MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 122895 bp
Accession: NZ_CP116518 Location: 1..122895 Organism: Enterococcus faecium strain R39-1 Replicon: plasmid pR39-1-A
Accession: NZ_CP116518 Location: 1..122895 Organism: Enterococcus faecium strain R39-1 Replicon: plasmid pR39-1-A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PML88_RS12245 (PML88_12245) | 1..1041 | + | 1041 | WP_002323095.1 | replication initiator protein A | - |
| PML88_RS12250 (PML88_12250) | 1881..2213 | + | 333 | WP_002322486.1 | type IV conjugative transfer system protein TraE | - |
| PML88_RS12255 (PML88_12255) | 2832..3173 | + | 342 | Protein_2 | DUF5406 family protein | - |
| PML88_RS12260 (PML88_12260) | 3192..3314 | + | 123 | WP_002293478.1 | hypothetical protein | - |
| PML88_RS12265 (PML88_12265) | 3340..3579 | + | 240 | WP_002347362.1 | hypothetical protein | - |
| PML88_RS12270 (PML88_12270) | 3645..3884 | + | 240 | WP_002322851.1 | hypothetical protein | - |
| PML88_RS12275 (PML88_12275) | 4239..4888 | + | 650 | Protein_6 | EpaQ family protein | - |
| PML88_RS12280 (PML88_12280) | 4970..5641 | + | 672 | WP_002347361.1 | class A sortase | - |
| PML88_RS12285 (PML88_12285) | 5694..7670 | + | 1977 | WP_016631144.1 | SpaA isopeptide-forming pilin-related protein | - |
| PML88_RS12290 (PML88_12290) | 7685..8437 | + | 753 | WP_002293487.1 | hypothetical protein | VF |
| PML88_RS12295 (PML88_12295) | 8453..9208 | + | 756 | WP_002320589.1 | pilin N-terminal domain-containing protein | - |
| PML88_RS12300 (PML88_12300) | 9221..9481 | + | 261 | WP_002314405.1 | hypothetical protein | - |
| PML88_RS12305 (PML88_12305) | 9478..11568 | + | 2091 | WP_016631142.1 | isopeptide-forming domain-containing fimbrial protein | - |
| PML88_RS12310 (PML88_12310) | 11595..12059 | + | 465 | WP_002310966.1 | hypothetical protein | - |
| PML88_RS12315 (PML88_12315) | 12056..12298 | + | 243 | WP_002305229.1 | DUF5415 family protein | - |
| PML88_RS12320 (PML88_12320) | 12316..12618 | + | 303 | WP_002295662.1 | hypothetical protein | - |
| PML88_RS12325 (PML88_12325) | 12688..14763 | + | 2076 | WP_016631141.1 | hypothetical protein | - |
| PML88_RS12330 (PML88_12330) | 14763..17372 | + | 2610 | WP_002331344.1 | type IV secretory system conjugative DNA transfer family protein | - |
| PML88_RS12335 (PML88_12335) | 17369..19747 | + | 2379 | WP_010706253.1 | hypothetical protein | - |
| PML88_RS12340 (PML88_12340) | 19799..20131 | + | 333 | WP_002340493.1 | hypothetical protein | - |
| PML88_RS12345 (PML88_12345) | 20132..20725 | + | 594 | WP_002340492.1 | hypothetical protein | - |
| PML88_RS12350 (PML88_12350) | 20888..22912 | + | 2025 | WP_002340490.1 | hypothetical protein | - |
| PML88_RS12355 (PML88_12355) | 22912..24117 | + | 1206 | WP_002323679.1 | glucosaminidase domain-containing protein | - |
| PML88_RS12360 (PML88_12360) | 24133..24777 | + | 645 | WP_002321287.1 | hypothetical protein | - |
| PML88_RS12365 (PML88_12365) | 24788..25594 | + | 807 | WP_002323678.1 | hypothetical protein | - |
| PML88_RS12370 (PML88_12370) | 25617..25847 | + | 231 | WP_002323677.1 | hypothetical protein | - |
| PML88_RS12375 (PML88_12375) | 26136..27298 | + | 1163 | WP_086956687.1 | IS3 family transposase IS1485 | Transposase |
| PML88_RS12380 (PML88_12380) | 27432..28364 | + | 933 | WP_002338120.1 | DUF4199 domain-containing protein | - |
| PML88_RS12385 (PML88_12385) | 28366..28938 | + | 573 | WP_002338121.1 | hypothetical protein | - |
| PML88_RS12390 (PML88_12390) | 28832..29101 | + | 270 | WP_025477911.1 | hypothetical protein | - |
