MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 151241 bp
Accession: NZ_LR135357 Location: 2198658..2349898 Organism: Enterococcus faecium isolate E7948 Replicon: chromosome
Accession: NZ_LR135357 Location: 2198658..2349898 Organism: Enterococcus faecium isolate E7948 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQB40_RS11160 () | 2195634..2195945 | - | 312 | WP_002296825.1 | hypothetical protein | - |
| EQB40_RS11165 () | 2196126..2197601 | + | 1476 | WP_002286329.1 | UbiD family decarboxylase | - |
| EQB40_RS11170 () | 2197648..2198232 | + | 585 | WP_002286331.1 | UbiX family flavin prenyltransferase | - |
| EQB40_RS11175 () | 2198234..2198653 | + | 420 | WP_002286333.1 | hypothetical protein | - |
| EQB40_RS11185 () | 2198934..2199218 | - | 285 | WP_002286335.1 | DUF1905 domain-containing protein | - |
| EQB40_RS11195 () | 2199570..2200280 | - | 711 | WP_002286342.1 | DUF4811 domain-containing protein | - |
| EQB40_RS11200 () | 2200277..2201749 | - | 1473 | WP_002286343.1 | multidrug efflux MFS transporter | - |
| EQB40_RS11205 () | 2201887..2202360 | + | 474 | WP_002286344.1 | MerR family transcriptional regulator | - |
| EQB40_RS11210 () | 2202513..2203064 | - | 552 | WP_002286354.1 | PadR family transcriptional regulator | - |
| EQB40_RS11215 () | 2203169..2203699 | + | 531 | WP_002286355.1 | phenolic acid decarboxylase | - |
| EQB40_RS11220 () | 2204182..2204625 | - | 444 | WP_002286361.1 | GNAT family N-acetyltransferase | - |
| EQB40_RS11225 () | 2204641..2205801 | - | 1161 | WP_002286364.1 | hypothetical protein | VF |
| EQB40_RS11235 () | 2206308..2208008 | + | 1701 | WP_080440836.1 | hypothetical protein | - |
| EQB40_RS11240 () | 2208110..2208943 | - | 834 | WP_002286367.1 | endonuclease/exonuclease/phosphatase family protein | - |
| EQB40_RS11245 () | 2209247..2211412 | - | 2166 | WP_002286368.1 | PTS transporter subunit IIBC | - |
| EQB40_RS11250 () | 2211672..2213966 | + | 2295 | WP_002286373.1 | glycoside hydrolase family 65 protein | - |
| EQB40_RS11255 () | 2213959..2214624 | + | 666 | WP_002286375.1 | beta-phosphoglucomutase | - |
| EQB40_RS11260 () | 2214617..2215624 | + | 1008 | WP_002294627.1 | galactose mutarotase | - |
| EQB40_RS11265 () | 2215646..2216665 | + | 1020 | WP_002286379.1 | Catabolite control protein A | VF |
| EQB40_RS11270 () | 2216946..2218313 | - | 1368 | WP_002286385.1 | Na+/H+ antiporter NhaC | - |
| EQB40_RS11275 () | 2218422..2219843 | - | 1422 | WP_002286392.1 | APC family permease | - |
| EQB40_RS11280 () | 2220086..2221963 | - | 1878 | WP_002286400.1 | tyrosine decarboxylase | - |
| EQB40_RS11285 () | 2222254..2223510 | - | 1257 | WP_002286405.1 | tyrosine--tRNA ligase | - |
| EQB40_RS11290 () | 2224090..2225391 | + | 1302 | WP_002296829.1 | polysaccharide deacetylase family protein | - |
| EQB40_RS11295 () | 2225460..2226059 | - | 600 | WP_002294634.1 | TetR/AcrR family transcriptional regulator | - |
| EQB40_RS11300 () | 2226314..2227195 | + | 882 | WP_002289288.1 | Multidrug efflux system ATP-binding protein | VF |
| EQB40_RS11305 () | 2227208..2228818 | + | 1611 | WP_060806686.1 | hypothetical protein | - |
