NZ_LR134337394890..609922

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 215033 bp
Accession: NZ_LR134337        Location: 394890..609922         Organism: Enterococcus faecium strain NCTC7174       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL154_RS02055 () 392140..393513 - 1374 WP_002325300.1 PTS transporter subunit EIIC -
EL154_RS02060 () 393513..393908 - 396 WP_002286295.1 D-ribose pyranase -
EL154_RS02065 () 393936..394853 - 918 WP_002327464.1 ribokinase -
EL154_RS02070 () 394962..395975 - 1014 WP_126331763.1 substrate-binding domain-containing protein -
EL154_RS02075 () 396056..396655 - 600 WP_002327463.1 cysteine hydrolase -
EL154_RS02080 () 396840..397541 + 702 WP_002296067.1 putative ABC transporter ATP-binding protein VF
EL154_RS02085 () 397551..400271 + 2721 WP_002328767.1 ABC transporter permease -
EL154_RS02090 () 400668..402296 + 1629 WP_002327460.1 alpha,alpha-phosphotrehalase -
EL154_RS02100 () 402356..403537 - 1182 WP_002327459.1 AI-2E family transporter -
EL154_RS02105 () 403789..405315 + 1527 WP_002327458.1 hypothetical protein VF
EL154_RS02110 () 405384..406112 - 729 WP_002327457.1 LytTR family DNA-binding domain-containing protein -
EL154_RS02115 () 406125..407405 - 1281 WP_002327456.1 sensor histidine kinase -
EL154_RS02120 () 407546..408148 - 603 WP_002296063.1 accessory gene regulator B family protein -
EL154_RS02125 () 408392..408598 + 207 WP_002286271.1 hypothetical protein -
EL154_RS02135 () 408902..409621 + 720 WP_002321450.1 deoxynucleoside kinase -
EL154_RS02145 () 409702..410385 - 684 WP_002286265.1 DUF1275 domain-containing protein -
EL154_RS02150 () 410603..412789 + 2187 WP_002327455.1 ATP-dependent helicase -
EL154_RS02155 () 413136..413546 + 411 WP_002286258.1 Spx/MgsR family RNA polymerase-binding regulatory protein -
EL154_RS02160 () 413560..413916 + 357 WP_002286247.1 arsenate reductase -
EL154_RS02185 () 419669..420139 - 471 WP_002327454.1 glutathione peroxidase -
EL154_RS02190 () 420298..420756 - 459 WP_002289439.1 S-ribosylhomocysteine lyase VF
EL154_RS02195 () 420927..422072 - 1146 WP_002289438.1 cystathionine gamma-synthase -
EL154_RS02200 () 422085..423002 - 918 WP_002289436.1 cysteine synthase family protein -
EL154_RS02215 () 423430..423993 + 564 WP_002289434.1 elongation factor P -
EL154_RS02220 () 424479..425738 + 1260 WP_002305975.1 diaminopimelate decarboxylase -
EL154_RS02225 () 425725..426525 + 801 WP_002327453.1 diaminopimelate epimerase -
EL154_RS02230 () 426528..427409 + 882 WP_002327452.1 4-hydroxy-tetrahydrodipicolinate synthase -
EL154_RS02235 () 427406..428122 + 717 WP_002327451.1 4-hydroxy-tetrahydrodipicolinate reductase -
EL154_RS02240 () 428128..428823 + 696 WP_002301230.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase VF
EL154_RS02245 () 428839..429840 + 1002 WP_002327450.1 aspartate-semialdehyde dehydrogenase -
EL154_RS02250 () 429837..431198 + 1362 WP_002327449.1 aspartate kinase -
EL154_RS02255 () 431158..432309 + 1152 WP_002297890.1 amidohydrolase -
EL154_RS02260 () 432284..433453 + 1170 WP_002328565.1 pyridoxal phosphate-dependent aminotransferase -
EL154_RS02265 () 433628..435007 + 1380 WP_002286868.1 FAD-dependent oxidoreductase -
EL154_RS02270 () 435288..435949 + 662 Protein_418 IS3 family transposase ISEfa10 Transposase
EL154_RS02275 () 436167..436835 + 669 WP_002293693.1 DUF421 domain-containing protein -
EL154_RS02280 () 437031..437417 - 387 WP_002293692.1 hypothetical protein -
EL154_RS02285 () 437389..438771 - 1383 WP_002327444.1 Y-family DNA polymerase -
EL154_RS02290 () 438927..440114 - 1188 WP_002327443.1 galactokinase -
EL154_RS02295 () 440121..441152 - 1032 WP_002325138.1 galactose mutarotase -