| PML88_RS12395 (PML88_12395) | 29323..29619 | + | 297 | WP_002293513.1 | hypothetical protein | - |
| PML88_RS12400 (PML88_12400) | 29621..30043 | + | 423 | WP_010726517.1 | hypothetical protein | - |
| PML88_RS12405 (PML88_12405) | 30062..31654 | + | 1593 | WP_033611853.1 | hypothetical protein | Relaxase |
| PML88_RS12410 (PML88_12410) | 31666..32001 | + | 336 | WP_002310991.1 | hypothetical protein | - |
| PML88_RS12415 (PML88_12415) | 32142..32336 | + | 195 | WP_010726515.1 | hypothetical protein | - |
| PML88_RS12420 (PML88_12420) | 32349..34720 | + | 2372 | Protein_35 | ArdC-like ssDNA-binding domain-containing protein | - |
| PML88_RS12425 (PML88_12425) | 34781..36250 | + | 1470 | WP_010726513.1 | toprim domain-containing protein | - |
| PML88_RS12430 (PML88_12430) | 36261..38465 | + | 2205 | WP_010726512.1 | type IA DNA topoisomerase | - |
| PML88_RS12435 (PML88_12435) | 38481..38630 | + | 150 | WP_002359413.1 | hypothetical protein | - |
| PML88_RS12440 (PML88_12440) | 38710..39306 | + | 597 | WP_002293530.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| PML88_RS12445 (PML88_12445) | 39319..40218 | + | 900 | WP_010726511.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| PML88_RS12450 (PML88_12450) | 40221..40706 | + | 486 | WP_010726510.1 | single-stranded DNA-binding protein | - |
| PML88_RS12455 (PML88_12455) | 40728..40985 | + | 258 | WP_010726509.1 | hypothetical protein | - |
| PML88_RS12460 (PML88_12460) | 41144..41288 | - | 145 | Protein_43 | putative holin-like toxin | - |
| PML88_RS12465 (PML88_12465) | 41420..41680 | + | 261 | WP_070828439.1 | hypothetical protein | - |
| PML88_RS12470 (PML88_12470) | 42129..42335 | + | 207 | WP_002296239.1 | hypothetical protein | - |
| PML88_RS12475 (PML88_12475) | 42335..42586 | + | 252 | WP_002320549.1 | hypothetical protein | - |
| PML88_RS12480 (PML88_12480) | 42602..43039 | + | 438 | WP_002320550.1 | hypothetical protein | - |
| PML88_RS12485 (PML88_12485) | 43032..43739 | + | 708 | Protein_48 | hypothetical protein | - |
| PML88_RS12490 (PML88_12490) | 43904..44104 | + | 201 | WP_002352830.1 | hypothetical protein | - |
| PML88_RS12495 (PML88_12495) | 44120..44299 | + | 180 | Protein_50 | hypothetical protein | - |
| PML88_RS12500 (PML88_12500) | 44358..45038 | + | 681 | WP_005874952.1 | hypothetical protein | - |
| PML88_RS12505 (PML88_12505) | 45366..46046 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| PML88_RS12510 (PML88_12510) | 46100..47305 | - | 1206 | WP_002285820.1 | ISL3 family transposase ISEfa11 | Transposase |
| PML88_RS12515 (PML88_12515) | 47484..48245 | - | 762 | Protein_54 | ISL3 family transposase IS1476 | Transposase |
| PML88_RS12520 (PML88_12520) | 48300..49814 | + | 1515 | WP_010726506.1 | IS3 family transposase ISKpn38 | Transposase |
| PML88_RS12525 (PML88_12525) | 50118..50942 | - | 825 | WP_010726505.1 | MBL fold metallo-hydrolase | - |
| PML88_RS12530 (PML88_12530) | 51285..51701 | + | 417 | WP_002343823.1 | hypothetical protein | - |
| PML88_RS12535 (PML88_12535) | 51698..52168 | + | 471 | WP_002298375.1 | PTS sugar transporter subunit IIB | - |
| PML88_RS12540 (PML88_12540) | 52182..52955 | + | 774 | WP_002298373.1 | PTS sugar transporter subunit IIC | - |
| PML88_RS12545 (PML88_12545) | 52969..53781 | + | 813 | WP_002298371.1 | PTS system mannose/fructose/sorbose family transporter subunit IID | - |
| PML88_RS12550 (PML88_12550) | 53835..54800 | + | 966 | WP_002347643.1 | SIS domain-containing protein | - |
| PML88_RS12555 (PML88_12555) | 54937..57660 | + | 2724 | WP_002347642.1 | Transcriptional regulatory protein DagR | VF |
| PML88_RS12560 (PML88_12560) | 57673..58305 | + | 633 | WP_002298365.1 | HAD family phosphatase | - |
