MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 134924 bp
Accession: NZ_LR216060 Location: 959060..1093983 Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315 Replicon: chromosome
Accession: NZ_LR216060 Location: 959060..1093983 Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0F39_RS05170 () | 954540..955763 | - | 1224 | WP_000222035.1 | peptidase T | - |
| E0F39_RS05175 () | 955918..957012 | + | 1095 | WP_000709247.1 | ferrochelatase | - |
| E0F39_RS05180 () | 957054..957431 | - | 378 | WP_000916795.1 | large conductance mechanosensitive channel protein MscL | - |
| E0F39_RS05185 () | 957513..957944 | - | 432 | WP_000742997.1 | GtrA family protein | - |
| E0F39_RS05190 () | 958067..958576 | + | 510 | WP_000737071.1 | QueT transporter family protein | - |
| E0F39_RS05200 () | 959091..960167 | + | 1077 | WP_000542472.1 | aspartate-semialdehyde dehydrogenase | - |
| E0F39_RS05205 () | 960223..961158 | + | 936 | WP_000121620.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| E0F39_RS05210 () | 961205..962578 | - | 1374 | WP_130886881.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| E0F39_RS05215 () | 962716..962898 | - | 183 | WP_001117397.1 | 4-oxalocrotonate tautomerase | - |
| E0F39_RS05220 () | 963022..963612 | + | 591 | WP_000068143.1 | thymidine kinase | - |
| E0F39_RS05225 () | 963609..964688 | + | 1080 | WP_001028801.1 | peptide chain release factor 1 | - |
| E0F39_RS05230 () | 964688..965527 | + | 840 | WP_000761910.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| E0F39_RS05235 () | 965511..966113 | + | 603 | WP_000567066.1 | threonylcarbamoyl-AMP synthase | - |
| E0F39_RS05240 () | 966115..966546 | + | 432 | WP_000942928.1 | GNAT family N-acetyltransferase | - |
| E0F39_RS05245 () | 966608..967864 | + | 1257 | WP_000575519.1 | serine hydroxymethyltransferase | - |
| E0F39_RS05250 () | 967872..968846 | + | 975 | WP_000356094.1 | nucleoid-associated protein | - |
| E0F39_RS05255 () | 968846..969460 | + | 615 | WP_000476375.1 | cell wall hydrolase Pmp23 | - |
| E0F39_RS05260 () | 969534..970508 | + | 975 | WP_001864712.1 | DUF1002 domain-containing protein | - |
| E0F39_RS05265 () | 970582..972213 | + | 1632 | WP_000914579.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| E0F39_RS05270 () | 972427..972660 | + | 234 | WP_000710799.1 | hypothetical protein | - |
| E0F39_RS05275 () | 972951..973168 | + | 218 | Protein_985 | helix-turn-helix transcriptional regulator | - |
| E0F39_RS05285 () | 973561..974586 | + | 1026 | WP_000790743.1 | iron-siderophore ABC transporter substrate-binding protein | - |
| E0F39_RS05290 () | 974576..975583 | + | 1008 | WP_001244693.1 | Ferric enterobactin transport system permease protein FepD | VF |
| E0F39_RS05295 () | 975583..976590 | + | 1008 | WP_001180357.1 | putative siderophore transport system permease protein YfhA | VF |
| E0F39_RS05300 () | 976590..977384 | + | 795 | WP_000677525.1 | Petrobactin import ATP-binding protein FpuD | VF |
| E0F39_RS05305 () | 977772..978161 | + | 390 | WP_074017679.1 | restriction endonuclease subunit S | - |
| E0F39_RS12215 () | 978133..978441 | + | 309 | WP_162499171.1 | hypothetical protein | - |
