NZ_CP1099751..162625

MGE detailed information

MGE type: Mobilizable plasmid        MGE length: 162625 bp
Accession: NZ_CP109975        Location: 1..162625         Organism: Klebsiella pneumoniae strain 857       Replicon: plasmid pB


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI501_RS27930 (1) 1..858 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
OI501_RS27935 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
OI501_RS27940 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
OI501_RS27945 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
OI501_RS27950 (3383) 3383..3798 + 416 Protein_4 IS1-like element IS1B family transposase -
OI501_RS27955 (3834) 3834..4379 - 546 Protein_5 Tn3 family transposase TnpA_Tn3 Transposase
OI501_RS27960 (4445) 4445..5149 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS27965 (5219) 5219..5410 + 192 Protein_7 IS1380 family transposase -
OI501_RS27970 (5660) 5660..6535 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
OI501_RS27975 (6570) 6570..7538 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
OI501_RS27980 (7595) 7595..8692 + 1098 Protein_10 TonB-dependent receptor -
OI501_RS27985 (8760) 8760..9236 - 477 Protein_11 PAS domain-containing protein -
OI501_RS27990 (9289) 9289..9993 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS27995 (10058) 10058..10648 + 591 Protein_13 IS91 family transposase ISSbo1 Transposase
OI501_RS28000 (11104) 11104..11808 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28005 (11859) 11859..12476 - 618 Protein_15 IS91 family transposase ISSbo1 Transposase
OI501_RS28010 (12486) 12486..12674 - 189 WP_000957857.1 hypothetical protein -
OI501_RS28015 (12766) 12766..13302 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
OI501_RS28020 (13485) 13485..14345 + 861 WP_000027057.1 Beta-lactamase TEM ARG
OI501_RS28025 (14515) 14515..15270 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
OI501_RS28030 (15351) 15351..15665 - 315 Protein_20 hypothetical protein -
OI501_RS28035 (15720) 15720..16424 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28040 (16490) 16490..16555 + 66 Protein_22 IS1 family transposase -
OI501_RS28045 (18004) 18004..18238 + 235 Protein_23 type II toxin-antitoxin system RelE/ParE family toxin -
OI501_RS28050 (18366) 18366..18647 + 282 WP_001333089.1 hypothetical protein -
OI501_RS28055 (18770) 18770..19120 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
OI501_RS28060 (19123) 19123..20085 - 963 WP_000959884.1 plasmid segregation protein ParM -
OI501_RS28065 (20232) 20232..20525 + 294 WP_032146011.1 hypothetical protein -
OI501_RS28070 (20602) 20602..21285 + 684 WP_000085883.1 DNA methylase -
OI501_RS28075 (21286) 21286..21507 + 222 WP_001104881.1 hypothetical protein -
OI501_RS28080 (21521) 21521..21955 + 435 WP_000274503.1 DUF1380 family protein -
OI501_RS28085 (22006) 22006..22782 + 777 WP_001383963.1 hypothetical protein -
OI501_RS28090 (23200) 23200..23625 + 426 WP_001198928.1 antirestriction protein -
OI501_RS28095 (23672) 23672..24094 + 423 WP_000271762.1 DUF1380 family protein -
OI501_RS28100 (24091) 24091..24282 + 192 WP_001027493.1 hypothetical protein -
OI501_RS28105 (24596) 24596..26263 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
OI501_RS28110 (26992) 26992..27146 - 155 Protein_36 hypothetical protein -
OI501_RS28115 (27663) 27663..27893 + 231 WP_000218642.1 hypothetical protein -
OI501_RS28120 (27945) 27945..29306 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
OI501_RS28125 (29353) 29353..29916 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
OI501_RS28130 (30002) 30002..30457 - 456 Protein_40 hypothetical protein -
OI501_RS28135 (30759) 30759..31286 + 528 WP_000290834.1 single-stranded DNA-binding protein -