| EQB40_RS11310 () | 2228895..2229554 | - | 660 | WP_002289290.1 | Crp/Fnr family transcriptional regulator | - |
| EQB40_RS11315 () | 2229837..2230502 | - | 666 | WP_002289292.1 | glucose-6-phosphate 1-dehydrogenase family protein | - |
| EQB40_RS11325 () | 2230649..2231254 | - | 606 | WP_002289293.1 | dihydroxyacetone kinase subunit L | - |
| EQB40_RS11330 () | 2231282..2232292 | - | 1011 | WP_002289294.1 | dihydroxyacetone kinase subunit DhaK | - |
| EQB40_RS11335 () | 2232267..2232713 | - | 447 | WP_002289295.1 | PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM | - |
| EQB40_RS11340 () | 2232816..2233136 | + | 321 | WP_002289297.1 | heavy metal-binding domain-containing protein | - |
| EQB40_RS11345 () | 2233248..2234117 | - | 870 | WP_002294641.1 | LPXTG cell wall anchor domain-containing protein | - |
| EQB40_RS11350 () | 2234213..2235517 | - | 1305 | WP_002289301.1 | Poly-beta-1,6-N-acetyl-D-glucosamine synthase | VF |
| EQB40_RS11355 () | 2235514..2236023 | - | 510 | WP_002294644.1 | hypothetical protein | - |
| EQB40_RS11360 () | 2236198..2238333 | - | 2136 | WP_002296832.1 | AAA family ATPase | - |
| EQB40_RS11365 () | 2238416..2239639 | - | 1224 | Protein_2107 | FAD-dependent oxidoreductase | - |
| EQB40_RS11370 () | 2239715..2240395 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB40_RS11375 () | 2240497..2240556 | + | 60 | WP_002503927.1 | 23S rRNA methylase leader peptide ErmCL | - |
| EQB40_RS11380 () | 2240616..2241350 | + | 735 | WP_002345002.1 | rRNA adenine N-6-methyltransferase | ARG |
| EQB40_RS11385 () | 2241917..2242996 | + | 1080 | WP_002326691.1 | IS30 family transposase ISCth3 | Transposase |
| EQB40_RS11390 () | 2243491..2244171 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB40_RS11395 () | 2244194..2245081 | - | 888 | WP_025479406.1 | protein rep | - |
| EQB40_RS11400 () | 2245326..2246588 | - | 1263 | WP_000119405.1 | plasmid recombination protein | - |
| EQB40_RS11410 () | 2247152..2248525 | - | 1374 | WP_060806738.1 | tetracycline efflux MFS transporter Tet(L) | ARG |
| EQB40_RS11415 () | 2248623..2250542 | - | 1920 | WP_002345005.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| EQB40_RS11420 () | 2250558..2250674 | - | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| EQB40_RS11425 () | 2250919..2251833 | - | 915 | WP_002345006.1 | conjugal transfer protein | - |
| EQB40_RS11430 () | 2251848..2252849 | - | 1002 | WP_002345007.1 | hypothetical protein | VF |
| EQB40_RS11435 () | 2252846..2255029 | - | 2184 | WP_002345008.1 | membrane protein | - |
| EQB40_RS11440 () | 2255032..2257479 | - | 2448 | WP_000331148.1 | ATP-binding protein | - |
| EQB40_RS11445 () | 2257463..2257855 | - | 393 | WP_002345009.1 | conjugal transfer protein | - |
| EQB40_RS11450 () | 2257942..2258439 | - | 498 | WP_002345010.1 | antirestriction protein ArdA | - |
| EQB40_RS11455 () | 2258556..2258780 | - | 225 | WP_032509114.1 | hypothetical protein | - |
| EQB40_RS11460 () | 2258884..2260794 | - | 1911 | WP_002286940.1 | group II intron reverse transcriptase/maturase | - |
| EQB40_RS11465 () | 2261578..2262783 | - | 1206 | WP_000398284.1 | replication initiation factor domain-containing protein | - |
| EQB40_RS11470 () | 2262806..2262959 | - | 154 | Protein_2127 | conjugal transfer protein | - |
| EQB40_RS11475 () | 2262962..2264347 | - | 1386 | WP_000813488.1 | DNA translocase FtsK | - |
| EQB40_RS11480 () | 2264376..2264762 | - | 387 | WP_000985015.1 | YdcP family protein | - |
| EQB40_RS11485 () | 2264778..2265092 | - | 315 | WP_000420682.1 | YdcP family protein | - |
| EQB40_RS11495 () | 2265445..2265924 | - | 480 | WP_002345011.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| EQB40_RS11500 () | 2266352..2267641 | + | 1290 | WP_002290101.1 | Serine protease Do-like HtrA | VF |
| EQB40_RS11505 () | 2267680..2268285 | - | 606 | WP_002313997.1 | DUF4479 domain-containing tRNA-binding protein | - |
| EQB40_RS11515 () | 2268481..2268945 | - | 465 | WP_002345012.1 | universal stress protein | - |
| EQB40_RS11520 () | 2268967..2269287 | - | 321 | WP_002292632.1 | thioredoxin family protein | - |
| EQB40_RS11525 () | 2269430..2270509 | - | 1080 | WP_002294156.1 | glutamyl aminopeptidase | - |
| EQB40_RS11530 () | 2270709..2271059 | + | 351 | WP_002309710.1 | PepSY domain-containing protein | - |
| EQB40_RS11535 () | 2271244..2272197 | + | 954 | WP_002299300.1 | glycosyltransferase family 2 protein | - |
| EQB40_RS11540 () | 2272210..2273997 | + | 1788 | WP_002299301.1 | hypothetical protein | - |
| EQB40_RS11545 () | 2273984..2275186 | + | 1203 | WP_002299302.1 | hypothetical protein | - |
| EQB40_RS11555 () | 2275391..2276686 | + | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| EQB40_RS11560 () | 2276784..2278202 | - | 1419 | WP_002294157.1 | dipeptidase PepV | - |
| EQB40_RS11565 () | 2278351..2279196 | + | 846 | WP_002299303.1 | NAD(P)H-hydrate dehydratase | - |
| EQB40_RS11570 () | 2279200..2279640 | + | 441 | WP_002301667.1 | acyl-CoA thioesterase | - |
| EQB40_RS11575 () | 2279690..2279884 | + | 195 | WP_002315615.1 | hypothetical protein | - |
| EQB40_RS11580 () | 2280020..2280705 | + | 686 | Protein_2146 | GntR family transcriptional regulator | - |
| EQB40_RS11590 () | 2281113..2281802 | - | 690 | WP_002302159.1 | hypothetical protein | - |
| EQB40_RS11595 () | 2281777..2283906 | - | 2130 | WP_002341584.1 | hydantoinase/oxoprolinase | - |
| EQB40_RS11600 () | 2283954..2284850 | - | 897 | WP_080388548.1 | citrate transporter | - |
| EQB40_RS11605 () | 2284947..2286134 | + | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| EQB40_RS11610 () | 2286241..2286582 | - | 342 | WP_002341586.1 | hypothetical protein | - |
| EQB40_RS11615 () | 2287018..2287377 | - | 360 | WP_002289310.1 | 50S ribosomal protein L20 | - |
| EQB40_RS11620 () | 2287430..2287630 | - | 201 | WP_002289309.1 | 50S ribosomal protein L35 | - |
| EQB40_RS11625 () | 2287702..2288226 | - | 525 | WP_002293357.1 | translation initiation factor IF-3 | - |
| EQB40_RS11630 () | 2288546..2289178 | + | 633 | WP_002300053.1 | pentapeptide repeat-containing protein | - |
| EQB40_RS11635 () | 2289180..2290085 | - | 906 | WP_002300052.1 | magnesium transporter CorA family protein | - |