| PML88_RS12565 (PML88_12565) | 59210..59425 | - | 216 | WP_010726504.1 | hypothetical protein | - |
| PML88_RS12570 (PML88_12570) | 59949..61139 | + | 1191 | Protein_65 | IS256 family transposase ISEf1 | Transposase |
| PML88_RS12575 (PML88_12575) | 61290..62615 | + | 1326 | WP_010726502.1 | Y-family DNA polymerase | - |
| PML88_RS12580 (PML88_12580) | 62608..62958 | + | 351 | WP_002290348.1 | hypothetical protein | - |
| PML88_RS12590 (PML88_12590) | 64468..64977 | + | 510 | WP_002295345.1 | hypothetical protein | - |
| PML88_RS12595 (PML88_12595) | 65428..65835 | - | 408 | WP_002297442.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| PML88_RS12600 (PML88_12600) | 65832..66065 | - | 234 | WP_002297441.1 | addiction module antitoxin | - |
| PML88_RS12605 (PML88_12605) | 66398..67483 | + | 1086 | WP_002297440.1 | tyrosine recombinase XerS | - |
| PML88_RS12610 (PML88_12610) | 67769..68947 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| PML88_RS12615 (PML88_12615) | 69181..70071 | + | 891 | WP_002297439.1 | hypothetical protein | - |
| PML88_RS12620 (PML88_12620) | 70508..71062 | - | 555 | WP_002295761.1 | tyrosine-type recombinase/integrase | - |
| PML88_RS12625 (PML88_12625) | 71805..72347 | + | 543 | Protein_76 | PHP domain-containing protein | - |
| PML88_RS12630 (PML88_12630) | 72398..73210 | - | 813 | WP_002322679.1 | AAA family ATPase | - |
| PML88_RS12635 (PML88_12635) | 73203..74639 | - | 1437 | WP_002322678.1 | Mu transposase C-terminal domain-containing protein | - |
| PML88_RS12640 (PML88_12640) | 74611..75204 | - | 594 | WP_002322677.1 | Tn3 family transposase TnBth3 | Transposase |
| PML88_RS12645 (PML88_12645) | 75436..75666 | + | 231 | WP_002322676.1 | hypothetical protein | Antitoxin Detail |
| PML88_RS12650 (PML88_12650) | 75666..76007 | + | 342 | WP_002322675.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| PML88_RS12655 (PML88_12655) | 76221..77723 | - | 1503 | WP_002322674.1 | xylulokinase | - |
| PML88_RS12660 (PML88_12660) | 77796..78848 | - | 1053 | WP_002323515.1 | sugar ABC transporter substrate-binding protein | - |
| PML88_RS12665 (PML88_12665) | 78901..79869 | - | 969 | WP_002322672.1 | ABC transporter permease | - |
| PML88_RS12670 (PML88_12670) | 79934..81442 | - | 1509 | WP_002322671.1 | sugar ABC transporter ATP-binding protein | - |
| PML88_RS12675 (PML88_12675) | 81492..83102 | - | 1611 | WP_002322670.1 | glycoside hydrolase family 43 protein | - |
| PML88_RS12680 (PML88_12680) | 83202..84509 | - | 1308 | WP_002322669.1 | xylose isomerase | - |
| PML88_RS12685 (PML88_12685) | 84796..85950 | + | 1155 | WP_002323041.1 | ROK family transcriptional regulator | - |
| PML88_RS12690 (PML88_12690) | 86041..86367 | - | 327 | Protein_89 | DDE-type integrase/transposase/recombinase | - |
| PML88_RS12695 (PML88_12695) | 86521..86721 | + | 201 | Protein_90 | hypothetical protein | - |
| PML88_RS12700 (PML88_12700) | 86718..87215 | - | 498 | WP_002316138.1 | Spermidine/spermine N(1)-acetyltransferase | VF |
| PML88_RS12705 (PML88_12705) | 87271..88179 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| PML88_RS12710 (PML88_12710) | 88940..90127 | + | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| PML88_RS12715 (PML88_12715) | 90460..91140 | - | 681 | WP_085803942.1 | IS6 family transposase ISS1W | Transposase |
| PML88_RS12720 (PML88_12720) | 91338..93242 | - | 1905 | WP_002322690.1 | heavy metal translocating P-type ATPase | - |
| PML88_RS12725 (PML88_12725) | 93440..93673 | - | 234 | WP_002301447.1 | heavy-metal-associated domain-containing protein | - |
| PML88_RS12730 (PML88_12730) | 93820..94674 | - | 855 | WP_002322689.1 | prolipoprotein diacylglyceryl transferase | - |
| PML88_RS12735 (PML88_12735) | 94659..94997 | - | 339 | WP_002300938.1 | hypothetical protein | - |
| PML88_RS12740 (PML88_12740) | 95225..95929 | - | 705 | WP_002292156.1 | Crp/Fnr family transcriptional regulator | - |
| PML88_RS12745 (PML88_12745) | 96074..96646 | - | 573 | WP_002292150.1 | DNA protection during starvation protein | VF |
| PML88_RS12750 (PML88_12750) | 97057..97473 | - | 417 | Protein_101 | IS982 family transposase ISEfm1 | Transposase |
| PML88_RS12755 (PML88_12755) | 97545..98837 | + | 1293 | WP_002298232.1 | ISL3 family transposase IS1251 | Transposase |
| PML88_RS12760 (PML88_12760) | 99049..99891 | - | 843 | WP_002289586.1 | PRD domain-containing protein | - |
| PML88_RS12765 (PML88_12765) | 99928..101394 | - | 1467 | WP_002289584.1 | glycoside hydrolase family 1 protein | - |
| PML88_RS12770 (PML88_12770) | 101450..103294 | - | 1845 | WP_002298230.1 | beta-glucoside-specific PTS transporter subunit IIABC | - |
| PML88_RS12775 (PML88_12775) | 103896..104846 | + | 951 | WP_002300609.1 | Transcriptional regulatory protein DagR | VF |
| PML88_RS12780 (PML88_12780) | 104924..105019 | - | 96 | Protein_107 | S8 family serine peptidase | - |
| PML88_RS12785 (PML88_12785) | 105063..105524 | - | 462 | WP_002298224.1 | hypothetical protein | - |
| PML88_RS12790 (PML88_12790) | 105784..106332 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| PML88_RS12795 (PML88_12795) | 106333..107190 | - | 858 | WP_002292680.1 | ParA family protein | - |
| PML88_RS12800 (PML88_12800) | 107476..107763 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PML88_RS12805 (PML88_12805) | 107753..108082 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| PML88_RS12810 (PML88_12810) | 108159..108356 | - | 198 | WP_079504111.1 | Txe/YoeB family addiction module toxin | - |
| PML88_RS12815 (PML88_12815) | 108357..109037 | - | 681 | Protein_114 | IS6 family transposase IS1216V | Transposase |
| PML88_RS12820 (PML88_12820) | 109091..109258 | - | 168 | WP_002322961.1 | hypothetical protein | - |
| PML88_RS12825 (PML88_12825) | 109291..110691 | - | 1401 | WP_002298077.1 | YfcC family protein | - |
| PML88_RS12830 (PML88_12830) | 110739..111068 | - | 330 | Protein_117 | amidohydrolase family protein | - |
| PML88_RS12835 (PML88_12835) | 111226..112413 | + | 1188 | WP_002296840.1 | IS256 family transposase IS16 | Transposase |
| PML88_RS12840 (PML88_12840) | 112471..113712 | - | 1242 | WP_077149156.1 | amidohydrolase family protein | - |
| PML88_RS12845 (PML88_12845) | 113748..114458 | - | 711 | WP_002288618.1 | GntR family transcriptional regulator | - |
| PML88_RS12850 (PML88_12850) | 114526..115341 | - | 816 | WP_002288615.1 | fructoselysine 6-kinase | - |
| PML88_RS12855 (PML88_12855) | 115352..116320 | - | 969 | WP_002288613.1 | SIS domain-containing protein | - |
| PML88_RS12860 (PML88_12860) | 117130..118083 | + | 954 | WP_060799464.1 | IS30 family transposase IS1252 | Transposase |
| PML88_RS12865 (PML88_12865) | 118792..119109 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PML88_RS12870 (PML88_12870) | 119110..119364 | - | 255 | WP_002290397.1 | AbrB family transcriptional regulator | - |
| PML88_RS12875 (PML88_12875) | 119624..119764 | - | 141 | WP_002290398.1 | hypothetical protein | - |
| PML88_RS12880 (PML88_12880) | 120298..120384 | - | 87 | Protein_127 | single-stranded DNA-binding protein | - |
| PML88_RS12885 (PML88_12885) | 120840..122018 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|