MGE detailed information
MGE type: Conjugative plasmid MGE length: 93520 bp
Accession: NZ_CP116177 Location: 1..93520 Organism: Escherichia coli strain DETEC-E601 Replicon: plasmid pDETEC61
Accession: NZ_CP116177 Location: 1..93520 Organism: Escherichia coli strain DETEC-E601 Replicon: plasmid pDETEC61
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIC02_RS23740 (101) | 101..349 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| PIC02_RS23745 (594) | 594..668 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| PIC02_RS23750 (661) | 661..1518 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| PIC02_RS23755 (2457) | 2457..2615 | + | 159 | WP_047667301.1 | membrane protein | - |
| PIC02_RS23760 (2779) | 2779..3978 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| PIC02_RS23765 (3988) | 3988..4176 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| PIC02_RS23770 (4296) | 4296..5726 | + | 1431 | Protein_6 | IS4 family transposase IS50R | Transposase |
| PIC02_RS23775 (5755) | 5755..6549 | + | 795 | WP_000572405.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| PIC02_RS23780 (6570) | 6570..6806 | + | 237 | Protein_8 | hypothetical protein | - |
| PIC02_RS23785 (6856) | 6856..7560 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23790 (7614) | 7614..8081 | + | 468 | Protein_10 | conjugal transfer protein | - |
| PIC02_RS23795 (8326) | 8326..8442 | + | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| PIC02_RS23800 (8458) | 8458..10377 | + | 1920 | WP_025989258.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| PIC02_RS23805 (10496) | 10496..10663 | + | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| PIC02_RS23810 (10930) | 10930..11634 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23815 (11687) | 11687..11935 | + | 249 | Protein_15 | hypothetical protein | - |
| PIC02_RS23820 (12081) | 12081..12944 | + | 864 | WP_000612791.1 | SDR family oxidoreductase | - |
| PIC02_RS23825 (13078) | 13078..13782 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23830 (13934) | 13934..14479 | + | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| PIC02_RS23835 (14616) | 14616..15188 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| PIC02_RS23840 (15225) | 15225..16616 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| PIC02_RS23845 (16649) | 16649..17077 | + | 429 | Protein_21 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| PIC02_RS23850 (17396) | 17396..18052 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| PIC02_RS23855 (18447) | 18447..19462 | + | 1016 | Protein_23 | IS3 family transposase ISEc36 | Transposase |
| PIC02_RS23860 (19505) | 19505..22432 | - | 2928 | Protein_24 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PIC02_RS23865 (22346) | 22346..22525 | + | 180 | WP_244756216.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PIC02_RS23870 (22491) | 22491..23255 | + | 765 | WP_072679250.1 | IS6 family transposase IS6100 | Transposase |
| PIC02_RS23875 (23748) | 23748..24332 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| PIC02_RS23880 (24332) | 24332..25570 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| PIC02_RS23885 (25567) | 25567..26472 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| PIC02_RS23890 (26594) | 26594..27298 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23895 (27363) | 27363..28043 | - | 681 | Protein_31 | IS91 family transposase ISAzo26 | Transposase |
| PIC02_RS23900 (28315) | 28315..29019 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23905 (29074) | 29074..29499 | + | 426 | Protein_33 | TetR/AcrR family transcriptional regulator | - |
| PIC02_RS23910 (29519) | 29519..30307 | + | 789 | WP_014839978.1 | winged helix-turn-helix domain-containing protein | - |
| PIC02_RS23915 (30307) | 30307..30825 | + | 519 | WP_014839979.1 | FidL-like protein | - |
| PIC02_RS23920 (30830) | 30830..31246 | - | 417 | WP_014839980.1 | Glutathione transferase FosA | ARG |
| PIC02_RS23925 (31632) | 31632..32336 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23930 (32386) | 32386..33129 | + | 744 | Protein_38 | Beta-lactamase TEM | ARG |
| PIC02_RS23935 (33388) | 33388..33864 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| PIC02_RS23940 (33911) | 33911..34786 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| PIC02_RS23945 (35208) | 35208..35912 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PIC02_RS23950 (35978) | 35978..36043 | + | 66 | Protein_42 | IS1 family transposase | - |
| PIC02_RS23955 (37492) | 37492..37726 | + | 235 | Protein_43 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PIC02_RS23960 (37854) | 37854..38057 | + | 204 | Protein_44 | hypothetical protein | - |
| PIC02_RS23965 (38258) | 38258..38608 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| PIC02_RS23970 (38611) | 38611..39573 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| PIC02_RS23975 (39720) | 39720..40013 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| PIC02_RS23980 (40090) | 40090..40773 | + | 684 | WP_000085883.1 | DNA methylase | - |
| PIC02_RS23985 (40774) | 40774..40995 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| PIC02_RS23990 (41009) | 41009..41443 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| PIC02_RS23995 (41494) | 41494..42270 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| PIC02_RS24000 (42688) | 42688..43113 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| PIC02_RS24005 (43160) | 43160..43582 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| PIC02_RS24010 (43579) | 43579..43770 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| PIC02_RS24015 (43984) | 43984..44139 | + | 156 | WP_159420149.1 | hypothetical protein | - |
| PIC02_RS24020 (44808) | 44808..45038 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| PIC02_RS24025 (45090) | 45090..46451 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| PIC02_RS24030 (46498) | 46498..47061 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| PIC02_RS24035 (47058) | 47058..47294 | + | 237 | WP_071849628.1 | hypothetical protein | - |
| PIC02_RS24040 (47213) | 47213..47464 | + | 252 | WP_242812820.1 | hypothetical protein | - |
