MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 121841 bp
Accession: NZ_CP116930 Location: 1..121841 Organism: Escherichia coli strain MLI106K1 Replicon: plasmid p121_MLI106-1
Accession: NZ_CP116930 Location: 1..121841 Organism: Escherichia coli strain MLI106K1 Replicon: plasmid p121_MLI106-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NL422_RS00005 (NL422_000005) | 1..1011 | + | 1011 | WP_000200069.1 | RepB family plasmid replication initiator protein | - |
| NL422_RS00010 (NL422_000010) | 1823..2146 | - | 324 | Protein_1 | lipocalin family protein | - |
| NL422_RS00015 (NL422_000015) | 2264..2989 | + | 726 | WP_000331736.1 | IS607 family transposase ISAfe11 | Transposase |
| NL422_RS00020 (NL422_000020) | 3089..3499 | + | 411 | WP_000750473.1 | hydroxyisourate hydrolase | - |
| NL422_RS00025 (NL422_000025) | 3602..4561 | + | 960 | WP_000208728.1 | DUF523 and DUF1722 domain-containing protein | - |
| NL422_RS00030 (NL422_000030) | 4707..5810 | + | 1104 | WP_225568148.1 | AAA family ATPase | - |
| NL422_RS00035 (NL422_000035) | 5756..6460 | - | 705 | WP_001067852.1 | IS6 family transposase IS26 | Transposase |
| NL422_RS00040 (NL422_000040) | 6451..6939 | + | 489 | WP_072075272.1 | replication initiation protein | - |
| NL422_RS00045 (NL422_000045) | 8897..9466 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| NL422_RS00050 (NL422_000050) | 9859..10872 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| NL422_RS00055 (NL422_000055) | 11028..11501 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| NL422_RS00060 (NL422_000060) | 11748..12452 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NL422_RS00065 (NL422_000065) | 12343..13068 | - | 726 | WP_272795875.1 | hypothetical protein | VF |
| NL422_RS00070 (NL422_000070) | 13078..13377 | - | 300 | WP_000175462.1 | TrbC/VirB2 family protein | - |
| NL422_RS00075 (NL422_000075) | 13388..14050 | - | 663 | WP_000958205.1 | hypothetical protein | VF |
| NL422_RS00080 (NL422_000080) | 14053..14268 | - | 216 | WP_001112907.1 | hypothetical protein | - |
| NL422_RS00085 (NL422_000085) | 14261..14569 | - | 309 | WP_000062770.1 | hypothetical protein | - |
| NL422_RS00090 (NL422_000090) | 14892..15797 | + | 906 | WP_011264037.1 | helix-turn-helix domain-containing protein | - |
| NL422_RS00095 (NL422_000095) | 15801..16784 | + | 984 | WP_032201035.1 | hypothetical protein | - |
| NL422_RS00100 (NL422_000100) | 16777..17265 | + | 489 | WP_000238872.1 | molybdopterin-dependent oxidoreductase | - |
| NL422_RS00105 (NL422_000105) | 17262..18980 | + | 1719 | WP_000739198.1 | hybrid sensor histidine kinase/response regulator | - |
| NL422_RS00110 (NL422_000110) | 19839..20196 | - | 358 | Protein_21 | IS1 family transposase IS1X4 | Transposase |
| NL422_RS00115 (NL422_000115) | 20388..21365 | + | 978 | WP_000600827.1 | IS91 family transposase ISWz1 | Transposase |
| NL422_RS00120 (NL422_000120) | 21413..21676 | - | 264 | WP_001531263.1 | hypothetical protein | - |
| NL422_RS00125 (NL422_000125) | 21711..24677 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NL422_RS00130 (NL422_000130) | 24681..25241 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| NL422_RS00135 (NL422_000135) | 25551..27128 | + | 1578 | WP_001323889.1 | Aerotaxis receptor | VF |
| NL422_RS00140 (NL422_000140) | 27220..27712 | + | 493 | Protein_27 | IS1 family transposase IS1X2 | Transposase |
| NL422_RS00145 (NL422_000145) | 27864..29861 | + | 1998 | WP_032213821.1 | choline BCCT transporter BetT | - |
| NL422_RS00150 (NL422_000150) | 29924..31201 | + | 1278 | WP_053921605.1 | DUF2254 domain-containing protein | - |
| NL422_RS00160 (NL422_000160) | 31974..32333 | - | 360 | Protein_31 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| NL422_RS00165 (NL422_000165) | 32493..33077 | + | 585 | WP_053921599.1 | Tn3 family transposase TnpR_ISYps3 | Transposase |
| NL422_RS00170 (NL422_000170) | 33466..34944 | + | 1479 | WP_000927305.1 | SulP family inorganic anion transporter | - |
| NL422_RS00175 (NL422_000175) | 34963..35790 | + | 828 | WP_053921598.1 | universal stress protein | - |
| NL422_RS00180 (NL422_000180) | 35989..36993 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| NL422_RS00185 (NL422_000185) | 37260..37454 | + | 195 | Protein_36 | helix-turn-helix domain-containing protein | - |
| NL422_RS00190 (NL422_000190) | 37645..38202 | + | 558 | WP_053921594.1 | OsmC family protein | - |
| NL422_RS00195 (NL422_000195) | 38344..38925 | + | 582 | WP_000210408.1 | HTH-type transcriptional repressor NemR | VF |
| NL422_RS00200 (NL422_000200) | 38930..39268 | + | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| NL422_RS00205 (NL422_000205) | 39383..39628 | - | 246 | WP_225568153.1 | thioredoxin family protein | - |
| NL422_RS00210 (NL422_000210) | 39842..40948 | + | 1107 | WP_006687059.1 | alkene reductase | - |
| NL422_RS00215 (NL422_000215) | 41014..41715 | + | 702 | WP_001194072.1 | DsbA family oxidoreductase | - |
| NL422_RS00220 (NL422_000220) | 41781..42554 | + | 774 | WP_001091225.1 | SDR family oxidoreductase | - |
| NL422_RS00225 (NL422_000225) | 42740..43714 | - | 975 | WP_072164305.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| NL422_RS00230 (NL422_000230) | 43792..43989 | + | 198 | WP_024262939.1 | alpha/beta hydrolase | - |
| NL422_RS00235 (NL422_000235) | 44043..44329 | + | 287 | Protein_46 | Tn3 family transposase | - |
| NL422_RS00240 (NL422_000240) | 44429..45433 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| NL422_RS00245 (NL422_000245) | 46099..46221 | + | 123 | Protein_48 | serine/threonine protein kinase | - |
| NL422_RS00250 (NL422_000250) | 46342..47082 | + | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| NL422_RS00255 (NL422_000255) | 47361..48338 | - | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| NL422_RS00260 (NL422_000260) | 49095..50067 | + | 973 | Protein_51 | hypothetical protein | - |
| NL422_RS00265 (NL422_000265) | 50226..50582 | - | 357 | WP_225568154.1 | abortive infection family protein | - |
| NL422_RS00270 (NL422_000270) | 50662..51359 | + | 698 | WP_226458177.1 | IS1 family transposase IS1G | Transposase |
| NL422_RS00275 (NL422_000275) | 51376..51723 | + | 348 | Protein_54 | ABC transporter permease subunit | - |
| NL422_RS00280 (NL422_000280) | 51735..52781 | + | 1047 | WP_000192349.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | VF |
| NL422_RS00285 (NL422_000285) | 52890..53822 | - | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| NL422_RS00290 (NL422_000290) | 53809..55212 | - | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| NL422_RS00295 (NL422_000295) | 55456..56436 | + | 981 | Protein_58 | IS5 family transposase IS5D | Transposase |
| NL422_RS00300 (NL422_000300) | 56646..56981 | + | 336 | WP_169329198.1 | type I deoxyribonuclease HsdR | - |
| NL422_RS00305 (NL422_000305) | 56931..57344 | - | 414 | Protein_60 | IS3 family transposase ISLad1 | Transposase |
| NL422_RS00310 (NL422_000310) | 57349..57627 | - | 279 | Protein_61 | pdcB | - |
| NL422_RS00315 (NL422_000315) | 57655..57834 | - | 180 | WP_001513661.1 | hypothetical protein | - |
| NL422_RS00320 (NL422_000320) | 57839..58219 | - | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| NL422_RS00325 (NL422_000325) | 58219..58440 | - | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| NL422_RS00330 (NL422_000330) | 58703..59400 | + | 698 | WP_226458177.1 | IS1 family transposase IS1G | Transposase |
