MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 125598 bp
Accession: NZ_CP103558 Location: 1..125598 Organism: Escherichia coli O25b:H4-ST131 strain 4993 Replicon: plasmid pMB8413_1
Accession: NZ_CP103558 Location: 1..125598 Organism: Escherichia coli O25b:H4-ST131 strain 4993 Replicon: plasmid pMB8413_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5T49_RS26525 (1) | 1..756 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| M5T49_RS26530 (1344) | 1344..2510 | + | 1167 | WP_000772446.1 | hypothetical protein | VF |
| M5T49_RS26535 (2510) | 2510..3481 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5T49_RS26540 (4219) | 4219..5121 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| M5T49_RS26545 (5118) | 5118..5429 | + | 312 | WP_012615291.1 | hypothetical protein | - |
| M5T49_RS26550 (5506) | 5506..6189 | + | 684 | WP_032181561.1 | DNA methylase | - |
| M5T49_RS26555 (6190) | 6190..6411 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| M5T49_RS26560 (6341) | 6341..6859 | + | 519 | WP_223349485.1 | DUF1380 family protein | - |
| M5T49_RS26565 (6904) | 6904..7674 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| M5T49_RS26570 (8088) | 8088..8513 | + | 426 | WP_001546490.1 | antirestriction protein | - |
| M5T49_RS26575 (8560) | 8560..8982 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| M5T49_RS26580 (8979) | 8979..9170 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| M5T49_RS26585 (9442) | 9442..9690 | - | 249 | WP_071781657.1 | hypothetical protein | - |
| M5T49_RS26590 (10202) | 10202..10432 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| M5T49_RS26595 (10484) | 10484..11845 | + | 1362 | WP_000199439.1 | DUF3560 domain-containing protein | - |
| M5T49_RS26600 (11893) | 11893..12458 | + | 566 | Protein_15 | class I SAM-dependent methyltransferase | - |
| M5T49_RS26605 (12484) | 12484..12696 | + | 213 | WP_001348622.1 | hypothetical protein | - |
| M5T49_RS26610 (12609) | 12609..12866 | + | 258 | WP_023147917.1 | hypothetical protein | - |
| M5T49_RS26615 (13106) | 13106..13312 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| M5T49_RS26620 (13990) | 13990..15891 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| M5T49_RS26625 (16041) | 16041..16307 | + | 267 | Protein_20 | single-stranded DNA-binding protein | - |
| M5T49_RS26630 (16362) | 16362..17066 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T49_RS26635 (17132) | 17132..18646 | + | 1515 | Protein_22 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5T49_RS26640 (18688) | 18688..18930 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| M5T49_RS26645 (18962) | 18962..19612 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| M5T49_RS26650 (19718) | 19718..20917 | + | 1200 | WP_000804064.1 | hypothetical protein | ARG |
| M5T49_RS26655 (20949) | 20949..21833 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| M5T49_RS26660 (21971) | 21971..22363 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| M5T49_RS26665 (22367) | 22367..23116 | + | 750 | Protein_28 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M5T49_RS26670 (23140) | 23140..23688 | - | 549 | WP_050497034.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| M5T49_RS26675 (23694) | 23694..24398 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T49_RS26680 (24389) | 24389..29545 | + | 5157 | WP_258742073.1 | hypothetical protein | Relaxase |
| M5T49_RS26685 (29565) | 29565..30311 | + | 747 | WP_023149624.1 | conjugal transfer pilus acetylase TraX | - |
| M5T49_RS26690 (30366) | 30366..30926 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| M5T49_RS26695 (31060) | 31060..31272 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| M5T49_RS26700 (31573) | 31573..31662 | - | 90 | Protein_35 | IS1 family transposase | - |
| M5T49_RS26705 (31717) | 31717..32394 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| M5T49_RS26710 (32394) | 32394..32741 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| M5T49_RS26715 (32761) | 32761..34332 | + | 1572 | WP_023149734.1 | IS66 family transposase ISCro1 | Transposase |
| M5T49_RS26720 (34370) | 34370..34986 | - | 617 | Protein_39 | IS1 family transposase IS1G | Transposase |
| M5T49_RS26725 (35087) | 35087..35269 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - (35408) | 35408..35469 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (35408) | 35408..35469 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (35408) | 35408..35469 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (35408) | 35408..35469 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| M5T49_RS26730 (35513) | 35513..35662 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| M5T49_RS26735 (35946) | 35946..36203 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| M5T49_RS26740 (36439) | 36439..36513 | + | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| M5T49_RS26745 (36506) | 36506..36952 | + | 447 | Protein_44 | plasmid replication initiator RepA | - |
| M5T49_RS26750 (36952) | 36952..37566 | - | 615 | Protein_45 | VENN motif pre-toxin domain-containing protein | - |
| M5T49_RS26755 (38273) | 38273..39493 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| M5T49_RS26760 (39504) | 39504..40415 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| M5T49_RS26765 (40500) | 40500..41504 | + | 1005 | WP_000154545.1 | Ornithine carbamoyltransferase, catabolic | VF |
| M5T49_RS26770 (41552) | 41552..42955 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| M5T49_RS26775 (43036) | 43036..43515 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| M5T49_RS26780 (43579) | 43579..43920 | - | 342 | Protein_51 | transposase | - |
| M5T49_RS26785 (43872) | 43872..44093 | - | 222 | WP_000080227.1 | IS66 family transposase ISEc43 | Transposase |
| M5T49_RS26790 (44124) | 44124..44474 | - | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| M5T49_RS26795 (44471) | 44471..44827 | - | 357 | WP_000229735.1 | transposase | - |
| M5T49_RS26805 (45672) | 45672..46250 | + | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| M5T49_RS26810 (46663) | 46663..47016 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| M5T49_RS26815 (47488) | 47488..48510 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| M5T49_RS26820 (48915) | 48915..49172 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| M5T49_RS26825 (49407) | 49407..49481 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| M5T49_RS26830 (49474) | 49474..50331 | + | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| M5T49_RS26835 (51032) | 51032..51172 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| M5T49_RS26840 (51270) | 51270..51923 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| M5T49_RS26845 (52016) | 52016..52273 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| M5T49_RS26850 (52206) | 52206..52607 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| M5T49_RS26855 (52744) | 52744..55641 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| M5T49_RS26860 (55736) | 55736..55849 | + | 114 | Protein_67 | recombinase family protein | - |
| M5T49_RS26865 (55911) | 55911..56615 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T49_RS26870 (56668) | 56668..57147 | + | 480 | Protein_69 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| M5T49_RS26875 (57332) | 57332..57889 | + | 558 | WP_000108589.1 | OsmC family protein | - |
| M5T49_RS26880 (58031) | 58031..58612 | + | 582 | WP_000210409.1 | hypothetical protein | VF |
| M5T49_RS26885 (58617) | 58617..58955 | + | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| M5T49_RS26890 (58985) | 58985..59314 | - | 330 | WP_002431133.1 | thioredoxin family protein | - |
| M5T49_RS26895 (59528) | 59528..60634 | + | 1107 | WP_000039982.1 | alkene reductase | - |
| M5T49_RS26900 (60700) | 60700..61401 | + | 702 | WP_001194013.1 | DsbA family oxidoreductase | - |
| M5T49_RS26905 (61467) | 61467..62240 | + | 774 | WP_032152933.1 | SDR family oxidoreductase | - |
| M5T49_RS26910 (62426) | 62426..63649 | - | 1224 | WP_000872613.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| M5T49_RS26915 (63780) | 63780..64652 | - | 873 | WP_000090196.1 | DMT family transporter | - |
| M5T49_RS26920 (64894) | 64894..65646 | + | 753 | WP_000734115.1 | alpha/beta hydrolase | - |
| M5T49_RS26925 (65673) | 65673..65986 | + | 314 | Protein_80 | Tn3 family transposase | - |
| M5T49_RS26930 (66037) | 66037..66920 | - | 884 | Protein_81 | IS5 family transposase ISKpn26 | Transposase |
| M5T49_RS26935 (67022) | 67022..67591 | + | 570 | WP_001336919.1 | hypothetical protein | VF |
| M5T49_RS26940 (67594) | 67594..68073 | - | 480 | Protein_83 | IS3 family transposase IS629 | Transposase |
| M5T49_RS26945 (68157) | 68157..69665 | - | 1509 | WP_001189123.1 | group II intron reverse transcriptase/maturase | - |
| M5T49_RS26950 (70338) | 70338..71077 | - | 740 | Protein_85 | IS3 family transposase IS629 | Transposase |
| M5T49_RS26955 (71103) | 71103..71408 | + | 306 | Protein_86 | IS91 family transposase ISSbo1 | Transposase |
| M5T49_RS26960 (71931) | 71931..73106 | - | 1176 | WP_001020413.1 | hypothetical protein | VF |
| M5T49_RS26965 (73175) | 73175..75436 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| M5T49_RS26970 (75605) | 75605..76381 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| M5T49_RS26975 (76389) | 76389..77264 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| M5T49_RS26980 (77596) | 77596..78282 | - | 687 | Protein_91 | replication initiation protein | - |
| M5T49_RS26985 (79734) | 79734..80069 | - | 336 | WP_001080732.1 | colicin E1 family microcin immunity protein | - |
| M5T49_RS26990 (80198) | 80198..80545 | + | 348 | WP_000142452.1 | DUF6404 family protein | - |
| M5T49_RS26995 (80565) | 80565..81134 | - | 570 | WP_000194541.1 | hypothetical protein | - |