| PIC02_RS24045 (47705) | 47705..47911 | + | 207 | WP_000547971.1 | hypothetical protein | - |
| PIC02_RS24050 (47937) | 47937..48476 | + | 540 | WP_009426937.1 | single-stranded DNA-binding protein | - |
| PIC02_RS24055 (48534) | 48534..48767 | + | 234 | WP_000005993.1 | DUF905 family protein | - |
| PIC02_RS24060 (48831) | 48831..50789 | + | 1959 | WP_024221812.1 | ParB/RepB/Spo0J family partition protein | - |
| PIC02_RS24065 (50844) | 50844..51278 | + | 435 | WP_072834353.1 | conjugation system SOS inhibitor PsiB | - |
| PIC02_RS24070 (51275) | 51275..52061 | + | 787 | Protein_66 | plasmid SOS inhibition protein A | - |
| PIC02_RS24075 (52006) | 52006..52194 | - | 189 | WP_123002541.1 | protein sok | - |
| - (52006) | 52006..52196 | + | 191 | NuclAT_0 | - | - |
| - (52006) | 52006..52196 | + | 191 | NuclAT_0 | - | - |
| - (52006) | 52006..52196 | + | 191 | NuclAT_0 | - | - |
| - (52006) | 52006..52196 | + | 191 | NuclAT_0 | - | - |
| PIC02_RS24080 (52244) | 52244..53613 | + | 1370 | WP_085947770.1 | IS3-like element IS150 family transposase | - |
| - (53638) | 53638..53676 | + | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (53638) | 53638..53676 | + | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (53638) | 53638..53676 | + | 39 | NuclAT_1 | - | Antitoxin Detail |
| - (53638) | 53638..53676 | + | 39 | NuclAT_1 | - | Antitoxin Detail |
| PIC02_RS24085 (53662) | 53662..53811 | + | 150 | Protein_69 | plasmid maintenance protein Mok | - |
| PIC02_RS24090 (53753) | 53753..53878 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PIC02_RS24095 (54099) | 54099..54329 | + | 231 | WP_106121197.1 | hypothetical protein | - |
| PIC02_RS24100 (54327) | 54327..54500 | - | 174 | Protein_72 | hypothetical protein | - |
| PIC02_RS24105 (54570) | 54570..54776 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| PIC02_RS24110 (54801) | 54801..55088 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| PIC02_RS24115 (55206) | 55206..56027 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| PIC02_RS24120 (56324) | 56324..56971 | - | 648 | WP_000614935.1 | hypothetical protein | VF |
| PIC02_RS24125 (57248) | 57248..57631 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PIC02_RS24130 (57822) | 57822..58508 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| PIC02_RS24135 (58602) | 58602..58829 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| PIC02_RS24140 (58863) | 58863..59228 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| PIC02_RS24145 (59243) | 59243..59554 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| PIC02_RS24150 (59576) | 59576..60142 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| PIC02_RS24155 (60129) | 60129..60857 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| PIC02_RS24160 (60857) | 60857..62284 | + | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PIC02_RS24165 (62274) | 62274..62864 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PIC02_RS24170 (62851) | 62851..63048 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| PIC02_RS24175 (63060) | 63060..63311 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| PIC02_RS24180 (63308) | 63308..63823 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PIC02_RS24185 (63958) | 63958..64179 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| PIC02_RS24190 (64339) | 64339..66966 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| PIC02_RS24195 (66963) | 66963..67349 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| PIC02_RS24200 (67346) | 67346..67978 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| PIC02_RS24205 (67975) | 67975..68967 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| PIC02_RS24210 (68994) | 68994..69302 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| PIC02_RS24215 (69365) | 69365..69886 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| PIC02_RS24220 (69913) | 69913..70551 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PIC02_RS24225 (70548) | 70548..70919 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| PIC02_RS24230 (70945) | 70945..71367 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| PIC02_RS24235 (71364) | 71364..73214 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PIC02_RS24240 (73241) | 73241..73498 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| PIC02_RS24245 (73491) | 73491..74234 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PIC02_RS24250 (74395) | 74395..74631 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PIC02_RS24255 (74618) | 74618..75163 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PIC02_RS24260 (75153) | 75153..75467 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| PIC02_RS24265 (75421) | 75421..75813 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| PIC02_RS24270 (75800) | 75800..77173 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| PIC02_RS24275 (77170) | 77170..79986 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PIC02_RS24280 (80019) | 80019..80540 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| PIC02_RS24285 (80565) | 80565..81296 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| PIC02_RS24290 (81499) | 81499..82236 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| PIC02_RS24295 (82287) | 82287..84521 | + | 2235 | WP_032316743.1 | type IV conjugative transfer system coupling protein TraD | - |
| PIC02_RS24300 (84521) | 84521..89791 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
| PIC02_RS24305 (89811) | 89811..90557 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| PIC02_RS24310 (90612) | 90612..91172 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| PIC02_RS24315 (91304) | 91304..91504 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| PIC02_RS24320 (91890) | 91890..92489 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| PIC02_RS24325 (92551) | 92551..92883 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (93084) | 93084..93143 | - | 60 | NuclAT_2 | - | - |
| - (93084) | 93084..93143 | - | 60 | NuclAT_2 | - | - |
| - (93084) | 93084..93143 | - | 60 | NuclAT_2 | - | - |
| - (93084) | 93084..93143 | - | 60 | NuclAT_2 | - | - |
| PIC02_RS24330 (93188) | 93188..93337 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|