MGE detailed information
MGE type: Conjugative plasmid MGE length: 124410 bp
Accession: NZ_CP121200 Location: 1..124410 Organism: Escherichia coli strain E50 Replicon: plasmid pE50-1
Accession: NZ_CP121200 Location: 1..124410 Organism: Escherichia coli strain E50 Replicon: plasmid pE50-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P6H83_RS23745 (539) | 539..1627 | - | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| P6H83_RS23750 (2172) | 2172..2522 | + | 351 | WP_000493379.1 | hypothetical protein | - |
| P6H83_RS23755 (2566) | 2566..3255 | + | 690 | WP_000796228.1 | hypothetical protein | - |
| P6H83_RS23760 (3252) | 3252..4043 | + | 792 | WP_000016493.1 | site-specific integrase | - |
| P6H83_RS23770 (4859) | 4859..5127 | + | 269 | Protein_6 | IS3 family transposase ISLad1 | Transposase |
| P6H83_RS23780 (6627) | 6627..6806 | + | 180 | Protein_8 | integrase core domain-containing protein | - |
| P6H83_RS23785 (8103) | 8103..9056 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| P6H83_RS23790 (9489) | 9489..10598 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| P6H83_RS23795 (10667) | 10667..11569 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| P6H83_RS23800 (11943) | 11943..12131 | + | 189 | WP_014640565.1 | hypothetical protein | - |
| P6H83_RS23805 (12252) | 12252..12992 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| P6H83_RS23810 (13277) | 13277..14254 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| P6H83_RS23820 (16261) | 16261..16455 | + | 195 | Protein_16 | IS21 family transposase IS21 | Transposase |
| P6H83_RS23825 (16512) | 16512..17209 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| P6H83_RS23830 (17509) | 17509..18675 | + | 1167 | WP_001238646.1 | hypothetical protein | VF |
| P6H83_RS23835 (18675) | 18675..19646 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| P6H83_RS23840 (20283) | 20283..20452 | + | 170 | Protein_20 | hypothetical protein | - |
| P6H83_RS23845 (20449) | 20449..20796 | + | 348 | WP_001350917.1 | hypothetical protein | - |
| P6H83_RS23850 (20865) | 20865..21200 | + | 336 | WP_000343070.1 | hypothetical protein | - |
| P6H83_RS23855 (21251) | 21251..21948 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| P6H83_RS23860 (22001) | 22001..22972 | - | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| P6H83_RS23865 (23374) | 23374..23799 | + | 426 | WP_001198922.1 | antirestriction protein | - |
| P6H83_RS23870 (23799) | 23799..24260 | + | 462 | WP_042007484.1 | DUF1380 family protein | - |
| P6H83_RS23875 (24260) | 24260..24442 | + | 183 | WP_001027505.1 | hypothetical protein | - |
| P6H83_RS23880 (24666) | 24666..24919 | - | 254 | Protein_28 | hypothetical protein | - |
| P6H83_RS23885 (25436) | 25436..25666 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| P6H83_RS23890 (25718) | 25718..27079 | + | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| P6H83_RS23895 (27125) | 27125..27688 | + | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| P6H83_RS23900 (27688) | 27688..27930 | + | 243 | WP_001610271.1 | hypothetical protein | - |
| P6H83_RS23905 (27840) | 27840..28100 | + | 261 | WP_072132736.1 | hypothetical protein | - |
| P6H83_RS23910 (28573) | 28573..29100 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| P6H83_RS23915 (29156) | 29156..29389 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| P6H83_RS23920 (29448) | 29448..31406 | + | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| P6H83_RS23925 (31461) | 31461..31895 | + | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| P6H83_RS23930 (31892) | 31892..32654 | + | 763 | Protein_38 | plasmid SOS inhibition protein A | - |
| P6H83_RS23935 (32623) | 32623..32811 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (32623) | 32623..32820 | + | 198 | NuclAT_0 | - | - |
| - (32623) | 32623..32820 | + | 198 | NuclAT_0 | - | - |
| - (32623) | 32623..32820 | + | 198 | NuclAT_0 | - | - |
| - (32623) | 32623..32820 | + | 198 | NuclAT_0 | - | - |
| P6H83_RS23940 (32868) | 32868..34237 | + | 1370 | WP_087522250.1 | IS3-like element IS150 family transposase | - |
| - (34262) | 34262..34293 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (34262) | 34262..34293 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (34262) | 34262..34293 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| - (34262) | 34262..34293 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| P6H83_RS23945 (34279) | 34279..34428 | + | 150 | Protein_41 | plasmid maintenance protein Mok | - |
| P6H83_RS23950 (34370) | 34370..34495 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| P6H83_RS23955 (34715) | 34715..34945 | + | 231 | WP_001426396.1 | hypothetical protein | - |
| P6H83_RS23960 (34943) | 34943..35116 | - | 174 | Protein_44 | hypothetical protein | - |
| P6H83_RS23965 (35186) | 35186..35392 | + | 207 | WP_000547939.1 | hypothetical protein | - |
| P6H83_RS23970 (35417) | 35417..35704 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| P6H83_RS23975 (35825) | 35825..36646 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| P6H83_RS23980 (36943) | 36943..37590 | - | 648 | WP_000614936.1 | hypothetical protein | VF |
| P6H83_RS23985 (37867) | 37867..38250 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| P6H83_RS23990 (38441) | 38441..39127 | + | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| P6H83_RS23995 (39221) | 39221..39448 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| P6H83_RS24000 (39482) | 39482..39841 | + | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| P6H83_RS24005 (39856) | 39856..40167 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| P6H83_RS24010 (40189) | 40189..40755 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| P6H83_RS24015 (40742) | 40742..41470 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| P6H83_RS24020 (41470) | 41470..42897 | + | 1428 | WP_000146685.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| P6H83_RS24025 (42887) | 42887..43459 | + | 573 | WP_000002780.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| P6H83_RS24030 (43456) | 43456..43773 | + | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| P6H83_RS24035 (43770) | 43770..44021 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| P6H83_RS24040 (44018) | 44018..44533 | + | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| P6H83_RS24045 (44668) | 44668..44889 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| P6H83_RS24050 (45049) | 45049..47676 | + | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| P6H83_RS24055 (47673) | 47673..48059 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| P6H83_RS24060 (48056) | 48056..48688 | + | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| P6H83_RS24065 (48685) | 48685..49677 | + | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| P6H83_RS24070 (49703) | 49703..50164 | + | 462 | WP_000277845.1 | hypothetical protein | - |
| P6H83_RS24075 (50194) | 50194..50646 | + | 453 | WP_000069427.1 | hypothetical protein | - |
| P6H83_RS24080 (50674) | 50674..51312 | + | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| P6H83_RS24085 (51309) | 51309..52169 | + | 861 | Protein_69 | conjugal transfer protein TraN | - |
| P6H83_RS24090 (52229) | 52229..52933 | + | 705 | WP_208789585.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24095 (52985) | 52985..53494 | + | 510 | Protein_71 | IS6 family transposase IS6100 | Transposase |
| P6H83_RS24100 (53987) | 53987..54571 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| P6H83_RS24105 (54571) | 54571..55809 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| P6H83_RS24110 (55806) | 55806..56711 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| P6H83_RS24115 (56833) | 56833..57537 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24120 (57588) | 57588..58148 | + | 561 | WP_021532377.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| P6H83_RS24125 (58151) | 58151..61117 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| P6H83_RS24130 (61196) | 61196..62200 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| P6H83_RS24135 (62419) | 62419..63057 | - | 639 | WP_061093065.1 | hypothetical protein | - |
| P6H83_RS24140 (63057) | 63057..63311 | - | 255 | WP_000343103.1 | hypothetical protein | - |
| P6H83_RS24145 (63663) | 63663..64664 | + | 1002 | WP_000774874.1 | DUF4238 domain-containing protein | - |
| P6H83_RS24150 (64840) | 64840..65184 | - | 345 | WP_000793307.1 | hypothetical protein | - |
| P6H83_RS24155 (65770) | 65770..66474 | + | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24160 (66922) | 66922..67935 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| P6H83_RS24165 (68091) | 68091..68564 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| P6H83_RS24170 (68634) | 68634..69338 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24175 (69392) | 69392..69706 | + | 315 | Protein_87 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| P6H83_RS24180 (69709) | 69709..72675 | + | 2967 | WP_001138070.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| P6H83_RS24185 (72754) | 72754..73530 | + | 777 | Protein_89 | IS110 family transposase IS5075 | Transposase |
| P6H83_RS24190 (73587) | 73587..73802 | - | 216 | Protein_90 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24195 (73865) | 73865..74569 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24200 (74623) | 74623..75321 | + | 699 | Protein_92 | Multifunctional conjugation protein TraI | Relaxase |
| P6H83_RS24205 (75341) | 75341..76087 | + | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| P6H83_RS24210 (76142) | 76142..76702 | + | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| P6H83_RS24215 (76840) | 76840..77052 | + | 213 | WP_012311405.1 | hypothetical protein | - |
| P6H83_RS24220 (77295) | 77295..77756 | + | 462 | WP_001233871.1 | thermonuclease family protein | - |
| P6H83_RS24225 (77802) | 77802..78011 | + | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| P6H83_RS24230 (78049) | 78049..78622 | + | 574 | Protein_98 | DUF2726 domain-containing protein | - |
| P6H83_RS24235 (78861) | 78861..79121 | + | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| P6H83_RS24240 (79147) | 79147..79383 | - | 237 | WP_223368648.1 | replication protein RepA | - |
| P6H83_RS24245 (79374) | 79374..79421 | + | 48 | WP_077822033.1 | hypothetical protein | - |