| NL422_RS00335 (NL422_000335) | 59587..59880 | - | 294 | WP_226438991.1 | biofilm development regulator YmgB/AriR family protein | - |
| NL422_RS00340 (NL422_000340) | 60184..60288 | - | 105 | Protein_67 | IS3 family transposase | - |
| NL422_RS00345 (NL422_000345) | 60315..60464 | - | 150 | Protein_68 | IS3 family transposase | - |
| NL422_RS00355 (NL422_000355) | 61678..62292 | + | 615 | WP_032214276.1 | acid-sensing system DNA-binding response regulator EvgA | - |
| NL422_RS00360 (NL422_000360) | 62297..65890 | + | 3594 | WP_072617410.1 | acid-sensing system histidine kinase EvgS | - |
| NL422_RS00365 (NL422_000365) | 66006..66313 | + | 308 | Protein_72 | IS1-like element transposase | - |
| NL422_RS00370 (NL422_000370) | 66347..67897 | - | 1551 | Protein_73 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NL422_RS00375 (NL422_000375) | 67952..68656 | - | 705 | WP_001067852.1 | IS6 family transposase IS26 | Transposase |
| NL422_RS00380 (NL422_000380) | 68920..69993 | - | 1074 | WP_000557466.1 | hypothetical protein | - |
| NL422_RS00385 (NL422_000385) | 70037..70186 | - | 150 | WP_000550473.1 | hypothetical protein | - |
| NL422_RS00390 (NL422_000390) | 70393..70503 | - | 111 | Protein_77 | protein YdfV | - |
| NL422_RS00395 (NL422_000395) | 70528..70767 | + | 240 | WP_000534857.1 | type II toxin-antitoxin system antitoxin RelB | - |
| NL422_RS00400 (NL422_000400) | 70767..70928 | + | 162 | Protein_79 | type II toxin-antitoxin system mRNA interferase RelE | - |
| NL422_RS00405 (NL422_000405) | 71063..71608 | + | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| NL422_RS00410 (NL422_000410) | 71745..72317 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| NL422_RS00415 (NL422_000415) | 72354..73745 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| NL422_RS00420 (NL422_000420) | 73778..74206 | + | 429 | Protein_83 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| NL422_RS00425 (NL422_000425) | 74525..75181 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| NL422_RS00430 (NL422_000430) | 75576..76591 | + | 1016 | Protein_85 | IS3 family transposase ISEc36 | Transposase |
| NL422_RS00435 (NL422_000435) | 76634..79417 | - | 2784 | Protein_86 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NL422_RS00440 (NL422_000440) | 79443..79775 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| NL422_RS00445 (NL422_000445) | 79822..80697 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| NL422_RS00450 (NL422_000450) | 80953..82214 | - | 1262 | Protein_89 | IS1380 family transposase ISEcp1 | Transposase |
| NL422_RS00455 (NL422_000455) | 82396..82614 | - | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NL422_RS00460 (NL422_000460) | 82778..83335 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NL422_RS00465 (NL422_000465) | 83518..84378 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NL422_RS00470 (NL422_000470) | 85001..85654 | + | 654 | Protein_93 | EamA family transporter | - |
| NL422_RS00475 (NL422_000475) | 85686..86885 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| NL422_RS00480 (NL422_000480) | 86991..87641 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| NL422_RS00485 (NL422_000485) | 87673..87915 | - | 243 | WP_024203663.1 | hypothetical protein | - |
| NL422_RS00490 (NL422_000490) | 88364..88768 | + | 405 | Protein_97 | IS91 family transposase ISPps1 | Transposase |
| NL422_RS00495 (NL422_000495) | 88875..89711 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| NL422_RS00500 (NL422_000500) | 89711..90514 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| NL422_RS00505 (NL422_000505) | 90575..91390 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| NL422_RS00510 (NL422_000510) | 91720..91806 | + | 87 | Protein_101 | Arm DNA-binding domain-containing protein | - |
