MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 134360 bp
Accession: NZ_CP116537 Location: 1..134360 Organism: Enterococcus faecium strain K162-1 Replicon: plasmid pK162-1-A
Accession: NZ_CP116537 Location: 1..134360 Organism: Enterococcus faecium strain K162-1 Replicon: plasmid pK162-1-A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PML70_RS13005 (PML70_13005) | 1..1041 | + | 1041 | WP_272016962.1 | replication initiator protein A | - |
| PML70_RS13010 (PML70_13010) | 1881..2213 | + | 333 | WP_272016964.1 | type IV conjugative transfer system protein TraE | - |
| PML70_RS13015 (PML70_13015) | 2832..3173 | + | 342 | WP_002314399.1 | DUF5406 family protein | - |
| PML70_RS13020 (PML70_13020) | 3192..3482 | + | 291 | WP_002311523.1 | hypothetical protein | - |
| PML70_RS13025 (PML70_13025) | 3674..3907 | + | 234 | WP_002311524.1 | hypothetical protein | - |
| PML70_RS13030 (PML70_13030) | 3974..4213 | + | 240 | WP_272016966.1 | hypothetical protein | - |
| PML70_RS13035 (PML70_13035) | 4299..4970 | + | 672 | WP_002311526.1 | class A sortase | - |
| PML70_RS13040 (PML70_13040) | 5023..6999 | + | 1977 | WP_131773725.1 | SpaA isopeptide-forming pilin-related protein | - |
| PML70_RS13045 (PML70_13045) | 7012..7767 | + | 756 | WP_272016968.1 | hypothetical protein | VF |
| PML70_RS13050 (PML70_13050) | 7764..8591 | + | 828 | WP_047936599.1 | pilin N-terminal domain-containing protein | - |
| PML70_RS13055 (PML70_13055) | 8601..8849 | + | 249 | WP_002311534.1 | hypothetical protein | - |
| PML70_RS13060 (PML70_13060) | 8892..10991 | + | 2100 | WP_251843994.1 | isopeptide-forming domain-containing fimbrial protein | - |
| PML70_RS13065 (PML70_13065) | 11027..13078 | - | 2052 | WP_272016970.1 | hypothetical protein | VF |
| PML70_RS13070 (PML70_13070) | 13198..13407 | - | 210 | WP_002311538.1 | hypothetical protein | - |
| PML70_RS13075 (PML70_13075) | 13595..14062 | + | 468 | WP_272016971.1 | hypothetical protein | - |
| PML70_RS13080 (PML70_13080) | 14059..14301 | + | 243 | WP_002305229.1 | DUF5415 family protein | - |
| PML70_RS13085 (PML70_13085) | 14319..14621 | + | 303 | WP_002314409.1 | hypothetical protein | - |
| PML70_RS13090 (PML70_13090) | 14691..16754 | + | 2064 | WP_272016973.1 | hypothetical protein | - |
| PML70_RS13095 (PML70_13095) | 16754..19366 | + | 2613 | WP_272016975.1 | type IV secretory system conjugative DNA transfer family protein | - |
| PML70_RS13100 (PML70_13100) | 19363..21759 | + | 2397 | WP_272016976.1 | hypothetical protein | - |
| PML70_RS13105 (PML70_13105) | 21811..22143 | + | 333 | WP_002295656.1 | hypothetical protein | - |
| PML70_RS13110 (PML70_13110) | 22144..22737 | + | 594 | WP_002307538.1 | hypothetical protein | - |
| PML70_RS13115 (PML70_13115) | 22797..23045 | + | 249 | WP_002332281.1 | hypothetical protein | - |
| PML70_RS13120 (PML70_13120) | 23326..23976 | + | 651 | WP_010728919.1 | hypothetical protein | - |
| PML70_RS13125 (PML70_13125) | 24100..24273 | + | 174 | WP_002314417.1 | hypothetical protein | - |
| PML70_RS13130 (PML70_13130) | 24273..26297 | + | 2025 | WP_002314418.1 | ATPase | - |
