridylyltransferase VF
E4Z69_RS24035 () 4895696..4896931 + 1236 WP_000916633.1 O11 family O-antigen flippase -
E4Z69_RS24040 () 4896940..4897665 + 726 WP_001322701.1 hypothetical protein VF
E4Z69_RS24045 () 4897662..4898897 + 1236 WP_101361091.1 O11 family O-antigen polymerase -
E4Z69_RS24050 () 4898899..4899966 + 1068 WP_101361090.1 glycosyltransferase -
E4Z69_RS24055 () 4899987..4901003 + 1017 WP_101361089.1 UDP-glucose 4-epimerase VF
E4Z69_RS24060 () 4901072..4902079 + 1008 WP_119877218.1 D-inositol-3-phosphate glycosyltransferase VF
E4Z69_RS24065 () 4902090..4903211 + 1122 WP_000335121.1 GDP-mannose 4,6-dehydratase VF
E4Z69_RS24070 () 4903215..4904180 + 966 WP_000163129.1 GDP-L-fucose synthase VF
E4Z69_RS24075 () 4904183..4904638 + 456 WP_101361088.1 GDP-mannose mannosyl hydrolase VF
E4Z69_RS24080 () 4904650..4906035 + 1386 WP_001361571.1 Mannose-1-phosphate guanylyltransferase 1 VF
E4Z69_RS24085 () 4906119..4906865 + 747 WP_000868617.1 PGL/p-HBAD biosynthesis glycosyltransferase VF
E4Z69_RS24090 () 4906890..4908260 + 1371 WP_134393488.1 Phosphomannomutase/phosphoglucomutase VF
E4Z69_RS24095 () 4908424..4909830 + 1407 WP_101361076.1 6-phosphogluconate dehydrogenase, decarboxylating VF
E4Z69_RS24100 () 4910080..4911246 + 1167 WP_000704873.1 UDP-glucose 6-dehydrogenase VF
E4Z69_RS24105 () 4911392..4912369 + 978 WP_001556091.1 LPS O-antigen chain length determinant protein WzzB -
E4Z69_RS24115 () 4912466..4913077 - 612 WP_000954919.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE -
E4Z69_RS24120 () 4913071..4913847 - 777 WP_072804417.1 imidazole glycerol phosphate synthase subunit HisF -
E4Z69_RS24125 () 4913829..4914566 - 738 WP_101361078.1 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase -
E4Z69_RS24130 () 4914566..4915156 - 591 WP_001103560.1 imidazole glycerol phosphate synthase subunit HisH -
E4Z69_RS24135 () 4915156..4916223 - 1068 WP_000080136.1 Histidine biosynthesis bifunctional protein HisB VF
E4Z69_RS24140 () 4916223..4917293 - 1071 WP_000108941.1 histidinol-phosphate transaminase -
E4Z69_RS24145 () 4917296..4918594 - 1299 WP_063074566.1 histidinol dehydrogenase -
E4Z69_RS24150 () 4918600..4919499 - 900 WP_000131782.1 ATP phosphoribosyltransferase -
E4Z69_RS24155 () 4919645..4919695 - 51 WP_001364200.1 his operon leader peptide -
E4Z69_RS24160 () 4919978..4920229 + 252 WP_001259255.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin Detail
E4Z69_RS24165 () 4920226..4920480 + 255 WP_000767829.1 type II toxin-antitoxin system mRNA interferase toxin YoeB Toxin Detail
E4Z69_RS24170 () 4920563..4921387 + 825 WP_000754762.1 SDR family oxidoreductase -
E4Z69_RS24175 () 4921433..4922362 + 930 WP_000803360.1 LysR family transcriptional regulator -
E4Z69_RS24180 () 4922577..4922639 + 63 WP_010723108.1 membrane protein YoeI -
E4Z69_RS24185 () 4922629..4923987 + 1359 WP_077483161.1 putrescine/proton symporter PlaP -
E4Z69_RS24190 () 4924166..4925224 + 1059 WP_000492305.1 transport protein YeeE -
E4Z69_RS24195 () 4925238..4925465 + 228 WP_000985273.1 sulfurtransferase TusA family protein -
E4Z69_RS24200 () 4925508..4926935 - 1428 WP_000980601.1 exodeoxyribonuclease I -
E4Z69_RS24205 () 4927144..4928310 + 1167 WP_000830156.1 serine-type D-Ala-D-Ala carboxypeptidase DacD -
E4Z69_RS24210 () 4928429..4928902 + 474 WP_016246080.1 DNA gyrase inhibitor SbmC -
E4Z69_RS24215 () 4929101..4930159 + 1059 WP_001200892.1 FUSC family protein -
E4Z69_RS24220 () 4930331..4930660 + 330 WP_000450409.1 DUF496 family protein -
E4Z69_RS24225 () 4930835..4933348 - 2514 Protein_4679 Ag43/Cah family autotransporter adhesin -
E4Z69_RS24235 () 4933698..4934207 - 510 WP_077641567.1 hypothetical protein -
E4Z69_RS24240 () 4934272..4934559 - 288 Protein_4681 DDE-type integrase/transposase/recombinase -
E4Z69_RS24245 () 4934576..4935652 - 1077 WP_000227970.1 IS110 family transposase ISEc21 Transposase
