MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 97481 bp
Accession: NZ_CP115183 Location: 2057275..2154755 Organism: Clostridioides difficile R20291 Replicon: chromosome
Accession: NZ_CP115183 Location: 2057275..2154755 Organism: Clostridioides difficile R20291 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O9S30_RS09645 (O9S30_09645) | 2052765..2054306 | + | 1542 | WP_079754356.1 | SdrD B-like domain-containing protein | - |
| O9S30_RS09650 (O9S30_09650) | 2054325..2054606 | + | 282 | WP_009891898.1 | CD1845 family protein | - |
| O9S30_RS09655 (O9S30_09655) | 2054692..2055714 | + | 1023 | WP_009891897.1 | DUF6017 domain-containing protein | - |
| O9S30_RS09660 (O9S30_09660) | 2055716..2056201 | + | 486 | WP_009891896.1 | PcfB family protein | - |
| O9S30_RS09665 (O9S30_09665) | 2056198..2057184 | + | 987 | Protein_1820 | type IV secretory system conjugative DNA transfer family protein | - |
| O9S30_RS09670 (O9S30_09670) | 2057275..2059155 | + | 1881 | WP_012816185.1 | hypothetical protein ; Integrase | Integrase |
| O9S30_RS09675 (O9S30_09675) | 2059182..2059535 | + | 354 | WP_012816186.1 | TnpV protein | - |
| O9S30_RS09680 (O9S30_09680) | 2059552..2059851 | + | 300 | WP_004612693.1 | hypothetical protein | - |
| O9S30_RS09685 (O9S30_09685) | 2059879..2060247 | - | 369 | WP_012816188.1 | helix-turn-helix transcriptional regulator | - |
| O9S30_RS09690 (O9S30_09690) | 2060392..2060580 | + | 189 | WP_007884040.1 | helix-turn-helix domain-containing protein | - |
| O9S30_RS09695 (O9S30_09695) | 2060573..2061265 | + | 693 | WP_024738629.1 | Transcriptional regulatory protein WalR | VF |
| O9S30_RS09700 (O9S30_09700) | 2061271..2062188 | + | 918 | WP_012816190.1 | HAMP domain-containing sensor histidine kinase | - |
| O9S30_RS09705 (O9S30_09705) | 2062323..2063249 | + | 927 | WP_104732837.1 | Bacitracin transport ATP-binding protein BcrA | VF |
| O9S30_RS09710 (O9S30_09710) | 2063242..2064027 | + | 786 | WP_012816192.1 | ABC transporter permease | - |
| O9S30_RS09715 (O9S30_09715) | 2064030..2064809 | + | 780 | WP_002594767.1 | ABC transporter permease | - |
| O9S30_RS09720 (O9S30_09720) | 2064817..2065278 | + | 462 | WP_012816193.1 | hypothetical protein | - |
| O9S30_RS09725 (O9S30_09725) | 2065723..2066136 | + | 414 | WP_012816194.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| O9S30_RS09730 (O9S30_09730) | 2066238..2066690 | + | 453 | WP_012816195.1 | sigma-24 (feci) | - |
| O9S30_RS09735 (O9S30_09735) | 2066701..2067162 | + | 462 | WP_009296689.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| O9S30_RS09740 (O9S30_09740) | 2067191..2067481 | + | 291 | WP_024739841.1 | DUF3847 domain-containing protein | - |
| O9S30_RS09745 (O9S30_09745) | 2067668..2069113 | + | 1446 | WP_104732839.1 | MobQ family relaxase | - |
| O9S30_RS09750 (O9S30_09750) | 2069221..2069511 | - | 291 | WP_002596328.1 | type II toxin-antitoxin system YafQ family toxin | Toxin Detail |
| O9S30_RS09755 (O9S30_09755) | 2069508..2069786 | - | 279 | WP_005924829.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin Detail |
| O9S30_RS09760 (O9S30_09760) | 2069913..2070311 | + | 399 | WP_012816198.1 | cysteine-rich VLP domain-containing protein | - |
| O9S30_RS09765 (O9S30_09765) | 2070425..2071159 | + | 735 | WP_012816199.1 | phage replisome organizer N-terminal domain-containing protein | - |
| O9S30_RS09770 (O9S30_09770) | 2071156..2072019 | + | 864 | WP_104732840.1 | IS21 family transposase ISBlo1 | Transposase |
| O9S30_RS09775 (O9S30_09775) | 2072063..2072257 | + | 195 | WP_104732841.1 | transposon-encoded TnpW family protein | - |
| O9S30_RS09780 (O9S30_09780) | 2072335..2072700 | + | 366 | WP_104732842.1 | hypothetical protein | - |
| O9S30_RS09785 (O9S30_09785) | 2072795..2073376 | + | 582 | Protein_1844 | TraM recognition domain-containing protein | - |
| O9S30_RS09790 (O9S30_09790) | 2073474..2073851 | + | 378 | WP_009891894.1 | TnpV protein | - |
| O9S30_RS09795 (O9S30_09795) | 2073865..2074146 | + | 282 | WP_009891893.1 | hypothetical protein | - |
| O9S30_RS09800 (O9S30_09800) | 2074268..2075116 | - | 849 | WP_009891891.1 | helix-turn-helix transcriptional regulator | - |
| O9S30_RS09805 (O9S30_09805) | 2075293..2075775 | + | 483 | WP_012816202.1 | hypothetical protein | - |
| O9S30_RS09810 (O9S30_09810) | 2075759..2076064 | + | 306 | WP_074014306.1 | molecular chaperone | - |
| O9S30_RS09815 (O9S30_09815) | 2076492..2077736 | + | 1245 | WP_021422885.1 | hypothetical protein | - |
| O9S30_RS09820 (O9S30_09820) | 2077752..2078438 | + | 687 | WP_074014307.1 | CHC2 zinc finger domain-containing protein | - |
| O9S30_RS09825 (O9S30_09825) | 2078398..2079756 | + | 1359 | WP_009891879.1 | virulence-associated E family protein | - |
| O9S30_RS09830 (O9S30_09830) | 2080024..2080191 | + | 168 | WP_009891878.1 | hypothetical protein | - |
| O9S30_RS09835 (O9S30_09835) | 2080264..2081916 | + | 1653 | WP_012816204.1 | hypothetical protein ; Integrase | Integrase |
| O9S30_RS09840 (O9S30_09840) | 2081964..2082419 | - | 456 | WP_009901261.1 | hypothetical protein | - |
| O9S30_RS09845 (O9S30_09845) | 2082443..2084116 | - | 1674 | WP_009893984.1 | hypothetical protein ; Integrase | Integrase |
| O9S30_RS09850 (O9S30_09850) | 2084194..2084367 | - | 174 | WP_002604472.1 | transposon-encoded TnpW family protein | - |
| O9S30_RS09855 (O9S30_09855) | 2084826..2085068 | - | 243 | WP_002604473.1 | helix-turn-helix domain-containing protein | - |
| O9S30_RS09860 (O9S30_09860) | 2085052..2085489 | - | 438 | WP_002604474.1 | sigma-70 family RNA polymerase sigma factor | - |
| O9S30_RS09865 (O9S30_09865) | 2085963..2086946 | - | 984 | WP_002584956.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| O9S30_RS09870 (O9S30_09870) | 2086963..2087148 | - | 186 | WP_003431289.1 | cysteine-rich KTR domain-containing protein | - |
| O9S30_RS09875 (O9S30_09875) | 2087759..2087920 | + | 162 | Protein_1862 | helix-turn-helix transcriptional regulator | - |
| O9S30_RS09880 (O9S30_09880) | 2088191..2088901 | - | 711 | WP_009891854.1 | LytTR family DNA-binding domain-containing protein | - |
| O9S30_RS09885 (O9S30_09885) | 2088906..2089079 | - | 174 | WP_002576203.1 | helix-turn-helix domain-containing protein | - |
| O9S30_RS09890 (O9S30_09890) | 2089221..2089454 | + | 234 | Protein_1865 | conjugal transfer protein TraG | - |
| O9S30_RS09895 (O9S30_09895) | 2089618..2089929 | + | 312 | WP_009891846.1 | single-stranded DNA-binding protein | - |
| O9S30_RS09900 (O9S30_09900) | 2089933..2090085 | + | 153 | Protein_1867 | Maff2 family protein | - |
| O9S30_RS09905 (O9S30_09905) | 2090247..2090519 | + | 273 | WP_009274451.1 | helix-turn-helix domain-containing protein | - |
| O9S30_RS09910 (O9S30_09910) | 2090479..2090856 | + | 378 | WP_009274452.1 | TnpV protein | - |
| O9S30_RS09915 (O9S30_09915) | 2090973..2091407 | + | 435 | WP_009274453.1 | MarR family transcriptional regulator | - |
| O9S30_RS09920 (O9S30_09920) | 2091400..2092701 | + | 1302 | WP_012816206.1 | MATE family efflux transporter | - |
| O9S30_RS09925 (O9S30_09925) | 2092795..2093601 | - | 807 | WP_012816207.1 | helix-turn-helix domain-containing protein | - |
| O9S30_RS09930 (O9S30_09930) | 2094085..2094273 | + | 189 | WP_055058411.1 | hypothetical protein | - |
| O9S30_RS09935 (O9S30_09935) | 2094270..2094611 | + | 342 | WP_003020305.1 | DeoR family transcriptional regulator | - |
| O9S30_RS09940 (O9S30_09940) | 2094604..2094900 | + | 297 | WP_012816208.1 | DUF3847 domain-containing protein | - |
| O9S30_RS09945 (O9S30_09945) | 2095200..2095343 | + | 144 | WP_009274458.1 | hypothetical protein | - |
| O9S30_RS09950 (O9S30_09950) | 2095531..2097111 | + | 1581 | WP_042520383.1 | MobQ family relaxase | - |
| O9S30_RS09955 (O9S30_09955) | 2097177..2097821 | + | 645 | WP_042520382.1 | CHC2 zinc finger domain-containing protein | - |
| O9S30_RS09960 (O9S30_09960) | 2097790..2099127 | + | 1338 | WP_042520381.1 | virulence-associated E family protein | - |
| O9S30_RS09965 (O9S30_09965) | 2099369..2099566 | + | 198 | WP_004612761.1 | hypothetical protein | - |
| O9S30_RS09970 (O9S30_09970) | 2099567..2101237 | + | 1671 | WP_012816213.1 | hypothetical protein ; Integrase | Integrase |
| O9S30_RS09975 (O9S30_09975) | 2101328..2101411 | + | 84 | Protein_1882 | Maff2 family protein | - |
| O9S30_RS09980 (O9S30_09980) | 2101431..2102294 | + | 864 | WP_009893980.1 | CD0415/CD1112 family protein | - |
| O9S30_RS09985 (O9S30_09985) | 2102312..2102572 | + | 261 | WP_009888259.1 | hypothetical protein | - |
| O9S30_RS09990 (O9S30_09990) | 2102576..2102965 | + | 390 | WP_009888260.1 | PrgI family protein | - |
| O9S30_RS09995 (O9S30_09995) | 2102877..2105306 | + | 2430 | WP_009888261.1 | ATP-binding protein | - |
| O9S30_RS10000 (O9S30_10000) | 2105310..2107442 | + | 2133 | WP_009888262.1 | CHAP domain-containing protein | - |
| O9S30_RS10005 (O9S30_10005) | 2107454..2107693 | + | 240 | WP_009888263.1 | hypothetical protein | - |
| O9S30_RS10010 (O9S30_10010) | 2107668..2109209 | + | 1542 | WP_009893977.1 | DUF4366 domain-containing protein | - |
| O9S30_RS10015 (O9S30_10015) | 2109304..2111010 | + | 1707 | WP_009893975.1 | DNA topoisomerase 3 | - |
| O9S30_RS10020 (O9S30_10020) | 2111095..2111898 | + | 804 | WP_004804477.1 | KilA-N domain-containing protein | - |
| O9S30_RS10025 (O9S30_10025) | 2111981..2120710 | + | 8730 | WP_009893973.1 | DEAD/DEAH box helicase family protein | - |
| O9S30_RS10030 (O9S30_10030) | 2120753..2121412 | + | 660 | WP_010826392.1 | hypothetical protein | - |
| O9S30_RS10035 (O9S30_10035) | 2121552..2121782 | + | 231 | WP_009889816.1 | helix-turn-helix transcriptional regulator | - |
| O9S30_RS10040 (O9S30_10040) | 2121985..2123607 | + | 1623 | WP_009889819.1 | AAA family ATPase | - |
| O9S30_RS10045 (O9S30_10045) | 2123604..2124671 | + | 1068 | WP_009889821.1 | UvrD-helicase domain-containing protein | - |
| O9S30_RS10050 (O9S30_10050) | 2124699..2125160 | + | 462 | WP_009889823.1 | hypothetical protein | - |
| O9S30_RS10055 (O9S30_10055) | 2125150..2125956 | + | 807 | WP_009889825.1 | PQQ-like beta-propeller repeat protein | - |
| O9S30_RS10060 (O9S30_10060) | 2125992..2127323 | - | 1332 | WP_009889829.1 | relaxase/mobilization nuclease domain-containing protein | - |
| O9S30_RS10065 (O9S30_10065) | 2127329..2127679 | - | 351 | WP_009889831.1 | plasmid mobilization relaxosome protein MobC | - |
| O9S30_RS10070 (O9S30_10070) | 2128013..2129170 | + | 1158 | WP_009893966.1 | TlpA disulfide reductase family protein | - |
| O9S30_RS10075 (O9S30_10075) | 2129192..2129344 | + | 153 | WP_003426158.1 | CD1871A family CXXC motif-containing protein | - |
| O9S30_RS10080 (O9S30_10080) | 2129337..2130227 | + | 891 | WP_009889834.1 | 4Fe-4S binding protein | - |
| O9S30_RS10085 (O9S30_10085) | 2130246..2131523 | + | 1278 | WP_009889836.1 | ABC transporter permease | - |
| O9S30_RS10090 (O9S30_10090) | 2131533..2132189 | + | 657 | WP_003426165.1 | putative ABC transporter ATP-binding protein | VF |
| O9S30_RS10095 (O9S30_10095) | 2132189..2133565 | + | 1377 | WP_009893965.1 | ABC transporter permease | - |
| O9S30_RS10100 (O9S30_10100) | 2133663..2134316 | + | 654 | WP_009889840.1 | Transcriptional regulatory protein QseB | VF |
| O9S30_RS10105 (O9S30_10105) | 2134313..2135632 | + | 1320 | WP_009889841.1 | HAMP domain-containing sensor histidine kinase | - |
| O9S30_RS10110 (O9S30_10110) | 2136156..2136566 | + | 411 | WP_003426191.1 | sigma-70 family RNA polymerase sigma factor | - |
| O9S30_RS10115 (O9S30_10115) | 2137055..2137207 | + | 153 | WP_003426199.1 | hypothetical protein | - |
| O9S30_RS10120 (O9S30_10120) | 2137308..2142230 | + | 4923 | WP_263715057.1 | Tn3 family transposase TnpR_ISAcsp1 | Transposase |
| O9S30_RS10125 (O9S30_10125) | 2142687..2143034 | + | 348 | WP_003435528.1 | cupin domain-containing protein | - |
| O9S30_RS10130 (O9S30_10130) | 2143184..2144233 | - | 1050 | WP_003423932.1 | ABC transporter substrate-binding protein | - |
| O9S30_RS10135 (O9S30_10135) | 2144619..2145353 | + | 735 | WP_009889846.1 | class I SAM-dependent methyltransferase | - |
| O9S30_RS10140 (O9S30_10140) | 2145495..2145986 | - | 492 | WP_003428667.1 | prolyl-tRNA synthetase associated domain-containing protein | - |
| O9S30_RS10145 (O9S30_10145) | 2146335..2146718 | + | 384 | WP_009889847.1 | PBECR2 nuclease fold domain-containing protein | - |
| O9S30_RS10150 (O9S30_10150) | 2147224..2147607 | + | 384 | WP_003428669.1 | YtxH domain-containing protein | - |
| O9S30_RS10155 (O9S30_10155) | 2147609..2147959 | + | 351 | WP_003428670.1 | hypothetical protein | - |
| O9S30_RS10160 (O9S30_10160) | 2148053..2148511 | - | 459 | WP_003435468.1 | hypothetical protein | - |
| O9S30_RS10165 (O9S30_10165) | 2148556..2149344 | - | 789 | WP_003435466.1 | N-acetylmuramoyl-L-alanine amidase | - |
| O9S30_RS10170 (O9S30_10170) | 2149483..2149920 | - | 438 | WP_009889849.1 | cytidine/deoxycytidylate deaminase family protein | - |
| O9S30_RS10175 (O9S30_10175) | 2150154..2150288 | - | 135 | WP_009889851.1 | hypothetical protein | - |
| O9S30_RS10180 (O9S30_10180) | 2150742..2151251 | + | 510 | WP_009889853.1 | hypothetical protein | VF |
| O9S30_RS10185 (O9S30_10185) | 2151278..2151424 | + | 147 | Protein_1924 | site-specific integrase | - |
| O9S30_RS10190 (O9S30_10190) | 2152162..2152962 | - | 801 | WP_003435446.1 | ABC transporter permease | - |
| O9S30_RS10195 (O9S30_10195) | 2153157..2154755 | - | 1599 | WP_009893325.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| O9S30_RS10200 (O9S30_10200) | 2155083..2155259 | + | 177 | WP_009889863.1 | hypothetical protein | - |
| O9S30_RS10205 (O9S30_10205) | 2155433..2156563 | + | 1131 | WP_009893327.1 | 1-propanol dehydrogenase PduQ | - |
| O9S30_RS10210 (O9S30_10210) | 2156804..2157154 | + | 351 | WP_009893329.1 | BMC domain-containing protein | - |
| O9S30_RS10215 (O9S30_10215) | 2157162..2157611 | + | 450 | WP_009889866.1 | EutP/PduV family microcompartment system protein | - |
| O9S30_RS10220 (O9S30_10220) | 2157713..2158288 | + | 576 | WP_003423977.1 | response regulator | - |
| O9S30_RS10225 (O9S30_10225) | 2158281..2159690 | + | 1410 | WP_009889869.1 | histidine kinase N-terminal domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|---|---|---|---|---|---|
| Clostridium difficile R20291 | Integrative and Conjugative Element | TA10095 | NC_013316 | 2043677..2141157 | 0 |