MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 148571 bp
Accession: NZ_LR135259 Location: 1..148571 Organism: Enterococcus faecium isolate E4457 Replicon: plasmid 2
Accession: NZ_LR135259 Location: 1..148571 Organism: Enterococcus faecium isolate E4457 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQB59_RS13800 () | 1..1041 | + | 1041 | WP_002303636.1 | replication initiator protein A | - |
| EQB59_RS13805 () | 1302..2621 | + | 1320 | WP_000202380.1 | IS1380 family transposase IS1678 | Transposase |
| EQB59_RS13810 () | 3549..3881 | + | 333 | WP_002323647.1 | hypothetical protein | - |
| EQB59_RS13815 () | 4500..4841 | + | 342 | WP_002295674.1 | DUF5406 domain-containing protein | - |
| EQB59_RS13820 () | 4955..5194 | + | 240 | WP_002295673.1 | hypothetical protein | - |
| EQB59_RS13825 () | 5261..5497 | + | 237 | WP_002323648.1 | hypothetical protein | - |
| EQB59_RS13830 () | 5561..6516 | + | 956 | Protein_6 | IS30 family transposase | - |
| EQB59_RS13835 () | 6592..7263 | + | 672 | WP_002295671.1 | class A sortase | - |
| EQB59_RS13840 () | 7316..9291 | + | 1976 | Protein_8 | isopeptide-forming domain-containing fimbrial protein | - |
| EQB59_RS13845 () | 9306..10058 | + | 753 | WP_002293487.1 | Sortase A | VF |
| EQB59_RS13850 () | 10074..10835 | + | 762 | WP_002295669.1 | hypothetical protein | - |
| EQB59_RS13855 () | 10848..11108 | + | 261 | WP_002293489.1 | hypothetical protein | - |
| EQB59_RS13860 () | 11105..13195 | + | 2091 | WP_002326170.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EQB59_RS13865 () | 13222..13686 | + | 465 | WP_025477618.1 | hypothetical protein | - |
| EQB59_RS13870 () | 13683..13925 | + | 243 | WP_002305229.1 | DUF5415 family protein | - |
| EQB59_RS13875 () | 13943..14245 | + | 303 | WP_002295662.1 | hypothetical protein | - |
| EQB59_RS13880 () | 14315..16369 | + | 2055 | WP_002323241.1 | hypothetical protein | - |
| EQB59_RS13885 () | 16369..18981 | + | 2613 | WP_002305234.1 | type IV secretory system conjugative DNA transfer family protein | - |
| EQB59_RS13890 () | 18978..21374 | + | 2397 | WP_127836268.1 | hypothetical protein | - |
| EQB59_RS13895 () | 21426..21758 | + | 333 | WP_002295656.1 | hypothetical protein | - |
| EQB59_RS13900 () | 21759..22352 | + | 594 | WP_002305169.1 | hypothetical protein | - |
| EQB59_RS13905 () | 22518..23666 | - | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB59_RS13910 () | 23683..24087 | - | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB59_RS13915 () | 24268..24846 | + | 579 | WP_002311544.1 | hypothetical protein | - |
| EQB59_RS13920 () | 25016..27040 | + | 2025 | WP_002323680.1 | hypothetical protein | - |
| EQB59_RS13925 () | 27040..28245 | + | 1206 | WP_002323679.1 | glucosaminidase domain-containing protein | - |
| EQB59_RS13930 () | 28261..28905 | + | 645 | WP_002321287.1 | hypothetical protein | - |
| EQB59_RS13935 () | 28916..29722 | + | 807 | WP_002323678.1 | hypothetical protein | - |
| EQB59_RS13940 () | 29745..29975 | + | 231 | WP_002323677.1 | hypothetical protein | - |
| EQB59_RS13950 () | 30264..31426 | + | 1163 | WP_086956687.1 | IS3 family transposase IS1485 | Transposase |
| EQB59_RS13955 () | 31560..32492 | + | 933 | WP_002338120.1 | DUF4199 domain-containing protein | - |
| EQB59_RS13960 () | 32559..33518 | - | 960 | WP_002303350.1 | IS30 family transposase IS1062 | Transposase |
| EQB59_RS13965 () | 33614..34132 | + | 519 | Protein_32 | hypothetical protein | - |
| EQB59_RS13970 () | 34026..34295 | + | 270 | WP_025477911.1 | hypothetical protein | - |
| EQB59_RS13975 () | 34527..34823 | + | 297 | WP_002296377.1 | hypothetical protein | - |