EL154_RS02300 () 441168..442622 - 1455 WP_002293689.1 glycoside-pentoside-hexuronide (GPH):cation symporter -
EL154_RS02305 () 442797..443702 + 906 WP_002286852.1 AraC family transcriptional regulator -
EL154_RS02310 () 443793..444470 + 678 WP_002327442.1 NAD(P)H-dependent oxidoreductase -
EL154_RS12550 () 444467..444637 + 171 WP_002286849.1 hypothetical protein -
EL154_RS02315 () 444751..445647 + 897 WP_126331765.1 LysM peptidoglycan-binding domain-containing protein -
EL154_RS02320 () 445702..447072 - 1371 WP_002318348.1 amino acid permease -
EL154_RS02325 () 447310..448056 + 747 WP_002327440.1 Manganese import ATP-binding protein ScaC VF
EL154_RS02330 () 448053..448892 + 840 WP_002286845.1 Manganese transport system membrane protein MntB VF
EL154_RS02335 () 448893..449843 + 951 WP_002327439.1 Manganese ABC transporter substrate-binding lipoprotein VF
EL154_RS02340 () 449983..450735 + 753 WP_002327438.1 hypothetical protein -
EL154_RS02345 () 450754..451905 + 1152 WP_002293684.1 tRNA epoxyqueuosine(34) reductase QueG -
EL154_RS02350 () 452289..452897 + 609 WP_002286836.1 LysM domain-containing protein -
EL154_RS02355 () 453065..454702 + 1638 WP_002327437.1 phosphoenolpyruvate carboxykinase (ATP) -
EL154_RS02360 () 454774..455886 - 1113 WP_002327436.1 FAD-binding oxidoreductase -
EL154_RS02365 () 455961..457334 - 1374 WP_002293681.1 MFS transporter -
EL154_RS02370 () 457555..458172 + 618 WP_002325134.1 GyrI-like domain-containing protein -
EL154_RS02375 () 458270..458725 + 456 WP_002286829.1 arginine repressor -
EL154_RS02380 () 458743..460245 + 1503 WP_002327435.1 Phosphomannomutase/phosphoglucomutase VF
EL154_RS02385 () 460340..460546 + 207 WP_002293677.1 hypothetical protein -
EL154_RS02390 () 460632..461033 + 402 WP_002286825.1 organic hydroperoxide resistance protein -
EL154_RS02395 () 461191..462519 + 1329 WP_002327434.1 FAD-containing oxidoreductase -
EL154_RS02400 () 462541..463167 + 627 WP_002286816.1 cysteine hydrolase -
EL154_RS02405 () 463350..463931 + 582 WP_126331766.1 TetR/AcrR family transcriptional regulator -
EL154_RS02415 () 464296..464871 + 576 WP_002352505.1 SOS response-associated peptidase family protein -
EL154_RS02420 () 465077..465451 - 375 WP_158076077.1 hypothetical protein -
EL154_RS02430 () 465711..465941 + 231 WP_002323011.1 hypothetical protein Antitoxin Detail
EL154_RS02435 () 465941..466282 + 342 WP_002286801.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
EL154_RS02440 () 467132..467317 + 186 WP_002304207.1 hypothetical protein -
EL154_RS02445 () 467587..468749 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
EL154_RS12555 () 468997..469122 + 126 WP_025478972.1 LPXTG cell wall anchor domain-containing protein -
EL154_RS02455 () 469196..470092 + 897 WP_002352497.1 hypothetical protein VF
EL154_RS02460 () 470273..470947 + 675 WP_002291233.1 Response regulator protein GraR VF
EL154_RS02465 () 470965..471990 + 1026 WP_002327427.1 sensor histidine kinase -
EL154_RS02470 () 472079..472945 + 867 WP_002286769.1 glucose transporter GlcU -
EL154_RS02475 () 472982..474358 + 1377 WP_002327426.1 amino acid permease -
EL154_RS02480 () 474459..475655 - 1197 WP_002286766.1 toxic anion resistance protein -
EL154_RS02485 () 475779..476441 - 663 WP_002327425.1 5-bromo-4-chloroindolyl phosphate hydrolysis family protein -
EL154_RS02490 () 476668..477231 + 564 WP_002325125.1 NUDIX hydrolase -
EL154_RS02495 () 477244..477528 + 285 WP_002286760.1 cell wall synthase accessory phosphoprotein MacP -
EL154_RS02500 () 477547..478239 + 693 WP_002291218.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
