MGE detailed information
MGE type: Conjugative plasmid MGE length: 104215 bp
Accession: NZ_CP113167 Location: 1..104215 Organism: Klebsiella pneumoniae strain TSNTC10-1 Replicon: plasmid pTSNTC10-1_mcr-8_104
Accession: NZ_CP113167 Location: 1..104215 Organism: Klebsiella pneumoniae strain TSNTC10-1 Replicon: plasmid pTSNTC10-1_mcr-8_104
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OT484_RS27995 (OT484_27995) | 416..1306 | + | 891 | WP_118842309.1 | hypothetical protein | VF |
| OT484_RS28000 (OT484_28000) | 1551..2060 | + | 510 | WP_032445709.1 | GNAT family N-acetyltransferase | - |
| OT484_RS28005 (OT484_28005) | 2999..3697 | - | 699 | WP_032445707.1 | DJ-1/PfpI family protein | - |
| OT484_RS28010 (OT484_28010) | 3987..4337 | - | 351 | WP_223349401.1 | hypothetical protein | - |
| OT484_RS28015 (OT484_28015) | 4394..4597 | - | 204 | WP_072010199.1 | hemolysin expression modulator Hha | - |
| OT484_RS28020 (OT484_28020) | 4669..5637 | + | 969 | WP_075211999.1 | IS5 family transposase IS903 | Transposase |
| OT484_RS28025 (OT484_28025) | 6109..6900 | - | 792 | WP_221928726.1 | ribbon-helix-helix domain-containing protein | - |
| OT484_RS28030 (OT484_28030) | 7083..8111 | - | 1029 | WP_032445668.1 | Abi family protein | - |
| OT484_RS28035 (OT484_28035) | 8272..8853 | - | 582 | WP_072310991.1 | hypothetical protein | - |
| OT484_RS28040 (OT484_28040) | 9422..9640 | + | 219 | WP_006788213.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| OT484_RS28045 (OT484_28045) | 9642..9947 | + | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| OT484_RS28050 (OT484_28050) | 10116..10511 | + | 396 | WP_017899885.1 | hypothetical protein | - |
| OT484_RS28055 (OT484_28055) | 10538..10861 | + | 324 | WP_004197641.1 | hypothetical protein | - |
| OT484_RS28060 (OT484_28060) | 10858..11874 | + | 1017 | WP_118842534.1 | hypothetical protein | - |
| OT484_RS28065 (OT484_28065) | 12072..12857 | + | 786 | WP_046664219.1 | site-specific integrase | - |
| OT484_RS28070 (OT484_28070) | 13306..14061 | + | 756 | WP_001568031.1 | replication initiation protein RepE | - |
| OT484_RS28075 (OT484_28075) | 15046..15678 | + | 633 | WP_017901447.1 | ParA family protein | - |
| OT484_RS28080 (OT484_28080) | 15678..16052 | + | 375 | WP_017901448.1 | hypothetical protein | - |
| OT484_RS28085 (OT484_28085) | 16292..17266 | + | 975 | WP_020801689.1 | plasmid segregation protein ParM | - |
| OT484_RS28090 (OT484_28090) | 17270..17662 | + | 393 | WP_046664218.1 | plasmid partitioning/stability family protein | - |
| OT484_RS28095 (OT484_28095) | 18232..18453 | - | 222 | WP_046664217.1 | helix-turn-helix domain-containing protein | - |
| OT484_RS28100 (OT484_28100) | 18484..18930 | - | 447 | WP_046664216.1 | hypothetical protein | - |
| OT484_RS28105 (OT484_28105) | 19201..19506 | - | 306 | WP_046664215.1 | hypothetical protein | - |
| OT484_RS28110 (OT484_28110) | 19560..19811 | - | 252 | WP_004206783.1 | plasmid stabilization protein | - |
| OT484_RS28115 (OT484_28115) | 19890..21161 | - | 1272 | WP_073558207.1 | Y-family DNA polymerase | - |
| OT484_RS28120 (OT484_28120) | 21161..21586 | - | 426 | WP_001776124.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| OT484_RS28125 (OT484_28125) | 21976..23238 | + | 1263 | WP_267695990.1 | IS1380 family transposase ISEcp1 | Transposase |
| OT484_RS28130 (OT484_28130) | 23494..24369 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| OT484_RS28135 (OT484_28135) | 24416..24760 | - | 345 | Protein_29 | WbuC family cupin fold metalloprotein | - |
| OT484_RS28140 (OT484_28140) | 24987..26474 | + | 1488 | WP_023332914.1 | hypothetical protein | VF |
| OT484_RS28145 (OT484_28145) | 26708..26938 | + | 231 | WP_004118481.1 | hypothetical protein | - |
| OT484_RS28150 (OT484_28150) | 27459..27884 | + | 426 | WP_032456807.1 | antirestriction protein | - |
| OT484_RS28155 (OT484_28155) | 28120..28374 | + | 255 | WP_049139361.1 | DNA polymerase III subunit theta | - |
| OT484_RS28160 (OT484_28160) | 28409..28726 | + | 318 | WP_267695991.1 | hypothetical protein | - |
| OT484_RS28165 (OT484_28165) | 29508..29735 | + | 228 | WP_020803451.1 | hypothetical protein | - |
| OT484_RS28170 (OT484_28170) | 29827..30057 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| OT484_RS28175 (OT484_28175) | 30109..31464 | + | 1356 | WP_118860665.1 | DUF3560 domain-containing protein | - |
| OT484_RS28180 (OT484_28180) | 31512..32075 | + | 564 | WP_004152756.1 | methyltransferase | - |
| OT484_RS28185 (OT484_28185) | 32905..33447 | + | 543 | WP_023280871.1 | single-stranded DNA-binding protein | - |
| OT484_RS28190 (OT484_28190) | 33496..33744 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| OT484_RS28195 (OT484_28195) | 33814..35871 | + | 2058 | WP_117092697.1 | ParB/RepB/Spo0J family partition protein | - |
| OT484_RS28200 (OT484_28200) | 35916..36347 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| OT484_RS28205 (OT484_28205) | 36344..37072 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| OT484_RS28210 (OT484_28210) | 37069..37395 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| OT484_RS28215 (OT484_28215) | 37451..37825 | + | 375 | WP_023287106.1 | hypothetical protein | - |
| OT484_RS28220 (OT484_28220) | 38003..39082 | - | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| OT484_RS28225 (OT484_28225) | 39154..39315 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| OT484_RS28230 (OT484_28230) | 40014..40286 | + | 273 | WP_212733081.1 | hypothetical protein | - |
| OT484_RS28235 (OT484_28235) | 40283..40633 | + | 351 | WP_032445787.1 | hypothetical protein | - |
| OT484_RS28240 (OT484_28240) | 40648..40965 | + | 318 | WP_032445789.1 | hypothetical protein | - |
| OT484_RS28245 (OT484_28245) | 41805..42161 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| OT484_RS28250 (OT484_28250) | 42222..42434 | + | 213 | WP_032445756.1 | hypothetical protein | - |
| OT484_RS28255 (OT484_28255) | 42445..42669 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| OT484_RS28260 (OT484_28260) | 42750..43070 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| OT484_RS28265 (OT484_28265) | 43060..43338 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| OT484_RS28270 (OT484_28270) | 43339..43752 | + | 414 | WP_013023817.1 | helix-turn-helix domain-containing protein | - |
| OT484_RS28275 (OT484_28275) | 44470..44850 | + | 381 | WP_020802391.1 | hypothetical protein | - |
| OT484_RS28280 (OT484_28280) | 44917..45264 | + | 348 | WP_032445771.1 | hypothetical protein | - |
| OT484_RS28285 (OT484_28285) | 45359..45505 | + | 147 | WP_004152750.1 | hypothetical protein | - |
| OT484_RS28290 (OT484_28290) | 45556..46389 | + | 834 | WP_032445769.1 | N-6 DNA methylase | - |
| OT484_RS28295 (OT484_28295) | 47205..48026 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| OT484_RS28300 (OT484_28300) | 48059..48388 | + | 330 | WP_011977736.1 | DUF5983 family protein | - |
| OT484_RS28305 (OT484_28305) | 48421..48906 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| OT484_RS28310 (OT484_28310) | 49297..49713 | + | 417 | WP_072145360.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| OT484_RS28315 (OT484_28315) | 49913..50632 | + | 720 | WP_172691949.1 | conjugal transfer protein TrbJ | - |
| OT484_RS28320 (OT484_28320) | 50765..50968 | + | 204 | WP_171486139.1 | TraY domain-containing protein | - |
| OT484_RS28325 (OT484_28325) | 51033..51401 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| OT484_RS28330 (OT484_28330) | 51415..51720 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| OT484_RS28335 (OT484_28335) | 51740..52306 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| OT484_RS28340 (OT484_28340) | 52293..53033 | + | 741 | WP_172691947.1 | type-F conjugative transfer system secretin TraK | - |
| OT484_RS28345 (OT484_28345) | 53033..54457 | + | 1425 | WP_185775340.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| OT484_RS28350 (OT484_28350) | 54530..55114 | + | 585 | WP_040120377.1 | type IV conjugative transfer system lipoprotein TraV | - |
| OT484_RS28355 (OT484_28355) | 55437..55655 | + | 219 | WP_004171484.1 | hypothetical protein | - |
| OT484_RS28360 (OT484_28360) | 55656..55973 | + | 318 | WP_114473059.1 | hypothetical protein | - |
| OT484_RS28365 (OT484_28365) | 56040..56444 | + | 405 | WP_100748549.1 | hypothetical protein | - |
| OT484_RS28370 (OT484_28370) | 56469..56867 | + | 399 | WP_167875005.1 | hypothetical protein | - |
| OT484_RS28375 (OT484_28375) | 56939..59578 | + | 2640 | WP_150388098.1 | type IV secretion system protein TraC | - |
| OT484_RS28380 (OT484_28380) | 59578..59967 | + | 390 | WP_013214025.1 | type-F conjugative transfer system protein TrbI | - |
| OT484_RS28385 (OT484_28385) | 59967..60602 | + | 636 | WP_020325113.1 | type-F conjugative transfer system protein TraW | - |
| OT484_RS28390 (OT484_28390) | 60637..61038 | + | 402 | WP_004194979.1 | hypothetical protein | - |
| OT484_RS28395 (OT484_28395) | 61035..62024 | + | 990 | WP_032441886.1 | conjugal transfer pilus assembly protein TraU | - |
| OT484_RS28400 (OT484_28400) | 62037..62675 | + | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| OT484_RS28405 (OT484_28405) | 62734..64689 | + | 1956 | WP_172691973.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| OT484_RS28410 (OT484_28410) | 64721..64957 | + | 237 | WP_114499720.1 | conjugal transfer protein TrbE | - |
| OT484_RS28415 (OT484_28415) | 65185..65511 | + | 327 | WP_016529362.1 | hypothetical protein | - |
| OT484_RS28420 (OT484_28420) | 65532..66284 | + | 753 | WP_212733076.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| OT484_RS28425 (OT484_28425) | 66295..66534 | + | 240 | WP_009309875.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| OT484_RS28430 (OT484_28430) | 66506..67063 | + | 558 | WP_172691971.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| OT484_RS28435 (OT484_28435) | 67110..67556 | + | 447 | WP_172691970.1 | conjugal transfer protein TrbF | - |
| OT484_RS28440 (OT484_28440) | 67546..68913 | + | 1368 | WP_267695988.1 | conjugal transfer pilus assembly protein TraH | - |
| OT484_RS28445 (OT484_28445) | 68913..71762 | + | 2850 | WP_267695989.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| OT484_RS28450 (OT484_28450) | 71768..72295 | + | 528 | WP_040120388.1 | conjugal transfer protein TraS | - |
| OT484_RS28455 (OT484_28455) | 72484..73215 | + | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| OT484_RS28460 (OT484_28460) | 73408..74097 | + | 690 | WP_172691968.1 | hypothetical protein | - |
| OT484_RS28465 (OT484_28465) | 74224..76536 | + | 2313 | WP_228303505.1 | type IV conjugative transfer system coupling protein TraD | - |
| OT484_RS28470 (OT484_28470) | 76536..81794 | + | 5259 | WP_172691966.1 | Multifunctional conjugation protein TraI | Relaxase |
| OT484_RS28475 (OT484_28475) | 81874..82599 | + | 726 | WP_015065543.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| OT484_RS28480 (OT484_28480) | 82671..83264 | + | 594 | WP_172691964.1 | fertility inhibition protein FinO | - |
| OT484_RS28485 (OT484_28485) | 83425..84027 | + | 603 | WP_172691962.1 | PIN domain-containing protein | - |
| OT484_RS28490 (OT484_28490) | 84077..84721 | + | 645 | WP_172691960.1 | hypothetical protein | - |
| OT484_RS28495 (OT484_28495) | 84777..85427 | + | 651 | WP_172691975.1 | DUF2726 domain-containing protein | - |
| OT484_RS28500 (OT484_28500) | 85424..85732 | + | 309 | Protein_102 | hypothetical protein | - |
| OT484_RS28505 (OT484_28505) | 85836..86387 | + | 552 | WP_015065550.1 | Cardiolipin synthase A | VF |
| OT484_RS28510 (OT484_28510) | 86523..86792 | + | 270 | WP_022631531.1 | replication regulatory protein RepA | - |
| OT484_RS28515 (OT484_28515) | 87004..87081 | + | 78 | WP_020802013.1 | RepA leader peptide Tap | - |
| OT484_RS28520 (OT484_28520) | 87074..87937 | + | 864 | WP_087796302.1 | incFII family plasmid replication initiator RepA | - |
| OT484_RS28525 (OT484_28525) | 88902..89576 | + | 675 | WP_118860660.1 | SOS response-associated peptidase | - |
| OT484_RS28530 (OT484_28530) | 89873..90868 | + | 996 | WP_118860659.1 | hypothetical protein | - |
| OT484_RS28535 (OT484_28535) | 90940..91263 | + | 324 | WP_118860658.1 | hypothetical protein | - |
| OT484_RS28540 (OT484_28540) | 91510..92478 | + | 969 | WP_172691958.1 | IS5 family transposase IS903B | Transposase |
| OT484_RS28545 (OT484_28545) | 92835..92948 | + | 114 | Protein_111 | phosphoenolpyruvate hydrolase family protein | - |
| OT484_RS28550 (OT484_28550) | 92969..94333 | + | 1365 | WP_158192059.1 | serine hydrolase domain-containing protein | - |
| OT484_RS28555 (OT484_28555) | 94620..95090 | - | 471 | WP_072310984.1 | GyrI-like domain-containing protein | - |
| OT484_RS28560 (OT484_28560) | 95688..96494 | + | 807 | WP_072310988.1 | MipA/OmpV family protein | - |
| OT484_RS28565 (OT484_28565) | 96503..97594 | + | 1092 | WP_223349403.1 | serine hydrolase domain-containing protein | - |
| OT484_RS28570 (OT484_28570) | 97614..97970 | + | 357 | WP_072310983.1 | hypothetical protein | - |
| OT484_RS28575 (OT484_28575) | 97994..98527 | + | 534 | WP_072310982.1 | hypothetical protein | - |
| OT484_RS28580 (OT484_28580) | 98529..98738 | + | 210 | WP_072310981.1 | helix-turn-helix transcriptional regulator | - |
| OT484_RS28585 (OT484_28585) | 98936..99835 | + | 900 | WP_118842312.1 | hypothetical protein | VF |
| OT484_RS28590 (OT484_28590) | 100283..100672 | - | 390 | WP_118842310.1 | diacylglycerol kinase | - |
| OT484_RS28595 (OT484_28595) | 100786..102015 | - | 1230 | WP_072310978.1 | HAMP domain-containing sensor histidine kinase | - |
| OT484_RS28600 (OT484_28600) | 102037..102732 | - | 696 | WP_072310977.1 | Transcriptional activator protein CopR | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|