MGE detailed information
MGE type: Conjugative plasmid MGE length: 119165 bp
Accession: NZ_CP115709 Location: 1..119165 Organism: Klebsiella pneumoniae strain CPE16 Replicon: plasmid pCPE16_3
Accession: NZ_CP115709 Location: 1..119165 Organism: Klebsiella pneumoniae strain CPE16 Replicon: plasmid pCPE16_3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PGD48_RS26990 (PGD48_26985) | 1..1014 | + | 1014 | WP_040120366.1 | plasmid replication initiator RepA | - |
| PGD48_RS26995 (PGD48_26990) | 1988..2314 | - | 327 | WP_004201125.1 | C2H2-type zinc finger protein | - |
| PGD48_RS27000 (PGD48_26995) | 2496..2777 | + | 282 | WP_001568067.1 | hypothetical protein | - |
| PGD48_RS27005 (PGD48_27000) | 2831..3442 | + | 612 | WP_000176305.1 | DUF2913 family protein | - |
| PGD48_RS27010 (PGD48_27005) | 3439..3549 | - | 111 | Protein_4 | hypothetical protein | - |
| PGD48_RS27015 (PGD48_27010) | 3591..4295 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| PGD48_RS27020 (PGD48_27015) | 4359..4688 | + | 330 | WP_004201171.1 | divalent-cation tolerance protein CutA | - |
| PGD48_RS27025 (PGD48_27020) | 4693..5067 | + | 375 | Protein_7 | protein-disulfide reductase DsbD family protein | - |
| PGD48_RS27030 (PGD48_27025) | 5167..5724 | + | 558 | Protein_8 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| PGD48_RS27035 (PGD48_27030) | 5735..6373 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| PGD48_RS27040 (PGD48_27035) | 6378..6743 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| PGD48_RS27045 (PGD48_27040) | 6747..7559 | - | 813 | WP_004201164.1 | Metallo-beta-lactamase type 2 | ARG |
| PGD48_RS27050 (PGD48_27045) | 7774..8805 | - | 1032 | WP_071905678.1 | IS630 family transposase ISSpu2 | Transposase |
| PGD48_RS27055 (PGD48_27050) | 8905..9783 | - | 879 | Protein_13 | IS30 family transposase ISAba125 | Transposase |
| PGD48_RS27060 (PGD48_27055) | 9992..10771 | - | 780 | WP_014386410.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| PGD48_RS27065 (PGD48_27060) | 10877..11047 | - | 171 | Protein_15 | integrase core domain-containing protein | - |
| PGD48_RS27070 (PGD48_27065) | 11187..11732 | + | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| PGD48_RS27075 (PGD48_27070) | 11869..12441 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| PGD48_RS27080 (PGD48_27075) | 12478..13869 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| PGD48_RS27085 (PGD48_27080) | 13902..14330 | + | 429 | Protein_19 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| PGD48_RS27090 (PGD48_27085) | 14649..15305 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| PGD48_RS27095 (PGD48_27090) | 15700..16715 | + | 1016 | Protein_21 | IS3 family transposase ISEc36 | Transposase |
| PGD48_RS27100 (PGD48_27095) | 16758..19541 | - | 2784 | Protein_22 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PGD48_RS27105 (PGD48_27100) | 19555..19899 | + | 345 | Protein_23 | WbuC family cupin fold metalloprotein | - |
| PGD48_RS27110 (PGD48_27105) | 19946..20821 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| PGD48_RS27115 (PGD48_27110) | 21077..22339 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| PGD48_RS27120 (PGD48_27115) | 22521..22739 | - | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| PGD48_RS27125 (PGD48_27120) | 22903..23460 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PGD48_RS27130 (PGD48_27125) | 23694..24248 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| PGD48_RS27135 (PGD48_27130) | 24318..25106 | + | 789 | WP_001206315.1 | Streptomycin 3''-adenylyltransferase | ARG |
| PGD48_RS27140 (PGD48_27135) | 25166..25990 | + | 825 | Protein_30 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| PGD48_RS27145 (PGD48_27140) | 26190..26507 | + | 318 | Protein_31 | Tn3 family transposase TnpR_Tn3 | Transposase |
| PGD48_RS27150 (PGD48_27145) | 26690..27550 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| PGD48_RS27155 (PGD48_27150) | 27700..28071 | - | 372 | Protein_33 | IS6 family transposase IS15DII | Transposase |
