MGE detailed information
MGE type: Conjugative plasmid MGE length: 103507 bp
Accession: NZ_CP113187 Location: 1..103507 Organism: Klebsiella pneumoniae strain SYCC2 Replicon: plasmid pSYCC2_mcr-8_103k
Accession: NZ_CP113187 Location: 1..103507 Organism: Klebsiella pneumoniae strain SYCC2 Replicon: plasmid pSYCC2_mcr-8_103k
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OT482_RS01495 (OT482_01495) | 1742..2416 | + | 675 | WP_118860660.1 | SOS response-associated peptidase | - |
| OT482_RS01500 (OT482_01500) | 2713..3708 | + | 996 | WP_118860659.1 | hypothetical protein | - |
| OT482_RS01505 (OT482_01505) | 3780..4103 | + | 324 | WP_118860658.1 | hypothetical protein | - |
| OT482_RS01510 (OT482_01510) | 4350..5318 | + | 969 | WP_172691958.1 | IS5 family transposase IS903B | Transposase |
| OT482_RS01515 (OT482_01515) | 5589..6221 | + | 633 | WP_001567369.1 | hypothetical protein | - |
| OT482_RS01520 (OT482_01520) | 6250..7653 | - | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| OT482_RS01525 (OT482_01525) | 7958..8071 | + | 114 | Protein_7 | phosphoenolpyruvate hydrolase family protein | - |
| OT482_RS01530 (OT482_01530) | 8083..9456 | + | 1374 | WP_117252078.1 | serine hydrolase domain-containing protein | - |
| OT482_RS01535 (OT482_01535) | 9743..10213 | - | 471 | WP_072310984.1 | GyrI-like domain-containing protein | - |
| OT482_RS01540 (OT482_01540) | 10811..11617 | + | 807 | WP_072310988.1 | MipA/OmpV family protein | - |
| OT482_RS01545 (OT482_01545) | 11626..12717 | + | 1092 | WP_223349403.1 | serine hydrolase domain-containing protein | - |
| OT482_RS01550 (OT482_01550) | 12737..13093 | + | 357 | WP_072310983.1 | hypothetical protein | - |
| OT482_RS01555 (OT482_01555) | 13117..13650 | + | 534 | WP_072310982.1 | hypothetical protein | - |
| OT482_RS01560 (OT482_01560) | 13652..13861 | + | 210 | WP_072310981.1 | helix-turn-helix transcriptional regulator | - |
| OT482_RS01565 (OT482_01565) | 14059..14958 | + | 900 | WP_118842312.1 | hypothetical protein | VF |
| OT482_RS01570 (OT482_01570) | 15406..15795 | - | 390 | WP_118842310.1 | diacylglycerol kinase | - |
| OT482_RS01575 (OT482_01575) | 15909..17138 | - | 1230 | WP_072310978.1 | HAMP domain-containing sensor histidine kinase | - |
| OT482_RS01580 (OT482_01580) | 17160..17855 | - | 696 | WP_072310977.1 | Transcriptional activator protein CopR | VF |
| OT482_RS01585 (OT482_01585) | 17955..19652 | + | 1698 | WP_114699275.1 | phosphoethanolamine--lipid A transferase MCR-8.1 | VF |
| OT482_RS01590 (OT482_01590) | 19759..20649 | + | 891 | WP_118842309.1 | hypothetical protein | VF |
| OT482_RS01595 (OT482_01595) | 20894..21403 | + | 510 | WP_032445709.1 | GNAT family N-acetyltransferase | - |
| OT482_RS01600 (OT482_01600) | 22342..23040 | - | 699 | WP_032445707.1 | DJ-1/PfpI family protein | - |
| OT482_RS01605 (OT482_01605) | 23330..23680 | - | 351 | WP_223349401.1 | hypothetical protein | - |
| OT482_RS01610 (OT482_01610) | 23737..23940 | - | 204 | WP_072010199.1 | hemolysin expression modulator Hha | - |
| OT482_RS01615 (OT482_01615) | 24012..24980 | + | 969 | WP_075211999.1 | IS5 family transposase IS903 | Transposase |
| OT482_RS01620 (OT482_01620) | 25452..26243 | - | 792 | WP_221928726.1 | ribbon-helix-helix domain-containing protein | - |
| OT482_RS01625 (OT482_01625) | 26426..27454 | - | 1029 | WP_032445668.1 | Abi family protein | - |
| OT482_RS01630 (OT482_01630) | 27615..28196 | - | 582 | WP_072310991.1 | hypothetical protein | - |
| OT482_RS01635 (OT482_01635) | 28765..28983 | + | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| OT482_RS01640 (OT482_01640) | 28985..29290 | + | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| OT482_RS01645 (OT482_01645) | 29459..29854 | + | 396 | WP_017899885.1 | hypothetical protein | - |
| OT482_RS01650 (OT482_01650) | 29881..30204 | + | 324 | WP_004197641.1 | hypothetical protein | - |
| OT482_RS01655 (OT482_01655) | 30201..31217 | + | 1017 | WP_118842534.1 | hypothetical protein | - |
| OT482_RS01660 (OT482_01660) | 31415..32200 | + | 786 | WP_046664219.1 | site-specific integrase | - |
| OT482_RS01665 (OT482_01665) | 32649..33404 | + | 756 | WP_001568031.1 | replication initiation protein RepE | - |
| OT482_RS01670 (OT482_01670) | 34389..35021 | + | 633 | WP_017901447.1 | ParA family protein | - |
| OT482_RS01675 (OT482_01675) | 35021..35395 | + | 375 | WP_017901448.1 | hypothetical protein | - |
| OT482_RS01680 (OT482_01680) | 35635..36609 | + | 975 | WP_020801689.1 | plasmid segregation protein ParM | - |
| OT482_RS01685 (OT482_01685) | 36613..37005 | + | 393 | WP_046664218.1 | plasmid partitioning/stability family protein | - |
| OT482_RS01690 (OT482_01690) | 37575..37796 | - | 222 | WP_046664217.1 | helix-turn-helix domain-containing protein | - |
| OT482_RS01695 (OT482_01695) | 37827..38273 | - | 447 | WP_046664216.1 | hypothetical protein | - |
| OT482_RS01700 (OT482_01700) | 38544..38849 | - | 306 | WP_172691974.1 | hypothetical protein | - |
| OT482_RS01705 (OT482_01705) | 38903..39154 | - | 252 | WP_047368872.1 | plasmid stabilization protein | - |
| OT482_RS01710 (OT482_01710) | 39233..40504 | - | 1272 | WP_004206782.1 | Y-family DNA polymerase | - |
| OT482_RS01715 (OT482_01715) | 40504..40929 | - | 426 | WP_009309980.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| OT482_RS01720 (OT482_01720) | 41332..42819 | + | 1488 | WP_161952885.1 | hypothetical protein | VF |
| OT482_RS01725 (OT482_01725) | 43053..43283 | + | 231 | WP_004206779.1 | hypothetical protein | - |
| OT482_RS01730 (OT482_01730) | 43804..44229 | + | 426 | WP_186920192.1 | antirestriction protein | - |
| OT482_RS01735 (OT482_01735) | 44465..44719 | + | 255 | WP_049139361.1 | DNA polymerase III subunit theta | - |
| OT482_RS01740 (OT482_01740) | 44754..45071 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| OT482_RS01745 (OT482_01745) | 45853..46080 | + | 228 | WP_020803451.1 | hypothetical protein | - |
| OT482_RS01750 (OT482_01750) | 46172..46402 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| OT482_RS01755 (OT482_01755) | 46454..47809 | + | 1356 | WP_046664187.1 | DUF3560 domain-containing protein | - |
| OT482_RS01760 (OT482_01760) | 47857..48420 | + | 564 | WP_004152756.1 | methyltransferase | - |
| OT482_RS01765 (OT482_01765) | 49251..49793 | + | 543 | WP_073558210.1 | single-stranded DNA-binding protein | - |
| OT482_RS01770 (OT482_01770) | 49842..50090 | + | 249 | WP_032431380.1 | DUF905 domain-containing protein | - |
| OT482_RS01775 (OT482_01775) | 50160..52217 | + | 2058 | WP_117092697.1 | ParB/RepB/Spo0J family partition protein | - |
| OT482_RS01780 (OT482_01780) | 52262..52693 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| OT482_RS01785 (OT482_01785) | 52690..53418 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| OT482_RS01790 (OT482_01790) | 53415..53741 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| OT482_RS01795 (OT482_01795) | 53797..54171 | + | 375 | WP_023287106.1 | hypothetical protein | - |
| OT482_RS01800 (OT482_01800) | 54349..55428 | - | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| OT482_RS01805 (OT482_01805) | 55500..55661 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| OT482_RS01810 (OT482_01810) | 56360..56632 | + | 273 | WP_032445785.1 | hypothetical protein | - |
| OT482_RS01815 (OT482_01815) | 56629..56979 | + | 351 | WP_032445787.1 | hypothetical protein | - |
| OT482_RS01820 (OT482_01820) | 56994..57311 | + | 318 | WP_032445789.1 | hypothetical protein | - |
| OT482_RS01825 (OT482_01825) | 58151..58507 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| OT482_RS01830 (OT482_01830) | 58568..58780 | + | 213 | WP_032445756.1 | hypothetical protein | - |
| OT482_RS01835 (OT482_01835) | 58791..59015 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| OT482_RS01840 (OT482_01840) | 59096..59416 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| OT482_RS01845 (OT482_01845) | 59406..59684 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| OT482_RS01850 (OT482_01850) | 59685..60098 | + | 414 | WP_013023817.1 | helix-turn-helix domain-containing protein | - |
| OT482_RS01855 (OT482_01855) | 60816..61196 | + | 381 | WP_020802391.1 | hypothetical protein | - |
| OT482_RS01860 (OT482_01860) | 61263..61610 | + | 348 | WP_032445771.1 | hypothetical protein | - |
| OT482_RS01865 (OT482_01865) | 61705..61851 | + | 147 | WP_004152750.1 | hypothetical protein | - |
| OT482_RS01870 (OT482_01870) | 61902..62735 | + | 834 | WP_032445769.1 | N-6 DNA methylase | - |
| OT482_RS01875 (OT482_01875) | 63551..64372 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| OT482_RS01880 (OT482_01880) | 64405..64734 | + | 330 | WP_011977736.1 | DUF5983 family protein | - |
| OT482_RS01885 (OT482_01885) | 64767..65252 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| OT482_RS01890 (OT482_01890) | 65643..66059 | + | 417 | WP_072145360.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| OT482_RS01895 (OT482_01895) | 66259..66978 | + | 720 | WP_172691949.1 | conjugal transfer protein TrbJ | - |
| OT482_RS01900 (OT482_01900) | 67111..67314 | + | 204 | WP_171486139.1 | TraY domain-containing protein | - |
| OT482_RS01905 (OT482_01905) | 67379..67747 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| OT482_RS01910 (OT482_01910) | 67761..68066 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| OT482_RS01915 (OT482_01915) | 68086..68652 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| OT482_RS01920 (OT482_01920) | 68639..69379 | + | 741 | WP_172691947.1 | type-F conjugative transfer system secretin TraK | - |
| OT482_RS01925 (OT482_01925) | 69379..70803 | + | 1425 | WP_185775340.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| OT482_RS01930 (OT482_01930) | 70876..71460 | + | 585 | WP_040120377.1 | type IV conjugative transfer system lipoprotein TraV | - |
| OT482_RS01935 (OT482_01935) | 71783..72001 | + | 219 | WP_004171484.1 | hypothetical protein | - |
| OT482_RS01940 (OT482_01940) | 72002..72319 | + | 318 | WP_114473059.1 | hypothetical protein | - |
| OT482_RS01945 (OT482_01945) | 72386..72790 | + | 405 | WP_100748549.1 | hypothetical protein | - |
| OT482_RS01950 (OT482_01950) | 72815..73213 | + | 399 | WP_167875005.1 | hypothetical protein | - |
| OT482_RS01955 (OT482_01955) | 73285..75924 | + | 2640 | WP_150388098.1 | type IV secretion system protein TraC | - |
| OT482_RS01960 (OT482_01960) | 75924..76313 | + | 390 | WP_013214025.1 | type-F conjugative transfer system protein TrbI | - |
| OT482_RS01965 (OT482_01965) | 76313..76948 | + | 636 | WP_020325113.1 | type-F conjugative transfer system protein TraW | - |
| OT482_RS01970 (OT482_01970) | 76983..77384 | + | 402 | WP_004194979.1 | hypothetical protein | - |
| OT482_RS01975 (OT482_01975) | 77381..78370 | + | 990 | WP_032441886.1 | conjugal transfer pilus assembly protein TraU | - |
| OT482_RS01980 (OT482_01980) | 78383..79021 | + | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| OT482_RS01985 (OT482_01985) | 79080..81035 | + | 1956 | WP_172691973.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| OT482_RS01990 (OT482_01990) | 81067..81303 | + | 237 | WP_114499720.1 | conjugal transfer protein TrbE | - |
| OT482_RS01995 (OT482_01995) | 81531..81857 | + | 327 | WP_016529362.1 | hypothetical protein | - |
| OT482_RS02000 (OT482_02000) | 81878..82630 | + | 753 | WP_172691972.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| OT482_RS02005 (OT482_02005) | 82641..82880 | + | 240 | WP_009309875.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| OT482_RS02010 (OT482_02010) | 82852..83409 | + | 558 | WP_172691971.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| OT482_RS02015 (OT482_02015) | 83456..83902 | + | 447 | WP_172691970.1 | conjugal transfer protein TrbF | - |
| OT482_RS02020 (OT482_02020) | 83892..85259 | + | 1368 | WP_185775342.1 | conjugal transfer pilus assembly protein TraH | - |
| OT482_RS02025 (OT482_02025) | 85259..88108 | + | 2850 | WP_172691976.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| OT482_RS02030 (OT482_02030) | 88114..88641 | + | 528 | WP_040120388.1 | conjugal transfer protein TraS | - |
| OT482_RS02035 (OT482_02035) | 88830..89561 | + | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| OT482_RS02040 (OT482_02040) | 89754..90443 | + | 690 | WP_172691968.1 | hypothetical protein | - |
| OT482_RS02045 (OT482_02045) | 90570..92882 | + | 2313 | WP_228303505.1 | type IV conjugative transfer system coupling protein TraD | - |
| OT482_RS02050 (OT482_02050) | 92882..98140 | + | 5259 | WP_267689852.1 | Multifunctional conjugation protein TraI | Relaxase |
| OT482_RS02055 (OT482_02055) | 98221..98946 | + | 726 | WP_013023834.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| OT482_RS02060 (OT482_02060) | 99018..99611 | + | 594 | WP_013609537.1 | fertility inhibition protein FinO | - |
| OT482_RS02065 (OT482_02065) | 99772..100374 | + | 603 | WP_013023836.1 | PIN domain-containing protein | - |
| OT482_RS02070 (OT482_02070) | 100424..101068 | + | 645 | WP_172691960.1 | hypothetical protein | - |
| OT482_RS02075 (OT482_02075) | 101124..101774 | + | 651 | WP_172691975.1 | DUF2726 domain-containing protein | - |
| OT482_RS02080 (OT482_02080) | 101771..102079 | + | 309 | Protein_118 | hypothetical protein | - |
| OT482_RS02085 (OT482_02085) | 102183..102734 | + | 552 | WP_015065550.1 | Cardiolipin synthase A | VF |
| OT482_RS02090 (OT482_02090) | 102870..103139 | + | 270 | WP_022631531.1 | replication regulatory protein RepA | - |
| OT482_RS02095 (OT482_02095) | 103351..103428 | + | 78 | WP_020802013.1 | RepA leader peptide Tap | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|