MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 167526 bp
Accession: NZ_LR135182 Location: 1..167526 Organism: Enterococcus faecium isolate E1774 Replicon: plasmid 2
Accession: NZ_LR135182 Location: 1..167526 Organism: Enterococcus faecium isolate E1774 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL353_RS13740 () | 1..1041 | + | 1041 | WP_002303636.1 | replication initiator protein A | - |
| EL353_RS13745 () | 1865..2197 | + | 333 | WP_002322486.1 | hypothetical protein | - |
| EL353_RS13750 () | 2816..3157 | + | 342 | WP_002311521.1 | DUF5406 domain-containing protein | - |
| EL353_RS13755 () | 3176..3466 | + | 291 | WP_002311523.1 | hypothetical protein | - |
| EL353_RS13760 () | 3781..5031 | - | 1251 | WP_002287107.1 | IS110 family transposase ISSpn10 | Transposase |
| EL353_RS13765 () | 5441..7813 | + | 2373 | WP_002317424.1 | hypothetical protein | - |
| EL353_RS13770 () | 7874..9343 | + | 1470 | WP_002313123.1 | toprim domain-containing protein | - |
| EL353_RS13775 () | 9354..11363 | + | 2010 | WP_002303486.1 | DNA topoisomerase III | - |
| EL353_RS15100 () | 11479..11628 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| EL353_RS13785 () | 11709..12305 | + | 597 | WP_002299811.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EL353_RS13790 () | 12318..13217 | + | 900 | WP_002352365.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EL353_RS13795 () | 13220..13351 | + | 132 | WP_002301801.1 | single-stranded DNA-binding protein | - |
| EL353_RS13800 () | 13373..13705 | + | 333 | WP_002305808.1 | single-stranded DNA-binding protein | - |
| EL353_RS13805 () | 13750..13983 | + | 234 | WP_002303482.1 | hypothetical protein | - |
| EL353_RS13810 () | 14142..14264 | - | 123 | WP_002295624.1 | putative holin-like toxin | - |
| EL353_RS13815 () | 14454..14678 | + | 225 | WP_002305809.1 | hypothetical protein | - |
| EL353_RS13825 () | 15121..15327 | + | 207 | WP_002305810.1 | hypothetical protein | - |
| EL353_RS13830 () | 15327..15578 | + | 252 | WP_002300797.1 | hypothetical protein | - |
| EL353_RS15105 () | 15594..15749 | + | 156 | WP_002300799.1 | hypothetical protein | - |
| EL353_RS13835 () | 15759..16031 | + | 273 | WP_002300801.1 | hypothetical protein | - |
| EL353_RS13845 () | 16476..16655 | + | 180 | WP_002300804.1 | hypothetical protein | - |
| EL353_RS13850 () | 16714..17070 | + | 357 | WP_002311569.1 | hypothetical protein | - |
| EL353_RS13860 () | 18039..18987 | - | 949 | Protein_22 | IS30 family transposase | - |
| EL353_RS13865 () | 19108..19371 | + | 264 | WP_002300807.1 | uberolysin/carnocyclin family circular bacteriocin | - |
| EL353_RS13875 () | 19743..20918 | + | 1176 | Protein_24 | IS256 family transposase | - |
| EL353_RS13880 () | 21306..23252 | + | 1947 | WP_002300833.1 | PTS sugar transporter subunit IIA | - |
| EL353_RS13885 () | 23255..23710 | + | 456 | WP_002300835.1 | PTS sugar transporter subunit IIA | - |
| EL353_RS13890 () | 23724..25052 | + | 1329 | WP_002300836.1 | PTS galactitol transporter subunit IIC | - |
| EL353_RS13895 () | 25086..25370 | + | 285 | WP_002300838.1 | PTS sugar transporter subunit IIB | - |
| EL353_RS13900 () | 25372..25887 | + | 516 | WP_002300840.1 | YjbQ family protein | - |
| EL353_RS13905 () | 25903..26565 | + | 663 | WP_002300841.1 | Ribulose-phosphate 3-epimerase | VF |
| EL353_RS13910 () | 26572..27144 | + | 573 | WP_002300842.1 | 3-hexulose-6-phosphate isomerase | VF |
| EL353_RS13915 () | 27331..28851 | - | 1521 | WP_002300843.1 | IS66 family transposase ISDeal1 | Transposase |
| EL353_RS13920 () | 29094..29279 | - | 186 | WP_002305884.1 | IS66 family transposase ISEbi1 | Transposase |