| PML70_RS13135 (PML70_13135) | 26297..27502 | + | 1206 | WP_272016978.1 | glucosaminidase domain-containing protein | - |
| PML70_RS13140 (PML70_13140) | 27518..28162 | + | 645 | WP_086310173.1 | hypothetical protein | - |
| PML70_RS13145 (PML70_13145) | 28173..28979 | + | 807 | WP_002314421.1 | hypothetical protein | - |
| PML70_RS13150 (PML70_13150) | 29002..29232 | + | 231 | WP_002295643.1 | hypothetical protein | - |
| PML70_RS13155 (PML70_13155) | 29250..29393 | + | 144 | WP_002293512.1 | hypothetical protein | - |
| PML70_RS13160 (PML70_13160) | 29779..30054 | + | 276 | WP_002325546.1 | hypothetical protein | - |
| PML70_RS13165 (PML70_13165) | 30096..30518 | + | 423 | WP_002302844.1 | hypothetical protein | - |
| PML70_RS13170 (PML70_13170) | 30538..32130 | + | 1593 | WP_033582043.1 | hypothetical protein | Relaxase |
| PML70_RS13175 (PML70_13175) | 32151..32486 | + | 336 | WP_002310991.1 | hypothetical protein | - |
| PML70_RS13180 (PML70_13180) | 32632..32826 | + | 195 | WP_002302840.1 | hypothetical protein | - |
| PML70_RS13185 (PML70_13185) | 32839..35211 | + | 2373 | WP_086272989.1 | hypothetical protein | - |
| PML70_RS13190 (PML70_13190) | 35272..36732 | + | 1461 | WP_010728922.1 | toprim domain-containing protein | - |
| PML70_RS13195 (PML70_13195) | 36743..38947 | + | 2205 | WP_272016988.1 | type IA DNA topoisomerase | - |
| PML70_RS13200 (PML70_13200) | 38963..39112 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| PML70_RS13205 (PML70_13205) | 39193..39789 | + | 597 | WP_002293530.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| PML70_RS13210 (PML70_13210) | 39802..40701 | + | 900 | WP_002325540.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| PML70_RS13215 (PML70_13215) | 40704..41189 | + | 486 | WP_272016980.1 | single-stranded DNA-binding protein | - |
| PML70_RS13220 (PML70_13220) | 41555..41815 | + | 261 | WP_002325538.1 | hypothetical protein | - |
| PML70_RS13225 (PML70_13225) | 42260..42466 | + | 207 | WP_002325537.1 | hypothetical protein | - |
| PML70_RS13230 (PML70_13230) | 42466..42717 | + | 252 | WP_002320549.1 | hypothetical protein | - |
| PML70_RS13235 (PML70_13235) | 42733..43170 | + | 438 | WP_010728924.1 | hypothetical protein | - |
| PML70_RS13240 (PML70_13240) | 43163..43870 | + | 708 | WP_002325535.1 | hypothetical protein | - |
| PML70_RS13245 (PML70_13245) | 44251..44430 | + | 180 | WP_002325533.1 | hypothetical protein | - |
| PML70_RS13250 (PML70_13250) | 44886..45566 | - | 681 | WP_272016982.1 | IS6 family transposase IS1216E | Transposase |
| PML70_RS13255 (PML70_13255) | 45641..46539 | + | 899 | Protein_50 | IS3 family transposase ISKpn38 | Transposase |
| PML70_RS13260 (PML70_13260) | 46774..47646 | - | 873 | WP_272016990.1 | ROK family protein | - |
| PML70_RS13265 (PML70_13265) | 47910..49856 | - | 1947 | WP_002341364.1 | sucrose-specific PTS transporter subunit IIBC | - |
| PML70_RS13270 (PML70_13270) | 50041..51480 | + | 1440 | WP_002332299.1 | sucrose-6-phosphate hydrolase | - |
| PML70_RS13275 (PML70_13275) | 51482..52444 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| PML70_RS13280 (PML70_13280) | 52614..53666 | - | 1053 | WP_226816283.1 | IS3 family transposase ISEfa10 | Transposase |
| PML70_RS13285 (PML70_13285) | 53554..54039 | - | 486 | WP_272016984.1 | IS3 family transposase ISEfa10 | Transposase |
| PML70_RS13290 (PML70_13290) | 54156..54311 | - | 156 | Protein_57 | transposase | - |
| PML70_RS13295 (PML70_13295) | 54575..54889 | - | 315 | Protein_58 | transposase | - |
| PML70_RS13300 (PML70_13300) | 54962..55198 | + | 237 | WP_002341366.1 | hypothetical protein | - |
| PML70_RS13305 (PML70_13305) | 55417..55608 | + | 192 | WP_174131346.1 | hypothetical protein | - |
| PML70_RS13310 (PML70_13310) | 56036..57475 | + | 1440 | WP_086294247.1 | primase C-terminal domain-containing protein | - |
| PML70_RS13315 (PML70_13315) | 57519..57713 | + | 195 | WP_002311030.1 | hypothetical protein | - |
| PML70_RS13320 (PML70_13320) | 57727..57867 | + | 141 | WP_002316998.1 | hypothetical protein | - |
| PML70_RS13325 (PML70_13325) | 57881..59686 | + | 1806 | WP_272016986.1 | type IA DNA topoisomerase | - |
| PML70_RS13330 (PML70_13330) | 60243..60431 | + | 189 | WP_002338065.1 | hypothetical protein | - |
| PML70_RS13335 (PML70_13335) | 61156..61578 | + | 423 | WP_002307506.1 | cupin domain-containing protein | - |
| PML70_RS13340 (PML70_13340) | 61662..62315 | + | 654 | WP_002307505.1 | putative iron export ATP-binding protein FetA | VF |
| PML70_RS13345 (PML70_13345) | 62312..63076 | + | 765 | WP_002311027.1 | iron export ABC transporter permease subunit FetB | - |
| PML70_RS13350 (PML70_13350) | 63487..63723 | + | 237 | WP_002356094.1 | DUF302 domain-containing protein | - |
| PML70_RS13355 (PML70_13355) | 63750..63933 | - | 184 | Protein_70 | recombinase family protein | - |
| PML70_RS13360 (PML70_13360) | 64193..64792 | + | 600 | WP_002301839.1 | Tyrosine recombinase XerC | VF |
| PML70_RS13365 (PML70_13365) | 64856..65755 | + | 900 | WP_002311023.1 | AbiH family protein | - |
| PML70_RS13370 (PML70_13370) | 66525..67400 | + | 876 | WP_174131347.1 | hypothetical protein | - |
| PML70_RS13375 (PML70_13375) | 67419..67886 | + | 468 | WP_174131348.1 | hypothetical protein | - |
| PML70_RS13380 (PML70_13380) | 68130..69455 | + | 1326 | WP_139969774.1 | Y-family DNA polymerase | - |
| PML70_RS13385 (PML70_13385) | 69448..69798 | + | 351 | WP_002290348.1 | hypothetical protein | - |
| PML70_RS13390 (PML70_13390) | 69939..70448 | + | 510 | WP_002295345.1 | hypothetical protein | - |
| PML70_RS13395 (PML70_13395) | 70899..71306 | - | 408 | WP_002329899.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| PML70_RS13400 (PML70_13400) | 71303..71536 | - | 234 | WP_002297441.1 | addiction module antitoxin | - |
| PML70_RS13405 (PML70_13405) | 71870..72955 | + | 1086 | WP_002290352.1 | tyrosine recombinase XerS | - |
| PML70_RS13410 (PML70_13410) | 73239..73904 | - | 666 | WP_002324528.1 | site-specific integrase | - |
| PML70_RS13415 (PML70_13415) | 74058..74207 | - | 150 | WP_002290356.1 | hypothetical protein | - |
| PML70_RS13420 (PML70_13420) | 74200..74409 | - | 210 | WP_002290357.1 | DUF3173 domain-containing protein | - |
| PML70_RS13425 (PML70_13425) | 74731..75231 | - | 501 | WP_230307293.1 | IS4 family transposase IS641 | Transposase |
| PML70_RS13430 (PML70_13430) | 75244..75837 | - | 594 | WP_230307292.1 | IS4 family transposase IS641 | Transposase |
| PML70_RS13435 (PML70_13435) | 75914..77374 | - | 1461 | WP_105222592.1 | sucrose phosphorylase | - |
| PML70_RS13440 (PML70_13440) | 77371..78591 | - | 1221 | WP_272016950.1 | alpha-amylase family glycosyl hydrolase | - |
| PML70_RS13445 (PML70_13445) | 78652..80835 | - | 2184 | WP_002324534.1 | alpha-galactosidase | - |
| PML70_RS13450 (PML70_13450) | 80875..81705 | - | 831 | WP_002290368.1 | carbohydrate ABC transporter permease | - |
| PML70_RS13455 (PML70_13455) | 81717..82589 | - | 873 | WP_002290370.1 | sugar ABC transporter permease | - |
| PML70_RS13460 (PML70_13460) | 82599..83858 | - | 1260 | WP_002290371.1 | extracellular solute-binding protein | - |
| PML70_RS13465 (PML70_13465) | 84007..85317 | - | 1311 | WP_113833198.1 | alpha-glucosidase/alpha-galactosidase | - |
| PML70_RS13470 (PML70_13470) | 85349..86173 | - | 825 | WP_047929206.1 | carbohydrate ABC transporter permease | - |
| PML70_RS13475 (PML70_13475) | 86189..87085 | - | 897 | Protein_94 | sugar ABC transporter permease | - |
| PML70_RS13480 (PML70_13480) | 87168..88433 | - | 1266 | WP_139969772.1 | extracellular solute-binding protein | - |
| PML70_RS13485 (PML70_13485) | 88571..89596 | - | 1026 | WP_002290378.1 | LacI family DNA-binding transcriptional regulator | - |
| PML70_RS13490 (PML70_13490) | 89841..91112 | - | 1272 | WP_086272983.1 | substrate-binding domain-containing protein | - |
| PML70_RS13495 (PML70_13495) | 91396..92343 | - | 948 | WP_086272982.1 | VOC family protein | - |
| PML70_RS13500 (PML70_13500) | 92391..92828 | + | 438 | WP_229033435.1 | IS91 family transposase ISCARN110 | Transposase |
| PML70_RS13505 (PML70_13505) | 93001..93555 | - | 555 | WP_002290383.1 | tyrosine-type recombinase/integrase | - |
| PML70_RS13510 (PML70_13510) | 95212..95891 | - | 680 | Protein_101 | IS6 family transposase IS1297 | Transposase |
| PML70_RS13515 (PML70_13515) | 96111..96452 | + | 342 | WP_230307300.1 | ISL3 family transposase IS1476 | Transposase |
| PML70_RS13520 (PML70_13520) | 96412..96882 | + | 471 | WP_032495001.1 | ISL3 family transposase IS1476 | Transposase |
| PML70_RS13525 (PML70_13525) | 97080..97676 | - | 597 | WP_002351732.1 | YdhK family protein | - |
| PML70_RS13530 (PML70_13530) | 97697..97903 | - | 207 | WP_002307659.1 | hypothetical protein | - |
| PML70_RS13535 (PML70_13535) | 97918..98538 | - | 621 | Protein_106 | Sensor histidine kinase ResE | VF |
| PML70_RS13540 (PML70_13540) | 98513..98782 | + | 270 | WP_033607283.1 | hypothetical protein | - |
| PML70_RS13545 (PML70_13545) | 99104..99928 | - | 825 | WP_002332312.1 | endonuclease/exonuclease/phosphatase family protein | - |
| PML70_RS13550 (PML70_13550) | 100141..102303 | - | 2163 | WP_272016952.1 | PTS transporter subunit IIBC | - |
| PML70_RS13555 (PML70_13555) | 102584..104878 | + | 2295 | WP_174131342.1 | glycoside hydrolase family 65 protein | - |
| PML70_RS13560 (PML70_13560) | 104871..105536 | + | 666 | WP_002316716.1 | beta-phosphoglucomutase | - |
| PML70_RS13565 (PML70_13565) | 105529..106563 | + | 1035 | WP_002316717.1 | aldose epimerase family protein | - |
| PML70_RS13570 (PML70_13570) | 106632..107651 | + | 1020 | WP_272016954.1 | Catabolite control protein A | VF |
| PML70_RS13575 (PML70_13575) | 108111..108574 | - | 464 | Protein_114 | hydantoinase/oxoprolinase N-terminal domain-containing protein | - |
| PML70_RS13585 (PML70_13585) | 109644..110537 | + | 894 | WP_002316719.1 | neutral zinc metallopeptidase | - |
| PML70_RS13595 (PML70_13595) | 111077..112362 | + | 1286 | Protein_117 | cytochrome P450 | - |
| PML70_RS13600 (PML70_13600) | 112434..114059 | - | 1626 | WP_002336223.1 | peptide ABC transporter substrate-binding protein | - |
| PML70_RS13605 (PML70_13605) | 114551..115000 | + | 450 | WP_002331389.1 | DIP1984 family protein | - |
| PML70_RS13610 (PML70_13610) | 115372..115896 | - | 525 | WP_002316725.1 | IS630 family transposase ISBs2 | Transposase |
| PML70_RS13615 (PML70_13615) | 115915..117258 | - | 1344 | WP_002332322.1 | PFL family protein | - |
| PML70_RS13620 (PML70_13620) | 117273..117539 | - | 267 | WP_002290085.1 | ACT domain-containing protein | - |
| PML70_RS13625 (PML70_13625) | 117642..118310 | - | 669 | WP_002316727.1 | 2,3-diphosphoglycerate-dependent phosphoglycerate mutase | - |
| PML70_RS13630 (PML70_13630) | 118386..119515 | + | 1130 | WP_119657924.1 | IS3 family transposase ISBce13 | Transposase |
| PML70_RS13635 (PML70_13635) | 119665..120228 | - | 564 | WP_002316729.1 | hypothetical protein | - |
| PML70_RS13640 (PML70_13640) | 120488..121036 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| PML70_RS13645 (PML70_13645) | 121037..121894 | - | 858 | WP_002292680.1 | ParA family protein | - |
| PML70_RS13650 (PML70_13650) | 122180..122467 | - | 288 | WP_130624911.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PML70_RS13655 (PML70_13655) | 122457..122786 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| PML70_RS13660 (PML70_13660) | 122863..123135 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| PML70_RS13665 (PML70_13665) | 123135..123398 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| PML70_RS13670 (PML70_13670) | 123632..124540 | + | 909 | Protein_132 | IS982 family transposase ISEfm1 | Transposase |
| PML70_RS13675 (PML70_13675) | 124543..125718 | - | 1176 | WP_002336205.1 | MFS transporter | - |
| PML70_RS13680 (PML70_13680) | 125721..127970 | - | 2250 | WP_272016958.1 | alpha-galactosidase | - |
| PML70_RS13685 (PML70_13685) | 128067..128921 | - | 855 | WP_010728908.1 | AraC family transcriptional regulator | - |
| PML70_RS13690 (PML70_13690) | 129003..129911 | - | 909 | WP_002332990.1 | IS982 family transposase ISEfm1 | Transposase |
| PML70_RS13695 (PML70_13695) | 130005..130940 | - | 936 | WP_272016960.1 | hypothetical protein | - |
| PML70_RS13700 (PML70_13700) | 131499..131816 | - | 318 | WP_002341346.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PML70_RS13705 (PML70_13705) | 131817..132071 | - | 255 | WP_002290397.1 | AbrB family transcriptional regulator | - |
| PML70_RS13710 (PML70_13710) | 132331..132471 | - | 141 | WP_002290398.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|