| E0F39_RS12315 () | 979125..979286 | + | 162 | WP_000368174.1 | hypothetical protein | - |
| E0F39_RS05320 () | 979378..981061 | + | 1684 | Protein_993 | hypothetical protein ; Integrase | Integrase |
| E0F39_RS05325 () | 981329..981895 | + | 567 | WP_000234983.1 | hypothetical protein | - |
| E0F39_RS05330 () | 982219..982407 | + | 189 | WP_000179769.1 | hypothetical protein | - |
| E0F39_RS05335 () | 982469..983227 | + | 759 | WP_001865182.1 | ATP-grasp domain-containing protein | - |
| E0F39_RS05340 () | 983285..984139 | + | 855 | WP_000900019.1 | ADP-ribosylglycohydrolase family protein | - |
| E0F39_RS05345 () | 984251..985135 | + | 885 | WP_001865183.1 | diacylglycerol kinase family lipid kinase | - |
| E0F39_RS05350 () | 985297..986001 | + | 705 | WP_001865184.1 | alpha amylase N-terminal ig-like domain-containing protein | - |
| E0F39_RS05355 () | 985977..986432 | + | 456 | WP_001865186.1 | hypothetical protein | - |
| E0F39_RS05360 () | 986877..987038 | + | 162 | Protein_1001 | helix-turn-helix transcriptional regulator | - |
| E0F39_RS05365 () | 987041..987709 | + | 669 | Protein_1002 | zeta toxin family protein | - |
| E0F39_RS05370 () | 987737..988513 | + | 777 | Protein_1003 | hypothetical protein | - |
| E0F39_RS05375 () | 988441..988893 | + | 453 | WP_001808559.1 | hypothetical protein | - |
| E0F39_RS05380 () | 989712..990071 | + | 360 | WP_000003750.1 | hypothetical protein | - |
| E0F39_RS05385 () | 990081..990446 | + | 366 | WP_000263054.1 | MobC family plasmid mobilization relaxosome protein | - |
| E0F39_RS05390 () | 990433..992283 | + | 1851 | WP_001865166.1 | relaxase/mobilization nuclease domain-containing protein | - |
| E0F39_RS05395 () | 992539..993971 | + | 1433 | Protein_1008 | IS1182 family transposase | - |
| E0F39_RS05400 () | 994209..994343 | - | 135 | Protein_1009 | transposase family protein | - |
| E0F39_RS05405 () | 994664..995617 | - | 954 | WP_001155321.1 | IS30 family transposase ISSpn8 | Transposase |
| E0F39_RS12460 () | 996001..996404 | + | 404 | Protein_1011 | hypothetical protein | - |
| E0F39_RS05415 () | 996463..997137 | + | 675 | WP_000903082.1 | chloramphenicol acetyltransferase | - |
| E0F39_RS05420 () | 997205..998842 | + | 1638 | WP_000021543.1 | methionine--tRNA ligase | - |
| E0F39_RS05425 () | 998943..999710 | + | 768 | WP_001061789.1 | tyrosine-protein phosphatase | - |
| E0F39_RS05430 () | 1000727..1001719 | + | 993 | WP_024266136.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| E0F39_RS05435 () | 1001721..1002539 | + | 819 | WP_000164265.1 | ABC-2 family transporter protein | - |
| E0F39_RS05440 () | 1002541..1003326 | + | 786 | WP_000760754.1 | ABC transporter permease | - |
| E0F39_RS05445 () | 1003705..1004900 | - | 1196 | Protein_1018 | IS110 family transposase | - |
| E0F39_RS05450 () | 1005402..1005605 | + | 204 | WP_000275922.1 | helix-turn-helix transcriptional regulator | - |
| E0F39_RS12320 () | 1005736..1005888 | + | 153 | WP_001812617.1 | hypothetical protein | - |
| E0F39_RS05455 () | 1006055..1007848 | + | 1794 | WP_001864824.1 | hypothetical protein ; Integrase | Integrase |