E4Z69_RS24250 () 4935938..4936321 + 384 WP_001201739.1 IS66 family transposase IS682 Transposase
E4Z69_RS24255 () 4936318..4936665 + 348 WP_000609174.1 IS66 family transposase ISCfr14 Transposase
E4Z69_RS24260 () 4936715..4938250 + 1536 WP_001000406.1 IS66 family transposase ISSgsp1 Transposase
E4Z69_RS24265 () 4938340..4938504 - 165 Protein_4686 IS3 family transposase -
E4Z69_RS24270 () 4938639..4940147 - 1509 WP_001189111.1 group II intron reverse transcriptase/maturase -
E4Z69_RS24280 () 4940820..4941245 - 426 Protein_4688 IS3 family transposase -
E4Z69_RS24285 () 4941255..4942406 - 1152 WP_001254932.1 IS30 family transposase IS30D Transposase
E4Z69_RS24595 () 4942474..4942731 - 258 Protein_4690 IS3 family transposase ISEc52 Transposase
E4Z69_RS24290 () 4942883..4943233 - 351 WP_000624722.1 IS66 family transposase ISEc23 Transposase
E4Z69_RS24295 () 4943230..4943655 - 426 WP_000422741.1 IS66 family transposase ISEc23 Transposase
E4Z69_RS24300 () 4943739..4943885 + 147 Protein_4693 Glutathione hydrolase proenzyme VF
E4Z69_RS24305 () 4943925..4944758 - 834 Protein_4694 phosphotriesterase-related protein -
E4Z69_RS24310 () 4945603..4945767 + 165 WP_001128468.1 hypothetical protein -
E4Z69_RS24320 () 4946232..4946777 + 546 WP_000973158.1 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase -
E4Z69_RS24325 () 4946774..4947517 + 744 WP_001297350.1 adenosylcobinamide-GDP ribazoletransferase -
E4Z69_RS24330 () 4947529..4948608 + 1080 WP_001193781.1 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase -
E4Z69_RS24335 () 4948670..4949605 + 936 WP_072972328.1 L,D-transpeptidase -
E4Z69_RS24695 () 4949602..4949796 - 195 WP_058905276.1 hypothetical protein -
E4Z69_RS24345 () 4950139..4950867 + 729 WP_023143484.1 hypothetical protein -
E4Z69_RS24350 () 4950867..4951478 + 612 WP_060617264.1 TIR domain-containing protein -
E4Z69_RS24355 () 4951520..4952032 + 513 WP_002911715.1 TIR domain-containing protein -
E4Z69_RS24360 () 4952034..4953227 + 1194 WP_086415151.1 toll/interleukin-1 receptor domain-containing protein -
E4Z69_RS24365 () 4953224..4954042 + 819 WP_112035140.1 hypothetical protein -
E4Z69_RS24370 () 4954287..4956017 - 1731 WP_071788381.1 ATP-binding protein -
E4Z69_RS24375 () 4956416..4957078 - 663 WP_023143489.1 hypothetical protein -
E4Z69_RS24380 () 4957072..4957563 - 492 WP_002911710.1 TIR domain-containing protein -
E4Z69_RS24385 () 4957585..4958574 - 990 WP_023143490.1 hypothetical protein -
E4Z69_RS24390 () 4958606..4959163 - 558 WP_002911703.1 hypothetical protein -
E4Z69_RS24395 () 4959160..4960245 - 1086 WP_032193687.1 thymidylate synthase -
E4Z69_RS24400 () 4961156..4962103 + 948 WP_002911701.1 DUF1738 domain-containing protein -
E4Z69_RS24405 () 4962298..4963044 - 747 WP_002911700.1 hypothetical protein -
E4Z69_RS24410 () 4963054..4964912 - 1859 Protein_4714 TraM recognition domain-containing protein -
E4Z69_RS24420 () 4965516..4966628 - 1113 WP_001300563.1 IS4 family transposase IS421 Transposase
E4Z69_RS24425 () 4966826..4967851 + 1026 WP_001101446.1 IS110 family transposase ISAve1 Transposase
E4Z69_RS24430 () 4968146..4969114 + 969 WP_000654812.1 IS5 family transposase IS903B Transposase
E4Z69_RS24435 () 4969433..4970458 - 1026 WP_001101446.1 IS110 family transposase ISAve1 Transposase
E4Z69_RS24440 () 4970610..4971467 + 858 WP_001445939.1 RNA polymerase sigma factor RpoH -
E4Z69_RS24445 () 4971725..4971907 - 183 Protein_4720 transposase -
E4Z69_RS24450 () 4971959..4972663 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
E4Z69_RS24455 () 4972727..4973233 - 507 Protein_4722 transcriptional regulator -
E4Z69_RS24460 () 4973561..4974257 + 697 Protein_4723 IS1 family transposase -
E4Z69_RS24465 () 4974410..4975029 - 620 Protein_4724 HlyD family efflux transporter periplasmic adaptor subunit -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance