MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 162848 bp
Accession: NZ_LR135325 Location: 1..162848 Organism: Enterococcus faecium isolate E7654 Replicon: plasmid 2
Accession: NZ_LR135325 Location: 1..162848 Organism: Enterococcus faecium isolate E7654 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQB39_RS14440 () | 1..1041 | + | 1041 | WP_002326172.1 | replication initiator protein A | - |
| EQB39_RS14445 () | 1865..2197 | + | 333 | WP_002323647.1 | hypothetical protein | - |
| EQB39_RS14450 () | 2816..3157 | + | 342 | WP_002295674.1 | DUF5406 domain-containing protein | - |
| EQB39_RS14455 () | 3394..4644 | - | 1251 | WP_002297404.1 | IS110 family transposase ISSpn10 | Transposase |
| EQB39_RS14460 () | 5054..7426 | + | 2373 | WP_002305801.1 | hypothetical protein | - |
| EQB39_RS14465 () | 7487..8947 | + | 1461 | WP_002347152.1 | toprim domain-containing protein | - |
| EQB39_RS14470 () | 8958..10967 | + | 2010 | WP_127817642.1 | DNA topoisomerase 3 | - |
| EQB39_RS16220 () | 11083..11232 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| EQB39_RS14480 () | 11313..11909 | + | 597 | WP_002299811.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EQB39_RS14485 () | 11922..12821 | + | 900 | WP_002301800.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EQB39_RS14490 () | 12824..12955 | + | 132 | WP_002301801.1 | single-stranded DNA-binding protein | - |
| EQB39_RS14495 () | 12977..13309 | + | 333 | WP_002305808.1 | single-stranded DNA-binding protein | - |
| EQB39_RS14500 () | 13331..13588 | + | 258 | WP_002295625.1 | hypothetical protein | - |
| EQB39_RS14505 () | 13747..13869 | - | 123 | WP_002295624.1 | putative holin-like toxin | - |
| EQB39_RS14510 () | 14059..14283 | + | 225 | WP_002305809.1 | hypothetical protein | - |
| EQB39_RS14520 () | 14726..14932 | + | 207 | WP_002305810.1 | hypothetical protein | - |
| EQB39_RS14525 () | 14932..15183 | + | 252 | WP_002300797.1 | hypothetical protein | - |
| EQB39_RS16225 () | 15199..15354 | + | 156 | WP_002300799.1 | hypothetical protein | - |
| EQB39_RS14530 () | 15364..15636 | + | 273 | WP_002300801.1 | hypothetical protein | - |
| EQB39_RS14540 () | 16081..16260 | + | 180 | WP_002300804.1 | hypothetical protein | - |
| EQB39_RS14545 () | 16319..16675 | + | 357 | WP_002311569.1 | hypothetical protein | - |
| EQB39_RS14555 () | 17644..18597 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
| EQB39_RS14560 () | 18718..18981 | + | 264 | WP_002300807.1 | uberolysin/carnocyclin family circular bacteriocin | - |
| EQB39_RS14570 () | 19353..20531 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EQB39_RS14575 () | 20920..22866 | + | 1947 | WP_002300833.1 | PTS sugar transporter subunit IIA | - |
| EQB39_RS14580 () | 22869..23324 | + | 456 | WP_002300835.1 | PTS sugar transporter subunit IIA | - |
| EQB39_RS14585 () | 23338..24666 | + | 1329 | WP_002300836.1 | PTS galactitol transporter subunit IIC | - |
| EQB39_RS14590 () | 24700..24984 | + | 285 | WP_002300838.1 | PTS sugar transporter subunit IIB | - |
| EQB39_RS14595 () | 24986..25501 | + | 516 | WP_002300840.1 | YjbQ family protein | - |
| EQB39_RS14600 () | 25517..26179 | + | 663 | WP_002300841.1 | Ribulose-phosphate 3-epimerase | VF |
| EQB39_RS14605 () | 26186..26758 | + | 573 | WP_002300842.1 | 3-hexulose-6-phosphate isomerase | VF |