EL154_RS02505 () 478251..478796 + 546 WP_002291217.1 Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB VF
EL154_RS02510 () 479068..482346 + 3279 WP_002327423.1 right-handed parallel beta-helix repeat-containing protein -
EL154_RS02515 () 482886..484793 - 1908 WP_126331767.1 M13 family peptidase -
EL154_RS02520 () 484923..485798 + 876 WP_002327421.1 dihydrolipoamide dehydrogenase -
EL154_RS02525 () 485878..486852 + 975 WP_002286741.1 ribose-phosphate diphosphokinase -
EL154_RS02530 () 487032..488177 + 1146 WP_002352493.1 cysteine desulfurase -
EL154_RS02535 () 488314..488658 + 345 WP_002286736.1 DUF1831 domain-containing protein -
EL154_RS02540 () 488929..490202 + 1274 Protein_471 multidrug efflux MFS transporter EfmA -
EL154_RS02545 () 490352..490951 - 600 WP_002291205.1 metallophosphoesterase -
EL154_RS02550 () 491355..492476 + 1122 WP_002327417.1 tRNA 2-thiouridine(34) synthase MnmA -
EL154_RS02555 () 492724..494145 + 1422 WP_002327416.1 arginine-ornithine antiporter -
EL154_RS02560 () 494159..495277 + 1119 WP_002325117.1 aminotransferase -
EL154_RS02565 () 495337..496629 - 1293 WP_002327415.1 multidrug efflux MFS transporter -
EL154_RS02570 () 496761..497339 + 579 WP_172594867.1 WHG domain-containing protein -
EL154_RS02575 () 497468..497845 + 378 WP_002291196.1 DUF1033 family protein -
EL154_RS02580 () 497778..499850 + 2073 WP_033581948.1 DNA topoisomerase III -
EL154_RS02585 () 500061..501008 - 948 WP_002318912.1 Prophage bactoprenol glucosyl transferase VF
EL154_RS02590 () 501253..501717 + 465 WP_002298278.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
EL154_RS02595 () 501779..502822 - 1044 WP_002291191.1 putative sulfate exporter family transporter -
EL154_RS02610 () 503322..504287 - 966 WP_002291188.1 TDT family transporter -
EL154_RS02615 () 504521..505366 + 846 WP_002291186.1 HTH-type transcriptional regulator CysL VF
EL154_RS02625 () 505557..506744 + 1188 WP_002318915.1 FtsW/RodA/SpoVE family cell cycle protein -
EL154_RS02630 () 506750..507106 + 357 WP_002295166.1 arsenate reductase family protein -
EL154_RS02635 () 507108..507446 + 339 WP_002291179.1 glycine cleavage system protein H -
EL154_RS02640 () 507841..508875 + 1035 WP_002304234.1 Methionine import ATP-binding protein MetN 2 VF
EL154_RS02645 () 508868..509554 + 687 WP_002287674.1 ABC transporter permease -
EL154_RS02650 () 509578..510426 + 849 WP_002318916.1 Methionine-binding lipoprotein MetQ VF
EL154_RS02655 () 510623..511396 + 774 WP_002327676.1 Fe-S cluster assembly ATPase SufC -
EL154_RS02660 () 511409..512695 + 1287 WP_002327410.1 Fe-S cluster assembly protein SufD -
EL154_RS02665 () 512692..513927 + 1236 WP_002318918.1 cysteine desulfurase -
EL154_RS02670 () 513914..514384 + 471 WP_002287684.1 SUF system NifU family Fe-S cluster assembly protein -
EL154_RS02675 () 514389..515780 + 1392 WP_002287686.1 Fe-S cluster assembly protein SufB -
EL154_RS02680 () 515875..517017 - 1143 WP_002287705.1 Tyrosine recombinase XerC ; Integrase Integrase
EL154_RS02685 () 517056..517790 - 735 WP_002287709.1 helix-turn-helix domain-containing protein -
EL154_RS02695 () 518022..518297 + 276 WP_002287723.1 helix-turn-helix domain-containing protein -
EL154_RS02700 () 518395..520392 + 1998 Protein_499 hypothetical protein -
EL154_RS02705 () 520468..520803 - 336 WP_002301912.1 helix-turn-helix transcriptional regulator -
EL154_RS02710 () 520930..521145 + 216 WP_002298398.1 helix-turn-helix transcriptional regulator -
EL154_RS02715 () 521182..521544 + 363 WP_002298396.1 zinc ribbon domain-containing protein -
EL154_RS02720 () 521590..521916 + 327 WP_002298394.1 hypothetical protein -
EL154_RS02730 () 522759..524582 + 1824 WP_002298390.1 beta-glucoside-specific PTS transporter subunit IIABC -
EL154_RS02735 () 524596..526005 + 1410 WP_002298389.1 glycoside hydrolase family 1 protein -
EL154_RS02740 () 526023..526859 + 837 WP_002298387.1 PRD domain-containing protein -
EL154_RS02745 () 526924..527706 + 783 WP_002317770.1 hypothetical protein -
EL154_RS02750 () 528215..529366 + 1152 Protein_508 type I restriction-modification system subunit M -
EL154_RS02755 () 529445..530571 + 1127 WP_094850654.1 IS3 family transposase ISBce13 Transposase
EL154_RS02760 () 530616..531803 + 1188 Protein_510 ISL3 family transposase IS1251 Transposase
EL154_RS02765 () 531923..532123 + 201 WP_002297848.1 HAMP domain-containing histidine kinase -
EL154_RS02770 () 532199..532396 + 198 WP_002297850.1 hypothetical protein -
EL154_RS02780 () 532693..534240 - 1548 WP_002297851.1 bifunctional metallophosphatase/5'-nucleotidase -
EL154_RS02785 () 534324..535127 - 804 WP_002297853.1 metallophosphoesterase -
EL154_RS02790 () 535130..535912 - 783 WP_002297855.1 phosphonate ABC transporter, permease protein PhnE -
EL154_RS02795 () 535909..536688 - 780 WP_002297856.1 phosphonate ABC transporter, permease protein PhnE -
EL154_RS02800 () 536660..537451 - 792 WP_002297857.1 Glutamine transport ATP-binding protein GlnQ VF
EL154_RS02805 () 537512..538441 - 930 WP_002297858.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
EL154_RS02810 () 538636..539319 + 684 WP_002297859.1 cyclic nucleotide-binding domain-containing protein -
EL154_RS02815 () 539480..540523 + 1044 WP_002340328.1 BMP family ABC transporter substrate-binding protein -
EL154_RS02820 () 540587..542050 + 1464 Protein_521 IS1182 family transposase ISEfa7 Transposase
EL154_RS02825 () 542320..543462 - 1143 WP_002344956.1 Tyrosine recombinase XerC ; Integrase Integrase
EL154_RS02830 () 543513..543866 - 354 Protein_523 transcriptional regulator -
EL154_RS02850 () 545803..546117 + 315 WP_126331770.1 hypothetical protein -
EL154_RS02855 () 546170..546928 - 759 WP_033603054.1 hypothetical protein -
EL154_RS02860 () 547049..547294 + 246 WP_002313380.1 helix-turn-helix domain-containing protein -
EL154_RS02865 () 547370..547648 + 279 WP_002314576.1 hypothetical protein -
EL154_RS02870 () 548292..548717 + 426 WP_002316489.1 hypothetical protein -
EL154_RS02875 () 549327..550823 - 1497 WP_010718305.1 helix-turn-helix domain-containing protein -
EL154_RS02880 () 551178..554630 + 3453 WP_071243093.1 hypothetical protein VF
EL154_RS02885 () 554633..556048 + 1416 WP_071243092.1 hypothetical protein VF
EL154_RS02890 () 556045..557922 + 1878 WP_126331771.1 hypothetical protein VF
EL154_RS02895 () 558014..558844 + 831 WP_038809780.1 hypothetical protein VF
EL154_RS02910 () 560746..561516 - 771 Protein_536 HAD hydrolase-like protein -
EL154_RS02915 () 561521..562288 - 768 WP_002345826.1 DeoR/GlpR family DNA-binding transcription regulator -
EL154_RS02920 () 562776..563201 + 426 WP_002290555.1 galactose-6-phosphate isomerase subunit LacA -
EL154_RS02925 () 563218..563733 + 516 WP_002345825.1 galactose-6-phosphate isomerase subunit LacB -
EL154_RS02930 () 563744..564676 + 933 WP_002290553.1 tagatose-6-phosphate kinase -
EL154_RS02935 () 564679..565659 + 981 WP_002290551.1 tagatose-bisphosphate aldolase -
EL154_RS02940 () 565687..566004 + 318 WP_002290550.1 PTS lactose/cellobiose transporter subunit IIA -
EL154_RS02945 () 566004..567710 + 1707 WP_002343085.1 lactose-specific PTS transporter subunit EIIC -
EL154_RS02950 () 567852..569258 + 1407 WP_010718300.1 6-phospho-beta-galactosidase -
EL154_RS12560 () 569381..569554 + 174 WP_164884865.1 DUF3884 family protein -
EL154_RS02960 () 569575..570474 + 900 WP_010718299.1 aldose 1-epimerase family protein -