OI501_RS28140 (31344) 31344..31577 + 234 WP_000006003.1 DUF905 family protein -
OI501_RS28145 (31638) 31638..33661 + 2024 Protein_43 ParB/RepB/Spo0J family partition protein -
OI501_RS28150 (33730) 33730..34164 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
OI501_RS28155 (34161) 34161..34880 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (34892) 34892..35116 + 225 NuclAT_0 - Antitoxin Detail
- (34892) 34892..35116 + 225 NuclAT_0 - Antitoxin Detail
- (34892) 34892..35116 + 225 NuclAT_0 - Antitoxin Detail
- (34892) 34892..35116 + 225 NuclAT_0 - Antitoxin Detail
OI501_RS28160 (35102) 35102..35251 + 150 Protein_46 plasmid maintenance protein Mok -
OI501_RS28165 (35193) 35193..35318 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
OI501_RS28170 (35637) 35637..35933 - 297 Protein_48 hypothetical protein -
OI501_RS28175 (36233) 36233..36529 + 297 WP_001272251.1 hypothetical protein -
OI501_RS28180 (36640) 36640..37461 + 822 WP_001234445.1 DUF932 domain-containing protein -
OI501_RS28185 (37758) 37758..38405 - 648 WP_015059008.1 hypothetical protein VF
OI501_RS28190 (38682) 38682..39065 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
OI501_RS28195 (39346) 39346..40050 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28200 (40104) 40104..40427 - 324 Protein_54 class II aldolase/adducin family protein -
OI501_RS28205 (40420) 40420..41672 - 1253 Protein_55 four-carbon acid sugar kinase family protein -
OI501_RS28210 (41684) 41684..42586 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
OI501_RS28215 (42848) 42848..43609 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
OI501_RS28220 (43630) 43630..44490 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
OI501_RS28225 (44627) 44627..44695 + 69 Protein_59 IS6 family transposase -
OI501_RS28230 (44731) 44731..46482 - 1752 Protein_60 Tn3 family transposase TnpA_TnAs1 Transposase
OI501_RS28235 (46486) 46486..46878 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
OI501_RS28240 (47016) 47016..47900 + 885 WP_000058717.1 EamA family transporter -
OI501_RS28245 (47932) 47932..49131 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
OI501_RS28250 (49237) 49237..49887 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
OI501_RS28255 (50065) 50065..50133 + 69 Protein_65 IS6 family transposase -
OI501_RS28260 (50169) 50169..51920 - 1752 Protein_66 Tn3 family transposase TnpA_TnAs1 Transposase
OI501_RS28265 (51924) 51924..52316 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
OI501_RS28270 (52454) 52454..53338 + 885 WP_000058717.1 EamA family transporter -
OI501_RS28275 (53370) 53370..54569 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
OI501_RS28280 (54675) 54675..55325 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
OI501_RS28285 (55503) 55503..55571 + 69 Protein_71 IS6 family transposase -
OI501_RS28290 (55607) 55607..57358 - 1752 Protein_72 Tn3 family transposase TnpA_TnAs1 Transposase
OI501_RS28295 (57362) 57362..57754 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
OI501_RS28300 (57892) 57892..58776 + 885 WP_000058717.1 EamA family transporter -
OI501_RS28305 (58808) 58808..60007 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
OI501_RS28310 (60113) 60113..60763 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
OI501_RS28315 (60941) 60941..61009 + 69 Protein_77 IS6 family transposase -
OI501_RS28320 (61045) 61045..62796 - 1752 Protein_78 Tn3 family transposase TnpA_TnAs1 Transposase
OI501_RS28325 (62800) 62800..63192 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
OI501_RS28330 (63330) 63330..64214 + 885 WP_000058717.1 EamA family transporter -
OI501_RS28335 (64246) 64246..65445 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
OI501_RS28340 (65551) 65551..66201 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
OI501_RS28345 (66379) 66379..66447 + 69 Protein_83 IS6 family transposase -
OI501_RS28350 (66483) 66483..68234 - 1752 Protein_84 Tn3 family transposase TnpA_TnAs1 Transposase
OI501_RS28355 (68238) 68238..68630 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
OI501_RS28360 (68768) 68768..69652 + 885 WP_000058717.1 EamA family transporter -
OI501_RS28365 (69684) 69684..70883 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
OI501_RS28370 (70989) 70989..71639 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
OI501_RS28375 (71817) 71817..72521 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28380 (72665) 72665..73306 - 642 WP_001011939.1 Chloramphenicol acetyltransferase 2 ARG
OI501_RS28385 (73456) 73456..73872 - 417 WP_227642713.1 hypothetical protein -
OI501_RS28390 (74036) 74036..74740 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28395 (74746) 74746..74886 + 141 WP_001044210.1 hypothetical protein -
OI501_RS28400 (75372) 75372..76109 + 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
OI501_RS28405 (76106) 76106..76330 + 225 WP_000743213.1 hypothetical protein -
OI501_RS28410 (76541) 76541..78034 + 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
OI501_RS28415 (78270) 78270..78512 - 243 Protein_97 phosphoglucosamine mutase -
OI501_RS28420 (78599) 78599..79414 - 816 WP_001043260.1 Dihydropteroate synthase ARG
OI501_RS28425 (79744) 79744..79830 + 87 Protein_99 Arm DNA-binding domain-containing protein -
OI501_RS28430 (80102) 80102..81106 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
OI501_RS28435 (81185) 81185..82951 - 1767 Protein_101 Tn3 family transposase TnpA_ISPa38 Transposase
OI501_RS28440 (83003) 83003..83707 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28445 (83772) 83772..84944 - 1173 Protein_103 transposase -
OI501_RS28450 (85019) 85019..85687 - 669 WP_001300294.1 putative signaling protein VF
OI501_RS28455 (85723) 85723..85959 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
OI501_RS28460 (85956) 85956..86318 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
OI501_RS28465 (86336) 86336..88030 - 1695 WP_000105636.1 mercury(II) reductase -
OI501_RS28470 (88082) 88082..88504 - 423 WP_001340589.1 organomercurial transporter MerC -
OI501_RS28475 (88540) 88540..88815 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
OI501_RS28480 (88829) 88829..89179 - 351 WP_001294663.1 mercuric transport protein MerT -
OI501_RS28485 (89251) 89251..89685 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
OI501_RS28490 (89764) 89764..90768 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
OI501_RS28495 (91296) 91296..92696 - 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
OI501_RS28500 (92693) 92693..93373 - 681 WP_001188930.1 Transcriptional activator protein CopR VF
OI501_RS28505 (93428) 93428..94357 - 930 WP_004213583.1 copper resistance inner membrane protein PcoD -
OI501_RS28510 (94362) 94362..94742 - 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
OI501_RS28515 (94782) 94782..95672 - 891 WP_029884201.1 copper resistance outer membrane transporter PcoB -
OI501_RS28520 (95678) 95678..97495 - 1818 WP_004213580.1 multicopper oxidase PcoA -
OI501_RS28525 (97729) 97729..98196 + 468 WP_048336866.1 hypothetical protein -
OI501_RS28530 (98463) 98463..99200 + 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
OI501_RS28535 (99234) 99234..99431 - 198 WP_000843497.1 DUF2933 domain-containing protein -
OI501_RS28540 (99472) 99472..101919 - 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
OI501_RS28545 (102046) 102046..102486 - 441 WP_000758228.1 DUF411 domain-containing protein -
OI501_RS28550 (102573) 102573..105719 - 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
OI501_RS28555 (105730) 105730..107022 - 1293 WP_004213579.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
OI501_RS28560 (107136) 107136..107498 - 363 WP_004213578.1 cation efflux system protein CusF -
OI501_RS28565 (107527) 107527..108912 - 1386 WP_004213577.1 Cation efflux system protein CusC VF
OI501_RS28570 (109102) 109102..109782 + 681 WP_004213574.1 Transcriptional regulatory protein CusR VF
OI501_RS28575 (109775) 109775..111250 + 1476 WP_000555737.1 copper/silver sensor histidine kinase SilS -
OI501_RS28580 (111501) 111501..111932 + 432 WP_023302802.1 silver-binding protein SilE -
OI501_RS28585 (112076) 112076..112426 + 351 WP_004213569.1 DUF305 domain-containing protein -
OI501_RS28590 (112813) 112813..113721 - 909 WP_023302803.1 HNH endonuclease -
OI501_RS28595 (114358) 114358..115332 + 975 WP_004213565.1 sensor domain-containing diguanylate cyclase -
OI501_RS28600 (115511) 115511..115756 + 246 Protein_134 hypothetical protein -
OI501_RS28605 (115917) 115917..116861 + 945 WP_011977810.1 hypothetical protein -
OI501_RS28610 (116898) 116898..117290 + 393 WP_011977811.1 hypothetical protein -
OI501_RS28615 (117348) 117348..117869 + 522 WP_013214008.1 hypothetical protein -
OI501_RS28620 (117915) 117915..118118 + 204 WP_011977813.1 hypothetical protein -
OI501_RS28625 (118148) 118148..119152 + 1005 WP_011977814.1 hypothetical protein -
OI501_RS28630 (119336) 119336..120115 + 780 WP_013214009.1 site-specific integrase -
OI501_RS28635 (120161) 120161..120418 - 258 WP_013214010.1 hypothetical protein -
OI501_RS28640 (120547) 120547..120660 - 114 WP_014343462.1 hypothetical protein -
OI501_RS28645 (121196) 121196..122062 + 867 WP_004118283.1 replication initiation protein -
OI501_RS28650 (123172) 123172..124377 + 1206 WP_011977818.1 AAA family ATPase -
OI501_RS28655 (124377) 124377..125351 + 975 WP_011977819.1 ParB family protein -
OI501_RS28660 (125433) 125433..126704 - 1272 WP_013214011.1 Y-family DNA polymerase -
OI501_RS28665 (126704) 126704..127135 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
OI501_RS28670 (127542) 127542..129029 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
OI501_RS28675 (129278) 129278..130249 + 972 WP_004152353.1 plasmid segregation protein ParM -
OI501_RS28680 (130252) 130252..130923 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
OI501_RS28685 (130986) 130986..131216 + 231 WP_001568040.1 hypothetical protein -
OI501_RS28690 (131412) 131412..131581 + 170 Protein_152 hypothetical protein -
OI501_RS28695 (131653) 131653..132354 + 702 WP_001568041.1 DNA methylase -
OI501_RS28700 (132354) 132354..132575 + 222 WP_001568042.1 hypothetical protein -
OI501_RS28705 (132585) 132585..133004 + 420 WP_001568043.1 DUF1380 domain-containing protein -
OI501_RS28710 (133058) 133058..133825 + 768 WP_013214013.1 hypothetical protein -
OI501_RS28715 (134506) 134506..134934 + 429 WP_001568045.1 antirestriction protein -
OI501_RS28720 (134977) 134977..135483 + 507 WP_013214014.1 antirestriction protein ArdA -
OI501_RS28725 (135526) 135526..135717 + 192 WP_001568047.1 hypothetical protein -
OI501_RS28730 (135905) 135905..136159 + 255 WP_011977779.1 DNA polymerase III subunit theta -
OI501_RS28735 (136194) 136194..136514 + 321 WP_001568049.1 hypothetical protein -
OI501_RS28740 (137194) 137194..137421 + 228 WP_001568050.1 hypothetical protein -
OI501_RS28745 (137513) 137513..137743 + 231 WP_001568051.1 hypothetical protein -
OI501_RS28750 (137795) 137795..139150 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
OI501_RS28755 (139198) 139198..139761 + 564 WP_014343514.1 methyltransferase -