| EQB39_RS14610 () | 26945..28465 | - | 1521 | WP_002300843.1 | IS66 family transposase ISDeal1 | Transposase |
| EQB39_RS14615 () | 28708..28893 | - | 186 | WP_002305884.1 | IS66 family transposase ISEbi1 | Transposase |
| EQB39_RS14620 () | 28877..29059 | - | 183 | WP_002300846.1 | hypothetical protein | - |
| EQB39_RS14625 () | 29300..29518 | + | 219 | Protein_34 | IS256 family transposase ISLgar5 | Transposase |
| EQB39_RS14630 () | 30013..30612 | + | 600 | WP_002301839.1 | Tyrosine recombinase XerC | VF |
| EQB39_RS14635 () | 30676..31275 | + | 600 | WP_002322465.1 | bacteriophage abortive infection AbiH family protein | - |
| EQB39_RS14640 () | 31305..31985 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB39_RS14645 () | 32320..33192 | - | 873 | WP_002292418.1 | ROK family protein | - |
| EQB39_RS14650 () | 33456..35402 | - | 1947 | WP_002293868.1 | sucrose-specific PTS transporter subunit IIBC | - |
| EQB39_RS14655 () | 35587..37026 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
| EQB39_RS14660 () | 37028..37990 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| EQB39_RS14670 () | 39829..40284 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
| EQB39_RS14680 () | 40549..40647 | + | 99 | Protein_44 | IS30 family transposase | - |
| EQB39_RS14690 () | 41330..42148 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EQB39_RS14695 () | 42309..42998 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EQB39_RS14700 () | 43012..44514 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EQB39_RS14705 () | 44527..45003 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| EQB39_RS14710 () | 45100..45210 | - | 111 | Protein_49 | transposase | - |
| EQB39_RS14730 () | 47781..48299 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EQB39_RS14740 () | 49030..50304 | - | 1275 | WP_002398627.1 | ISL3 family transposase IS1476 | Transposase |
| EQB39_RS14750 () | 51884..52969 | + | 1086 | WP_002301591.1 | tyrosine recombinase XerS | - |
| EQB39_RS14755 () | 53077..54030 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
| EQB39_RS14760 () | 54161..55411 | - | 1251 | WP_002301126.1 | PTS sugar transporter subunit IIC | - |
| EQB39_RS14765 () | 55430..56356 | - | 927 | WP_002298736.1 | PEP phosphonomutase | - |
| EQB39_RS14770 () | 56435..57430 | - | 996 | WP_002301128.1 | tagatose-bisphosphate aldolase | - |
| EQB39_RS14775 () | 57446..58615 | - | 1170 | WP_002301130.1 | SIS domain-containing protein | - |
| EQB39_RS14780 () | 58631..59365 | - | 735 | WP_002301131.1 | GntR family transcriptional regulator | - |
| EQB39_RS14790 () | 61867..63159 | - | 1293 | WP_002301811.1 | IS256 family transposase ISBsu2 | Transposase |
| EQB39_RS14795 () | 63433..63693 | - | 261 | WP_002313174.1 | hypothetical protein | - |
| EQB39_RS14800 () | 63944..65122 | + | 1179 | WP_002346943.1 | IS256 family transposase ISEf1 | Transposase |
| EQB39_RS14805 () | 65474..65683 | + | 210 | WP_065305666.1 | IS3 family transposase ISEfa8 | Transposase |
| EQB39_RS14810 () | 65655..66440 | - | 786 | Protein_65 | IS3 family transposase | - |
| EQB39_RS14815 () | 66642..67037 | - | 396 | WP_002287876.1 | aspartate 1-decarboxylase | - |
| EQB39_RS14820 () | 67047..67895 | - | 849 | WP_002287875.1 | pantoate--beta-alanine ligase | - |