EL154_RS02965 () 570806..571096 - 291 WP_010718298.1 hypothetical protein -
EL154_RS02970 () 571177..571680 - 504 Protein_548 peptidase -
EL154_RS02975 () 571643..571879 + 237 WP_071243184.1 helix-turn-helix domain-containing protein -
EL154_RS02980 () 572116..574230 + 2115 WP_071243185.1 putative ATP-dependent Clp protease ATP-binding subunit VF
EL154_RS02985 () 574411..574725 - 315 Protein_551 transposase -
EL154_RS02990 () 574798..575034 + 237 WP_002341366.1 hypothetical protein -
EL154_RS02995 () 575253..575444 + 192 WP_002314345.1 hypothetical protein -
EL154_RS03000 () 575962..577311 + 1350 WP_063285975.1 primase C-terminal domain-containing protein -
EL154_RS03005 () 577355..577549 + 195 WP_002311030.1 hypothetical protein -
EL154_RS12565 () 577563..577703 + 141 WP_002316998.1 hypothetical protein -
EL154_RS03010 () 577681..579522 + 1842 WP_073981265.1 type IA DNA topoisomerase -
EL154_RS03015 () 580079..580267 + 189 WP_038809792.1 hypothetical protein -
EL154_RS03025 () 580992..581414 + 423 WP_002307506.1 cupin domain-containing protein -
EL154_RS03030 () 581498..582151 + 654 WP_025370695.1 putative iron export ATP-binding protein FetA VF
EL154_RS03035 () 582148..582912 + 765 WP_002311027.1 iron export ABC transporter permease subunit FetB -
EL154_RS03045 () 583422..584584 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
EL154_RS03055 () 586595..587245 - 651 WP_047649791.1 helix-turn-helix domain-containing protein -
EL154_RS03060 () 587424..589406 + 1983 WP_047649792.1 DUF1430 domain-containing protein -
EL154_RS03065 () 589410..590048 + 639 WP_002325867.1 putative ABC transporter ATP-binding protein YknY VF
EL154_RS03070 () 590424..591335 + 912 WP_002316482.1 Foldase protein PrsA VF
EL154_RS03075 () 591552..591989 + 438 WP_002328523.1 hypothetical protein -
EL154_RS03080 () 592084..592968 + 885 WP_126331879.1 diacylglycerol kinase family lipid kinase -
EL154_RS03090 () 593189..596359 + 3171 WP_126331772.1 hypothetical protein -
EL154_RS03095 () 596379..597407 + 1029 WP_047649794.1 DUF916 and DUF3324 domain-containing protein -
EL154_RS03100 () 597404..598162 + 759 WP_002321097.1 WxL domain-containing protein -
EL154_RS03105 () 598419..599378 - 960 WP_002293280.1 IS30 family transposase IS6770 Transposase
EL154_RS03110 () 599475..600056 - 582 Protein_573 response regulator -
EL154_RS03115 () 600117..601370 + 1254 WP_126331773.1 GHKL domain-containing protein -
EL154_RS03120 () 601671..601919 + 249 Protein_575 winged helix-turn-helix transcriptional regulator -
EL154_RS03125 () 602041..602367 + 327 WP_002291148.1 nucleotide pyrophosphohydrolase -
EL154_RS03130 () 602435..603148 + 714 WP_002318718.1 class A sortase -
EL154_RS03135 () 603458..604310 + 853 Protein_578 PRD domain-containing protein -
EL154_RS03140 () 604431..606296 + 1866 WP_126331774.1 beta-glucoside-specific PTS transporter subunit IIABC -
EL154_RS03145 () 606310..607752 + 1443 WP_126331775.1 glycoside hydrolase family 1 protein -
EL154_RS03150 () 607860..608561 + 702 WP_002293839.1 GntR family transcriptional regulator -
EL154_RS03160 () 608720..609199 + 480 Protein_582 PTS fructose transporter subunit IIC -
EL154_RS03175 () 610047..610622 + 576 WP_002340344.1 TIGR00730 family Rossman fold protein -
EL154_RS03180 () 610622..611062 + 441 WP_002293607.1 nucleoside deoxyribosyltransferase -
EL154_RS03185 () 611078..611779 + 702 WP_002340345.1 deoxynucleoside kinase -
EL154_RS03195 () 612267..612692 - 426 WP_002299985.1 hypothetical protein -
EL154_RS03200 () 613066..614037 + 972 WP_002299983.1 LacI family transcriptional regulator -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance