MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 139885 bp
Accession: NZ_LR135180 Location: 1..139885 Organism: Enterococcus faecium isolate E0595 Replicon: plasmid 2
Accession: NZ_LR135180 Location: 1..139885 Organism: Enterococcus faecium isolate E0595 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL352_RS12510 () | 1..1041 | + | 1041 | WP_002325563.1 | replication initiator protein A | - |
| EL352_RS12515 () | 1880..2212 | + | 333 | WP_002322486.1 | hypothetical protein | - |
| EL352_RS12520 () | 2830..3171 | + | 342 | WP_002325562.1 | DUF5406 domain-containing protein | - |
| EL352_RS12525 () | 3190..3480 | + | 291 | WP_002311523.1 | hypothetical protein | - |
| EL352_RS12530 () | 3672..3905 | + | 234 | WP_002311524.1 | hypothetical protein | - |
| EL352_RS12535 () | 3972..4211 | + | 240 | WP_002313093.1 | hypothetical protein | - |
| EL352_RS12540 () | 4297..4968 | + | 672 | WP_002311526.1 | class A sortase | - |
| EL352_RS12545 () | 5021..6997 | + | 1977 | WP_002325561.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EL352_RS12550 () | 7010..7642 | + | 633 | Protein_8 | hypothetical protein | VF |
| EL352_RS12555 () | 7763..8590 | + | 828 | WP_002332272.1 | hypothetical protein | VF |
| EL352_RS12560 () | 8600..8848 | + | 249 | WP_002325559.1 | hypothetical protein | - |
| EL352_RS12565 () | 8891..10990 | + | 2100 | WP_002325558.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EL352_RS12570 () | 11028..13079 | - | 2052 | WP_002325557.1 | hypothetical protein | VF |
| EL352_RS12580 () | 13437..13637 | + | 201 | WP_002325556.1 | DUF5415 family protein | - |
| EL352_RS12585 () | 13655..13957 | + | 303 | WP_002295662.1 | hypothetical protein | - |
| EL352_RS12590 () | 14027..16090 | + | 2064 | WP_002325555.1 | hypothetical protein | - |
| EL352_RS12595 () | 16090..18702 | + | 2613 | WP_002325554.1 | type IV secretory system conjugative DNA transfer family protein | - |
| EL352_RS12600 () | 18699..21077 | + | 2379 | WP_002325553.1 | hypothetical protein | - |
| EL352_RS12605 () | 21129..21461 | + | 333 | WP_002325552.1 | hypothetical protein | - |
| EL352_RS12610 () | 21462..22055 | + | 594 | WP_002320584.1 | hypothetical protein | - |
| EL352_RS12615 () | 22218..24242 | + | 2025 | WP_002325551.1 | ATPase | - |
| EL352_RS12620 () | 24242..25447 | + | 1206 | WP_002325550.1 | glucosaminidase domain-containing protein | - |
| EL352_RS12625 () | 25463..26107 | + | 645 | WP_002325549.1 | hypothetical protein | - |
| EL352_RS12630 () | 26118..26924 | + | 807 | WP_002325548.1 | hypothetical protein | - |
| EL352_RS12635 () | 26947..27177 | + | 231 | WP_002304981.1 | hypothetical protein | - |
| EL352_RS12640 () | 27724..27999 | + | 276 | WP_002325546.1 | hypothetical protein | - |
| EL352_RS12645 () | 28041..28463 | + | 423 | WP_002302844.1 | hypothetical protein | - |
| EL352_RS12650 () | 28483..30075 | + | 1593 | WP_033582043.1 | hypothetical protein | Relaxase |
| EL352_RS12655 () | 30096..30431 | + | 336 | WP_002310991.1 | hypothetical protein | - |
| EL352_RS12660 () | 30577..30771 | + | 195 | WP_002302840.1 | hypothetical protein | - |
| EL352_RS12665 () | 30784..33156 | + | 2373 | WP_002325544.1 | hypothetical protein | - |
| EL352_RS12670 () | 33217..34677 | + | 1461 | WP_002325543.1 | toprim domain-containing protein | - |
| EL352_RS12675 () | 34688..36892 | + | 2205 | WP_025479250.1 | type IA DNA topoisomerase | - |
| EL352_RS13430 () | 36908..37057 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| EL352_RS12680 () | 37138..37734 | + | 597 | WP_002325541.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EL352_RS12685 () | 37747..38646 | + | 900 | WP_002325540.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EL352_RS12690 () | 38649..39134 | + | 486 | WP_002325539.1 | single-stranded DNA-binding protein | - |
| EL352_RS12695 () | 39500..39760 | + | 261 | WP_002325538.1 | hypothetical protein | - |
| EL352_RS12700 () | 40205..40411 | + | 207 | WP_002325537.1 | hypothetical protein | - |
| EL352_RS12705 () | 40411..40662 | + | 252 | WP_002320549.1 | hypothetical protein | - |
| EL352_RS12710 () | 40678..41115 | + | 438 | WP_010721118.1 | hypothetical protein | - |
| EL352_RS12715 () | 41108..41815 | + | 708 | WP_002325535.1 | hypothetical protein | - |
| EL352_RS12725 () | 42196..42375 | + | 180 | WP_002325533.1 | hypothetical protein | - |
| EL352_RS12730 () | 42648..43142 | - | 495 | WP_002325532.1 | hypothetical protein | - |
| EL352_RS12735 () | 43303..43740 | + | 438 | WP_002325531.1 | response regulator transcription factor | - |
| EL352_RS12740 () | 43769..44557 | + | 789 | WP_002325530.1 | hypothetical protein | - |
| EL352_RS13435 () | 44667..44837 | + | 171 | WP_172599325.1 | hypothetical protein | - |
| EL352_RS12745 () | 44851..45468 | + | 618 | WP_058138117.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| EL352_RS12750 () | 45468..45830 | + | 363 | WP_126347910.1 | topoisomerase | - |
| EL352_RS12755 () | 46567..48453 | + | 1887 | WP_002295588.1 | group II intron reverse transcriptase/maturase | - |
| EL352_RS12760 () | 48706..50382 | + | 1677 | WP_126347913.1 | type IA DNA topoisomerase | - |
| EL352_RS12765 () | 50464..51360 | + | 897 | WP_002333001.1 | ParA family protein | - |
| EL352_RS12770 () | 51458..51667 | + | 210 | WP_000527318.1 | peptide-binding protein | - |
| EL352_RS12775 () | 51685..51957 | + | 273 | WP_126347911.1 | antitoxin | Antitoxin Detail |
| EL352_RS12780 () | 51959..52822 | + | 864 | WP_084679662.1 | zeta toxin family protein | Toxin Detail |
| EL352_RS12785 () | 52944..53441 | + | 498 | WP_096710545.1 | molecular chaperone DnaJ | - |
| EL352_RS12790 () | 53526..54122 | - | 597 | WP_002326773.1 | TetR/AcrR family transcriptional regulator | - |
| EL352_RS12795 () | 54434..55315 | + | 882 | WP_074626908.1 | Multidrug efflux system ATP-binding protein | VF |
| EL352_RS12800 () | 55339..56952 | + | 1614 | WP_126347912.1 | tetronasin resistance protein | - |
| EL352_RS12805 () | 57024..57536 | - | 513 | Protein_59 | IS30 family transposase ISApl1 | Transposase |
| EL352_RS13455 () | 57594..57712 | + | 119 | Protein_60 | zeta toxin | - |
| EL352_RS12815 () | 57798..57914 | + | 117 | WP_113998176.1 | zeta-toxin | - |
| EL352_RS12820 () | 58177..58914 | - | 738 | WP_001038795.1 | rRNA adenine N-6-methyltransferase | ARG |
| EL352_RS12825 () | 59039..59122 | - | 84 | WP_031929417.1 | 23S rRNA methyltransferase attenuator leader peptide ErmL | - |
| EL352_RS12835 () | 59903..60400 | + | 498 | WP_002325587.1 | hypothetical protein | - |
| EL352_RS12840 () | 60434..60706 | + | 273 | WP_002325586.1 | hypothetical protein | - |
| EL352_RS12845 () | 60736..61416 | - | 681 | WP_002325565.1 | IS6 family transposase IS1216E | Transposase |
| EL352_RS12855 () | 61845..62267 | + | 423 | WP_002307506.1 | cupin domain-containing protein | - |
| EL352_RS12860 () | 62351..63004 | + | 654 | WP_002307505.1 | putative iron export ATP-binding protein FetA | VF |
| EL352_RS12865 () | 63001..63765 | + | 765 | WP_002311027.1 | iron export ABC transporter permease subunit FetB | - |
| EL352_RS12870 () | 64219..65381 | + | 1163 | WP_126333308.1 | IS3 family transposase IS1485 | Transposase |
| EL352_RS12875 () | 65766..66173 | - | 408 | WP_002307501.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| EL352_RS12880 () | 66170..66403 | - | 234 | WP_002295764.1 | addiction module antitoxin | - |
| EL352_RS12885 () | 66725..67810 | + | 1086 | WP_002295762.1 | tyrosine recombinase XerS | - |
| EL352_RS12890 () | 67873..68427 | - | 555 | WP_002318477.1 | tyrosine-type recombinase/integrase | - |
| EL352_RS12895 () | 69170..69865 | + | 696 | WP_002325581.1 | histidinol phosphate phosphatase HisJ family protein | - |
| EL352_RS12900 () | 69902..70399 | - | 498 | WP_002308046.1 | Spermidine/spermine N(1)-acetyltransferase | VF |
| EL352_RS12905 () | 70455..71363 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EL352_RS12915 () | 72188..72790 | - | 603 | WP_079996756.1 | hypothetical protein | - |
| EL352_RS12920 () | 72919..73599 | - | 681 | WP_002332992.1 | IS6 family transposase IS1297 | Transposase |
| EL352_RS12930 () | 74130..74975 | - | 846 | Protein_80 | prolipoprotein diacylglyceryl transferase | - |
| EL352_RS12935 () | 75047..75667 | - | 621 | WP_002294569.1 | adenylate kinase | - |
| EL352_RS12940 () | 75799..77931 | - | 2133 | WP_002294570.1 | Copper-exporting P-type ATPase B | VF |
| EL352_RS12945 () | 78069..78275 | - | 207 | WP_002294571.1 | copper chaperone TcrZ | - |
| EL352_RS12950 () | 78361..80826 | - | 2466 | WP_002294572.1 | heavy metal translocating P-type ATPase | - |
| EL352_RS12955 () | 80839..81294 | - | 456 | WP_002294574.1 | copper-responsive transcriptional repressor TcrY | - |
| EL352_RS12960 () | 82093..82626 | - | 534 | Protein_86 | IS6 family transposase IS1297 | Transposase |
| EL352_RS12970 () | 82733..83698 | + | 966 | WP_002325577.1 | putative copper-transporting ATPase PacS | VF |
| EL352_RS12975 () | 83978..85279 | + | 1302 | Protein_88 | ISL3 family transposase IS1476 | Transposase |
| EL352_RS12980 () | 85477..86073 | - | 597 | WP_032495002.1 | YdhK family protein | - |
| EL352_RS12985 () | 86094..86300 | - | 207 | WP_002307659.1 | hypothetical protein | - |
| EL352_RS12990 () | 86315..87709 | - | 1395 | WP_002294791.1 | HAMP domain-containing histidine kinase | - |
| EL352_RS12995 () | 87709..88389 | - | 681 | WP_002294790.1 | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | VF |
| EL352_RS13000 () | 88417..90000 | - | 1584 | WP_032495004.1 | multicopper oxidase domain-containing protein | - |
| EL352_RS13005 () | 90011..90235 | - | 225 | WP_002294786.1 | heavy-metal-associated domain-containing protein | - |
| EL352_RS13010 () | 90877..91086 | - | 210 | WP_002325575.1 | heavy-metal-associated domain-containing protein | - |
| EL352_RS13015 () | 91103..93553 | - | 2451 | WP_002294783.1 | heavy metal translocating P-type ATPase | - |
| EL352_RS13020 () | 93537..93902 | - | 366 | WP_002307652.1 | BlaI/MecI/CopY family transcriptional regulator | - |
| EL352_RS13025 () | 93918..94532 | - | 615 | WP_002319974.1 | TIGR01906 family membrane protein | - |
| EL352_RS13030 () | 94688..95491 | + | 804 | WP_002294779.1 | prolipoprotein diacylglyceryl transferase | - |
| EL352_RS13035 () | 95475..95699 | + | 225 | WP_002307648.1 | DUF2933 domain-containing protein | - |
| EL352_RS13040 () | 95702..95881 | + | 180 | WP_002325573.1 | DUF2933 domain-containing protein | - |
| EL352_RS13045 () | 95995..97545 | - | 1551 | WP_002294773.1 | IS1182 family transposase ISSau3 | Transposase |
| EL352_RS13050 () | 98256..99539 | - | 1284 | WP_002325571.1 | hypothetical protein | - |
| EL352_RS13055 () | 99718..100125 | - | 408 | WP_002294770.1 | NusG domain II-containing protein | - |
| EL352_RS13060 () | 100397..101896 | + | 1500 | WP_002294768.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| EL352_RS13065 () | 101899..102587 | + | 689 | Protein_106 | Sortase A | VF |
| EL352_RS13075 () | 103125..103421 | - | 297 | WP_033602755.1 | hypothetical protein | - |
| EL352_RS13080 () | 103503..103769 | - | 267 | WP_126333306.1 | YfhO family protein | - |
| EL352_RS13090 () | 105568..106746 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EL352_RS13095 () | 107031..108935 | - | 1905 | WP_002293759.1 | heavy metal translocating P-type ATPase | - |
| EL352_RS13100 () | 109133..109366 | - | 234 | WP_002293760.1 | cation transporter | - |
| EL352_RS13105 () | 109513..110367 | - | 855 | WP_002293762.1 | prolipoprotein diacylglyceryl transferase | - |
| EL352_RS13110 () | 110352..110690 | - | 339 | WP_002293763.1 | hypothetical protein | - |
| EL352_RS13120 () | 110919..111623 | - | 705 | WP_002293764.1 | Crp/Fnr family transcriptional regulator | - |
| EL352_RS13125 () | 111768..112340 | - | 573 | WP_002292150.1 | DNA protection during starvation protein | VF |
| EL352_RS13130 () | 112811..113425 | + | 615 | WP_002293768.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EL352_RS13135 () | 113476..114579 | - | 1104 | WP_002293769.1 | Abi family protein | - |
| EL352_RS13145 () | 115069..115749 | - | 681 | WP_002325565.1 | IS6 family transposase IS1216E | Transposase |
| EL352_RS13150 () | 115766..116641 | + | 876 | WP_010726727.1 | IS21 family transposase IS1491 | Transposase |
| EL352_RS13155 () | 116641..117393 | + | 753 | WP_002325566.1 | IS21 family transposase ISBmu3 | Transposase |
| EL352_RS13160 () | 117576..118151 | - | 576 | WP_002293722.1 | hypothetical protein | - |
| EL352_RS13165 () | 118939..119511 | + | 573 | WP_002293724.1 | HAD-IIIA family hydrolase | - |
| EL352_RS13170 () | 119704..120267 | + | 564 | WP_000017403.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| EL352_RS13175 () | 120546..120833 | - | 288 | WP_000312841.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL352_RS13180 () | 120823..121152 | - | 330 | WP_000629052.1 | hypothetical protein | - |
| EL352_RS13185 () | 121457..121786 | + | 330 | WP_000754864.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EL352_RS13190 () | 122073..122558 | - | 486 | WP_000516404.1 | glycopeptide resistance protein VanZ-A | - |
| EL352_RS13195 () | 122711..123622 | - | 912 | WP_001812592.1 | D-Ala-D-Ala carboxypeptidase VanY-A | - |
| EL352_RS13200 () | 124050..124658 | - | 609 | WP_000402348.1 | D-alanyl-D-alanine dipeptidase | ARG |
| EL352_RS13205 () | 124664..125695 | - | 1032 | WP_001079845.1 | Vancomycin/teicoplanin A-type resistance protein VanA | ARG |
| EL352_RS13210 () | 125688..126656 | - | 969 | WP_001059542.1 | D-specific alpha-keto acid dehydrogenase | ARG |
| EL352_RS13215 () | 126871..128025 | - | 1155 | WP_002305818.1 | VanA-type vancomycin resistance histidine kinase VanS | - |
| EL352_RS13220 () | 128003..128698 | - | 696 | WP_001280781.1 | Transcriptional regulatory protein WalR | VF |
| EL352_RS13225 () | 128912..129487 | - | 576 | WP_001226076.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| EL352_RS13230 () | 129633..132557 | + | 2925 | WP_002293753.1 | Tn3 family transposase Tn4430 | Transposase |
| EL352_RS13235 () | 132642..133502 | - | 861 | WP_002293754.1 | IS3 family transposase ISSau2 | Transposase |
| EL352_RS13240 () | 133490..133837 | - | 348 | WP_002311518.1 | IS3 family transposase ISSau2 | Transposase |
| EL352_RS13245 () | 133865..134077 | - | 213 | Protein_139 | transposase | - |
| EL352_RS13250 () | 134078..134758 | - | 681 | WP_002325565.1 | IS6 family transposase IS1216E | Transposase |
| EL352_RS13255 () | 134834..135307 | - | 474 | Protein_141 | S8 family serine peptidase | - |
| EL352_RS13260 () | 135319..136047 | - | 729 | WP_002295679.1 | peptidase | - |
| EL352_RS13265 () | 136307..136855 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EL352_RS13270 () | 136856..137713 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EL352_RS13275 () | 137999..138184 | - | 186 | WP_100066491.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL352_RS13280 () | 138738..138824 | - | 87 | Protein_146 | single-stranded DNA-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|