| EL353_RS13925 () | 29263..29445 | - | 183 | WP_002300846.1 | hypothetical protein | - |
| EL353_RS13930 () | 29686..29904 | + | 219 | Protein_35 | IS256 family transposase ISLgar5 | Transposase |
| EL353_RS13935 () | 30399..30998 | + | 600 | WP_002301839.1 | Tyrosine recombinase XerC | VF |
| EL353_RS13940 () | 31062..31661 | + | 600 | WP_002322465.1 | bacteriophage abortive infection AbiH family protein | - |
| EL353_RS13945 () | 31691..32342 | - | 652 | Protein_38 | IS6 family transposase IS1216V | Transposase |
| EL353_RS13950 () | 32677..33549 | - | 873 | WP_002305879.1 | ROK family protein | - |
| EL353_RS13955 () | 33813..35759 | - | 1947 | WP_002352509.1 | sucrose-specific PTS transporter subunit IIBC | - |
| EL353_RS13960 () | 35944..37383 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
| EL353_RS13965 () | 37385..38347 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| EL353_RS13975 () | 40186..40641 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
| EL353_RS13985 () | 40906..41004 | + | 99 | Protein_45 | IS30 family transposase | - |
| EL353_RS13990 () | 41227..41457 | - | 231 | WP_002289255.1 | resolvase | - |
| EL353_RS13995 () | 41687..42505 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EL353_RS14000 () | 42666..43355 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EL353_RS14005 () | 43369..44871 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EL353_RS14010 () | 44884..45360 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| EL353_RS14015 () | 45457..45633 | - | 177 | WP_158514236.1 | transposase | - |
| EL353_RS14035 () | 48138..48656 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EL353_RS14045 () | 50055..51602 | - | 1548 | WP_002296127.1 | IS66 family transposase ISRob1 | Transposase |
| EL353_RS14050 () | 51704..52057 | - | 354 | WP_002287659.1 | IS66 family transposase ISDeal1 | Transposase |
| EL353_RS14055 () | 52047..52241 | - | 195 | WP_002285758.1 | hypothetical protein | - |
| EL353_RS14065 () | 53085..54170 | + | 1086 | WP_002301591.1 | tyrosine recombinase XerS | - |
| EL353_RS14070 () | 54278..55231 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
| EL353_RS14075 () | 55362..56612 | - | 1251 | WP_002301126.1 | PTS sugar transporter subunit IIC | - |
| EL353_RS14080 () | 56631..57557 | - | 927 | WP_002298736.1 | PEP phosphonomutase | - |
| EL353_RS14085 () | 57636..58631 | - | 996 | WP_002301128.1 | tagatose-bisphosphate aldolase | - |
| EL353_RS14090 () | 58647..59816 | - | 1170 | WP_002301130.1 | SIS domain-containing protein | - |
| EL353_RS14095 () | 59832..60566 | - | 735 | WP_002301131.1 | GntR family transcriptional regulator | - |
| EL353_RS14105 () | 62758..64097 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| EL353_RS14110 () | 64488..65780 | - | 1293 | WP_002301811.1 | IS256 family transposase ISBsu2 | Transposase |
| EL353_RS14115 () | 66054..66314 | - | 261 | WP_002313174.1 | hypothetical protein | - |
| EL353_RS14120 () | 66565..67743 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EL353_RS14125 () | 68095..68391 | + | 297 | WP_073120200.1 | IS3 family transposase | - |
| EL353_RS14130 () | 68314..69194 | - | 881 | Protein_70 | IS3 family transposase ISEfa8 | Transposase |
| EL353_RS14135 () | 69396..69791 | - | 396 | WP_002287876.1 | aspartate 1-decarboxylase | - |
| EL353_RS14140 () | 69801..70649 | - | 849 | WP_002287875.1 | pantoate--beta-alanine ligase | - |
| EL353_RS14145 () | 70664..71491 | - | 828 | WP_002287874.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| EL353_RS14150 () | 71503..72363 | - | 861 | WP_002349114.1 | Rossmann-like and DUF2520 domain-containing protein | - |
| EL353_RS14155 () | 72601..73770 | + | 1170 | WP_002300493.1 | IS256 family transposase ISEfa13 | Transposase |
| EL353_RS14160 () | 74095..75414 | - | 1320 | WP_002300494.1 | HAMP domain-containing histidine kinase | - |
| EL353_RS14165 () | 75411..76064 | - | 654 | WP_002285815.1 | Transcriptional regulatory protein QseB | VF |
| EL353_RS14175 () | 76352..77285 | + | 934 | Protein_78 | ISL3 family transposase IS1476 | Transposase |
| EL353_RS14180 () | 77193..77909 | - | 717 | WP_002348630.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| EL353_RS14185 () | 77959..78168 | - | 210 | WP_002302256.1 | hypothetical protein | - |
| EL353_RS14190 () | 78445..79718 | + | 1274 | Protein_81 | ISL3 family transposase ISEfa11 | Transposase |
| EL353_RS14195 () | 79825..80856 | - | 1032 | WP_002302261.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| EL353_RS14200 () | 80863..81693 | - | 831 | WP_002313180.1 | ABC transporter permease | - |
| EL353_RS14205 () | 81690..82505 | - | 816 | WP_002330693.1 | ABC transporter permease subunit | - |
| EL353_RS14210 () | 82502..83326 | - | 825 | WP_002302267.1 | alkaline phosphatase family protein | - |
| EL353_RS14215 () | 83316..84416 | - | 1101 | WP_002302268.1 | extracellular solute-binding protein | - |
| EL353_RS14220 () | 84594..85379 | + | 786 | WP_002302270.1 | histidinol phosphate phosphatase | - |
| EL353_RS14225 () | 85412..85795 | + | 384 | WP_002330694.1 | hypothetical protein | - |
| EL353_RS14230 () | 85871..86002 | + | 132 | WP_077828694.1 | peptidylprolyl isomerase | - |
| EL353_RS14235 () | 85971..86207 | + | 237 | WP_002322470.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase | VF |
| EL353_RS14240 () | 86219..86386 | + | 168 | WP_077828693.1 | peptidylprolyl isomerase | - |
| EL353_RS14250 () | 86508..87803 | - | 1296 | WP_002296623.1 | ISL3 family transposase IS1251 | Transposase |
| EL353_RS14255 () | 87925..88767 | - | 843 | Protein_93 | radical SAM protein | - |
| EL353_RS14260 () | 89419..91041 | + | 1623 | WP_126355946.1 | IS1182 family transposase ISEfa7 | Transposase |
| EL353_RS14265 () | 91327..92703 | - | 1377 | WP_002301195.1 | ABC transporter permease | - |
| EL353_RS14270 () | 92703..93359 | - | 657 | WP_002298083.1 | putative ABC transporter ATP-binding protein | VF |
| EL353_RS14275 () | 93369..94646 | - | 1278 | WP_002301194.1 | ABC transporter permease | - |
| EL353_RS14280 () | 94665..94820 | - | 156 | Protein_98 | 4Fe-4S binding protein | - |
| EL353_RS14285 () | 94896..96058 | + | 1163 | WP_087121905.1 | IS3 family transposase ISEfa8 | Transposase |
| EL353_RS14290 () | 96088..96537 | - | 450 | WP_002330699.1 | TlpA family protein disulfide reductase | - |
| EL353_RS15110 () | 96693..97235 | - | 543 | WP_002298088.1 | hypothetical protein | - |
| EL353_RS14305 () | 97463..98625 | + | 1163 | WP_114366812.1 | IS3 family transposase ISEfa8 | Transposase |
| EL353_RS14315 () | 98731..98946 | + | 216 | Protein_103 | IS256 family transposase ISEf1 | Transposase |
| EL353_RS14320 () | 99237..99716 | - | 480 | WP_010733565.1 | hypothetical protein | - |
| EL353_RS14325 () | 99786..100694 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EL353_RS15115 () | 100805..101116 | - | 312 | Protein_106 | hypothetical protein | - |
| EL353_RS14335 () | 101370..101924 | - | 555 | WP_002301108.1 | tyrosine-type recombinase/integrase | - |
| EL353_RS14340 () | 102395..103585 | - | 1191 | WP_102829669.1 | IS256 family transposase ISLgar5 | Transposase |
| EL353_RS14350 () | 104593..105210 | - | 618 | WP_002376250.1 | hypothetical protein | - |
| EL353_RS14355 () | 105272..105952 | - | 681 | Protein_110 | IS6 family transposase IS1297 | Transposase |
| EL353_RS14365 () | 106219..106767 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EL353_RS14370 () | 106768..107625 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EL353_RS14375 () | 107911..108198 | - | 288 | WP_002345819.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL353_RS14380 () | 108188..108517 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EL353_RS14385 () | 108594..108866 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EL353_RS14390 () | 108866..109129 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EL353_RS14395 () | 109235..109612 | - | 378 | WP_061343365.1 | hypothetical protein | - |
| EL353_RS14400 () | 109975..110934 | - | 960 | WP_002301399.1 | IS30 family transposase IS1062 | Transposase |
| EL353_RS14405 () | 111029..111226 | - | 198 | Protein_119 | hypothetical protein | - |
| EL353_RS14410 () | 111688..112368 | - | 681 | WP_002331383.1 | IS6 family transposase IS1216E | Transposase |
| EL353_RS14415 () | 112444..112638 | - | 195 | Protein_121 | IS3 family transposase IS1485 | Transposase |
| EL353_RS14420 () | 112715..112924 | + | 210 | Protein_122 | ATP-dependent protease | - |
| EL353_RS14425 () | 113122..113718 | - | 597 | WP_080251180.1 | YdhK family protein | - |
| EL353_RS14430 () | 113739..113945 | - | 207 | WP_002307659.1 | hypothetical protein | - |
| EL353_RS14435 () | 113960..115354 | - | 1395 | WP_002294791.1 | HAMP domain-containing histidine kinase | - |
| EL353_RS14440 () | 115354..116034 | - | 681 | WP_002294790.1 | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | VF |
| EL353_RS14445 () | 116062..117645 | - | 1584 | WP_002371871.1 | multicopper oxidase domain-containing protein | - |
| EL353_RS14450 () | 117656..117880 | - | 225 | WP_002328846.1 | heavy-metal-associated domain-containing protein | - |
| EL353_RS14455 () | 118522..118731 | - | 210 | WP_002307655.1 | heavy-metal-associated domain-containing protein | - |
| EL353_RS14460 () | 118748..121198 | - | 2451 | WP_023042780.1 | heavy metal translocating P-type ATPase | - |
| EL353_RS14465 () | 121182..121547 | - | 366 | WP_033700481.1 | BlaI/MecI/CopY family transcriptional regulator | - |
| EL353_RS14470 () | 121563..122177 | - | 615 | WP_002319974.1 | TIGR01906 family membrane protein | - |
| EL353_RS14475 () | 122333..123136 | + | 804 | WP_002294779.1 | prolipoprotein diacylglyceryl transferase | - |
| EL353_RS14480 () | 123120..123344 | + | 225 | WP_002307648.1 | DUF2933 domain-containing protein | - |
| EL353_RS14485 () | 123347..123526 | + | 180 | WP_002325573.1 | DUF2933 domain-containing protein | - |
| EL353_RS14490 () | 123640..125190 | - | 1551 | Protein_136 | IS1182 family transposase | - |
| EL353_RS14495 () | 125901..127184 | - | 1284 | WP_002325571.1 | hypothetical protein | - |
| EL353_RS14500 () | 127363..127770 | - | 408 | WP_023042782.1 | NusG domain II-containing protein | - |
| EL353_RS14505 () | 128042..129541 | + | 1500 | WP_002294768.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| EL353_RS14510 () | 129544..130232 | + | 689 | Protein_140 | Sortase A | VF |
| EL353_RS14520 () | 130770..131066 | - | 297 | WP_033604467.1 | hypothetical protein | - |
| EL353_RS14525 () | 131148..131414 | - | 267 | WP_002307629.1 | YfhO family protein | - |
| EL353_RS14535 () | 132992..133267 | + | 276 | WP_002322511.1 | hypothetical protein | - |
| EL353_RS14540 () | 133413..134798 | - | 1386 | WP_002317307.1 | PTS transporter subunit EIIC | - |