OI501_RS28760 (140594) 140594..141136 + 543 WP_014343512.1 single-stranded DNA-binding protein -
OI501_RS28765 (141185) 141185..141433 + 249 WP_001568055.1 DUF905 domain-containing protein -
OI501_RS28770 (141503) 141503..143560 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
OI501_RS28775 (143605) 143605..144036 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
OI501_RS28780 (144033) 144033..144761 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
OI501_RS28785 (144758) 144758..145084 + 327 WP_013023807.1 hypothetical protein -
OI501_RS28790 (145140) 145140..145514 + 375 WP_014343510.1 hypothetical protein -
OI501_RS28795 (145698) 145698..146771 - 1074 WP_013609528.1 IS481 family transposase ISKpn28 Transposase
OI501_RS28800 (146885) 146885..147001 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
OI501_RS28805 (147694) 147694..147966 + 273 WP_040245921.1 hypothetical protein -
OI501_RS28810 (147963) 147963..148313 + 351 WP_040245917.1 hypothetical protein -
OI501_RS28815 (148328) 148328..148645 + 318 WP_014343505.1 hypothetical protein -
OI501_RS28820 (149486) 149486..149842 + 357 WP_014343501.1 hypothetical protein -
OI501_RS28825 (149903) 149903..150115 + 213 WP_014343500.1 hypothetical protein -
OI501_RS28830 (150126) 150126..150350 + 225 WP_014343499.1 hypothetical protein -
OI501_RS28835 (150431) 150431..150751 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
OI501_RS28840 (150741) 150741..151019 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
OI501_RS28845 (151023) 151023..151127 + 105 Protein_183 transcriptional regulator -
OI501_RS28850 (151956) 151956..152777 + 822 WP_004152492.1 DUF932 domain-containing protein -
OI501_RS28855 (152810) 152810..153139 + 330 WP_013214015.1 DUF5983 family protein -
OI501_RS28860 (153172) 153172..153657 - 486 WP_014343495.1 hypothetical protein VF
OI501_RS28865 (154048) 154048..154464 + 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
OI501_RS28870 (154664) 154664..155401 + 738 WP_154244330.1 conjugal transfer protein TrbJ -
OI501_RS28875 (155516) 155516..155722 + 207 WP_171773970.1 TraY domain-containing protein -
OI501_RS28880 (155784) 155784..156152 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
OI501_RS28885 (156166) 156166..156471 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
OI501_RS28890 (156491) 156491..156856 + 366 Protein_192 type IV conjugative transfer system protein TraE -
OI501_RS28895 (156911) 156911..157255 - 345 Protein_193 IS6 family transposase IS26 Transposase
OI501_RS28900 (157307) 157307..158011 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
OI501_RS28905 (158036) 158036..158236 + 201 WP_072354025.1 hypothetical protein -
OI501_RS28910 (158256) 158256..159002 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
OI501_RS28915 (159057) 159057..159617 + 561 WP_000139328.1 fertility inhibition protein FinO -
OI501_RS28920 (159749) 159749..159949 + 201 WP_015059022.1 hypothetical protein -
OI501_RS28925 (160335) 160335..160934 + 600 WP_032083981.1 PIN domain-containing protein -
OI501_RS28930 (160996) 160996..161328 + 333 WP_152916585.1 hypothetical protein -
- (161529) 161529..161588 - 60 NuclAT_1 - Antitoxin Detail
- (161529) 161529..161588 - 60 NuclAT_1 - Antitoxin Detail
- (161529) 161529..161588 - 60 NuclAT_1 - Antitoxin Detail
- (161529) 161529..161588 - 60 NuclAT_1 - Antitoxin Detail
OI501_RS28935 (161633) 161633..161782 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
OI501_RS28940 (162066) 162066..162314 + 249 WP_000083837.1 replication regulatory protein RepA -
OI501_RS28945 (162429) 162429..162613 + 185 Protein_203 protein CopA/IncA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance