MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 158971 bp
Accession: NZ_CP116547 Location: 1..158971 Organism: Enterococcus faecium strain K189-3 Replicon: plasmid pK189-3-A
Accession: NZ_CP116547 Location: 1..158971 Organism: Enterococcus faecium strain K189-3 Replicon: plasmid pK189-3-A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PML74_RS12835 (PML74_12835) | 1..1041 | + | 1041 | WP_002297425.1 | replication initiator protein A | - |
PML74_RS12840 (PML74_12840) | 1880..2212 | + | 333 | WP_002322486.1 | type IV conjugative transfer system protein TraE | - |
PML74_RS12845 (PML74_12845) | 2831..3172 | + | 342 | Protein_2 | DUF5406 family protein | - |
PML74_RS12850 (PML74_12850) | 3286..3525 | + | 240 | WP_002331333.1 | hypothetical protein | - |
PML74_RS12855 (PML74_12855) | 3592..3792 | + | 201 | WP_002331334.1 | hypothetical protein | - |
PML74_RS12860 (PML74_12860) | 3845..4525 | + | 681 | WP_002331335.1 | IS6 family transposase IS1216E | Transposase |
PML74_RS12865 (PML74_12865) | 5131..5532 | + | 402 | WP_002299892.1 | IS200-IS605 family transposase ISBce3 | Transposase |
PML74_RS12870 (PML74_12870) | 5556..6674 | + | 1119 | WP_002320593.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
PML74_RS12875 (PML74_12875) | 6870..7541 | + | 672 | WP_002331336.1 | class A sortase | - |
PML74_RS12880 (PML74_12880) | 7593..9569 | + | 1977 | WP_002331337.1 | SpaA isopeptide-forming pilin-related protein | - |
PML74_RS12885 (PML74_12885) | 9584..10336 | + | 753 | WP_002331338.1 | Sortase A | VF |
PML74_RS12890 (PML74_12890) | 10352..11107 | + | 756 | WP_002331339.1 | pilin N-terminal domain-containing protein | - |
PML74_RS12895 (PML74_12895) | 11120..11380 | + | 261 | WP_002331340.1 | hypothetical protein | - |
PML74_RS12900 (PML74_12900) | 11377..13467 | + | 2091 | WP_002331341.1 | isopeptide-forming domain-containing fimbrial protein | - |
PML74_RS12905 (PML74_12905) | 13494..13958 | + | 465 | WP_025477660.1 | hypothetical protein | - |
PML74_RS12910 (PML74_12910) | 13955..14197 | + | 243 | WP_002305229.1 | DUF5415 family protein | - |
PML74_RS12915 (PML74_12915) | 14215..14517 | + | 303 | WP_002295662.1 | hypothetical protein | - |
PML74_RS12920 (PML74_12920) | 14587..16662 | + | 2076 | WP_002331343.1 | hypothetical protein | - |
PML74_RS12925 (PML74_12925) | 16662..19271 | + | 2610 | WP_002331344.1 | type IV secretory system conjugative DNA transfer family protein | - |
PML74_RS12930 (PML74_12930) | 19268..21634 | + | 2367 | WP_002331345.1 | hypothetical protein | - |
PML74_RS12935 (PML74_12935) | 21686..22018 | + | 333 | WP_002295656.1 | hypothetical protein | - |
PML74_RS12940 (PML74_12940) | 22019..22612 | + | 594 | WP_002331346.1 | hypothetical protein | - |
PML74_RS12945 (PML74_12945) | 22775..24799 | + | 2025 | WP_272019710.1 | ATPase | - |
PML74_RS12950 (PML74_12950) | 24799..26004 | + | 1206 | WP_002331349.1 | glucosaminidase domain-containing protein | - |
PML74_RS12955 (PML74_12955) | 26020..26670 | + | 651 | WP_002297495.1 | hypothetical protein | - |
PML74_RS12960 (PML74_12960) | 26681..27487 | + | 807 | WP_002331350.1 | hypothetical protein | - |
PML74_RS12965 (PML74_12965) | 27510..27740 | + | 231 | WP_002297493.1 | hypothetical protein | - |
PML74_RS12970 (PML74_12970) | 27898..28833 | + | 936 | WP_002297492.1 | hypothetical protein | - |
PML74_RS12975 (PML74_12975) | 28877..29146 | + | 270 | WP_002331351.1 | hypothetical protein | - |
PML74_RS12980 (PML74_12980) | 29356..29643 | + | 288 | WP_002331352.1 | hypothetical protein | - |
PML74_RS12985 (PML74_12985) | 29661..30083 | + | 423 | WP_002331353.1 | hypothetical protein | - |
