MGE detailed information
MGE type: Conjugative plasmid MGE length: 82763 bp
Accession: NZ_CP116147 Location: 1..82763 Organism: Escherichia coli strain DETEC-P622 Replicon: plasmid pDETEC60
Accession: NZ_CP116147 Location: 1..82763 Organism: Escherichia coli strain DETEC-P622 Replicon: plasmid pDETEC60
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PIB88_RS25365 () | 101..349 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| PIB88_RS25370 () | 594..668 | + | 75 | WP_001375168.1 | RepA leader peptide Tap | - |
| PIB88_RS25375 () | 661..1518 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| PIB88_RS25380 () | 2457..2918 | + | 462 | WP_072643484.1 | histidine phosphatase family protein | - |
| PIB88_RS25385 () | 3074..4273 | - | 1200 | WP_000948429.1 | IS91 family transposase ISSbo1 | Transposase |
| PIB88_RS25390 () | 4283..4471 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| PIB88_RS25395 () | 4600..6222 | + | 1623 | WP_271287831.1 | P-loop NTPase fold protein | - |
| PIB88_RS25400 () | 6272..7171 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| PIB88_RS25405 () | 7161..7451 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| PIB88_RS25410 () | 7747..7977 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PIB88_RS25415 () | 7974..8390 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PIB88_RS25420 () | 8552..10690 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| PIB88_RS25425 () | 11044..11301 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| PIB88_RS25430 () | 11301..11891 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| PIB88_RS25435 () | 12154..13710 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| PIB88_RS25440 () | 13902..14519 | + | 618 | WP_000521603.1 | ProQ/FINO family protein | - |
| PIB88_RS25445 () | 14812..15849 | - | 1038 | WP_044502555.1 | permease | - |
| PIB88_RS25450 () | 15954..16277 | + | 324 | WP_001175594.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| PIB88_RS25455 () | 16476..17180 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| PIB88_RS25460 () | 17186..17914 | + | 729 | WP_152921961.1 | replication initiation protein | - |
| PIB88_RS25465 () | 18452..19156 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| PIB88_RS25470 () | 19282..20037 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| PIB88_RS25475 () | 20207..21067 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PIB88_RS25480 () | 21250..21807 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PIB88_RS25485 () | 22112..22222 | - | 111 | Protein_24 | IS6 family transposase | - |
| PIB88_RS25490 () | 22288..22992 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| PIB88_RS25495 () | 23044..23769 | + | 726 | Protein_26 | Beta-lactamase TEM | ARG |
| PIB88_RS25500 () | 24028..24504 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| PIB88_RS25505 () | 24551..25426 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| PIB88_RS25510 () | 25848..26552 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| PIB88_RS25515 () | 26618..26683 | + | 66 | Protein_30 | IS1 family transposase | - |
| PIB88_RS25520 () | 28132..28366 | + | 235 | Protein_31 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PIB88_RS25525 () | 28494..28697 | + | 204 | Protein_32 | hypothetical protein | - |
| PIB88_RS25530 () | 28898..29248 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| PIB88_RS25535 () | 29251..30213 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| PIB88_RS25540 () | 30360..30653 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| PIB88_RS25545 () | 30730..31413 | + | 684 | WP_000085883.1 | DNA methylase | - |
| PIB88_RS25550 () | 31414..31635 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| PIB88_RS25555 () | 31649..32083 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| PIB88_RS25560 () | 32134..32910 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| PIB88_RS25565 () | 33328..33753 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| PIB88_RS25570 () | 33800..34222 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| PIB88_RS25575 () | 34219..34410 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| PIB88_RS25580 () | 35448..35678 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| PIB88_RS25585 () | 35730..37091 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| PIB88_RS25590 () | 37138..37701 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| PIB88_RS25595 () | 37787..38248 | - | 462 | Protein_46 | hypothetical protein | - |
| PIB88_RS25600 () | 38550..39077 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| PIB88_RS25605 () | 39135..39368 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| PIB88_RS25610 () | 39429..41452 | + | 2024 | Protein_49 | ParB/RepB/Spo0J family partition protein | - |
| PIB88_RS25615 () | 41521..41955 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| PIB88_RS25620 () | 41952..42714 | + | 763 | Protein_51 | plasmid SOS inhibition protein A | - |
