MGE detailed information
MGE type: Conjugative plasmid MGE length: 112409 bp
Accession: NZ_CP104680 Location: 1..112409 Organism: Klebsiella pneumoniae strain 2021CK-00608 Replicon: plasmid unnamed2
Accession: NZ_CP104680 Location: 1..112409 Organism: Klebsiella pneumoniae strain 2021CK-00608 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N5933_RS27525 (N5933_27530) | 1..1014 | + | 1014 | WP_040120366.1 | plasmid replication initiator RepA | - |
| N5933_RS27530 (N5933_27535) | 1988..2314 | - | 327 | WP_004201125.1 | C2H2-type zinc finger protein | - |
| N5933_RS27535 (N5933_27540) | 2496..2777 | + | 282 | WP_001568067.1 | hypothetical protein | - |
| N5933_RS27540 (N5933_27545) | 2831..3442 | + | 612 | WP_000176305.1 | DUF2913 family protein | - |
| N5933_RS27545 (N5933_27550) | 3439..3549 | - | 111 | Protein_4 | hypothetical protein | - |
| N5933_RS27550 (N5933_27555) | 3591..4295 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| N5933_RS27555 (N5933_27560) | 4359..4688 | + | 330 | WP_004201171.1 | divalent-cation tolerance protein CutA | - |
| N5933_RS27560 (N5933_27565) | 4693..5067 | + | 375 | Protein_7 | protein-disulfide reductase DsbD family protein | - |
| N5933_RS27565 (N5933_27570) | 5167..5724 | + | 558 | Protein_8 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| N5933_RS27570 (N5933_27575) | 5735..6373 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| N5933_RS27575 (N5933_27580) | 6378..6743 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| N5933_RS27580 (N5933_27585) | 6747..7559 | - | 813 | WP_004201164.1 | Metallo-beta-lactamase type 2 | ARG |
| N5933_RS27585 (N5933_27590) | 7774..8805 | - | 1032 | WP_071905678.1 | IS630 family transposase ISSpu2 | Transposase |
| N5933_RS27590 (N5933_27595) | 8905..9783 | - | 879 | Protein_13 | IS30 family transposase ISAba125 | Transposase |
| N5933_RS27595 (N5933_27600) | 9992..10771 | - | 780 | WP_014386410.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| N5933_RS27600 (N5933_27605) | 10877..11047 | - | 171 | Protein_15 | integrase core domain-containing protein | - |
| N5933_RS27605 (N5933_27610) | 11187..11732 | + | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| N5933_RS27610 (N5933_27615) | 11869..12441 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| N5933_RS27615 (N5933_27620) | 12478..13869 | + | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| N5933_RS27620 (N5933_27625) | 13902..14330 | + | 429 | Protein_19 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| N5933_RS27625 (N5933_27630) | 14649..15305 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| N5933_RS27630 (N5933_27635) | 15700..16715 | + | 1016 | Protein_21 | IS3 family transposase ISEc36 | Transposase |
| N5933_RS27635 (N5933_27640) | 16758..19541 | - | 2784 | Protein_22 | Tn3 family transposase TnpA_Tn3 | Transposase |
| N5933_RS27640 (N5933_27645) | 19555..19899 | + | 345 | Protein_23 | WbuC family cupin fold metalloprotein | - |
| N5933_RS27645 (N5933_27650) | 19946..20821 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| N5933_RS27650 (N5933_27655) | 21077..22339 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| N5933_RS27655 (N5933_27660) | 22521..22739 | - | 219 | WP_001143771.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| N5933_RS27660 (N5933_27665) | 22903..23460 | + | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| N5933_RS27665 (N5933_27670) | 23694..24248 | + | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| N5933_RS27670 (N5933_27675) | 24318..25106 | + | 789 | WP_001206315.1 | Streptomycin 3''-adenylyltransferase | ARG |
| N5933_RS27675 (N5933_27680) | 25166..25990 | + | 825 | Protein_30 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| N5933_RS27680 (N5933_27685) | 26190..26507 | + | 318 | Protein_31 | Tn3 family transposase TnpR_Tn3 | Transposase |