| EQB39_RS14825 () | 67910..68737 | - | 828 | WP_002287874.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| EQB39_RS14830 () | 68749..69609 | - | 861 | WP_002349114.1 | Rossmann-like and DUF2520 domain-containing protein | - |
| EQB39_RS14835 () | 69847..70332 | + | 486 | Protein_70 | IS256 family transposase ISEfa13 | Transposase |
| EQB39_RS14840 () | 70415..70609 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| EQB39_RS14845 () | 70599..70952 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| EQB39_RS14850 () | 71054..72601 | + | 1548 | WP_002299190.1 | IS66 family transposase ISRob1 | Transposase |
| EQB39_RS14855 () | 72674..73369 | + | 696 | Protein_74 | IS256 family transposase ISEfa13 | Transposase |
| EQB39_RS14860 () | 73652..74332 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB39_RS14865 () | 74876..76048 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EQB39_RS14870 () | 76178..76939 | - | 762 | Protein_77 | APH(2'')-Ia/If/Ih family aminoglycoside O-phosphotransferase | - |
| EQB39_RS14875 () | 77110..78297 | - | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| EQB39_RS14880 () | 78408..78962 | - | 555 | Protein_79 | GNAT family N-acetyltransferase | - |
| EQB39_RS14885 () | 79017..79193 | - | 177 | Protein_80 | IS6 family transposase | - |
| EQB39_RS14890 () | 79353..80390 | - | 1038 | WP_002303110.1 | IS3 family transposase ISSde10 | Transposase |
| EQB39_RS14895 () | 80387..80899 | - | 513 | WP_002387940.1 | IS3 family transposase ISPa31 | Transposase |
| EQB39_RS14900 () | 80969..81223 | - | 255 | Protein_83 | replication initiation protein | - |
| EQB39_RS14905 () | 81567..82247 | - | 681 | WP_002319817.1 | IS6 family transposase IS1297 | Transposase |
| EQB39_RS14915 () | 82317..82697 | + | 381 | Protein_85 | IS6 family transposase IS1216V | Transposase |
| EQB39_RS14920 () | 82792..83034 | + | 243 | Protein_86 | mobilization protein | - |
| EQB39_RS14930 () | 83108..83788 | + | 681 | WP_002319817.1 | IS6 family transposase IS1297 | Transposase |
| EQB39_RS14935 () | 84048..84653 | + | 606 | WP_002321606.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| EQB39_RS14940 () | 84698..84865 | - | 168 | WP_000824191.1 | hypothetical protein | - |
| EQB39_RS14945 () | 84899..85198 | - | 300 | WP_000366408.1 | BRCT domain-containing protein | - |
| EQB39_RS14950 () | 85239..85856 | - | 618 | WP_001224538.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EQB39_RS14955 () | 86181..86576 | - | 396 | WP_002304891.1 | hypothetical protein | - |
| EQB39_RS14960 () | 86656..89007 | - | 2352 | WP_000344083.1 | DUF1906 domain-containing protein | - |
| EQB39_RS14965 () | 89132..89821 | - | 690 | WP_000718009.1 | hypothetical protein | - |
| EQB39_RS14970 () | 89835..90287 | - | 453 | WP_000751236.1 | hypothetical protein | - |
| EQB39_RS14975 () | 90418..91098 | + | 681 | WP_002325565.1 | IS6 family transposase IS1216E | Transposase |
| EQB39_RS14980 () | 91200..92519 | - | 1320 | WP_002300494.1 | HAMP domain-containing histidine kinase | - |
| EQB39_RS14985 () | 92516..93169 | - | 654 | WP_002285815.1 | Transcriptional regulatory protein QseB | VF |
| EQB39_RS14995 () | 93457..94731 | + | 1275 | WP_010729371.1 | ISL3 family transposase IS1476 | Transposase |
| EQB39_RS15000 () | 94786..96351 | + | 1566 | WP_032494987.1 | glutamine-hydrolyzing GMP synthase | - |
| EQB39_RS15005 () | 96771..97640 | - | 870 | WP_010729372.1 | ROK family protein | - |
| EQB39_RS15010 () | 97692..98684 | - | 993 | WP_010729373.1 | LacI family DNA-binding transcriptional regulator | - |
| EQB39_RS15015 () | 98861..100345 | - | 1485 | WP_010729374.1 | glycoside hydrolase family 32 protein | - |
| EQB39_RS15020 () | 100346..101953 | - | 1608 | WP_010729375.1 | ABC transporter substrate-binding protein | - |
| EQB39_RS15025 () | 102002..102886 | - | 885 | WP_005230433.1 | carbohydrate ABC transporter permease | - |
| EQB39_RS15030 () | 102902..103894 | - | 993 | WP_005233042.1 | sugar ABC transporter permease | - |
| EQB39_RS16275 () | 104518..104964 | - | 447 | WP_025481119.1 | hypothetical protein | - |
| EQB39_RS15040 () | 105559..105909 | + | 351 | WP_010729377.1 | hypothetical protein | - |
| EQB39_RS15045 () | 106114..106962 | + | 849 | WP_010729378.1 | rep protein | - |
| EQB39_RS15050 () | 107009..107203 | + | 195 | WP_002351139.1 | DUF3173 domain-containing protein | - |
| EQB39_RS15055 () | 107206..108408 | + | 1203 | WP_010729379.1 | site-specific integrase | - |
| EQB39_RS15060 () | 108634..108828 | + | 195 | WP_002285758.1 | hypothetical protein | - |
| EQB39_RS15065 () | 108818..109171 | + | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| EQB39_RS15070 () | 109273..110820 | + | 1548 | WP_002299190.1 | IS66 family transposase ISRob1 | Transposase |
| EQB39_RS15075 () | 111212..112144 | - | 933 | WP_002288609.1 | hypothetical protein | - |
| EQB39_RS15080 () | 112184..113845 | - | 1662 | WP_002288608.1 | hypothetical protein | VF |
| EQB39_RS15085 () | 113842..116823 | - | 2982 | WP_002305865.1 | glycoside hydrolase family 42 | - |
| EQB39_RS15090 () | 116951..118864 | - | 1914 | WP_002304880.1 | beta-N-acetylhexosaminidase | - |
| EQB39_RS15095 () | 118894..119505 | - | 612 | WP_002304878.1 | DUF624 domain-containing protein | - |
| EQB39_RS15100 () | 119556..121028 | - | 1473 | WP_010729380.1 | extracellular solute-binding protein | - |
| EQB39_RS15105 () | 121052..121963 | - | 912 | WP_002289655.1 | carbohydrate ABC transporter permease | - |
| EQB39_RS15110 () | 121975..122913 | - | 939 | WP_002304874.1 | sugar ABC transporter permease | - |
| EQB39_RS15115 () | 123142..124716 | + | 1575 | WP_002340467.1 | histidine kinase | - |
| EQB39_RS15120 () | 124694..125422 | + | 729 | WP_002302980.1 | helix-turn-helix domain-containing protein | - |
| EQB39_RS15125 () | 125805..127079 | - | 1275 | WP_010729381.1 | ISL3 family transposase IS1476 | Transposase |
| EQB39_RS15130 () | 127280..128494 | + | 1215 | Protein_126 | ISL3 family transposase ISEfa11 | Transposase |
| EQB39_RS15135 () | 128673..129002 | - | 330 | WP_002299919.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| EQB39_RS15140 () | 128992..129264 | - | 273 | WP_002299921.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| EQB39_RS15145 () | 129715..130518 | - | 804 | WP_002299923.1 | metallophosphoesterase | - |
| EQB39_RS15150 () | 130496..131620 | - | 1125 | WP_002299925.1 | Oligosaccharides import ATP-binding protein MsmX | VF |
| EQB39_RS15155 () | 131636..132451 | - | 816 | WP_002299926.1 | carbohydrate ABC transporter permease | - |
| EQB39_RS15160 () | 132441..133331 | - | 891 | WP_014748799.1 | sugar ABC transporter permease | - |
| EQB39_RS15165 () | 133398..134687 | - | 1290 | WP_002299928.1 | ABC transporter substrate-binding protein | - |
| EQB39_RS15170 () | 134915..135559 | - | 645 | Protein_134 | glycerophosphodiester phosphodiesterase | - |
| EQB39_RS15175 () | 136036..137514 | - | 1479 | WP_002389932.1 | IS1182 family transposase ISEfa7 | Transposase |
| EQB39_RS15180 () | 137504..138703 | - | 1200 | WP_010729384.1 | IS256 family transposase ISBsu2 | Transposase |
| EQB39_RS15185 () | 138833..140209 | - | 1377 | WP_002298085.1 | ABC transporter permease | - |
| EQB39_RS15190 () | 140209..140865 | - | 657 | WP_002298083.1 | putative ABC transporter ATP-binding protein | VF |
| EQB39_RS15195 () | 140875..142152 | - | 1278 | WP_002301194.1 | ABC transporter permease | - |
| EQB39_RS15200 () | 142171..142326 | - | 156 | Protein_140 | 4Fe-4S binding protein | - |
| EQB39_RS15205 () | 142402..143564 | + | 1163 | WP_087121905.1 | IS3 family transposase ISEfa8 | Transposase |
| EQB39_RS15210 () | 143594..144043 | - | 450 | WP_010729386.1 | TlpA family protein disulfide reductase | - |
| EQB39_RS16235 () | 144199..144741 | - | 543 | WP_002298088.1 | hypothetical protein | - |
| EQB39_RS15225 () | 145016..145659 | + | 644 | Protein_144 | transposase | - |
| EQB39_RS15230 () | 145735..146415 | + | 681 | WP_002331383.1 | IS6 family transposase IS1216E | Transposase |
| EQB39_RS15235 () | 146470..146826 | - | 357 | Protein_146 | hypothetical protein | - |
| EQB39_RS15240 () | 147086..147634 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EQB39_RS15245 () | 147635..148492 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EQB39_RS15250 () | 148778..149064 | - | 287 | Protein_149 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB39_RS15255 () | 149054..149383 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EQB39_RS15260 () | 149460..149732 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EQB39_RS15265 () | 149732..149995 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EQB39_RS15270 () | 150229..151137 | + | 909 | Protein_153 | IS982 family transposase ISEfm1 | Transposase |
| EQB39_RS15275 () | 151140..152315 | - | 1176 | WP_002336205.1 | MFS transporter | - |
| EQB39_RS15280 () | 152318..154567 | - | 2250 | WP_002314387.1 | alpha-galactosidase | - |
| EQB39_RS15285 () | 154664..155518 | - | 855 | WP_002338109.1 | AraC family transcriptional regulator | - |
| EQB39_RS15290 () | 155600..156508 | - | 909 | Protein_157 | IS982 family transposase ISEfm1 | Transposase |
| EQB39_RS15295 () | 156602..157537 | - | 936 | WP_002323400.1 | hypothetical protein | - |
| EQB39_RS15300 () | 158096..158413 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB39_RS15305 () | 158414..158668 | - | 255 | WP_002323399.1 | hypothetical protein | - |
| EQB39_RS15310 () | 159027..159431 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB39_RS15315 () | 159448..160596 | + | 1149 | WP_002323589.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB39_RS15320 () | 160819..161037 | - | 219 | Protein_163 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB39_RS15325 () | 161303..161497 | - | 195 | WP_002348857.1 | hypothetical protein | - |
| EQB39_RS15330 () | 161597..161683 | - | 87 | Protein_165 | single-stranded DNA-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|