| - () | 42683..42907 | + | 225 | NuclAT_0 | - | - |
| - () | 42683..42907 | + | 225 | NuclAT_0 | - | - |
| - () | 42683..42907 | + | 225 | NuclAT_0 | - | - |
| - () | 42683..42907 | + | 225 | NuclAT_0 | - | - |
| PIB88_RS25625 () | 42692..42871 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - | 42840..42905 | - | 66 | - | - | Antitoxin Detail |
| PIB88_RS25630 () | 42893..43042 | + | 150 | Protein_53 | plasmid maintenance protein Mok | - |
| PIB88_RS25635 () | 42984..43109 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| PIB88_RS25640 () | 43428..43724 | - | 297 | Protein_55 | hypothetical protein | - |
| PIB88_RS25645 () | 44024..44320 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| PIB88_RS25650 () | 44431..45252 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| PIB88_RS25655 () | 45549..46196 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| PIB88_RS25660 () | 46473..46856 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PIB88_RS25665 () | 47047..47733 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| PIB88_RS25670 () | 47827..48054 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| PIB88_RS25675 () | 48088..48453 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| PIB88_RS25680 () | 48468..48779 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| PIB88_RS25685 () | 48801..49367 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| PIB88_RS25690 () | 49354..50082 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| PIB88_RS25695 () | 50082..51509 | + | 1428 | WP_032297072.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PIB88_RS25700 () | 51499..52089 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| PIB88_RS25705 () | 52076..52273 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| PIB88_RS25710 () | 52285..52536 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| PIB88_RS25715 () | 52533..53048 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PIB88_RS25720 () | 53183..53404 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| PIB88_RS25725 () | 53564..56191 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| PIB88_RS25730 () | 56188..56574 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| PIB88_RS25735 () | 56571..57203 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| PIB88_RS25740 () | 57200..58192 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| PIB88_RS25745 () | 58219..58527 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| PIB88_RS25750 () | 58590..59111 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| PIB88_RS25755 () | 59138..59776 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PIB88_RS25760 () | 59773..60144 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| PIB88_RS25765 () | 60170..60592 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| PIB88_RS25770 () | 60589..62439 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PIB88_RS25775 () | 62466..62723 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| PIB88_RS25780 () | 62716..63459 | + | 744 | WP_015059017.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PIB88_RS25785 () | 63620..63856 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PIB88_RS25790 () | 63843..64388 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PIB88_RS25795 () | 64378..64692 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| PIB88_RS25800 () | 64646..65038 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| PIB88_RS25805 () | 65025..66398 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| PIB88_RS25810 () | 66395..69211 | + | 2817 | WP_271287830.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PIB88_RS25815 () | 69244..69765 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| PIB88_RS25820 () | 69790..70521 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| PIB88_RS25825 () | 70724..71461 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| PIB88_RS25830 () | 71512..73764 | + | 2253 | WP_061093448.1 | type IV conjugative transfer system coupling protein TraD | - |
| PIB88_RS25835 () | 73764..79034 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
| PIB88_RS25840 () | 79054..79800 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| PIB88_RS25845 () | 79855..80415 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| PIB88_RS25850 () | 80547..80747 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| PIB88_RS25855 () | 81133..81732 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| PIB88_RS25860 () | 81794..82126 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - () | 82327..82386 | - | 60 | NuclAT_1 | - | - |
| - () | 82327..82386 | - | 60 | NuclAT_1 | - | - |
| - () | 82327..82386 | - | 60 | NuclAT_1 | - | - |
| - () | 82327..82386 | - | 60 | NuclAT_1 | - | - |
| PIB88_RS25865 () | 82431..82580 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|