| EQB40_RS11640 () | 2290170..2290829 | - | 660 | WP_002352356.1 | deoxynucleoside kinase | - |
| EQB40_RS11645 () | 2291145..2292089 | + | 945 | WP_002288231.1 | mevalonate kinase | - |
| EQB40_RS11650 () | 2292082..2293059 | + | 978 | WP_002300050.1 | diphosphomevalonate decarboxylase | - |
| EQB40_RS11655 () | 2293072..2294157 | + | 1086 | WP_002288233.1 | phosphomevalonate kinase | - |
| EQB40_RS11660 () | 2294154..2295218 | + | 1065 | WP_002300048.1 | type 2 isopentenyl-diphosphate Delta-isomerase | - |
| EQB40_RS11665 () | 2295467..2296270 | - | 804 | WP_033582433.1 | 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase | VF |
| EQB40_RS11670 () | 2296290..2296595 | - | 306 | WP_002300046.1 | 5-dehydro-4-deoxy-D-glucuronate isomerase | - |
| EQB40_RS11675 () | 2296577..2296783 | - | 207 | WP_126145175.1 | TRAP transporter large permease subunit | - |
| EQB40_RS11685 () | 2298198..2298776 | - | 579 | WP_002300787.1 | TRAP transporter large permease subunit | - |
| EQB40_RS11690 () | 2298792..2299271 | - | 480 | WP_002300788.1 | TRAP transporter small permease | - |
| EQB40_RS11695 () | 2299277..2300301 | - | 1025 | Protein_2168 | TRAP transporter substrate-binding protein | - |
| EQB40_RS11700 () | 2300318..2301424 | - | 1107 | WP_002288261.1 | glycosyl hydrolase | - |
| EQB40_RS11705 () | 2301653..2304250 | - | 2598 | WP_002296567.1 | Aldehyde-alcohol dehydrogenase | VF |
| EQB40_RS11710 () | 2304556..2304936 | - | 381 | WP_002294182.1 | preprotein translocase subunit YajC | - |
| EQB40_RS11715 () | 2305033..2306178 | - | 1146 | WP_002294183.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| EQB40_RS11720 () | 2306396..2307094 | + | 699 | WP_002296566.1 | DUF975 family protein | - |
| EQB40_RS11725 () | 2307262..2309901 | - | 2640 | WP_002289743.1 | cation-translocating P-type ATPase | - |
| EQB40_RS11730 () | 2310520..2311551 | - | 1032 | WP_002296565.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| EQB40_RS11735 () | 2311744..2312349 | + | 606 | Protein_2176 | Carnitine transport ATP-binding protein OpuCA | VF |
| EQB40_RS11740 () | 2312502..2313650 | - | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB40_RS11745 () | 2313667..2314071 | - | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB40_RS11750 () | 2314229..2314810 | + | 582 | Protein_2179 | CBS domain-containing protein | - |
| EQB40_RS11755 () | 2314814..2315455 | + | 642 | WP_002293405.1 | ABC transporter permease | - |
| EQB40_RS11760 () | 2315452..2316369 | + | 918 | WP_002296564.1 | osmoprotectant ABC transporter substrate-binding protein | - |
| EQB40_RS11765 () | 2316366..2317037 | + | 672 | WP_002302663.1 | ABC transporter permease | - |
| EQB40_RS11770 () | 2317578..2318066 | - | 489 | WP_002296561.1 | mannosyl-glycoprotein endo-beta-N-acetylglucosamidase | - |
| EQB40_RS11775 () | 2318267..2318533 | - | 267 | WP_002296560.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EQB40_RS11780 () | 2318533..2318796 | - | 264 | WP_002296559.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EQB40_RS11790 () | 2319272..2319457 | + | 186 | WP_002296558.1 | transcriptional regulator | - |
| EQB40_RS11795 () | 2319599..2321422 | - | 1824 | WP_002294202.1 | APC family permease | - |
| EQB40_RS11805 () | 2322020..2324725 | - | 2706 | WP_002296556.1 | YhgE/Pip domain-containing protein | - |
| EQB40_RS11810 () | 2325031..2325978 | - | 948 | WP_002294206.1 | NADP-dependent oxidoreductase | - |
| EQB40_RS11815 () | 2326168..2326437 | + | 270 | WP_060806742.1 | 30S ribosomal protein S14 | - |
| EQB40_RS11825 () | 2326613..2326975 | - | 363 | WP_002289874.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| EQB40_RS11830 () | 2326986..2328107 | - | 1122 | WP_002296555.1 | alanine racemase | - |
| EQB40_RS11835 () | 2328123..2328473 | - | 351 | WP_002296554.1 | holo-ACP synthase | - |
| EQB40_RS11840 () | 2328603..2330114 | - | 1512 | WP_002296553.1 | DEAD/DEAH box helicase | - |
| EQB40_RS11845 () | 2330436..2331788 | - | 1353 | WP_002304063.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| EQB40_RS11850 () | 2331941..2333017 | - | 1077 | WP_002293424.1 | D-alanine--D-alanine ligase | - |
| EQB40_RS11855 () | 2333213..2334958 | + | 1746 | WP_002296551.1 | AarF/ABC1/UbiB kinase family protein | - |
| EQB40_RS11860 () | 2335238..2335675 | - | 438 | WP_002296550.1 | YaiI/YqxD family protein | - |
| EQB40_RS11865 () | 2335659..2337032 | - | 1374 | WP_002296549.1 | hypothetical protein | - |
| EQB40_RS11870 () | 2337354..2337842 | - | 489 | WP_002296548.1 | GNAT family N-acetyltransferase | - |
| EQB40_RS11875 () | 2337864..2338466 | - | 603 | WP_002294220.1 | TVP38/TMEM64 family protein | - |
| EQB40_RS11880 () | 2338565..2339904 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| EQB40_RS11890 () | 2340389..2341018 | - | 630 | WP_002289751.1 | uridine kinase | - |
| EQB40_RS11895 () | 2341102..2341797 | - | 696 | WP_002289749.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| EQB40_RS11900 () | 2341810..2342526 | - | 717 | WP_002289747.1 | pseudouridine synthase | - |
| EQB40_RS11905 () | 2342856..2343461 | + | 606 | WP_002289745.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| EQB40_RS11910 () | 2343786..2344109 | + | 324 | WP_002289744.1 | DUF960 domain-containing protein | - |
| EQB40_RS11915 () | 2344291..2345661 | + | 1371 | WP_002289277.1 | MATE family efflux transporter | - |
| EQB40_RS11920 () | 2345791..2347092 | - | 1302 | WP_002289278.1 | hemolysin family protein | - |
| EQB40_RS11925 () | 2347322..2349280 | - | 1959 | WP_002321207.1 | KUP/HAK/KT family potassium transporter | - |
| EQB40_RS11930 () | 2349457..2349723 | - | 267 | WP_002289280.1 | GlsB/YeaQ/YmgE family stress response membrane protein | - |
| EQB40_RS11940 () | 2350233..2352359 | - | 2127 | WP_002297086.1 | polyribonucleotide nucleotidyltransferase | - |
| EQB40_RS11945 () | 2352547..2352816 | - | 270 | WP_002289282.1 | 30S ribosomal protein S15 | - |
| EQB40_RS11950 () | 2353067..2353630 | + | 564 | WP_002289284.1 | peptide deformylase | - |
| EQB40_RS11960 () | 2353883..2354404 | - | 522 | WP_002294232.1 | transcription repressor NadR | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|