MGE detailed information
MGE type: Conjugative plasmid MGE length: 114874 bp
Accession: NZ_CP103607 Location: 1..114874 Organism: Klebsiella pneumoniae strain 4386 Replicon: plasmid pMB7231_2
Accession: NZ_CP103607 Location: 1..114874 Organism: Klebsiella pneumoniae strain 4386 Replicon: plasmid pMB7231_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5S85_RS25965 (M5S85_25965) | 1..897 | + | 897 | WP_004152350.1 | RepB family plasmid replication initiator protein | - |
| M5S85_RS25970 (M5S85_25970) | 1219..2424 | + | 1206 | WP_004152349.1 | Plasmid partition protein A | VF |
| M5S85_RS25975 (M5S85_25975) | 2421..3395 | + | 975 | WP_004152348.1 | ParB family protein | - |
| M5S85_RS25980 (M5S85_25980) | 3772..4104 | + | 333 | WP_004152347.1 | hypothetical protein | - |
| M5S85_RS25985 (M5S85_25985) | 4329..4544 | + | 216 | WP_004227314.1 | hypothetical protein | - |
| M5S85_RS25990 (M5S85_25990) | 4656..6683 | + | 2028 | WP_004152345.1 | class I SAM-dependent DNA methyltransferase | - |
| M5S85_RS25995 (M5S85_25995) | 6680..7996 | + | 1317 | WP_004152344.1 | restriction endonuclease subunit S | - |
| M5S85_RS26000 (M5S85_26000) | 7997..11254 | + | 3258 | WP_004152343.1 | DEAD/DEAH box helicase family protein | - |
| M5S85_RS26005 (M5S85_26005) | 11259..12527 | + | 1269 | WP_004152342.1 | ISL3 family transposase ISKpn25 | Transposase |
| M5S85_RS26010 (M5S85_26010) | 12647..13120 | + | 474 | WP_004152341.1 | YkgJ family cysteine cluster protein | - |
| M5S85_RS26015 (M5S85_26015) | 13212..13442 | + | 231 | WP_011977773.1 | hypothetical protein | - |
| M5S85_RS26020 (M5S85_26020) | 14334..15116 | - | 783 | WP_004152340.1 | site-specific integrase | - |
| M5S85_RS26025 (M5S85_26025) | 15116..15448 | - | 333 | WP_004152339.1 | hypothetical protein | - |
| M5S85_RS26030 (M5S85_26030) | 15455..15853 | - | 399 | WP_004171440.1 | hypothetical protein | - |
| M5S85_RS26035 (M5S85_26035) | 15879..16208 | - | 330 | WP_004152337.1 | hypothetical protein | - |
| M5S85_RS26040 (M5S85_26040) | 16236..16544 | - | 309 | WP_004152336.1 | hypothetical protein | - |
| M5S85_RS26045 (M5S85_26045) | 17490..17720 | + | 231 | WP_032662167.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M5S85_RS26050 (M5S85_26050) | 17717..18127 | + | 411 | WP_032662169.1 | PIN domain-containing protein | Toxin Detail |
| M5S85_RS26055 (M5S85_26055) | 18201..18890 | + | 690 | Protein_18 | ATP-binding protein | - |
| M5S85_RS26060 (M5S85_26060) | 18945..19642 | + | 698 | WP_223174630.1 | IS1 family transposase ISKpn14 | Transposase |
| M5S85_RS26065 (M5S85_26065) | 19658..19768 | + | 111 | Protein_20 | mercuric transport protein periplasmic component | - |
| M5S85_RS26070 (M5S85_26070) | 19804..20226 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| M5S85_RS26075 (M5S85_26075) | 20278..21972 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| M5S85_RS26080 (M5S85_26080) | 21990..22352 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| M5S85_RS26085 (M5S85_26085) | 22349..22585 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| M5S85_RS26090 (M5S85_26090) | 22621..23289 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| M5S85_RS26095 (M5S85_26095) | 23364..24614 | + | 1251 | Protein_26 | transposase | - |
| M5S85_RS26100 (M5S85_26100) | 24679..25050 | + | 372 | Protein_27 | IS6 family transposase IS15DII | Transposase |
| M5S85_RS26105 (M5S85_26105) | 25200..26060 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M5S85_RS26110 (M5S85_26110) | 26243..26560 | - | 318 | Protein_29 | Tn3 family transposase TnpR_Tn3 | Transposase |
| M5S85_RS26115 (M5S85_26115) | 26760..27584 | - | 825 | Protein_30 | OXA-9 family oxacillin-hydrolyzing class D beta-lactamase | - |
| M5S85_RS26120 (M5S85_26120) | 27644..27754 | - | 111 | Protein_31 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| M5S85_RS26125 (M5S85_26125) | 27804..28508 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S85_RS26130 (M5S85_26130) | 28581..31478 | + | 2898 | WP_004152403.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| M5S85_RS26135 (M5S85_26135) | 31567..32187 | + | 621 | WP_004152402.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| M5S85_RS26140 (M5S85_26140) | 32286..32696 | + | 411 | WP_004152401.1 | hypothetical protein | - |
| M5S85_RS26145 (M5S85_26145) | 33353..33712 | - | 360 | WP_004152400.1 | DUF305 domain-containing protein | - |
| M5S85_RS26150 (M5S85_26150) | 33884..34114 | - | 231 | Protein_37 | IS5 family transposase ISAeme7 | Transposase |
| M5S85_RS26155 (M5S85_26155) | 34216..35400 | + | 1185 | WP_004152398.1 | ISAs1 family transposase ISKpn31 | Transposase |
| M5S85_RS26160 (M5S85_26160) | 35677..36996 | + | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| M5S85_RS26165 (M5S85_26165) | 37246..38127 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| M5S85_RS26170 (M5S85_26170) | 38415..39194 | - | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| M5S85_RS26175 (M5S85_26175) | 39191..40216 | - | 1026 | WP_004199214.1 | IS21 family transposase ISKpn7 | Transposase |
| M5S85_RS26180 (M5S85_26180) | 40323..43352 | - | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
| M5S85_RS26185 (M5S85_26185) | 43462..45177 | + | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| M5S85_RS26190 (M5S85_26190) | 45472..45627 | + | 156 | WP_001404092.1 | hypothetical protein | - |
| M5S85_RS26195 (M5S85_26195) | 45676..46668 | + | 993 | WP_001145103.1 | hypothetical protein | - |
| M5S85_RS26200 (M5S85_26200) | 46725..46856 | + | 132 | Protein_47 | ISNCY family transposase | - |
| M5S85_RS26205 (M5S85_26205) | 47065..47676 | - | 612 | WP_004152389.1 | DUF2913 family protein | - |
| M5S85_RS26210 (M5S85_26210) | 47660..48223 | - | 564 | WP_004152388.1 | ProQ/FINO family protein | - |
| M5S85_RS26215 (M5S85_26215) | 49442..50299 | - | 858 | WP_004152386.1 | incFII family plasmid replication initiator RepA | - |
| M5S85_RS26220 (M5S85_26220) | 50601..50870 | - | 270 | WP_013609506.1 | replication regulatory protein RepA | - |
| M5S85_RS26225 (M5S85_26225) | 50988..51539 | - | 552 | WP_004152384.1 | Cardiolipin synthase A | VF |
| M5S85_RS26230 (M5S85_26230) | 51643..51951 | - | 309 | WP_004152383.1 | hypothetical protein | - |
| M5S85_RS26235 (M5S85_26235) | 51948..52598 | - | 651 | WP_004152382.1 | DUF2726 domain-containing protein | - |
| M5S85_RS26240 (M5S85_26240) | 52654..53298 | - | 645 | WP_004153014.1 | hypothetical protein | - |
| M5S85_RS26245 (M5S85_26245) | 53348..53950 | - | 603 | WP_015060010.1 | PIN domain-containing protein | - |
| M5S85_RS26250 (M5S85_26250) | 54111..54704 | - | 594 | WP_004152380.1 | fertility inhibition protein FinO | - |
| M5S85_RS26255 (M5S85_26255) | 54776..55501 | - | 726 | WP_004152379.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| M5S85_RS26260 (M5S85_26260) | 55582..60843 | - | 5262 | WP_004153015.1 | Multifunctional conjugation protein TraI | Relaxase |
| M5S85_RS26265 (M5S85_26265) | 60843..63155 | - | 2313 | WP_004152620.1 | type IV conjugative transfer system coupling protein TraD | - |
| M5S85_RS26270 (M5S85_26270) | 63284..63973 | - | 690 | WP_004198206.1 | hypothetical protein | - |
| M5S85_RS26275 (M5S85_26275) | 64165..64896 | - | 732 | WP_004152622.1 | conjugal transfer complement resistance protein TraT | - |
| M5S85_RS26280 (M5S85_26280) | 65080..65628 | - | 549 | WP_004152623.1 | conjugal transfer entry exclusion protein TraS | - |
| M5S85_RS26285 (M5S85_26285) | 65641..68490 | - | 2850 | WP_004152624.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M5S85_RS26290 (M5S85_26290) | 68490..69869 | - | 1380 | WP_004165169.1 | conjugal transfer pilus assembly protein TraH | - |
| M5S85_RS26295 (M5S85_26295) | 69847..70290 | - | 444 | WP_004152679.1 | F-type conjugal transfer protein TrbF | - |
| M5S85_RS26300 (M5S85_26300) | 70336..70893 | - | 558 | WP_004152678.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M5S85_RS26305 (M5S85_26305) | 70865..71104 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M5S85_RS26310 (M5S85_26310) | 71115..71867 | - | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| M5S85_RS26315 (M5S85_26315) | 71888..72214 | - | 327 | WP_004152676.1 | hypothetical protein | - |
| M5S85_RS26320 (M5S85_26320) | 72227..72475 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| M5S85_RS26325 (M5S85_26325) | 72453..72707 | - | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| M5S85_RS26330 (M5S85_26330) | 72739..74694 | - | 1956 | WP_004152673.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| M5S85_RS26335 (M5S85_26335) | 74753..75391 | - | 639 | WP_004152672.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| M5S85_RS26340 (M5S85_26340) | 75404..76393 | - | 990 | WP_011977785.1 | conjugal transfer pilus assembly protein TraU | - |
| M5S85_RS26345 (M5S85_26345) | 76390..76779 | - | 390 | WP_004152508.1 | hypothetical protein | - |
| M5S85_RS26350 (M5S85_26350) | 76821..77447 | - | 627 | WP_004152507.1 | type-F conjugative transfer system protein TraW | - |
| M5S85_RS26355 (M5S85_26355) | 77447..77836 | - | 390 | WP_004152506.1 | type-F conjugative transfer system protein TrbI | - |
| M5S85_RS26360 (M5S85_26360) | 77836..80475 | - | 2640 | WP_004152505.1 | type IV secretion system protein TraC | - |
| M5S85_RS26365 (M5S85_26365) | 80547..80945 | - | 399 | WP_011977783.1 | hypothetical protein | - |
| M5S85_RS26370 (M5S85_26370) | 80953..81342 | - | 390 | WP_004153076.1 | hypothetical protein | - |
| M5S85_RS26375 (M5S85_26375) | 81385..81789 | - | 405 | WP_004152503.1 | hypothetical protein | - |
| M5S85_RS26380 (M5S85_26380) | 81856..82167 | - | 312 | WP_004152502.1 | hypothetical protein | - |
| M5S85_RS26385 (M5S85_26385) | 82168..82386 | - | 219 | WP_004152501.1 | hypothetical protein | - |
| M5S85_RS26390 (M5S85_26390) | 82492..82902 | - | 411 | WP_004152499.1 | hypothetical protein | - |
| M5S85_RS26395 (M5S85_26395) | 83034..83618 | - | 585 | WP_004161368.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M5S85_RS26400 (M5S85_26400) | 83732..85156 | - | 1425 | WP_004155033.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M5S85_RS26405 (M5S85_26405) | 85156..85896 | - | 741 | WP_004152497.1 | type-F conjugative transfer system secretin TraK | - |
| M5S85_RS26410 (M5S85_26410) | 85883..86449 | - | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| M5S85_RS26415 (M5S85_26415) | 86469..86774 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| M5S85_RS26420 (M5S85_26420) | 86788..87156 | - | 369 | WP_004152496.1 | type IV conjugative transfer system pilin TraA | - |
| M5S85_RS26425 (M5S85_26425) | 87210..87596 | - | 387 | WP_004152495.1 | TraY domain-containing protein | - |
| M5S85_RS26430 (M5S85_26430) | 87675..88361 | - | 687 | WP_004152494.1 | transcriptional regulator TraJ family protein | - |
| M5S85_RS26435 (M5S85_26435) | 88447..89427 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| M5S85_RS26440 (M5S85_26440) | 89735..90133 | - | 399 | WP_004152493.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M5S85_RS26445 (M5S85_26445) | 90555..91040 | + | 486 | WP_001568108.1 | hypothetical protein | VF |
| M5S85_RS26450 (M5S85_26450) | 91073..91402 | - | 330 | WP_011977736.1 | DUF5983 family protein | - |
| M5S85_RS26455 (M5S85_26455) | 91435..92256 | - | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| M5S85_RS26460 (M5S85_26460) | 93076..93909 | - | 834 | WP_004152751.1 | N-6 DNA methylase | - |
| M5S85_RS26465 (M5S85_26465) | 93960..94106 | - | 147 | WP_004152750.1 | hypothetical protein | - |
| M5S85_RS26470 (M5S85_26470) | 94201..94548 | - | 348 | WP_004152749.1 | hypothetical protein | - |
| M5S85_RS26475 (M5S85_26475) | 94605..94958 | - | 354 | WP_004152748.1 | hypothetical protein | - |
| M5S85_RS26480 (M5S85_26480) | 95588..95938 | - | 351 | WP_004153414.1 | hypothetical protein | - |
| M5S85_RS26485 (M5S85_26485) | 95935..96207 | - | 273 | WP_004152661.1 | hypothetical protein | - |
| M5S85_RS26490 (M5S85_26490) | 96255..96614 | - | 360 | WP_004152660.1 | hypothetical protein | - |
| M5S85_RS26495 (M5S85_26495) | 96725..97048 | - | 324 | WP_004199367.1 | hypothetical protein | - |
| M5S85_RS26500 (M5S85_26500) | 97052..97774 | - | 723 | WP_004152658.1 | plasmid SOS inhibition protein A | - |
| M5S85_RS26505 (M5S85_26505) | 97771..98202 | - | 432 | WP_004152657.1 | conjugation system SOS inhibitor PsiB | - |
| M5S85_RS26510 (M5S85_26510) | 98248..100257 | - | 2010 | WP_004152656.1 | ParB/RepB/Spo0J family partition protein | - |
| M5S85_RS26515 (M5S85_26515) | 100326..100568 | - | 243 | WP_004152655.1 | DUF905 domain-containing protein | - |
| M5S85_RS26520 (M5S85_26520) | 100616..101128 | - | 513 | WP_004152654.1 | single-stranded DNA-binding protein | - |
| M5S85_RS26525 (M5S85_26525) | 101959..102522 | - | 564 | WP_004152756.1 | methyltransferase | - |
| M5S85_RS26530 (M5S85_26530) | 102570..103925 | - | 1356 | WP_013054814.1 | DUF3560 domain-containing protein | - |
| M5S85_RS26535 (M5S85_26535) | 103977..104207 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| M5S85_RS26540 (M5S85_26540) | 104299..104526 | - | 228 | WP_004152790.1 | hypothetical protein | - |
| M5S85_RS26545 (M5S85_26545) | 105310..105627 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| M5S85_RS26550 (M5S85_26550) | 105662..105916 | - | 255 | WP_004152357.1 | DNA polymerase III subunit theta | - |
| M5S85_RS26555 (M5S85_26555) | 106104..106295 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| M5S85_RS26560 (M5S85_26560) | 106338..106844 | - | 507 | WP_001568046.1 | antirestriction protein ArdA | - |
| M5S85_RS26565 (M5S85_26565) | 106887..107315 | - | 429 | WP_004152356.1 | antirestriction protein | - |
| M5S85_RS26570 (M5S85_26570) | 107995..108762 | - | 768 | WP_001568044.1 | hypothetical protein | - |
| M5S85_RS26575 (M5S85_26575) | 108816..109235 | - | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| M5S85_RS26580 (M5S85_26580) | 109245..109466 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| M5S85_RS26585 (M5S85_26585) | 109466..110167 | - | 702 | WP_004152355.1 | DNA methylase | - |
| M5S85_RS26590 (M5S85_26590) | 110239..110408 | - | 170 | Protein_125 | hypothetical protein | - |
| M5S85_RS26595 (M5S85_26595) | 110604..110834 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| M5S85_RS26600 (M5S85_26600) | 110895..111566 | - | 672 | WP_004152354.1 | plasmid partitioning/stability family protein | - |
| M5S85_RS26605 (M5S85_26605) | 111569..112540 | - | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| M5S85_RS26610 (M5S85_26610) | 112772..113203 | + | 432 | WP_004152352.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| M5S85_RS26615 (M5S85_26615) | 113203..114474 | + | 1272 | WP_004152351.1 | Y-family DNA polymerase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|