| N5933_RS27685 (N5933_27690) | 26690..27436 | + | 747 | Protein_32 | Beta-lactamase TEM | ARG |
| N5933_RS27695 (N5933_27700) | 28205..28894 | - | 690 | Protein_34 | ATP-binding protein | - |
| N5933_RS27700 (N5933_27705) | 28968..29384 | - | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| N5933_RS27705 (N5933_27710) | 29381..29611 | - | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| N5933_RS27710 (N5933_27715) | 29568..30027 | + | 460 | Protein_37 | hypothetical protein | - |
| N5933_RS27715 (N5933_27720) | 30514..30822 | + | 309 | WP_004152336.1 | hypothetical protein | - |
| N5933_RS27720 (N5933_27725) | 30850..31179 | + | 330 | WP_004152337.1 | hypothetical protein | - |
| N5933_RS27725 (N5933_27730) | 31205..31603 | + | 399 | WP_004171440.1 | hypothetical protein | - |
| N5933_RS27730 (N5933_27735) | 31610..31942 | + | 333 | WP_004152339.1 | hypothetical protein | - |
| N5933_RS27735 (N5933_27740) | 31942..32724 | + | 783 | WP_004152340.1 | site-specific integrase | - |
| N5933_RS27740 (N5933_27745) | 33938..34411 | - | 474 | WP_004152341.1 | YkgJ family cysteine cluster protein | - |
| N5933_RS27745 (N5933_27750) | 34531..35799 | - | 1269 | WP_004152342.1 | ISL3 family transposase ISKpn25 | Transposase |
| N5933_RS27750 (N5933_27755) | 35804..39061 | - | 3258 | WP_004152343.1 | DEAD/DEAH box helicase family protein | - |
| N5933_RS27755 (N5933_27760) | 39062..40378 | - | 1317 | WP_004152344.1 | restriction endonuclease subunit S | - |
| N5933_RS27760 (N5933_27765) | 40375..42402 | - | 2028 | WP_004152345.1 | class I SAM-dependent DNA methyltransferase | - |
| N5933_RS27765 (N5933_27770) | 42514..42729 | - | 216 | WP_004227314.1 | hypothetical protein | - |
| N5933_RS27770 (N5933_27775) | 42954..43286 | - | 333 | WP_004152347.1 | hypothetical protein | - |
| N5933_RS27775 (N5933_27780) | 43663..44637 | - | 975 | WP_004152348.1 | ParB family protein | - |
| N5933_RS27780 (N5933_27785) | 44634..45839 | - | 1206 | WP_004152349.1 | Plasmid partition protein A | VF |
| N5933_RS27785 (N5933_27790) | 46161..47057 | - | 897 | WP_004152350.1 | RepB family plasmid replication initiator protein | - |
| N5933_RS27790 (N5933_27795) | 47458..48729 | - | 1272 | WP_004152351.1 | Y-family DNA polymerase | - |
| N5933_RS27795 (N5933_27800) | 48729..49160 | - | 432 | WP_004152352.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| N5933_RS27800 (N5933_27805) | 49392..50363 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| N5933_RS27805 (N5933_27810) | 50366..51037 | + | 672 | WP_004152354.1 | plasmid partitioning/stability family protein | - |
| N5933_RS27810 (N5933_27815) | 51098..51328 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| N5933_RS27815 (N5933_27820) | 51524..51693 | + | 170 | Protein_58 | hypothetical protein | - |
| N5933_RS27820 (N5933_27825) | 51765..52466 | + | 702 | WP_001568041.1 | DNA methylase | - |
| N5933_RS27825 (N5933_27830) | 52466..52687 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| N5933_RS27830 (N5933_27835) | 52697..53116 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| N5933_RS27835 (N5933_27840) | 53170..53937 | + | 768 | WP_032445745.1 | hypothetical protein | - |
| N5933_RS27840 (N5933_27845) | 54570..54998 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| N5933_RS27845 (N5933_27850) | 55041..55547 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| N5933_RS27850 (N5933_27855) | 55590..55781 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| N5933_RS27855 (N5933_27860) | 55969..56223 | + | 255 | WP_032445741.1 | DNA polymerase III subunit theta | - |
| N5933_RS27860 (N5933_27865) | 56258..56575 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| N5933_RS27865 (N5933_27870) | 57371..57913 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| N5933_RS27870 (N5933_27875) | 57962..58210 | + | 249 | WP_032445658.1 | DUF905 domain-containing protein | - |
| N5933_RS27875 (N5933_27880) | 58280..60337 | + | 2058 | WP_040120383.1 | ParB/RepB/Spo0J family partition protein | - |
| N5933_RS27880 (N5933_27885) | 60382..60813 | + | 432 | WP_004194235.1 | conjugation system SOS inhibitor PsiB | - |
| N5933_RS27885 (N5933_27890) | 60810..61538 | + | 729 | WP_015065618.1 | plasmid SOS inhibition protein A | - |
| N5933_RS27890 (N5933_27895) | 61535..61861 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| N5933_RS27895 (N5933_27900) | 61917..62291 | + | 375 | WP_040120382.1 | hypothetical protein | - |
| N5933_RS27900 (N5933_27905) | 62495..63864 | + | 1370 | WP_085949440.1 | IS3 family transposase ISKpn8 | Transposase |
| N5933_RS27905 (N5933_27910) | 63908..64057 | + | 150 | Protein_76 | FlmC family protein | - |
| N5933_RS27910 (N5933_27915) | 64008..64124 | + | 117 | WP_055313929.1 | type I toxin-antitoxin system Hok family toxin | - |
| N5933_RS27915 (N5933_27920) | 64823..65095 | + | 273 | WP_032445785.1 | hypothetical protein | - |
| N5933_RS27920 (N5933_27925) | 65092..65442 | + | 351 | WP_032445787.1 | hypothetical protein | - |
| N5933_RS27925 (N5933_27930) | 65457..65774 | + | 318 | WP_032445789.1 | hypothetical protein | - |
| N5933_RS27930 (N5933_27935) | 66615..66971 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| N5933_RS27935 (N5933_27940) | 67032..67244 | + | 213 | WP_032445756.1 | hypothetical protein | - |
| N5933_RS27940 (N5933_27945) | 67255..67479 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| N5933_RS27945 (N5933_27950) | 67560..67880 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| N5933_RS27950 (N5933_27955) | 67870..68148 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| N5933_RS27955 (N5933_27960) | 68149..68562 | + | 414 | WP_040120381.1 | helix-turn-helix domain-containing protein | - |
| N5933_RS27960 (N5933_27965) | 69280..69660 | + | 381 | WP_020802391.1 | hypothetical protein | - |
| N5933_RS27965 (N5933_27970) | 69727..70074 | + | 348 | WP_032445771.1 | hypothetical protein | - |
| N5933_RS27970 (N5933_27975) | 70169..70315 | + | 147 | WP_004152750.1 | hypothetical protein | - |
| N5933_RS27975 (N5933_27980) | 70366..71199 | + | 834 | WP_032445769.1 | N-6 DNA methylase | - |
| N5933_RS27980 (N5933_27985) | 72016..72837 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| N5933_RS27985 (N5933_27990) | 72870..73199 | + | 330 | WP_011977736.1 | DUF5983 family protein | - |
| N5933_RS27990 (N5933_27995) | 73232..73717 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| N5933_RS27995 (N5933_28000) | 74149..74541 | + | 393 | WP_004194114.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| N5933_RS28000 (N5933_28005) | 74771..75472 | + | 702 | WP_040120380.1 | hypothetical protein | - |
| N5933_RS28005 (N5933_28010) | 75558..75758 | + | 201 | WP_046664192.1 | TraY domain-containing protein | - |
| N5933_RS28010 (N5933_28015) | 75826..76194 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| N5933_RS28015 (N5933_28020) | 76208..76513 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| N5933_RS28020 (N5933_28025) | 76533..77099 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| N5933_RS28025 (N5933_28030) | 77086..77826 | + | 741 | WP_040120379.1 | type-F conjugative transfer system secretin TraK | - |
| N5933_RS28030 (N5933_28035) | 77826..79250 | + | 1425 | WP_040120378.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| N5933_RS28035 (N5933_28040) | 79322..79906 | + | 585 | WP_040120377.1 | type IV conjugative transfer system lipoprotein TraV | - |
| N5933_RS28040 (N5933_28045) | 80229..80447 | + | 219 | WP_004195468.1 | hypothetical protein | - |
| N5933_RS28045 (N5933_28050) | 80448..80759 | + | 312 | WP_029497417.1 | hypothetical protein | - |
| N5933_RS28050 (N5933_28055) | 80826..81230 | + | 405 | WP_004197817.1 | hypothetical protein | - |
| N5933_RS28055 (N5933_28060) | 81273..81425 | + | 153 | WP_224518895.1 | hypothetical protein | - |
| N5933_RS28060 (N5933_28065) | 81607..82005 | + | 399 | WP_023179972.1 | hypothetical protein | - |
| N5933_RS28065 (N5933_28070) | 82077..84716 | + | 2640 | WP_013214024.1 | type IV secretion system protein TraC | - |
| N5933_RS28070 (N5933_28075) | 84716..85105 | + | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| N5933_RS28075 (N5933_28080) | 85105..85740 | + | 636 | WP_029497419.1 | type-F conjugative transfer system protein TraW | - |
| N5933_RS28080 (N5933_28085) | 85775..86176 | + | 402 | WP_040120376.1 | hypothetical protein | - |
| N5933_RS28085 (N5933_28090) | 86173..87162 | + | 990 | WP_029497420.1 | conjugal transfer pilus assembly protein TraU | - |
| N5933_RS28090 (N5933_28095) | 87175..87813 | + | 639 | WP_015065635.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| N5933_RS28095 (N5933_28100) | 87872..89827 | + | 1956 | WP_040120375.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| N5933_RS28100 (N5933_28105) | 89859..90113 | + | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| N5933_RS28105 (N5933_28110) | 90091..90339 | + | 249 | WP_004152675.1 | hypothetical protein | - |
| N5933_RS28110 (N5933_28115) | 90352..90678 | + | 327 | WP_004144402.1 | hypothetical protein | - |
| N5933_RS28115 (N5933_28120) | 90699..91451 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| N5933_RS28120 (N5933_28125) | 91462..91701 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| N5933_RS28125 (N5933_28130) | 91673..92230 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| N5933_RS28130 (N5933_28135) | 92276..92719 | + | 444 | WP_014343488.1 | F-type conjugal transfer protein TrbF | - |
| N5933_RS28135 (N5933_28140) | 92697..94076 | + | 1380 | WP_072198320.1 | conjugal transfer pilus assembly protein TraH | - |
| N5933_RS28140 (N5933_28145) | 94076..96925 | + | 2850 | WP_040120373.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| N5933_RS28145 (N5933_28150) | 96931..97458 | + | 528 | WP_040120388.1 | conjugal transfer protein TraS | - |
| N5933_RS28150 (N5933_28155) | 97647..98378 | + | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| N5933_RS28155 (N5933_28160) | 98571..99260 | + | 690 | WP_072198322.1 | hypothetical protein | - |
| N5933_RS28160 (N5933_28165) | 99389..101701 | + | 2313 | WP_040120372.1 | type IV conjugative transfer system coupling protein TraD | - |
| N5933_RS28165 (N5933_28170) | 101701..106962 | + | 5262 | WP_040120371.1 | Multifunctional conjugation protein TraI | Relaxase |
| N5933_RS28170 (N5933_28175) | 107042..107767 | + | 726 | WP_040120370.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| N5933_RS28175 (N5933_28180) | 107839..108432 | + | 594 | WP_004152380.1 | fertility inhibition protein FinO | - |
| N5933_RS28180 (N5933_28185) | 108593..109195 | + | 603 | WP_064750782.1 | PIN domain-containing protein | - |
| N5933_RS28185 (N5933_28190) | 109245..109889 | + | 645 | WP_004153014.1 | hypothetical protein | - |
| N5933_RS28190 (N5933_28195) | 109945..110595 | + | 651 | WP_040120368.1 | DUF2726 domain-containing protein | - |
| N5933_RS28195 (N5933_28200) | 110592..110900 | + | 309 | WP_040120367.1 | hypothetical protein | - |
| N5933_RS28200 (N5933_28205) | 111004..111555 | + | 552 | WP_013609507.1 | Phospholipase D | VF |
| N5933_RS28205 (N5933_28210) | 111673..111942 | + | 270 | WP_072198323.1 | replication regulatory protein RepA | - |
| N5933_RS28210 (N5933_28215) | 112174..112251 | + | 78 | WP_071905679.1 | RepA leader peptide Tap | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|