| EQB59_RS13980 () | 34825..35247 | + | 423 | WP_002296378.1 | hypothetical protein | - |
| EQB59_RS13985 () | 35266..36858 | + | 1593 | WP_002296379.1 | hypothetical protein | Relaxase |
| EQB59_RS13990 () | 36879..37214 | + | 336 | WP_002296380.1 | hypothetical protein | - |
| EQB59_RS13995 () | 37360..37554 | + | 195 | WP_002322479.1 | hypothetical protein | - |
| EQB59_RS14000 () | 37690..38940 | - | 1251 | WP_002287107.1 | IS110 family transposase ISSpn10 | Transposase |
| EQB59_RS14005 () | 39350..41722 | + | 2373 | WP_002317424.1 | hypothetical protein | - |
| EQB59_RS14010 () | 41783..43252 | + | 1470 | WP_002313123.1 | toprim domain-containing protein | - |
| EQB59_RS14015 () | 43263..45467 | + | 2205 | WP_127837452.1 | type IA DNA topoisomerase | - |
| EQB59_RS15640 () | 45483..45632 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| EQB59_RS14020 () | 45713..46309 | + | 597 | WP_002322762.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EQB59_RS14025 () | 46322..47221 | + | 900 | WP_002322763.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EQB59_RS14030 () | 47224..47709 | + | 486 | WP_126309528.1 | single-stranded DNA-binding protein | - |
| EQB59_RS14035 () | 47731..47988 | + | 258 | WP_002322647.1 | hypothetical protein | - |
| EQB59_RS14040 () | 48147..48269 | - | 123 | WP_002295624.1 | putative holin-like toxin | - |
| EQB59_RS14045 () | 48423..48683 | + | 261 | WP_127837454.1 | hypothetical protein | - |
| EQB59_RS14050 () | 49132..49338 | + | 207 | WP_002296239.1 | hypothetical protein | - |
| EQB59_RS14055 () | 49338..49589 | + | 252 | WP_002287517.1 | hypothetical protein | - |
| EQB59_RS14060 () | 49605..50042 | + | 438 | WP_002326156.1 | hypothetical protein | - |
| EQB59_RS14065 () | 50035..50730 | + | 696 | WP_002305050.1 | hypothetical protein | - |
| EQB59_RS14075 () | 51352..51536 | + | 185 | Protein_54 | type II toxin-antitoxin system HicA family toxin | - |
| EQB59_RS14080 () | 51570..52001 | + | 432 | WP_002326154.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| EQB59_RS14085 () | 52527..53665 | - | 1139 | Protein_56 | transposase | - |
| EQB59_RS14100 () | 53682..54085 | - | 404 | Protein_57 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB59_RS14105 () | 54289..54906 | + | 618 | WP_002323453.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| EQB59_RS14110 () | 55283..56455 | - | 1173 | Protein_59 | IS256 family transposase | - |
| EQB59_RS14115 () | 56680..56964 | - | 285 | WP_085802738.1 | IS91 family transposase ISCARN110 | Transposase |
| EQB59_RS14120 () | 57036..57983 | - | 948 | Protein_61 | IS30 family transposase | - |
| EQB59_RS14125 () | 58080..58836 | - | 757 | Protein_62 | IS982 family transposase ISEfm1 | Transposase |
| EQB59_RS14130 () | 58947..59162 | + | 216 | Protein_63 | IS110 family transposase | - |
| EQB59_RS14135 () | 59288..60259 | + | 972 | WP_002347423.1 | LacI family DNA-binding transcriptional regulator | - |
| EQB59_RS14140 () | 60401..61714 | + | 1314 | WP_164856670.1 | sugar ABC transporter substrate-binding protein | - |
| EQB59_RS14145 () | 61757..62623 | + | 867 | WP_002371809.1 | sugar ABC transporter permease | - |
| EQB59_RS14150 () | 62620..63468 | + | 849 | WP_002347420.1 | carbohydrate ABC transporter permease | - |
| EQB59_RS14155 () | 63482..64954 | + | 1473 | WP_002347419.1 | glycoside hydrolase family 32 protein | - |
| EQB59_RS14160 () | 64971..65843 | + | 873 | WP_002347418.1 | ROK family protein | - |
| EQB59_RS14165 () | 66077..66462 | - | 386 | Protein_70 | IS3 family transposase IS1353 | Transposase |
| EQB59_RS14170 () | 66504..67543 | - | 1040 | Protein_71 | IS630 family transposase ISBs2 | Transposase |