| E0F39_RS05460 () | 1007932..1008541 | + | 610 | Protein_1022 | Type 1 glutamine amidotransferase-like domain-containing protein | - |
| E0F39_RS05465 () | 1008823..1009070 | + | 248 | Protein_1023 | aminoglycoside phosphotransferase | - |
| E0F39_RS05470 () | 1009175..1009477 | + | 303 | Protein_1024 | IS5 family transposase IS1381A | Transposase |
| E0F39_RS05475 () | 1009633..1010862 | + | 1230 | WP_050198973.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| E0F39_RS05480 () | 1010882..1013578 | + | 2697 | WP_000058201.1 | phosphoenolpyruvate carboxylase | - |
| E0F39_RS05485 () | 1013991..1014995 | + | 1005 | WP_000792163.1 | hypothetical protein | VF |
| E0F39_RS05490 () | 1015064..1015930 | + | 867 | WP_000637238.1 | ABC transporter permease | - |
| E0F39_RS05495 () | 1015927..1016685 | + | 759 | WP_001864823.1 | ABC transporter ATP-binding protein | - |
| E0F39_RS05500 () | 1016775..1018535 | + | 1761 | WP_000227905.1 | DNA primase | - |
| E0F39_RS05505 () | 1018538..1019647 | + | 1110 | WP_000201898.1 | RNA polymerase sigma factor RpoD | - |
| E0F39_RS05510 () | 1019661..1019990 | + | 330 | WP_000331928.1 | metal-sulfur cluster assembly factor | - |
| E0F39_RS05515 () | 1020105..1021148 | + | 1044 | WP_000412280.1 | alpha-galactosylglucosyldiacylglycerol synthase | - |
| E0F39_RS05520 () | 1021164..1022489 | + | 1326 | WP_001219427.1 | glycosyltransferase family 4 protein | - |
| E0F39_RS05525 () | 1022520..1022696 | + | 177 | WP_001256250.1 | PspC domain-containing protein | - |
| E0F39_RS05530 () | 1022755..1022889 | + | 135 | WP_000863859.1 | DUF4044 domain-containing protein | - |
| E0F39_RS05535 () | 1022953..1024263 | + | 1311 | WP_042756799.1 | GTPase ObgE | - |
| E0F39_RS12325 () | 1024273..1024431 | + | 159 | WP_001808548.1 | hypothetical protein | - |
| E0F39_RS05545 () | 1024558..1025114 | - | 557 | Protein_1039 | ISL3 family transposase IS1167 | Transposase |
| E0F39_RS05550 () | 1026289..1027548 | + | 1260 | WP_001227083.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| E0F39_RS05555 () | 1027564..1028115 | + | 552 | WP_001103684.1 | GNAT family N-acetyltransferase | - |
| E0F39_RS05560 () | 1028108..1029385 | + | 1278 | WP_000033830.1 | CBS-HotDog domain-containing transcription factor SpxR | - |
| E0F39_RS05565 () | 1029401..1030261 | + | 861 | WP_000631543.1 | methionyl aminopeptidase | - |
| E0F39_RS05575 () | 1030640..1031425 | + | 786 | Protein_1044 | IS5 family transposase ISSpn7 | Transposase |
| E0F39_RS05580 () | 1031616..1033907 | + | 2292 | WP_000992853.1 | DNA helicase PcrA | - |
| E0F39_RS05585 () | 1033950..1034630 | + | 681 | WP_000286922.1 | DNA repair protein RadC | - |
| E0F39_RS05590 () | 1034627..1035316 | - | 690 | WP_000743330.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| E0F39_RS05595 () | 1035334..1035975 | - | 642 | WP_000653403.1 | redox-sensing transcriptional repressor Rex | - |
| E0F39_RS05600 () | 1036058..1036273 | - | 216 | WP_000462487.1 | DUF4649 family protein | - |
| E0F39_RS05605 () | 1036281..1036628 | - | 348 | WP_000863509.1 | DUF1831 domain-containing protein | - |
| E0F39_RS05610 () | 1036633..1037748 | - | 1116 | WP_000639664.1 | cysteine desulfurase | - |
| E0F39_RS05615 () | 1037758..1038717 | - | 960 | WP_001283813.1 | ribose-phosphate diphosphokinase | - |
| E0F39_RS05620 () | 1038830..1039399 | - | 570 | WP_000681293.1 | CYTH domain-containing protein | - |
| E0F39_RS05625 () | 1039527..1040198 | + | 672 | WP_000171686.1 | GTP pyrophosphokinase family protein | - |
| E0F39_RS05630 () | 1040182..1041000 | + | 819 | WP_000799053.1 | NAD kinase | - |
| E0F39_RS05635 () | 1040997..1041893 | + | 897 | WP_001210010.1 | RluA family pseudouridine synthase | - |
| E0F39_RS05640 () | 1041937..1042911 | + | 975 | WP_000451584.1 | phosphate acetyltransferase | - |
| E0F39_RS05645 () | 1043253..1043552 | - | 300 | WP_000981526.1 | YbaB/EbfC family nucleoid-associated protein | - |
| E0F39_RS05650 () | 1043954..1044652 | + | 699 | WP_000509041.1 | DUF1275 domain-containing protein | - |
| E0F39_RS05655 () | 1044840..1045154 | + | 315 | WP_000109141.1 | 50S ribosomal protein L21 | - |
| E0F39_RS05660 () | 1045170..1045514 | + | 345 | WP_000613699.1 | ribosomal-processing cysteine protease Prp | - |
| E0F39_RS05665 () | 1045531..1045824 | + | 294 | WP_000916509.1 | 50S ribosomal protein L27 | - |
| E0F39_RS05675 () | 1046135..1046340 | - | 206 | Protein_1063 | ABC transporter substrate-binding protein | - |
| E0F39_RS05680 () | 1046778..1047695 | + | 918 | WP_000587444.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| E0F39_RS05685 () | 1047788..1048636 | - | 849 | WP_000592059.1 | YitT family protein | - |
| E0F39_RS05690 () | 1048778..1049617 | + | 840 | WP_000161387.1 | DegV family protein | - |
| E0F39_RS05695 () | 1049724..1049999 | + | 276 | WP_001284639.1 | HU family DNA-binding protein | - |
| E0F39_RS05700 () | 1050425..1052326 | + | 1902 | WP_000584880.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| E0F39_RS05705 () | 1052329..1053192 | + | 864 | WP_000400550.1 | XRE/MutR family transcriptional regulator | - |
| E0F39_RS05710 () | 1053272..1054450 | + | 1179 | WP_001083024.1 | MFS transporter | - |
| E0F39_RS05715 () | 1054543..1056501 | + | 1959 | WP_001042599.1 | NAD-dependent DNA ligase LigA | - |
| E0F39_RS05720 () | 1056613..1058892 | + | 2280 | WP_000283084.1 | type I pullulanase | - |
| E0F39_RS05725 () | 1059450..1060874 | + | 1425 | WP_001865072.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| E0F39_RS05735 () | 1061357..1063285 | + | 1929 | WP_050199095.1 | 1,4-alpha-glucan branching protein GlgB | - |
| E0F39_RS05740 () | 1063275..1064417 | + | 1143 | WP_050199094.1 | glucose-1-phosphate adenylyltransferase | - |
| E0F39_RS05745 () | 1064407..1065546 | + | 1140 | WP_001865102.1 | glucose-1-phosphate adenylyltransferase subunit GlgD | - |
| E0F39_RS05750 () | 1065543..1066976 | + | 1434 | WP_000697295.1 | glycogen synthase GlgA | - |
| E0F39_RS05755 () | 1067035..1067679 | + | 645 | WP_001865103.1 | phosphoserine phosphatase SerB | - |
| E0F39_RS05760 () | 1067688..1068803 | + | 1116 | WP_001865104.1 | glycerate kinase | - |
| E0F39_RS05765 () | 1068800..1069246 | - | 447 | WP_054385037.1 | YueI family protein | - |
| E0F39_RS05770 () | 1069410..1070714 | + | 1305 | WP_000022813.1 | phosphopyruvate hydratase | - |
| E0F39_RS12330 () | 1070868..1071000 | - | 133 | Protein_1082 | ISL3 family transposase | - |
| E0F39_RS05780 () | 1071097..1071495 | + | 399 | WP_050199111.1 | hypothetical protein | - |
| E0F39_RS05785 () | 1071967..1072197 | + | 231 | WP_001865346.1 | hypothetical protein | - |
| E0F39_RS05790 () | 1072190..1072465 | + | 276 | WP_001865345.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| E0F39_RS05795 () | 1072539..1073117 | + | 579 | WP_001865343.1 | replication protein | - |
| E0F39_RS12070 () | 1073129..1073284 | + | 156 | WP_153297226.1 | hypothetical protein | - |
| E0F39_RS05800 () | 1073392..1073688 | + | 297 | WP_001865342.1 | hypothetical protein | - |
| E0F39_RS05805 () | 1073669..1073965 | + | 297 | WP_130886882.1 | hypothetical protein | - |
| E0F39_RS05810 () | 1073930..1074744 | - | 815 | Protein_1090 | IS5 family transposase IS1515 | Transposase |
| E0F39_RS05820 () | 1074801..1075208 | + | 408 | WP_078133849.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| E0F39_RS05825 () | 1075208..1075978 | + | 771 | WP_050202097.1 | zeta toxin family protein | Toxin Detail |
| E0F39_RS05830 () | 1076332..1077228 | - | 897 | WP_000384882.1 | Tyrosine recombinase XerD | VF |
| E0F39_RS05835 () | 1077320..1079599 | + | 2280 | WP_050198960.1 | ATP-binding protein | - |
| E0F39_RS05840 () | 1079583..1080824 | - | 1242 | WP_001865081.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| E0F39_RS05845 () | 1081470..1083569 | + | 2100 | WP_001865078.1 | AAA family ATPase | - |
| E0F39_RS05850 () | 1083556..1085373 | + | 1818 | WP_001865077.1 | ATP-dependent helicase | - |
| E0F39_RS05855 () | 1085459..1086634 | - | 1176 | WP_050198961.1 | ATP-binding protein | - |
| E0F39_RS05865 () | 1086996..1087352 | + | 357 | WP_000817623.1 | hypothetical protein | - |
| E0F39_RS05870 () | 1087357..1087722 | + | 366 | WP_000401239.1 | MobC family plasmid mobilization relaxosome protein | - |
| E0F39_RS05875 () | 1087709..1089532 | + | 1824 | WP_000237144.1 | relaxase/mobilization nuclease domain-containing protein | - |
| E0F39_RS05880 () | 1089646..1090512 | + | 867 | WP_000537005.1 | helix-turn-helix domain-containing protein | - |
| E0F39_RS05885 () | 1091103..1091354 | + | 252 | WP_000098314.1 | hypothetical protein | - |
| E0F39_RS05890 () | 1091583..1091885 | + | 303 | WP_000792536.1 | hypothetical protein | - |
| E0F39_RS05895 () | 1091882..1093228 | + | 1347 | WP_001105427.1 | protein kinase | - |
| E0F39_RS05900 () | 1093242..1094159 | + | 918 | WP_000995575.1 | ABC transporter ATP-binding protein | - |
| E0F39_RS05905 () | 1094156..1094956 | + | 801 | WP_000642567.1 | ABC transporter permease | - |
| E0F39_RS05910 () | 1095114..1095587 | + | 474 | WP_001206385.1 | IS200/IS605-like element ISSpn6 family transposase | - |
| E0F39_RS05915 () | 1095844..1096065 | + | 222 | WP_001864746.1 | helix-turn-helix domain-containing protein | - |
| E0F39_RS05920 () | 1096367..1096600 | + | 234 | WP_000404196.1 | hypothetical protein | - |
| E0F39_RS05925 () | 1096676..1098184 | + | 1509 | WP_050198962.1 | site-specific integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|