MGE detailed information
MGE type: Conjugative plasmid MGE length: 124316 bp
Accession: NZ_CP118904 Location: 1..124316 Organism: Klebsiella pneumoniae strain CRKP Replicon: plasmid pCRKP-3
Accession: NZ_CP118904 Location: 1..124316 Organism: Klebsiella pneumoniae strain CRKP Replicon: plasmid pCRKP-3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PXG74_RS28285 (PXG74_28285) | 1..594 | + | 594 | WP_013609537.1 | fertility inhibition protein FinO | - |
| PXG74_RS28290 (PXG74_28290) | 755..1357 | + | 603 | WP_013023836.1 | PIN domain-containing protein | - |
| PXG74_RS28295 (PXG74_28295) | 1407..2051 | + | 645 | WP_014343481.1 | hypothetical protein | - |
| PXG74_RS28300 (PXG74_28300) | 2107..2757 | + | 651 | WP_014343480.1 | DUF2726 domain-containing protein | - |
| PXG74_RS28305 (PXG74_28305) | 2754..3062 | + | 309 | WP_004152383.1 | hypothetical protein | - |
| PXG74_RS28310 (PXG74_28310) | 3295..4155 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PXG74_RS28315 (PXG74_28315) | 4338..4895 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PXG74_RS28320 (PXG74_28320) | 5059..5277 | + | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PXG74_RS28325 (PXG74_28325) | 5459..6721 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| PXG74_RS28330 (PXG74_28330) | 6977..7852 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| PXG74_RS28335 (PXG74_28335) | 7899..8243 | - | 345 | Protein_10 | WbuC family cupin fold metalloprotein | - |
| PXG74_RS28340 (PXG74_28340) | 8257..11040 | + | 2784 | Protein_11 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PXG74_RS28345 (PXG74_28345) | 11193..12944 | - | 1752 | Protein_12 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PXG74_RS28350 (PXG74_28350) | 12948..13340 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| PXG74_RS28355 (PXG74_28355) | 13478..14362 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| PXG74_RS28360 (PXG74_28360) | 14394..15593 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| PXG74_RS28365 (PXG74_28365) | 15699..16349 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| PXG74_RS28370 (PXG74_28370) | 16381..16623 | - | 243 | WP_000844627.1 | transposase | - |
| PXG74_RS28375 (PXG74_28375) | 16681..16935 | - | 255 | Protein_18 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| PXG74_RS28380 (PXG74_28380) | 17000..17704 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PXG74_RS28385 (PXG74_28385) | 17826..18731 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| PXG74_RS28390 (PXG74_28390) | 18728..19966 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| PXG74_RS28395 (PXG74_28395) | 19966..20550 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| PXG74_RS28400 (PXG74_28400) | 21043..21807 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| PXG74_RS28405 (PXG74_28405) | 21925..21990 | - | 66 | Protein_24 | EAL domain-containing protein | - |
| PXG74_RS28410 (PXG74_28410) | 22034..22339 | - | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| PXG74_RS28415 (PXG74_28415) | 22350..23555 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| PXG74_RS28420 (PXG74_28420) | 23783..24787 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| PXG74_RS28425 (PXG74_28425) | 24969..25241 | - | 273 | WP_004883563.1 | hypothetical protein | - |
| PXG74_RS28430 (PXG74_28430) | 25369..26208 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| PXG74_RS28435 (PXG74_28435) | 26202..26549 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| PXG74_RS28440 (PXG74_28440) | 26575..26685 | + | 111 | Protein_31 | helix-turn-helix domain-containing protein | - |
| PXG74_RS28445 (PXG74_28445) | 26780..27424 | + | 645 | WP_001749994.1 | Pentapeptide repeat protein | ARG |
| PXG74_RS28450 (PXG74_28450) | 27516..28424 | - | 909 | WP_001749993.1 | putative oxidoreductase YghA | VF |
| PXG74_RS28455 (PXG74_28455) | 28889..30430 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| PXG74_RS28460 (PXG74_28460) | 30835..31674 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| PXG74_RS28465 (PXG74_28465) | 31668..32015 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| PXG74_RS28470 (PXG74_28470) | 32132..32977 | - | 846 | WP_001749984.1 | Streptomycin 3''-adenylyltransferase | ARG |
| PXG74_RS28475 (PXG74_28475) | 33158..33631 | - | 474 | WP_001749985.1 | IS1595 family transposase ISSsu9 | ARG |
| PXG74_RS28480 (PXG74_28480) | 33764..34216 | - | 453 | WP_001749986.1 | hypothetical protein | ARG |
| PXG74_RS28485 (PXG74_28485) | 34313..34867 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| PXG74_RS28490 (PXG74_28490) | 35159..36172 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| PXG74_RS28495 (PXG74_28495) | 36647..37351 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PXG74_RS28500 (PXG74_28500) | 37675..39252 | + | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| PXG74_RS28505 (PXG74_28505) | 39426..39935 | + | 510 | WP_052145515.1 | Phospholipase D | VF |
| PXG74_RS28510 (PXG74_28510) | 40053..40322 | + | 270 | WP_013609506.1 | replication regulatory protein RepA | - |
| PXG74_RS28515 (PXG74_28515) | 40554..40631 | + | 78 | WP_004171457.1 | RepA leader peptide Tap | - |
| PXG74_RS28520 (PXG74_28520) | 40624..41481 | + | 858 | WP_013023768.1 | incFII family plasmid replication initiator RepA | - |
| PXG74_RS28525 (PXG74_28525) | 42673..43854 | - | 1182 | WP_013023770.1 | DUF4268 domain-containing protein | - |
| PXG74_RS28530 (PXG74_28530) | 44137..44286 | - | 150 | Protein_49 | IS110 family transposase | - |
| PXG74_RS28535 (PXG74_28535) | 44372..45397 | + | 1026 | WP_001101446.1 | IS110 family transposase ISAve1 | Transposase |
| PXG74_RS28540 (PXG74_28540) | 45716..45883 | - | 168 | Protein_51 | IS5/IS1182 family transposase | - |
| PXG74_RS28545 (PXG74_28545) | 46019..46288 | + | 270 | Protein_52 | SOS response-associated peptidase family protein | - |
| PXG74_RS28550 (PXG74_28550) | 46467..46790 | + | 324 | WP_017899891.1 | hypothetical protein | - |
| PXG74_RS28555 (PXG74_28555) | 47031..47807 | + | 777 | WP_013609504.1 | DUF2971 domain-containing protein | - |
| PXG74_RS28560 (PXG74_28560) | 47943..48197 | - | 255 | WP_009653916.1 | hypothetical protein | - |
| PXG74_RS28565 (PXG74_28565) | 48273..48530 | - | 258 | WP_017899889.1 | hypothetical protein | - |
| PXG74_RS28570 (PXG74_28570) | 48579..48782 | - | 204 | WP_004098931.1 | HHA domain-containing protein | - |
| PXG74_RS28575 (PXG74_28575) | 48816..49184 | - | 369 | WP_015344965.1 | hypothetical protein | - |
| PXG74_RS28580 (PXG74_28580) | 49228..49722 | - | 495 | WP_013023776.1 | hypothetical protein | - |
| PXG74_RS28585 (PXG74_28585) | 49753..50319 | - | 567 | WP_013023777.1 | hypothetical protein | - |
| PXG74_RS28590 (PXG74_28590) | 50316..50579 | - | 264 | WP_013023778.1 | hypothetical protein | - |
| PXG74_RS28595 (PXG74_28595) | 50854..51354 | + | 501 | WP_013023779.1 | HEPN family nuclease | - |
| PXG74_RS28600 (PXG74_28600) | 51367..52146 | + | 780 | WP_013023780.1 | hypothetical protein | - |
| PXG74_RS28605 (PXG74_28605) | 52422..53945 | + | 1524 | WP_017899887.1 | hypothetical protein | - |
| PXG74_RS28610 (PXG74_28610) | 53979..55106 | + | 1128 | WP_013023782.1 | DUF4238 domain-containing protein | - |
| PXG74_RS28615 (PXG74_28615) | 55103..55393 | + | 291 | WP_013023783.1 | hypothetical protein | - |
| PXG74_RS28620 (PXG74_28620) | 56211..56429 | + | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| PXG74_RS28625 (PXG74_28625) | 56431..56736 | + | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| PXG74_RS28630 (PXG74_28630) | 56905..57300 | + | 396 | WP_017899885.1 | hypothetical protein | - |
| PXG74_RS28635 (PXG74_28635) | 57327..57641 | + | 315 | WP_053389906.1 | hypothetical protein | - |
| PXG74_RS28640 (PXG74_28640) | 57652..58668 | + | 1017 | WP_017899884.1 | hypothetical protein | - |
| PXG74_RS28645 (PXG74_28645) | 58866..59660 | + | 795 | WP_004197635.1 | site-specific integrase | - |
| PXG74_RS28650 (PXG74_28650) | 60124..60426 | - | 303 | WP_004197636.1 | hypothetical protein | - |
| PXG74_RS28655 (PXG74_28655) | 60423..61049 | - | 627 | WP_004197649.1 | hypothetical protein | VF |
| PXG74_RS28660 (PXG74_28660) | 61714..62589 | - | 876 | WP_004098982.1 | replication initiation protein | - |
| PXG74_RS28665 (PXG74_28665) | 63001..64272 | - | 1272 | WP_004197646.1 | Y-family DNA polymerase | - |
| PXG74_RS28670 (PXG74_28670) | 64272..64703 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| PXG74_RS28675 (PXG74_28675) | 64937..65908 | + | 972 | WP_001568038.1 | plasmid segregation protein ParM | - |
| PXG74_RS28680 (PXG74_28680) | 65911..66582 | + | 672 | WP_015345000.1 | plasmid partitioning/stability family protein | - |
| PXG74_RS28685 (PXG74_28685) | 66646..66876 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| PXG74_RS28690 (PXG74_28690) | 67072..67241 | + | 170 | Protein_81 | hypothetical protein | - |
| PXG74_RS28695 (PXG74_28695) | 67313..68014 | + | 702 | WP_001568041.1 | DNA methylase | - |
| PXG74_RS28700 (PXG74_28700) | 68014..68235 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| PXG74_RS28705 (PXG74_28705) | 68245..68664 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| PXG74_RS28710 (PXG74_28710) | 68718..69485 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| PXG74_RS28715 (PXG74_28715) | 70166..70594 | + | 429 | WP_004152356.1 | antirestriction protein | - |
| PXG74_RS28720 (PXG74_28720) | 70637..71143 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| PXG74_RS28725 (PXG74_28725) | 71186..71377 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| PXG74_RS28730 (PXG74_28730) | 71565..71819 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| PXG74_RS28735 (PXG74_28735) | 71854..72174 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| PXG74_RS28740 (PXG74_28740) | 72854..73081 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| PXG74_RS28745 (PXG74_28745) | 73173..73403 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| PXG74_RS28750 (PXG74_28750) | 73455..74810 | + | 1356 | WP_015344996.1 | DUF3560 domain-containing protein | - |
| PXG74_RS28755 (PXG74_28755) | 74858..75421 | + | 564 | WP_004152756.1 | methyltransferase | - |
| PXG74_RS28760 (PXG74_28760) | 76251..76793 | + | 543 | WP_015344994.1 | single-stranded DNA-binding protein | - |
| PXG74_RS28765 (PXG74_28765) | 76842..77090 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| PXG74_RS28770 (PXG74_28770) | 77160..79217 | + | 2058 | WP_065519831.1 | ParB/RepB/Spo0J family partition protein | - |
| PXG74_RS28775 (PXG74_28775) | 79262..79693 | + | 432 | WP_013023806.1 | conjugation system SOS inhibitor PsiB | - |
| PXG74_RS28780 (PXG74_28780) | 79690..80418 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| PXG74_RS28785 (PXG74_28785) | 80415..80741 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| PXG74_RS28790 (PXG74_28790) | 80797..81171 | + | 375 | WP_047665807.1 | hypothetical protein | - |
| PXG74_RS28795 (PXG74_28795) | 81341..81493 | + | 153 | WP_004150508.1 | DUF5431 family protein | - |
| PXG74_RS28800 (PXG74_28800) | 81438..81557 | + | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| PXG74_RS28805 (PXG74_28805) | 82250..82522 | + | 273 | WP_014343506.1 | hypothetical protein | - |
| PXG74_RS28810 (PXG74_28810) | 82519..82869 | + | 351 | WP_013023809.1 | hypothetical protein | - |
| PXG74_RS28815 (PXG74_28815) | 82884..83201 | + | 318 | WP_013023810.1 | hypothetical protein | - |
| PXG74_RS28820 (PXG74_28820) | 84043..84399 | + | 357 | WP_013023814.1 | hypothetical protein | - |
| PXG74_RS28825 (PXG74_28825) | 84460..84672 | + | 213 | WP_013023815.1 | hypothetical protein | - |
| PXG74_RS28830 (PXG74_28830) | 84683..84907 | + | 225 | WP_004152719.1 | hypothetical protein | - |
| PXG74_RS28835 (PXG74_28835) | 84988..85308 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PXG74_RS28840 (PXG74_28840) | 85298..85576 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| PXG74_RS28845 (PXG74_28845) | 85577..85990 | + | 414 | WP_013023817.1 | helix-turn-helix domain-containing protein | - |
| PXG74_RS28850 (PXG74_28850) | 86126..87334 | - | 1209 | WP_047665806.1 | IS256 family transposase ISEic2 | Transposase |
| PXG74_RS28855 (PXG74_28855) | 88142..88963 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| PXG74_RS28860 (PXG74_28860) | 88996..89325 | + | 330 | WP_011977736.1 | DUF5983 family protein | - |
| PXG74_RS28865 (PXG74_28865) | 89358..89843 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| PXG74_RS28870 (PXG74_28870) | 90275..90667 | + | 393 | WP_004194114.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PXG74_RS28875 (PXG74_28875) | 90897..91598 | + | 702 | WP_004194113.1 | hypothetical protein | - |
| PXG74_RS28880 (PXG74_28880) | 91684..91884 | + | 201 | WP_004194116.1 | TraY domain-containing protein | - |
| PXG74_RS28885 (PXG74_28885) | 91953..92321 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| PXG74_RS28890 (PXG74_28890) | 92335..92640 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| PXG74_RS28895 (PXG74_28895) | 92660..93226 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| PXG74_RS28900 (PXG74_28900) | 93213..93953 | + | 741 | WP_013023821.1 | type-F conjugative transfer system secretin TraK | - |
| PXG74_RS28905 (PXG74_28905) | 93953..95377 | + | 1425 | WP_004194260.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PXG74_RS28910 (PXG74_28910) | 95491..96075 | + | 585 | WP_013023822.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PXG74_RS28915 (PXG74_28915) | 96207..96617 | + | 411 | WP_009309869.1 | hypothetical protein | - |
| PXG74_RS28920 (PXG74_28920) | 96723..96941 | + | 219 | WP_015344987.1 | hypothetical protein | - |
| PXG74_RS28925 (PXG74_28925) | 96942..97253 | + | 312 | WP_015344986.1 | hypothetical protein | - |
| PXG74_RS28930 (PXG74_28930) | 97320..97724 | + | 405 | WP_004197817.1 | hypothetical protein | - |
| PXG74_RS28935 (PXG74_28935) | 98100..98498 | + | 399 | WP_013609531.1 | hypothetical protein | - |
| PXG74_RS28940 (PXG74_28940) | 98570..101209 | + | 2640 | WP_013023824.1 | type IV secretion system protein TraC | - |
| PXG74_RS28945 (PXG74_28945) | 101209..101598 | + | 390 | WP_004197815.1 | type-F conjugative transfer system protein TrbI | - |
| PXG74_RS28950 (PXG74_28950) | 101598..102224 | + | 627 | WP_009309871.1 | type-F conjugative transfer system protein TraW | - |
| PXG74_RS28955 (PXG74_28955) | 102266..102655 | + | 390 | WP_004194992.1 | hypothetical protein | - |
| PXG74_RS28960 (PXG74_28960) | 102652..103641 | + | 990 | WP_009309872.1 | conjugal transfer pilus assembly protein TraU | - |
| PXG74_RS28965 (PXG74_28965) | 103654..104292 | + | 639 | WP_011977786.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PXG74_RS28970 (PXG74_28970) | 104351..106306 | + | 1956 | WP_013023827.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PXG74_RS28975 (PXG74_28975) | 106338..106592 | + | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| PXG74_RS28980 (PXG74_28980) | 106570..106818 | + | 249 | WP_004152675.1 | hypothetical protein | - |
| PXG74_RS28985 (PXG74_28985) | 106831..107157 | + | 327 | WP_004152676.1 | hypothetical protein | - |
| PXG74_RS28990 (PXG74_28990) | 107178..107930 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PXG74_RS28995 (PXG74_28995) | 107941..108180 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PXG74_RS29000 (PXG74_29000) | 108152..108709 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PXG74_RS29005 (PXG74_29005) | 108755..109198 | + | 444 | WP_014343488.1 | F-type conjugal transfer protein TrbF | - |
| PXG74_RS29010 (PXG74_29010) | 109176..110555 | + | 1380 | WP_014343487.1 | conjugal transfer pilus assembly protein TraH | - |
| PXG74_RS29015 (PXG74_29015) | 110555..113404 | + | 2850 | WP_013609534.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PXG74_RS29020 (PXG74_29020) | 113407..113940 | + | 534 | WP_014343486.1 | conjugal transfer protein TraS | - |
| PXG74_RS29025 (PXG74_29025) | 114126..114857 | + | 732 | WP_013023830.1 | conjugal transfer complement resistance protein TraT | - |
| PXG74_RS29030 (PXG74_29030) | 115050..115739 | + | 690 | WP_013023831.1 | hypothetical protein | - |
| PXG74_RS29035 (PXG74_29035) | 115866..118178 | + | 2313 | WP_013023832.1 | type IV conjugative transfer system coupling protein TraD | - |
| PXG74_RS29040 (PXG74_29040) | 118178..123439 | + | 5262 | WP_047665818.1 | Multifunctional conjugation protein TraI | Relaxase |
| PXG74_RS29045 (PXG74_29045) | 123520..124245 | + | 726 | WP_013023834.1 | type-F conjugative transfer system pilin acetylase TraX | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|