| P6H83_RS24250 (79414) | 79414..80271 | + | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| P6H83_RS24255 (80973) | 80973..81113 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| P6H83_RS24260 (81211) | 81211..81864 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| P6H83_RS24265 (81957) | 81957..82214 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| P6H83_RS24270 (82147) | 82147..82548 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| P6H83_RS24275 (82797) | 82797..83212 | + | 416 | Protein_107 | IS1-like element IS1B family transposase | - |
| P6H83_RS24280 (83248) | 83248..83793 | - | 546 | Protein_108 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P6H83_RS24285 (83859) | 83859..84563 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24290 (84628) | 84628..84807 | + | 180 | Protein_110 | IS1380 family transposase | - |
| P6H83_RS24295 (85057) | 85057..85932 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| P6H83_RS24300 (85967) | 85967..86935 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| P6H83_RS24305 (86992) | 86992..88089 | + | 1098 | Protein_113 | TonB-dependent receptor | - |
| P6H83_RS24310 (88157) | 88157..88546 | - | 390 | Protein_114 | Tn3 family transposase TnpA_Tn3 | Transposase |
| P6H83_RS24315 (88710) | 88710..89267 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| P6H83_RS24320 (89450) | 89450..89863 | + | 414 | Protein_116 | serine hydrolase | - |
| P6H83_RS24325 (89926) | 89926..90630 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24330 (90829) | 90829..91179 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| P6H83_RS24335 (91382) | 91382..92395 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| P6H83_RS24340 (92562) | 92562..93404 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| P6H83_RS24345 (93551) | 93551..94108 | + | 558 | WP_134894556.1 | HAD family hydrolase | - |
| P6H83_RS24350 (94166) | 94166..95004 | + | 839 | Protein_122 | Streptomycin 3''-adenylyltransferase | ARG |
| P6H83_RS24355 (95219) | 95219..96478 | + | 1260 | WP_000095725.1 | chloramphenicol efflux MFS transporter CmlA1 | ARG |
| P6H83_RS24360 (96571) | 96571..97409 | + | 839 | Protein_124 | Streptomycin 3''-adenylyltransferase | ARG |
| P6H83_RS24365 (97532) | 97532..97864 | + | 333 | WP_000800531.1 | quaternary ammonium compound efflux SMR transporter QacL | - |
| P6H83_RS24370 (98111) | 98111..98743 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| P6H83_RS24375 (98766) | 98766..99041 | + | 276 | WP_109023896.1 | hypothetical protein | - |
| P6H83_RS24380 (99044) | 99044..99835 | - | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| P6H83_RS24385 (100304) | 100304..100549 | - | 246 | WP_001354008.1 | GrpB family protein | - |
| P6H83_RS24390 (100587) | 100587..101450 | - | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| P6H83_RS24395 (101596) | 101596..101664 | - | 69 | Protein_131 | macrolide transporter | - |
| P6H83_RS24400 (101711) | 101711..102415 | - | 705 | WP_001067834.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24405 (102566) | 102566..103381 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| P6H83_RS24410 (103571) | 103571..103678 | - | 108 | Protein_134 | IS6 family transposase | - |
| P6H83_RS24415 (103735) | 103735..104439 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24420 (104490) | 104490..106070 | - | 1581 | Protein_136 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P6H83_RS24425 (106074) | 106074..106466 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| P6H83_RS24430 (106604) | 106604..107488 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| P6H83_RS24435 (107520) | 107520..108719 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| P6H83_RS24440 (108825) | 108825..109475 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| P6H83_RS24445 (109507) | 109507..109749 | - | 243 | WP_000844627.1 | transposase | - |
| P6H83_RS24450 (109807) | 109807..111321 | - | 1515 | Protein_142 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| P6H83_RS24455 (111387) | 111387..112091 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| P6H83_RS24460 (112144) | 112144..112464 | - | 321 | Protein_144 | NAD(P)H-dependent oxidoreductase | - |
| P6H83_RS24465 (112625) | 112625..112948 | - | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| P6H83_RS24470 (113053) | 113053..114132 | + | 1080 | WP_001089727.1 | permease | - |
| P6H83_RS24475 (114425) | 114425..115042 | - | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| P6H83_RS24480 (115234) | 115234..116790 | - | 1557 | WP_000818556.1 | AAA family ATPase | - |
| P6H83_RS24485 (117053) | 117053..117643 | - | 591 | WP_000194575.1 | hypothetical protein | - |
| P6H83_RS24490 (117643) | 117643..117900 | - | 258 | WP_000343085.1 | hypothetical protein | - |
| P6H83_RS24495 (118254) | 118254..120392 | + | 2139 | WP_000350638.1 | AAA family ATPase | - |
| P6H83_RS24500 (120554) | 120554..120970 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | - |
| P6H83_RS24505 (120967) | 120967..121197 | - | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| P6H83_RS24510 (121493) | 121493..121783 | + | 291 | WP_000111771.1 | hypothetical protein | - |
| P6H83_RS24515 (121773) | 121773..122672 | + | 900 | WP_000963206.1 | nucleotide-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|