PML74_RS12990 (PML74_12990) | 30103..31695 | + | 1593 | WP_033624447.1 | hypothetical protein | Relaxase |
PML74_RS12995 (PML74_12995) | 31707..32042 | + | 336 | WP_002331355.1 | hypothetical protein | - |
PML74_RS13000 (PML74_13000) | 32189..32383 | + | 195 | WP_002302840.1 | hypothetical protein | - |
PML74_RS13005 (PML74_13005) | 32519..33769 | - | 1251 | WP_002287107.1 | IS110 family transposase ISSpn10 | Transposase |
PML74_RS13010 (PML74_13010) | 34179..36551 | + | 2373 | WP_002331356.1 | ArdC-like ssDNA-binding domain-containing protein | - |
PML74_RS13015 (PML74_13015) | 36612..38081 | + | 1470 | Protein_36 | toprim domain-containing protein | - |
PML74_RS13020 (PML74_13020) | 38092..40296 | + | 2205 | WP_002331358.1 | type IA DNA topoisomerase | - |
PML74_RS13025 (PML74_13025) | 40312..40461 | + | 150 | WP_002295632.1 | hypothetical protein | - |
PML74_RS13030 (PML74_13030) | 40542..41138 | + | 597 | WP_002299811.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
PML74_RS13035 (PML74_13035) | 41151..42050 | + | 900 | WP_002299810.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
PML74_RS13040 (PML74_13040) | 42053..42538 | + | 486 | WP_002295626.1 | single-stranded DNA-binding protein | - |
PML74_RS13045 (PML74_13045) | 42560..42817 | + | 258 | WP_002299808.1 | hypothetical protein | - |
PML74_RS13050 (PML74_13050) | 42976..43120 | - | 145 | Protein_43 | putative holin-like toxin | - |
PML74_RS13055 (PML74_13055) | 43253..43513 | + | 261 | WP_002299806.1 | hypothetical protein | - |
PML74_RS13060 (PML74_13060) | 43962..44168 | + | 207 | WP_002330430.1 | hypothetical protein | - |
PML74_RS13065 (PML74_13065) | 44168..44419 | + | 252 | WP_002300797.1 | hypothetical protein | - |
PML74_RS13070 (PML74_13070) | 44435..44590 | + | 156 | WP_002300799.1 | hypothetical protein | - |
PML74_RS13075 (PML74_13075) | 44600..44872 | + | 273 | WP_002300801.1 | hypothetical protein | - |
PML74_RS13080 (PML74_13080) | 45317..45496 | + | 180 | WP_002300804.1 | hypothetical protein | - |
PML74_RS13085 (PML74_13085) | 45555..45911 | + | 357 | WP_002311569.1 | hypothetical protein | - |
PML74_RS13090 (PML74_13090) | 46880..47833 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
PML74_RS13095 (PML74_13095) | 47954..48217 | + | 264 | WP_002300807.1 | uberolysin/carnocyclin family circular bacteriocin | - |
PML74_RS13100 (PML74_13100) | 48589..49767 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
PML74_RS13105 (PML74_13105) | 50155..52101 | + | 1947 | WP_002300833.1 | PTS sugar transporter subunit IIA | - |
PML74_RS13110 (PML74_13110) | 52104..52559 | + | 456 | WP_002300835.1 | PTS sugar transporter subunit IIA | - |
PML74_RS13115 (PML74_13115) | 52573..53901 | + | 1329 | WP_002300836.1 | PTS transporter subunit IIC | - |
PML74_RS13120 (PML74_13120) | 53935..54219 | + | 285 | WP_002300838.1 | PTS sugar transporter subunit IIB | - |
PML74_RS13125 (PML74_13125) | 54221..54736 | + | 516 | WP_002300840.1 | YjbQ family protein | - |
PML74_RS13130 (PML74_13130) | 54752..55414 | + | 663 | WP_002300841.1 | Ribulose-phosphate 3-epimerase | VF |
PML74_RS13135 (PML74_13135) | 55421..55993 | + | 573 | WP_002300842.1 | 3-hexulose-6-phosphate isomerase | VF |
PML74_RS13140 (PML74_13140) | 56180..57700 | - | 1521 | WP_002300843.1 | IS66 family transposase ISDeal1 | Transposase |
PML74_RS13145 (PML74_13145) | 57943..58128 | - | 186 | WP_002305884.1 | IS66 family transposase ISEbi1 | Transposase |
PML74_RS13150 (PML74_13150) | 58112..58294 | - | 183 | WP_002300846.1 | hypothetical protein | - |
PML74_RS13155 (PML74_13155) | 58535..58753 | + | 219 | Protein_64 | IS256 family transposase ISLgar5 | Transposase |
PML74_RS13160 (PML74_13160) | 59248..59847 | + | 600 | WP_002301839.1 | Tyrosine recombinase XerC | VF |