| M5T49_RS27000 (81131) | 81131..81391 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| M5T49_RS27005 (81493) | 81493..82565 | + | 1073 | Protein_96 | IS3 family transposase IS629 | Transposase |
| M5T49_RS27010 (82645) | 82645..83049 | + | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| M5T49_RS27015 (83118) | 83118..83822 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T49_RS27020 (83883) | 83883..86294 | + | 2412 | Protein_99 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| M5T49_RS27025 (86328) | 86328..86432 | + | 105 | Protein_100 | IS5/IS1182 family transposase | - |
| M5T49_RS27030 (86582) | 86582..87214 | - | 633 | Protein_101 | histidine-type phosphatase | - |
| M5T49_RS27035 (87336) | 87336..87821 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| M5T49_RS27040 (87846) | 87846..88331 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| M5T49_RS27045 (88318) | 88318..89013 | - | 696 | WP_000117262.1 | hypothetical protein | VF |
| M5T49_RS27050 (89018) | 89018..90148 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| M5T49_RS27055 (90138) | 90138..91421 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| M5T49_RS27060 (91424) | 91424..92803 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| M5T49_RS27065 (92907) | 92907..93434 | - | 528 | WP_000178050.1 | iron transporter | - |
| M5T49_RS27070 (93475) | 93475..95361 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| M5T49_RS27075 (95708) | 95708..96469 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| M5T49_RS27080 (96706) | 96706..97212 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| M5T49_RS27085 (97202) | 97202..97372 | - | 171 | Protein_112 | DsbA family protein | - |
| M5T49_RS27090 (97510) | 97510..97623 | - | 114 | Protein_113 | IS6 family transposase | - |
| M5T49_RS27095 (97823) | 97823..98148 | + | 326 | Protein_114 | IS1 family transposase | - |
| M5T49_RS27100 (98202) | 98202..98906 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5T49_RS27105 (98931) | 98931..99305 | + | 375 | WP_024193849.1 | IS66 family transposase ISKpn24 | Transposase |
| M5T49_RS27110 (99354) | 99354..100299 | + | 946 | Protein_117 | IS66 family transposase ISEc8 | Transposase |
| M5T49_RS27115 (100385) | 100385..101407 | + | 1023 | WP_000255956.1 | IS21 family transposase IS100kyp | Transposase |
| M5T49_RS27120 (101404) | 101404..102186 | + | 783 | WP_001317493.1 | IS21 family transposase IS100kyp | Transposase |
| M5T49_RS27125 (102254) | 102254..102862 | + | 609 | Protein_120 | IS66 family transposase ISEc22 | Transposase |
| M5T49_RS27130 (102925) | 102925..103716 | - | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| M5T49_RS27135 (103723) | 103723..105693 | - | 1971 | WP_001496335.1 | Vitamin B12 transporter BtuB | VF |
| M5T49_RS27140 (105975) | 105975..106399 | + | 425 | Protein_123 | IS3 family transposase IS2 | Transposase |
| M5T49_RS27145 (106936) | 106936..107208 | + | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| M5T49_RS27150 (107654) | 107654..107829 | + | 176 | Protein_125 | IS3 family transposase | - |
| M5T49_RS27155 (108055) | 108055..108651 | - | 597 | WP_231330285.1 | hypothetical protein | - |
| M5T49_RS27160 (108728) | 108728..109425 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| M5T49_RS27165 (109441) | 109441..110001 | - | 561 | Protein_128 | hypothetical protein | - |
| M5T49_RS27170 (110368) | 110368..110556 | + | 189 | WP_001309252.1 | hypothetical protein | - |
| M5T49_RS27175 (110677) | 110677..111417 | + | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| M5T49_RS27180 (111702) | 111702..112679 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| M5T49_RS27185 (113425) | 113425..113748 | + | 324 | Protein_132 | IS21 family transposase IS21 | Transposase |
| M5T49_RS27190 (113750) | 113750..113854 | + | 105 | Protein_133 | AAA family ATPase | - |
| M5T49_RS27195 (113915) | 113915..114428 | + | 514 | Protein_134 | DUF4113 domain-containing protein | - |
| M5T49_RS27205 (115362) | 115362..116002 | + | 641 | Protein_136 | hypothetical protein | VF |
| M5T49_RS27210 (116028) | 116028..118229 | + | 2202 | WP_000973519.1 | Vitamin B12 transporter BtuB | VF |
| M5T49_RS27215 (118755) | 118755..119441 | + | 687 | Protein_138 | IS1 family transposase IS1S | Transposase |
| M5T49_RS27220 (119695) | 119695..120717 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| M5T49_RS27225 (120702) | 120702..122267 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| M5T49_RS27230 (122342) | 122342..122758 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | - |
| M5T49_RS27235 (122755) | 122755..122985 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| M5T49_RS27240 (123545) | 123545..123763 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | - |
| M5T49_RS27245 (123765) | 123765..124070 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | - |
| M5T49_RS27250 (124071) | 124071..124877 | + | 807 | WP_000016970.1 | site-specific integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|