| EQB59_RS14175 () | 67621..68609 | + | 989 | Protein_72 | IS3 family transposase ISKpn38 | Transposase |
| EQB59_RS14180 () | 68843..69715 | - | 873 | WP_002347415.1 | ROK family protein | - |
| EQB59_RS14185 () | 69979..71925 | - | 1947 | WP_002324510.1 | sucrose-specific PTS transporter subunit IIBC | - |
| EQB59_RS14190 () | 72110..73549 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
| EQB59_RS14195 () | 73551..74513 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| EQB59_RS14205 () | 76352..76807 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
| EQB59_RS14215 () | 77072..77170 | + | 99 | Protein_79 | IS30 family transposase | - |
| EQB59_RS14225 () | 77853..78671 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EQB59_RS14230 () | 78832..79521 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EQB59_RS14235 () | 79535..81037 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EQB59_RS14240 () | 81050..81526 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| EQB59_RS14260 () | 84304..84822 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EQB59_RS14270 () | 85959..86366 | - | 408 | WP_002297442.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| EQB59_RS14275 () | 86363..86596 | - | 234 | WP_002297441.1 | addiction module antitoxin | - |
| EQB59_RS14280 () | 86929..88014 | + | 1086 | WP_002297440.1 | tyrosine recombinase XerS | - |
| EQB59_RS14285 () | 88300..89478 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EQB59_RS14290 () | 89712..90602 | + | 891 | WP_002297439.1 | hypothetical protein | - |
| EQB59_RS14295 () | 91039..91593 | - | 555 | WP_002295761.1 | tyrosine-type recombinase/integrase | - |
| EQB59_RS14300 () | 92336..92896 | + | 561 | WP_002347210.1 | hypothetical protein | - |
| EQB59_RS14305 () | 92929..93741 | - | 813 | WP_002322679.1 | AAA family ATPase | - |
| EQB59_RS14310 () | 93734..95170 | - | 1437 | WP_002322678.1 | DDE-type integrase/transposase/recombinase | - |
| EQB59_RS14315 () | 95142..95735 | - | 594 | WP_002322677.1 | Tn3 family transposase TnBth3 | Transposase |
| EQB59_RS14320 () | 95967..96197 | + | 231 | WP_002322676.1 | hypothetical protein | Antitoxin Detail |
| EQB59_RS14325 () | 96197..96538 | + | 342 | WP_002322675.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| EQB59_RS14330 () | 96752..98254 | - | 1503 | WP_002322674.1 | xylulokinase | - |
| EQB59_RS14335 () | 98327..99379 | - | 1053 | WP_002323515.1 | sugar ABC transporter substrate-binding protein | - |
| EQB59_RS14340 () | 99432..100400 | - | 969 | WP_002322672.1 | ABC transporter permease | - |
| EQB59_RS14345 () | 100465..101973 | - | 1509 | WP_002322671.1 | sugar ABC transporter ATP-binding protein | - |
| EQB59_RS14350 () | 102023..103633 | - | 1611 | WP_002322670.1 | glycoside hydrolase family 43 protein | - |
| EQB59_RS14355 () | 103733..105040 | - | 1308 | WP_002322669.1 | xylose isomerase | - |
| EQB59_RS14360 () | 105301..106455 | + | 1155 | WP_002323041.1 | ROK family transcriptional regulator | - |
| EQB59_RS14365 () | 106981..107226 | + | 246 | WP_002323040.1 | hypothetical protein | - |
| EQB59_RS14370 () | 107223..107720 | - | 498 | WP_002316138.1 | Spermidine/spermine N(1)-acetyltransferase | VF |
| EQB59_RS14375 () | 107776..108681 | - | 906 | Protein_107 | IS982 family transposase | - |
| EQB59_RS14385 () | 109442..110622 | + | 1181 | Protein_108 | IS256 family transposase | - |
| EQB59_RS14390 () | 111440..111441 | - | 2 | WP_127837460.1 | IS6 family transposase ISS1W | Transposase |
| EQB59_RS14395 () | 111671..112996 | - | 1326 | WP_002347212.1 | cation transporter | - |
| EQB59_RS14400 () | 113024..113635 | - | 612 | WP_002322692.1 | CadD family cadmium resistance transporter | - |
| EQB59_RS14405 () | 113652..114017 | - | 366 | WP_002330544.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EQB59_RS14410 () | 114373..116277 | - | 1905 | WP_002322690.1 | heavy metal translocating P-type ATPase | - |
| EQB59_RS14415 () | 116475..116708 | - | 234 | WP_002301447.1 | cation transporter | - |
| EQB59_RS14420 () | 116855..117709 | - | 855 | WP_002322689.1 | prolipoprotein diacylglyceryl transferase | - |
| EQB59_RS14425 () | 117694..118032 | - | 339 | WP_002300938.1 | hypothetical protein | - |
| EQB59_RS14430 () | 118260..118964 | - | 705 | WP_002292156.1 | Crp/Fnr family transcriptional regulator | - |
| EQB59_RS14435 () | 119109..119681 | - | 573 | WP_002292150.1 | DNA protection during starvation protein | VF |
| EQB59_RS14445 () | 120236..121408 | + | 1173 | WP_002323279.1 | IS256 family transposase IS256 | Transposase |
| EQB59_RS14450 () | 121562..122092 | - | 531 | Protein_120 | IS982 family transposase ISEfm1 | Transposase |
| EQB59_RS14455 () | 122164..123456 | + | 1293 | WP_002298232.1 | ISL3 family transposase IS1251 | Transposase |
| EQB59_RS14460 () | 123668..124510 | - | 843 | WP_002289586.1 | PRD domain-containing protein | - |
| EQB59_RS14465 () | 124547..126013 | - | 1467 | WP_002289584.1 | glycoside hydrolase family 1 protein | - |
| EQB59_RS14470 () | 126069..127913 | - | 1845 | WP_002298230.1 | beta-glucoside-specific PTS transporter subunit IIABC | - |
| EQB59_RS14475 () | 128515..129465 | + | 951 | WP_002300609.1 | Transcriptional regulatory protein DagR | VF |
| EQB59_RS14480 () | 129510..130143 | - | 634 | Protein_126 | peptidase | - |
| EQB59_RS14485 () | 130403..130951 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EQB59_RS14490 () | 130952..131809 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EQB59_RS14495 () | 131982..133160 | - | 1179 | WP_002324322.1 | IS256 family transposase ISEfm2 | Transposase |
| EQB59_RS14500 () | 133428..133715 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB59_RS14505 () | 133705..134034 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EQB59_RS14510 () | 134111..134383 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EQB59_RS14515 () | 134383..134646 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EQB59_RS14520 () | 134880..135788 | + | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EQB59_RS14525 () | 135791..136966 | - | 1176 | WP_002323312.1 | MFS transporter | - |
| EQB59_RS14530 () | 136969..139218 | - | 2250 | WP_002323313.1 | alpha-galactosidase | - |
| EQB59_RS14535 () | 139315..140169 | - | 855 | WP_002317112.1 | AraC family transcriptional regulator | - |
| EQB59_RS14540 () | 140256..141164 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EQB59_RS14545 () | 141258..142193 | - | 936 | WP_002323400.1 | hypothetical protein | - |
| EQB59_RS14550 () | 142752..143069 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB59_RS14555 () | 143070..143324 | - | 255 | WP_002323399.1 | hypothetical protein | - |
| EQB59_RS14560 () | 143683..144087 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB59_RS14565 () | 144104..145252 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB59_RS14570 () | 145475..145693 | - | 219 | Protein_144 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB59_RS14575 () | 145959..146153 | - | 195 | WP_002348857.1 | hypothetical protein | - |
| EQB59_RS14580 () | 146253..146339 | - | 87 | Protein_146 | single-stranded DNA-binding protein | - |
| EQB59_RS14585 () | 146832..147785 | + | 954 | WP_002325884.1 | IS30 family transposase IS1252 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|