MGE detailed information
MGE type: Conjugative plasmid MGE length: 100197 bp
Accession: NZ_CP104079 Location: 1..100197 Organism: Escherichia coli strain HB42 Replicon: plasmid pHB42-2
Accession: NZ_CP104079 Location: 1..100197 Organism: Escherichia coli strain HB42 Replicon: plasmid pHB42-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N0M81_RS23340 (109) | 109..357 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| N0M81_RS23345 (472) | 472..650 | + | 179 | Protein_1 | protein CopA/IncA | - |
| N0M81_RS23350 (669) | 669..1526 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| N0M81_RS23355 (2227) | 2227..2367 | + | 141 | WP_173671011.1 | hypothetical protein | - |
| N0M81_RS23360 (2440) | 2440..2709 | + | 270 | WP_089438644.1 | type II toxin-antitoxin system antitoxin YacA | - |
| N0M81_RS23365 (2709) | 2709..2987 | + | 279 | Protein_5 | type II toxin-antitoxin system toxin YacB | - |
| N0M81_RS23370 (3033) | 3033..3713 | + | 681 | WP_226156984.1 | 3'-5' exonuclease | - |
| N0M81_RS23375 (3759) | 3759..4655 | - | 897 | WP_226156987.1 | hypothetical protein | - |
| N0M81_RS23380 (4797) | 4797..5162 | - | 366 | WP_226156990.1 | hypothetical protein | - |
| N0M81_RS23385 (5477) | 5477..6664 | - | 1188 | WP_226156993.1 | IS91 family transposase ISEc37 | Transposase |
| N0M81_RS23390 (6664) | 6664..7029 | - | 366 | WP_226156997.1 | hypothetical protein | - |
| N0M81_RS23395 (7473) | 7473..8701 | + | 1229 | WP_162843061.1 | IS3 family transposase IS2 | Transposase |
| N0M81_RS23400 (8861) | 8861..13543 | + | 4683 | WP_226156943.1 | Outer membrane protein IcsA autotransporter | VF |
| N0M81_RS23405 (13956) | 13956..14267 | + | 312 | WP_259904982.1 | hypothetical protein | - |
| N0M81_RS23410 (14795) | 14795..18610 | + | 3816 | WP_226156939.1 | hypothetical protein | - |
| N0M81_RS23415 (18946) | 18946..19694 | + | 749 | Protein_15 | ISKra4 family transposase ISEc51 | Transposase |
| N0M81_RS23420 (20055) | 20055..20573 | - | 519 | WP_259904984.1 | DUF4238 domain-containing protein | - |
| N0M81_RS23425 (20880) | 20880..21164 | + | 285 | WP_075858633.1 | ribbon-helix-helix protein, CopG family | Antitoxin Detail |
| N0M81_RS23430 (21164) | 21164..21439 | + | 276 | WP_226156935.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| N0M81_RS23435 (21546) | 21546..21749 | + | 204 | Protein_19 | hypothetical protein | - |
| N0M81_RS23440 (22046) | 22046..22345 | + | 300 | WP_226156930.1 | hypothetical protein | - |
| N0M81_RS23450 (23174) | 23174..26140 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| N0M81_RS23455 (26144) | 26144..26704 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| N0M81_RS23460 (26880) | 26880..27230 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| N0M81_RS23465 (27433) | 27433..28446 | - | 1014 | WP_104774822.1 | IS91 family transposase ISAzo26 | Transposase |
| N0M81_RS23470 (28591) | 28591..29088 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| N0M81_RS23475 (29200) | 29200..29490 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| N0M81_RS23480 (29496) | 29496..30334 | + | 839 | Protein_28 | Streptomycin 3''-adenylyltransferase | ARG |
| N0M81_RS23485 (30451) | 30451..30798 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| N0M81_RS23490 (30792) | 30792..31124 | + | 333 | Protein_30 | IS6 family transposase IS15 | Transposase |
| N0M81_RS23495 (31181) | 31181..31884 | + | 704 | Protein_31 | IS6 family transposase IS26 | Transposase |
| N0M81_RS23500 (32013) | 32013..32777 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| N0M81_RS23505 (33270) | 33270..33854 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| N0M81_RS23510 (33854) | 33854..35091 | - | 1238 | Protein_34 | macrolide resistance MFS transporter Mrx(A) | - |