| NL422_RS00515 (NL422_000515) | 92078..93082 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| NL422_RS00520 (NL422_000520) | 93161..94927 | - | 1767 | Protein_103 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| NL422_RS00525 (NL422_000525) | 94979..95683 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NL422_RS00530 (NL422_000530) | 95674..97851 | + | 2178 | WP_272795874.1 | Type IV secretion system protein virB4 | VF |
| NL422_RS00535 (NL422_000535) | 97870..98586 | + | 717 | WP_000770034.1 | type IV secretion system protein | - |
| NL422_RS00540 (NL422_000540) | 98598..98882 | + | 285 | WP_000769859.1 | EexN family lipoprotein | - |
| NL422_RS00545 (NL422_000545) | 98900..99907 | + | 1008 | WP_032201037.1 | type IV secretion system protein | - |
| NL422_RS00550 (NL422_000550) | 99984..100124 | + | 141 | WP_000873539.1 | hypothetical protein | - |
| NL422_RS00555 (NL422_000555) | 100117..100803 | + | 687 | WP_001293055.1 | type IV secretion system protein | - |
| NL422_RS00560 (NL422_000560) | 100796..101689 | + | 894 | WP_001045307.1 | P-type conjugative transfer protein VirB9 | - |
| NL422_RS00565 (NL422_000565) | 101686..102882 | + | 1197 | WP_000980841.1 | hypothetical protein | VF |
| NL422_RS00570 (NL422_000570) | 102886..103935 | + | 1050 | WP_000342114.1 | Type IV secretion system protein VirB11 | VF |
| NL422_RS00575 (NL422_000575) | 103922..104323 | + | 402 | WP_000979494.1 | cag pathogenicity island Cag12 family protein | - |
| NL422_RS00580 (NL422_000580) | 104414..104731 | + | 318 | WP_000683352.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| NL422_RS00585 (NL422_000585) | 104758..105093 | + | 336 | WP_000610141.1 | hypothetical protein | - |
| NL422_RS00590 (NL422_000590) | 105069..105377 | + | 309 | WP_000212005.1 | hypothetical protein | - |
| NL422_RS00595 (NL422_000595) | 105374..107575 | + | 2202 | WP_001241818.1 | type IA DNA topoisomerase | - |
| NL422_RS00600 (NL422_000600) | 107572..107964 | + | 393 | WP_001079960.1 | H-NS family nucleoid-associated regulatory protein | - |
| NL422_RS00605 (NL422_000605) | 108673..110580 | + | 1908 | WP_000575554.1 | type IV secretion system DNA-binding domain-containing protein | - |
| NL422_RS00610 (NL422_000610) | 110595..111341 | + | 747 | WP_000909125.1 | MobC family replication-relaxation protein | - |
| NL422_RS00615 (NL422_000615) | 111334..111861 | + | 528 | WP_001232861.1 | Cardiolipin synthase B | VF |
| NL422_RS00620 (NL422_000620) | 111893..112324 | - | 432 | WP_001531161.1 | hypothetical protein | - |
| NL422_RS00625 (NL422_000625) | 112456..112632 | - | 177 | WP_013438824.1 | hypothetical protein | - |
| NL422_RS00630 (NL422_000630) | 112804..113769 | - | 966 | WP_001743098.1 | zincin-like metallopeptidase domain-containing protein | - |
| NL422_RS00635 (NL422_000635) | 114224..115444 | - | 1221 | Protein_126 | ISL3 family transposase ISKox3 | Transposase |
| NL422_RS00640 (NL422_000640) | 115545..115970 | + | 426 | WP_000668788.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NL422_RS00645 (NL422_000645) | 115970..117241 | + | 1272 | WP_000457544.1 | Y-family DNA polymerase | - |
| NL422_RS00650 (NL422_000650) | 117320..117571 | + | 252 | WP_000181753.1 | hypothetical protein | - |
| NL422_RS00655 (NL422_000655) | 117625..117930 | + | 306 | WP_000534920.1 | hypothetical protein | - |
| NL422_RS00660 (NL422_000660) | 118964..119935 | - | 972 | WP_000817037.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NL422_RS00665 (NL422_000665) | 119935..121101 | - | 1167 | WP_000523812.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|