| EL353_RS14545 () | 134811..136151 | - | 1341 | WP_002352481.1 | glycoside hydrolase family 32 protein | - |
| EL353_RS14550 () | 136305..137159 | + | 855 | WP_002322539.1 | AraC family transcriptional regulator | - |
| EL353_RS14555 () | 137234..139354 | + | 2121 | WP_002302038.1 | alpha-galactosidase | - |
| EL353_RS14560 () | 139347..139811 | + | 465 | WP_002317311.1 | PTS glucose transporter subunit IIA | - |
| EL353_RS14570 () | 141795..142337 | - | 543 | WP_002301358.1 | hypothetical protein | - |
| EL353_RS14575 () | 142650..143201 | - | 552 | Protein_152 | tyrosine-type recombinase/integrase | - |
| EL353_RS14580 () | 143441..144058 | - | 618 | WP_002319351.1 | CadD family cadmium resistance transporter | - |
| EL353_RS14585 () | 144075..144437 | - | 363 | WP_002300950.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EL353_RS14590 () | 144621..145580 | - | 960 | WP_002311774.1 | IS30 family transposase IS1062 | Transposase |
| EL353_RS14595 () | 145812..147716 | - | 1905 | WP_002307621.1 | heavy metal translocating P-type ATPase | - |
| EL353_RS14600 () | 147914..148147 | - | 234 | WP_002292161.1 | cation transporter | - |
| EL353_RS14605 () | 148294..148584 | - | 291 | WP_073438625.1 | prolipoprotein diacylglyceryl transferase | - |
| EL353_RS14610 () | 148611..149315 | - | 705 | WP_002292156.1 | Crp/Fnr family transcriptional regulator | - |
| EL353_RS14615 () | 149460..150032 | - | 573 | WP_002292150.1 | DNA protection during starvation protein | VF |
| EL353_RS14620 () | 150568..151758 | - | 1191 | WP_102829667.1 | IS256 family transposase ISLgar5 | Transposase |
| EL353_RS14625 () | 152499..152858 | + | 360 | WP_002303333.1 | iron-sulfur cluster biosynthesis family protein | - |
| EL353_RS14630 () | 152931..153749 | - | 819 | WP_002303335.1 | Cof-type HAD-IIB family hydrolase | - |
| EL353_RS14635 () | 154163..154594 | - | 432 | WP_002293556.1 | GNAT family N-acetyltransferase | - |
| EL353_RS14640 () | 154695..154994 | + | 300 | WP_002352431.1 | hypothetical protein | - |
| EL353_RS14645 () | 155039..155689 | - | 651 | WP_002332339.1 | aspartate/glutamate racemase family protein | - |
| EL353_RS14650 () | 156558..157853 | - | 1296 | Protein_167 | ISL3 family transposase ISEfa11 | Transposase |
| EL353_RS14655 () | 158039..158431 | - | 393 | WP_002307605.1 | OsmC family protein | - |
| EL353_RS14660 () | 158428..159318 | - | 891 | WP_002352386.1 | ABC transporter ATP-binding protein | - |
| EL353_RS14665 () | 159318..159794 | - | 477 | Protein_170 | Vitamin B12 import ATP-binding protein BtuD | VF |
| EL353_RS14670 () | 159854..160528 | - | 675 | WP_002333342.1 | IS6 family transposase IS1297 | Transposase |
| EL353_RS14675 () | 160730..161134 | - | 405 | WP_002314381.1 | DUF4430 domain-containing protein | - |
| EL353_RS14680 () | 161150..161719 | - | 570 | WP_002352383.1 | cob(I)yrinic acid a,c-diamide adenosyltransferase | - |
| EL353_RS14685 () | 161733..163481 | - | 1749 | Protein_174 | vitamin B12-dependent ribonucleotide reductase | - |
| EL353_RS14690 () | 163535..164215 | - | 681 | WP_161544171.1 | IS6 family transposase IS1216E | Transposase |
| EL353_RS14695 () | 164666..164983 | - | 318 | WP_002352476.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL353_RS14700 () | 164984..165238 | - | 255 | WP_002290397.1 | AbrB family transcriptional regulator | - |
| EL353_RS14705 () | 165498..165716 | - | 219 | Protein_178 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL353_RS14710 () | 166275..166361 | - | 87 | Protein_179 | single-stranded DNA-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|