| N0M81_RS23515 (35088) | 35088..35993 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| N0M81_RS23520 (36115) | 36115..36819 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| N0M81_RS23525 (37130) | 37130..37687 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| N0M81_RS23530 (37870) | 37870..38730 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| N0M81_RS23535 (38900) | 38900..39655 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| N0M81_RS23540 (39781) | 39781..40485 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| N0M81_RS23545 (40535) | 40535..41278 | + | 744 | Protein_41 | Beta-lactamase TEM | ARG |
| N0M81_RS23550 (41536) | 41536..42012 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| N0M81_RS23555 (42059) | 42059..42934 | - | 876 | WP_015387340.1 | Beta-lactamase CTX-M-1 | ARG |
| N0M81_RS23560 (43356) | 43356..44060 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| N0M81_RS23565 (44126) | 44126..44191 | + | 66 | Protein_45 | IS1 family transposase | - |
| N0M81_RS23570 (45640) | 45640..45874 | + | 235 | Protein_46 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| N0M81_RS23575 (46002) | 46002..46205 | + | 204 | Protein_47 | hypothetical protein | - |
| N0M81_RS23580 (46406) | 46406..46756 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| N0M81_RS23585 (46759) | 46759..47721 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| N0M81_RS23590 (47868) | 47868..48161 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| N0M81_RS23595 (48238) | 48238..48921 | + | 684 | WP_000085883.1 | DNA methylase | - |
| N0M81_RS23600 (48922) | 48922..49143 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| N0M81_RS23605 (49157) | 49157..49591 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| N0M81_RS23610 (49642) | 49642..50418 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| N0M81_RS23615 (50836) | 50836..51261 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| N0M81_RS23620 (51308) | 51308..51730 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| N0M81_RS23625 (51727) | 51727..51918 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| N0M81_RS23630 (52956) | 52956..53186 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| N0M81_RS23635 (53238) | 53238..54599 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| N0M81_RS23640 (54645) | 54645..55208 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| N0M81_RS23645 (55294) | 55294..55755 | - | 462 | Protein_61 | hypothetical protein | - |
| N0M81_RS23650 (56057) | 56057..56584 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| N0M81_RS23655 (56642) | 56642..56875 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| N0M81_RS23660 (56936) | 56936..58904 | + | 1969 | Protein_64 | ParB/RepB/Spo0J family partition protein | - |
| N0M81_RS23665 (58973) | 58973..59407 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| N0M81_RS23670 (59404) | 59404..60166 | + | 763 | Protein_66 | plasmid SOS inhibition protein A | - |
| N0M81_RS23675 (60144) | 60144..60323 | - | 180 | WP_001309233.1 | hypothetical protein | - |
| - (60135) | 60135..60359 | + | 225 | NuclAT_0 | - | - |
| - (60135) | 60135..60359 | + | 225 | NuclAT_0 | - | - |
| - (60135) | 60135..60359 | + | 225 | NuclAT_0 | - | - |
| - (60135) | 60135..60359 | + | 225 | NuclAT_0 | - | - |
| N0M81_RS23680 (60345) | 60345..60494 | + | 150 | Protein_68 | plasmid maintenance protein Mok | - |
| N0M81_RS23685 (60436) | 60436..60561 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| N0M81_RS23690 (60880) | 60880..61176 | - | 297 | Protein_70 | hypothetical protein | - |
| N0M81_RS23695 (61476) | 61476..61772 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| N0M81_RS23700 (61883) | 61883..62704 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| N0M81_RS23705 (63001) | 63001..63648 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| N0M81_RS23710 (63925) | 63925..64308 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| N0M81_RS23715 (64499) | 64499..65185 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| N0M81_RS23720 (65279) | 65279..65506 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| N0M81_RS23725 (65540) | 65540..65905 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| N0M81_RS23730 (65920) | 65920..66231 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| N0M81_RS23735 (66253) | 66253..66818 | + | 566 | Protein_79 | type IV conjugative transfer system protein TraE | - |
| N0M81_RS23740 (66805) | 66805..67533 | + | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| N0M81_RS23745 (67533) | 67533..68961 | + | 1429 | Protein_81 | conjugal transfer protein TraB | - |
| N0M81_RS23750 (68951) | 68951..69541 | + | 591 | WP_000002778.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| N0M81_RS23755 (69528) | 69528..69725 | + | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| N0M81_RS23760 (69737) | 69737..69988 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| N0M81_RS23765 (69985) | 69985..70500 | + | 516 | WP_000809902.1 | type IV conjugative transfer system lipoprotein TraV | - |
| N0M81_RS23770 (70635) | 70635..70856 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| N0M81_RS23775 (71016) | 71016..73642 | + | 2627 | Protein_87 | type IV secretion system protein TraC | - |
| N0M81_RS23780 (73639) | 73639..74025 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| N0M81_RS23785 (74022) | 74022..74654 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| N0M81_RS23790 (74651) | 74651..75643 | + | 993 | WP_259904979.1 | conjugal transfer pilus assembly protein TraU | - |
| N0M81_RS23795 (75670) | 75670..75978 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| N0M81_RS23800 (76041) | 76041..76562 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| N0M81_RS23805 (76589) | 76589..77227 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| N0M81_RS23810 (77224) | 77224..77595 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| N0M81_RS23815 (77621) | 77621..78043 | + | 423 | WP_001229309.1 | HNH endonuclease signature motif containing protein | - |
| N0M81_RS23820 (78040) | 78040..79890 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| N0M81_RS23825 (79917) | 79917..80174 | + | 258 | WP_000864321.1 | conjugal transfer protein TrbE | - |
| N0M81_RS23830 (80167) | 80167..80910 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| N0M81_RS23835 (81071) | 81071..81307 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| N0M81_RS23840 (81294) | 81294..81839 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| N0M81_RS23845 (81829) | 81829..82143 | + | 315 | WP_001384255.1 | P-type conjugative transfer protein TrbJ | - |
| N0M81_RS23850 (82097) | 82097..82489 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| N0M81_RS23855 (82476) | 82476..83849 | + | 1374 | WP_000944325.1 | conjugal transfer pilus assembly protein TraH | - |
| N0M81_RS23860 (83846) | 83846..86662 | + | 2817 | WP_015059018.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| N0M81_RS23865 (86695) | 86695..87216 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| N0M81_RS23870 (87241) | 87241..87972 | + | 732 | WP_021559024.1 | conjugal transfer complement resistance protein TraT | - |
| N0M81_RS23875 (88175) | 88175..88912 | + | 738 | WP_015059020.1 | hypothetical protein | - |
| N0M81_RS23880 (88963) | 88963..91206 | + | 2244 | WP_072646483.1 | type IV conjugative transfer system coupling protein TraD | - |
| N0M81_RS23885 (91206) | 91206..96476 | + | 5271 | WP_061093447.1 | Multifunctional conjugation protein TraI | Relaxase |
| N0M81_RS23890 (96496) | 96496..97242 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| N0M81_RS23895 (97297) | 97297..97857 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| N0M81_RS23900 (97989) | 97989..98189 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| N0M81_RS23905 (98575) | 98575..99174 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| N0M81_RS23910 (99236) | 99236..99568 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (99769) | 99769..99828 | - | 60 | NuclAT_1 | - | - |
| - (99769) | 99769..99828 | - | 60 | NuclAT_1 | - | - |
| - (99769) | 99769..99828 | - | 60 | NuclAT_1 | - | - |
| - (99769) | 99769..99828 | - | 60 | NuclAT_1 | - | - |
| N0M81_RS23915 (99873) | 99873..100022 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|