| PGD48_RS27160 (PGD48_27155) | 28136..29386 | - | 1251 | Protein_34 | transposase | - |
| PGD48_RS27165 (PGD48_27160) | 29461..30129 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| PGD48_RS27170 (PGD48_27165) | 30165..30401 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| PGD48_RS27175 (PGD48_27170) | 30398..30760 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| PGD48_RS27180 (PGD48_27175) | 30778..32472 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| PGD48_RS27185 (PGD48_27180) | 32524..32946 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| PGD48_RS27190 (PGD48_27185) | 32982..33092 | - | 111 | Protein_40 | mercuric transport protein periplasmic component | - |
| PGD48_RS27200 (PGD48_27195) | 33860..34549 | - | 690 | Protein_42 | AAA family ATPase | - |
| PGD48_RS27205 (PGD48_27200) | 34623..35039 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| PGD48_RS27210 (PGD48_27205) | 35036..35266 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| PGD48_RS27215 (PGD48_27210) | 35223..35682 | + | 460 | Protein_45 | hypothetical protein | - |
| PGD48_RS27220 (PGD48_27215) | 36169..36477 | + | 309 | WP_004152336.1 | hypothetical protein | - |
| PGD48_RS27225 (PGD48_27220) | 36505..36834 | + | 330 | WP_004152337.1 | hypothetical protein | - |
| PGD48_RS27230 (PGD48_27225) | 36860..37258 | + | 399 | WP_004171440.1 | hypothetical protein | - |
| PGD48_RS27235 (PGD48_27230) | 37265..37597 | + | 333 | WP_004152339.1 | hypothetical protein | - |
| PGD48_RS27240 (PGD48_27235) | 37597..38379 | + | 783 | WP_004152340.1 | site-specific integrase | - |
| PGD48_RS27245 (PGD48_27240) | 39271..39501 | - | 231 | WP_011977773.1 | hypothetical protein | - |
| PGD48_RS27250 (PGD48_27245) | 39593..40066 | - | 474 | WP_004152341.1 | YkgJ family cysteine cluster protein | - |
| PGD48_RS27255 (PGD48_27250) | 40186..41454 | - | 1269 | WP_086530243.1 | ISL3 family transposase ISKpn25 | Transposase |
| PGD48_RS27260 (PGD48_27255) | 41459..44716 | - | 3258 | WP_004152343.1 | DEAD/DEAH box helicase family protein | - |
| PGD48_RS27265 (PGD48_27260) | 44717..46033 | - | 1317 | WP_004152344.1 | restriction endonuclease subunit S | - |
| PGD48_RS27270 (PGD48_27265) | 46030..48057 | - | 2028 | WP_004152345.1 | class I SAM-dependent DNA methyltransferase | - |
| PGD48_RS27275 (PGD48_27270) | 48169..48384 | - | 216 | WP_004227314.1 | hypothetical protein | - |
| PGD48_RS27280 (PGD48_27275) | 48609..48941 | - | 333 | WP_004152347.1 | hypothetical protein | - |
| PGD48_RS27285 (PGD48_27280) | 49318..50292 | - | 975 | WP_004152348.1 | ParB family protein | - |
| PGD48_RS27290 (PGD48_27285) | 50289..51494 | - | 1206 | WP_004152349.1 | Plasmid partition protein A | VF |
| PGD48_RS27295 (PGD48_27290) | 51816..52712 | - | 897 | WP_004152350.1 | RepB family plasmid replication initiator protein | - |
| PGD48_RS27300 (PGD48_27295) | 53113..54384 | - | 1272 | WP_004152351.1 | Y-family DNA polymerase | - |
| PGD48_RS27305 (PGD48_27300) | 54384..54815 | - | 432 | WP_004152352.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| PGD48_RS27310 (PGD48_27305) | 55047..56018 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| PGD48_RS27315 (PGD48_27310) | 56021..56692 | + | 672 | WP_004152354.1 | plasmid partitioning/stability family protein | - |
| PGD48_RS27320 (PGD48_27315) | 56753..56983 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| PGD48_RS27325 (PGD48_27320) | 57179..57348 | + | 170 | Protein_67 | hypothetical protein | - |
| PGD48_RS27330 (PGD48_27325) | 57420..58121 | + | 702 | WP_001568041.1 | DNA methylase | - |
| PGD48_RS27335 (PGD48_27330) | 58121..58342 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| PGD48_RS27340 (PGD48_27335) | 58352..58771 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| PGD48_RS27345 (PGD48_27340) | 58825..59592 | + | 768 | WP_032445745.1 | hypothetical protein | - |
| PGD48_RS27350 (PGD48_27345) | 60225..60653 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| PGD48_RS27355 (PGD48_27350) | 60696..61202 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| PGD48_RS27360 (PGD48_27355) | 61245..61436 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| PGD48_RS27365 (PGD48_27360) | 61624..61878 | + | 255 | WP_032445741.1 | DNA polymerase III subunit theta | - |
| PGD48_RS27370 (PGD48_27365) | 61913..62230 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| PGD48_RS27375 (PGD48_27370) | 63026..63568 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| PGD48_RS27380 (PGD48_27375) | 63617..63865 | + | 249 | WP_032445658.1 | DUF905 domain-containing protein | - |
| PGD48_RS27385 (PGD48_27380) | 63935..65992 | + | 2058 | WP_040120383.1 | ParB/RepB/Spo0J family partition protein | - |
| PGD48_RS27390 (PGD48_27385) | 66037..66468 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| PGD48_RS27395 (PGD48_27390) | 66465..67193 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| PGD48_RS27400 (PGD48_27395) | 67190..67516 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| PGD48_RS27405 (PGD48_27400) | 67572..67946 | + | 375 | WP_040120382.1 | hypothetical protein | - |
| PGD48_RS27410 (PGD48_27405) | 68150..69519 | + | 1370 | WP_085949440.1 | IS3 family transposase ISKpn8 | Transposase |
| PGD48_RS27415 (PGD48_27410) | 69577..70650 | - | 1074 | WP_013609528.1 | IS481 family transposase ISKpn28 | Transposase |
| PGD48_RS27420 (PGD48_27415) | 70761..70880 | + | 120 | WP_159376494.1 | type I toxin-antitoxin system Hok family toxin | - |
| PGD48_RS27425 (PGD48_27420) | 71579..71851 | + | 273 | WP_032445785.1 | hypothetical protein | - |
| PGD48_RS27430 (PGD48_27425) | 71848..72198 | + | 351 | WP_032445787.1 | hypothetical protein | - |
| PGD48_RS27435 (PGD48_27430) | 72213..72530 | + | 318 | WP_032445789.1 | hypothetical protein | - |
| PGD48_RS27440 (PGD48_27435) | 73371..73727 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| PGD48_RS27445 (PGD48_27440) | 73788..74000 | + | 213 | WP_032445756.1 | hypothetical protein | - |
| PGD48_RS27450 (PGD48_27445) | 74011..74235 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| PGD48_RS27455 (PGD48_27450) | 74316..74636 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| PGD48_RS27460 (PGD48_27455) | 74626..74904 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| PGD48_RS27465 (PGD48_27460) | 74905..75318 | + | 414 | WP_040120381.1 | helix-turn-helix domain-containing protein | - |
| PGD48_RS27470 (PGD48_27465) | 76036..76416 | + | 381 | WP_020802391.1 | hypothetical protein | - |
| PGD48_RS27475 (PGD48_27470) | 76483..76830 | + | 348 | WP_032445771.1 | hypothetical protein | - |
| PGD48_RS27480 (PGD48_27475) | 76925..77071 | + | 147 | WP_004152750.1 | hypothetical protein | - |
| PGD48_RS27485 (PGD48_27480) | 77122..77955 | + | 834 | WP_032445769.1 | N-6 DNA methylase | - |
| PGD48_RS27490 (PGD48_27485) | 78772..79593 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| PGD48_RS27495 (PGD48_27490) | 79626..79955 | + | 330 | WP_011977736.1 | DUF5983 family protein | - |
| PGD48_RS27500 (PGD48_27495) | 79988..80473 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| PGD48_RS27505 (PGD48_27500) | 80905..81297 | + | 393 | WP_004194114.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| PGD48_RS27510 (PGD48_27505) | 81527..82228 | + | 702 | WP_040120380.1 | hypothetical protein | - |
| PGD48_RS27515 (PGD48_27510) | 82314..82514 | + | 201 | WP_046664192.1 | TraY domain-containing protein | - |
| PGD48_RS27520 (PGD48_27515) | 82582..82950 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| PGD48_RS27525 (PGD48_27520) | 82964..83269 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| PGD48_RS27530 (PGD48_27525) | 83289..83855 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| PGD48_RS27535 (PGD48_27530) | 83842..84582 | + | 741 | WP_040120379.1 | type-F conjugative transfer system secretin TraK | - |
| PGD48_RS27540 (PGD48_27535) | 84582..86006 | + | 1425 | WP_040120378.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| PGD48_RS27545 (PGD48_27540) | 86078..86662 | + | 585 | WP_040120377.1 | type IV conjugative transfer system lipoprotein TraV | - |
| PGD48_RS27550 (PGD48_27545) | 86985..87203 | + | 219 | WP_004195468.1 | hypothetical protein | - |
| PGD48_RS27555 (PGD48_27550) | 87204..87515 | + | 312 | WP_029497417.1 | hypothetical protein | - |
| PGD48_RS27560 (PGD48_27555) | 87582..87986 | + | 405 | WP_004197817.1 | hypothetical protein | - |
| PGD48_RS27565 (PGD48_27560) | 88029..88181 | + | 153 | WP_224518895.1 | hypothetical protein | - |
| PGD48_RS27570 (PGD48_27565) | 88363..88761 | + | 399 | WP_023179972.1 | hypothetical protein | - |
| PGD48_RS27575 (PGD48_27570) | 88833..91472 | + | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| PGD48_RS27580 (PGD48_27575) | 91472..91861 | + | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| PGD48_RS27585 (PGD48_27580) | 91861..92496 | + | 636 | WP_029497419.1 | type-F conjugative transfer system protein TraW | - |
| PGD48_RS27590 (PGD48_27585) | 92531..92932 | + | 402 | WP_040120376.1 | hypothetical protein | - |
| PGD48_RS27595 (PGD48_27590) | 92929..93918 | + | 990 | WP_029497420.1 | conjugal transfer pilus assembly protein TraU | - |
| PGD48_RS27600 (PGD48_27595) | 93931..94569 | + | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| PGD48_RS27605 (PGD48_27600) | 94628..96583 | + | 1956 | WP_040120375.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| PGD48_RS27610 (PGD48_27605) | 96615..96869 | + | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| PGD48_RS27615 (PGD48_27610) | 96847..97095 | + | 249 | WP_004152675.1 | hypothetical protein | - |
| PGD48_RS27620 (PGD48_27615) | 97108..97434 | + | 327 | WP_004144402.1 | hypothetical protein | - |
| PGD48_RS27625 (PGD48_27620) | 97455..98207 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| PGD48_RS27630 (PGD48_27625) | 98218..98457 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| PGD48_RS27635 (PGD48_27630) | 98429..98986 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| PGD48_RS27640 (PGD48_27635) | 99032..99475 | + | 444 | WP_014343488.1 | F-type conjugal transfer protein TrbF | - |
| PGD48_RS27645 (PGD48_27640) | 99453..100832 | + | 1380 | WP_072198320.1 | conjugal transfer pilus assembly protein TraH | - |
| PGD48_RS27650 (PGD48_27645) | 100832..103681 | + | 2850 | WP_040120373.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| PGD48_RS27655 (PGD48_27650) | 103687..104214 | + | 528 | WP_040120388.1 | conjugal transfer protein TraS | - |
| PGD48_RS27660 (PGD48_27655) | 104403..105134 | + | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| PGD48_RS27665 (PGD48_27660) | 105327..106016 | + | 690 | WP_072198322.1 | hypothetical protein | - |
| PGD48_RS27670 (PGD48_27665) | 106145..108457 | + | 2313 | WP_040120372.1 | type IV conjugative transfer system coupling protein TraD | - |
| PGD48_RS27675 (PGD48_27670) | 108457..113718 | + | 5262 | WP_040120371.1 | Multifunctional conjugation protein TraI | Relaxase |
| PGD48_RS27680 (PGD48_27675) | 113798..114523 | + | 726 | WP_040120370.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| PGD48_RS27685 (PGD48_27680) | 114595..115188 | + | 594 | WP_004152380.1 | fertility inhibition protein FinO | - |
| PGD48_RS27690 (PGD48_27685) | 115349..115951 | + | 603 | WP_064750782.1 | PIN domain-containing protein | - |
| PGD48_RS27695 (PGD48_27690) | 116001..116645 | + | 645 | WP_004153014.1 | hypothetical protein | - |
| PGD48_RS27700 (PGD48_27695) | 116701..117351 | + | 651 | WP_040120368.1 | DUF2726 domain-containing protein | - |
| PGD48_RS27705 (PGD48_27700) | 117348..117656 | + | 309 | WP_040120367.1 | hypothetical protein | - |
| PGD48_RS27710 (PGD48_27705) | 117760..118311 | + | 552 | WP_013609507.1 | Cardiolipin synthase A | VF |
| PGD48_RS27715 (PGD48_27710) | 118429..118698 | + | 270 | WP_072198323.1 | replication regulatory protein RepA | - |
| PGD48_RS27720 (PGD48_27715) | 118930..119007 | + | 78 | WP_071905679.1 | RepA leader peptide Tap | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|