PML74_RS13165 (PML74_13165) | 59911..60510 | + | 600 | WP_002322465.1 | AbiH family protein | - |
PML74_RS13170 (PML74_13170) | 60540..61191 | - | 652 | Protein_67 | IS6 family transposase IS1216V | Transposase |
PML74_RS13175 (PML74_13175) | 61526..62398 | - | 873 | WP_002305879.1 | ROK family protein | - |
PML74_RS13180 (PML74_13180) | 62662..64608 | - | 1947 | WP_002352509.1 | sucrose-specific PTS transporter subunit IIBC | - |
PML74_RS13185 (PML74_13185) | 64793..66232 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
PML74_RS13190 (PML74_13190) | 66234..67196 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
PML74_RS13195 (PML74_13195) | 67366..68792 | - | 1427 | Protein_72 | IS3 family transposase ISEfa10 | Transposase |
PML74_RS13200 (PML74_13200) | 69035..69490 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
PML74_RS13205 (PML74_13205) | 69755..69853 | + | 99 | Protein_74 | IS30 family transposase | - |
PML74_RS13210 (PML74_13210) | 70076..70306 | - | 231 | WP_002289255.1 | resolvase | - |
PML74_RS13215 (PML74_13215) | 70536..71354 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
PML74_RS13220 (PML74_13220) | 71515..72204 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
PML74_RS13225 (PML74_13225) | 72218..73720 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
PML74_RS13230 (PML74_13230) | 73733..74209 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
PML74_RS13240 (PML74_13240) | 76987..77505 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
PML74_RS13245 (PML74_13245) | 79581..80666 | + | 1086 | WP_002301591.1 | tyrosine recombinase XerS | - |
PML74_RS13250 (PML74_13250) | 80774..81727 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
PML74_RS13255 (PML74_13255) | 81858..83108 | - | 1251 | WP_002301126.1 | PTS sugar transporter subunit IIC | - |
PML74_RS13260 (PML74_13260) | 83127..84053 | - | 927 | WP_002298736.1 | PEP phosphonomutase | - |
PML74_RS13265 (PML74_13265) | 84132..85127 | - | 996 | WP_002301128.1 | tagatose-bisphosphate aldolase | - |
PML74_RS13270 (PML74_13270) | 85143..86312 | - | 1170 | WP_002301130.1 | SIS domain-containing protein | - |
PML74_RS13275 (PML74_13275) | 86328..87062 | - | 735 | WP_002301131.1 | GntR family transcriptional regulator | - |
PML74_RS13285 (PML74_13285) | 89254..90593 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
PML74_RS13290 (PML74_13290) | 90984..92276 | - | 1293 | WP_002301811.1 | IS256 family transposase ISBsu2 | Transposase |
PML74_RS13295 (PML74_13295) | 92550..92810 | - | 261 | WP_002313174.1 | hypothetical protein | - |
PML74_RS13300 (PML74_13300) | 93061..94239 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
PML74_RS13305 (PML74_13305) | 94537..94827 | + | 291 | Protein_94 | DDE-type integrase/transposase/recombinase | - |
PML74_RS13310 (PML74_13310) | 94810..95690 | - | 881 | Protein_95 | IS3 family transposase ISEfa8 | Transposase |
PML74_RS13315 (PML74_13315) | 95892..96287 | - | 396 | WP_002287876.1 | aspartate 1-decarboxylase | - |
PML74_RS13320 (PML74_13320) | 96297..97145 | - | 849 | WP_002287875.1 | pantoate--beta-alanine ligase | - |
PML74_RS13325 (PML74_13325) | 97160..97543 | - | 384 | Protein_98 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
PML74_RS13335 (PML74_13335) | 98910..99356 | - | 447 | Protein_100 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
PML74_RS13340 (PML74_13340) | 99368..100228 | - | 861 | WP_002349114.1 | Rossmann-like and DUF2520 domain-containing protein | - |
PML74_RS13345 (PML74_13345) | 100466..101635 | + | 1170 | WP_002300493.1 | IS256 family transposase ISEfa13 | Transposase |
PML74_RS13350 (PML74_13350) | 101960..103279 | - | 1320 | WP_002300494.1 | HAMP domain-containing sensor histidine kinase | - |
PML74_RS13355 (PML74_13355) | 103276..103929 | - | 654 | WP_002285815.1 | Transcriptional regulatory protein QseB | VF |
PML74_RS13360 (PML74_13360) | 104217..105150 | + | 934 | Protein_105 | ISL3 family transposase IS1476 | Transposase |
PML74_RS13365 (PML74_13365) | 105058..105873 | - | 816 | WP_002302255.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
PML74_RS13370 (PML74_13370) | 105824..106033 | - | 210 | WP_002302256.1 | hypothetical protein | - |
PML74_RS13375 (PML74_13375) | 106310..107542 | + | 1233 | Protein_108 | ISL3 family transposase ISEfa11 | Transposase |
PML74_RS13380 (PML74_13380) | 107690..108721 | - | 1032 | WP_002302261.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
PML74_RS13385 (PML74_13385) | 108728..109558 | - | 831 | WP_002313180.1 | ABC transporter permease | - |
PML74_RS13390 (PML74_13390) | 109555..110370 | - | 816 | WP_002330693.1 | ABC transporter permease subunit | - |
PML74_RS13395 (PML74_13395) | 110367..111191 | - | 825 | WP_002302267.1 | alkaline phosphatase family protein | - |
PML74_RS13400 (PML74_13400) | 111181..112281 | - | 1101 | WP_002302268.1 | extracellular solute-binding protein | - |
PML74_RS13405 (PML74_13405) | 112459..113244 | + | 786 | WP_002302270.1 | PHP domain-containing protein | - |
PML74_RS13410 (PML74_13410) | 113277..113660 | + | 384 | WP_002330694.1 | hypothetical protein | - |
PML74_RS13415 (PML74_13415) | 113836..114072 | + | 237 | WP_002322470.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase | VF |
PML74_RS13420 (PML74_13420) | 114084..114251 | + | 168 | WP_077828693.1 | peptidylprolyl isomerase | - |
PML74_RS13425 (PML74_13425) | 114373..115668 | - | 1296 | WP_002296623.1 | ISL3 family transposase IS1251 | Transposase |
PML74_RS13430 (PML74_13430) | 115739..116632 | - | 894 | WP_080114582.1 | radical SAM protein | - |
PML74_RS13435 (PML74_13435) | 117266..118726 | + | 1461 | Protein_120 | IS1182 family transposase ISEfa7 | Transposase |
PML74_RS13440 (PML74_13440) | 118649..118978 | - | 330 | WP_228780303.1 | IS1182 family transposase ISEfa7 | Transposase |
PML74_RS13445 (PML74_13445) | 119192..120568 | - | 1377 | WP_002301195.1 | ABC transporter permease | - |
PML74_RS13450 (PML74_13450) | 120568..121224 | - | 657 | WP_002298083.1 | putative ABC transporter ATP-binding protein | VF |
PML74_RS13455 (PML74_13455) | 121234..122511 | - | 1278 | WP_002301194.1 | ABC transporter permease | - |
PML74_RS13460 (PML74_13460) | 122530..122685 | - | 156 | Protein_125 | 4Fe-4S binding protein | - |
PML74_RS13465 (PML74_13465) | 122761..123923 | + | 1163 | WP_102829665.1 | IS3 family transposase ISEfa8 | Transposase |
PML74_RS13470 (PML74_13470) | 124029..124244 | + | 216 | Protein_127 | IS256 family transposase ISEf1 | Transposase |
PML74_RS13475 (PML74_13475) | 124535..125059 | - | 525 | WP_002352518.1 | hypothetical protein | - |
PML74_RS13480 (PML74_13480) | 125084..125992 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
PML74_RS13485 (PML74_13485) | 126061..126612 | - | 552 | WP_002330700.1 | hypothetical protein | - |
PML74_RS13490 (PML74_13490) | 126668..127222 | - | 555 | WP_002301108.1 | tyrosine-type recombinase/integrase | - |
PML74_RS13495 (PML74_13495) | 127628..128536 | - | 909 | WP_016925867.1 | IS982 family transposase ISEfm1 | Transposase |
PML74_RS13500 (PML74_13500) | 128744..129922 | - | 1179 | WP_002340536.1 | IS256 family transposase ISEfm2 | Transposase |
PML74_RS13505 (PML74_13505) | 130943..131428 | - | 486 | WP_080114350.1 | hypothetical protein | - |
PML74_RS13510 (PML74_13510) | 131504..132184 | - | 681 | WP_002328842.1 | IS6 family transposase IS1297 | Transposase |
PML74_RS13515 (PML74_13515) | 132518..133411 | + | 894 | WP_002316719.1 | neutral zinc metallopeptidase | - |
PML74_RS13525 (PML74_13525) | 133951..135236 | + | 1286 | Protein_137 | cytochrome P450 | - |
PML74_RS13530 (PML74_13530) | 135308..136933 | - | 1626 | WP_002331388.1 | peptide ABC transporter substrate-binding protein | - |
PML74_RS13535 (PML74_13535) | 137424..137873 | + | 450 | WP_002331389.1 | DIP1984 family protein | - |
PML74_RS13540 (PML74_13540) | 138190..138771 | - | 582 | WP_002331293.1 | IS630 family transposase ISBs2 | Transposase |
PML74_RS13545 (PML74_13545) | 138790..140133 | - | 1344 | WP_002332322.1 | PFL family protein | - |
PML74_RS13550 (PML74_13550) | 140148..140414 | - | 267 | WP_002290085.1 | ACT domain-containing protein | - |
PML74_RS13555 (PML74_13555) | 140517..141185 | - | 669 | WP_002331291.1 | 2,3-diphosphoglycerate-dependent phosphoglycerate mutase | - |
PML74_RS13560 (PML74_13560) | 141467..142327 | + | 861 | Protein_144 | MATE family efflux transporter | - |
PML74_RS13565 (PML74_13565) | 142327..142941 | - | 615 | Protein_145 | PTS beta-glucoside transporter subunit IIBC | - |
PML74_RS13570 (PML74_13570) | 142961..143203 | - | 243 | WP_002331325.1 | PTS sugar transporter subunit IIB | - |
PML74_RS13575 (PML74_13575) | 143308..143523 | - | 216 | Protein_147 | DDE-type integrase/transposase/recombinase | - |
PML74_RS13580 (PML74_13580) | 143688..144470 | - | 783 | WP_002331326.1 | hypothetical protein | - |
PML74_RS13585 (PML74_13585) | 144703..146505 | - | 1803 | WP_002331327.1 | exonuclease domain-containing protein | - |
PML74_RS13590 (PML74_13590) | 146568..147053 | - | 486 | WP_227326759.1 | hypothetical protein | - |
PML74_RS13595 (PML74_13595) | 147426..147647 | - | 222 | WP_002331328.1 | helix-turn-helix transcriptional regulator | - |
PML74_RS13600 (PML74_13600) | 147790..148119 | - | 330 | Protein_152 | recombinase family protein | - |
PML74_RS13605 (PML74_13605) | 148195..148731 | + | 537 | Protein_153 | IS6 family transposase IS1216E | Transposase |
PML74_RS13610 (PML74_13610) | 148814..150109 | - | 1296 | WP_002297185.1 | ISL3 family transposase ISEfa5 | Transposase |
PML74_RS13615 (PML74_13615) | 150245..150397 | + | 153 | Protein_155 | IS6 family transposase | - |
PML74_RS13620 (PML74_13620) | 150431..150604 | - | 174 | WP_229214455.1 | hypothetical protein | - |
PML74_RS13625 (PML74_13625) | 150616..151353 | - | 738 | WP_002331331.1 | S8 family serine peptidase | - |
PML74_RS13630 (PML74_13630) | 151613..152161 | - | 549 | WP_002292681.1 | hypothetical protein | - |
PML74_RS13635 (PML74_13635) | 152162..153019 | - | 858 | WP_002292680.1 | ParA family protein | - |
PML74_RS13640 (PML74_13640) | 153304..153591 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
PML74_RS13645 (PML74_13645) | 153581..153910 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
PML74_RS13650 (PML74_13650) | 153987..154259 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
PML74_RS13655 (PML74_13655) | 154259..154522 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
PML74_RS13660 (PML74_13660) | 154628..155551 | - | 924 | WP_002331332.1 | hypothetical protein | - |
PML74_RS13665 (PML74_13665) | 156110..156427 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
PML74_RS13670 (PML74_13670) | 156428..156682 | - | 255 | WP_002297424.1 | hypothetical protein | - |
PML74_RS13675 (PML74_13675) | 156942..157082 | - | 141 | WP_002290398.1 | hypothetical protein | - |
PML74_RS13680 (PML74_13680) | 157720..157806 | - | 87 | Protein_168 | single-stranded DNA-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
---|