MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 145779 bp
Accession: NZ_CP103500 Location: 1..145779 Organism: Klebsiella pneumoniae strain 5589 Replicon: plasmid pMB9509_1
Accession: NZ_CP103500 Location: 1..145779 Organism: Klebsiella pneumoniae strain 5589 Replicon: plasmid pMB9509_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5S52_RS26090 (M5S52_26090) | 1..1011 | + | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| M5S52_RS26095 (M5S52_26095) | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| M5S52_RS26100 (M5S52_26100) | 3612..4559 | + | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| M5S52_RS26105 (M5S52_26105) | 4586..4897 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| M5S52_RS26110 (M5S52_26110) | 4917..5885 | + | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| M5S52_RS26115 (M5S52_26115) | 6558..6815 | - | 258 | WP_004197688.1 | hypothetical protein | - |
| M5S52_RS26120 (M5S52_26120) | 7456..7971 | + | 516 | Protein_6 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| M5S52_RS26125 (M5S52_26125) | 8035..8871 | + | 837 | WP_004178087.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| M5S52_RS26130 (M5S52_26130) | 9854..11131 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| M5S52_RS26135 (M5S52_26135) | 11194..13191 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| M5S52_RS26150 (M5S52_26150) | 15529..16046 | + | 518 | Protein_12 | IS1 family transposase IS1X2 | Transposase |
| M5S52_RS26155 (M5S52_26155) | 16154..16696 | + | 543 | Protein_13 | ISL3 family transposase ISKpn25 | Transposase |
| M5S52_RS26160 (M5S52_26160) | 16992..17423 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| M5S52_RS26165 (M5S52_26165) | 17674..19149 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| M5S52_RS26170 (M5S52_26170) | 19142..19822 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| M5S52_RS26175 (M5S52_26175) | 20012..21397 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| M5S52_RS26180 (M5S52_26180) | 21426..21779 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| M5S52_RS26185 (M5S52_26185) | 21893..23185 | + | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| M5S52_RS26190 (M5S52_26190) | 23196..26342 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| M5S52_RS26195 (M5S52_26195) | 26429..26869 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| M5S52_RS26200 (M5S52_26200) | 26996..29443 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| M5S52_RS26205 (M5S52_26205) | 29484..29681 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| M5S52_RS26210 (M5S52_26210) | 29715..30452 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| M5S52_RS26215 (M5S52_26215) | 30741..31190 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| M5S52_RS26220 (M5S52_26220) | 31424..33241 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| M5S52_RS26225 (M5S52_26225) | 33247..34137 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| M5S52_RS26230 (M5S52_26230) | 34177..34557 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| M5S52_RS26235 (M5S52_26235) | 34562..35491 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| M5S52_RS26240 (M5S52_26240) | 35546..36226 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| M5S52_RS26245 (M5S52_26245) | 36223..37623 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| M5S52_RS26250 (M5S52_26250) | 37840..38274 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| M5S52_RS26255 (M5S52_26255) | 38506..38685 | - | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| M5S52_RS26260 (M5S52_26260) | 38746..40366 | - | 1621 | Protein_34 | ISL3 family transposase | - |
| M5S52_RS26265 (M5S52_26265) | 40428..40937 | + | 510 | WP_031944101.1 | aquaporin | - |
| M5S52_RS26270 (M5S52_26270) | 40987..41484 | - | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| M5S52_RS26275 (M5S52_26275) | 41816..42142 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| M5S52_RS26280 (M5S52_26280) | 42139..42852 | + | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| M5S52_RS26285 (M5S52_26285) | 42861..43406 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| M5S52_RS26290 (M5S52_26290) | 43482..43844 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| M5S52_RS26295 (M5S52_26295) | 43869..45619 | + | 1751 | Protein_41 | arsenical pump-driving ATPase | - |
| M5S52_RS26300 (M5S52_26300) | 45741..46277 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| M5S52_RS26305 (M5S52_26305) | 46310..46735 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| M5S52_RS26310 (M5S52_26310) | 46748..48037 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| M5S52_RS26315 (M5S52_26315) | 48085..49836 | - | 1752 | WP_004152099.1 | Arsenical pump-driving ATPase | VF |
| M5S52_RS26320 (M5S52_26320) | 49854..50216 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| M5S52_RS26325 (M5S52_26325) | 50266..50616 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| M5S52_RS26330 (M5S52_26330) | 50974..51243 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| M5S52_RS26335 (M5S52_26335) | 51231..51806 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| M5S52_RS26340 (M5S52_26340) | 51837..52331 | + | 495 | WP_004152104.1 | DNA-binding protein | - |
| M5S52_RS26345 (M5S52_26345) | 52375..52743 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| M5S52_RS26350 (M5S52_26350) | 52777..52980 | + | 204 | WP_004152106.1 | HHA domain-containing protein | - |
| M5S52_RS26355 (M5S52_26355) | 53029..53286 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| M5S52_RS26360 (M5S52_26360) | 53362..53616 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| M5S52_RS26365 (M5S52_26365) | 53792..54058 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| M5S52_RS26370 (M5S52_26370) | 54046..54528 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| M5S52_RS26375 (M5S52_26375) | 54740..56086 | + | 1347 | WP_020314316.1 | ISNCY family transposase ISLad2 | Transposase |
| M5S52_RS26380 (M5S52_26380) | 56247..56378 | + | 132 | WP_004218042.1 | hypothetical protein | - |
| M5S52_RS26385 (M5S52_26385) | 56587..57752 | - | 1166 | Protein_59 | IS3 family transposase ISKpn38 | Transposase |
| M5S52_RS26390 (M5S52_26390) | 57929..58891 | - | 963 | WP_004152113.1 | zinc metalloprotease HtpX | - |
| M5S52_RS26395 (M5S52_26395) | 58878..59366 | - | 489 | WP_004152114.1 | phosphate-starvation-inducible PsiE family protein | - |
| M5S52_RS26400 (M5S52_26400) | 59481..59627 | - | 147 | Protein_62 | diguanylate cyclase | - |
| M5S52_RS26405 (M5S52_26405) | 59865..60062 | - | 198 | WP_004152115.1 | hypothetical protein | - |
| M5S52_RS26410 (M5S52_26410) | 60062..62857 | - | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| M5S52_RS26415 (M5S52_26415) | 62972..63541 | - | 570 | WP_004152117.1 | hypothetical protein | VF |
| M5S52_RS26420 (M5S52_26420) | 63576..63857 | - | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| M5S52_RS26425 (M5S52_26425) | 64101..64364 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| M5S52_RS26430 (M5S52_26430) | 64379..64642 | + | 264 | WP_004118209.1 | transposase | - |
| M5S52_RS26435 (M5S52_26435) | 64587..64703 | + | 117 | Protein_69 | transposase domain-containing protein | - |
| M5S52_RS26440 (M5S52_26440) | 64888..65585 | + | 698 | WP_223174644.1 | IS1 family transposase IS1X2 | Transposase |
| M5S52_RS26445 (M5S52_26445) | 65844..66824 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| M5S52_RS26450 (M5S52_26450) | 67406..67925 | - | 520 | Protein_72 | IS5 family transposase ISPst7 | Transposase |
| M5S52_RS26455 (M5S52_26455) | 68033..68902 | - | 870 | WP_004152692.1 | HTH-type transcriptional activator CmpR | VF |
| M5S52_RS26460 (M5S52_26460) | 68896..69906 | - | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| M5S52_RS26465 (M5S52_26465) | 69915..70742 | - | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| M5S52_RS26470 (M5S52_26470) | 70751..71614 | - | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| M5S52_RS26475 (M5S52_26475) | 71611..72438 | - | 828 | WP_004153729.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| M5S52_RS26480 (M5S52_26480) | 72780..73088 | + | 309 | Protein_78 | IS5 family transposase ISThi1 | Transposase |
| M5S52_RS26485 (M5S52_26485) | 73294..73998 | - | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| M5S52_RS26490 (M5S52_26490) | 74010..74666 | - | 657 | WP_000113282.1 | Tetracycline repressor protein class H | VF |
| M5S52_RS26495 (M5S52_26495) | 74762..75946 | + | 1185 | WP_001039466.1 | Tetracycline resistance protein, class B | ARG |
| M5S52_RS26500 (M5S52_26500) | 76041..77150 | + | 1110 | WP_000842134.1 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase | - |
| M5S52_RS26505 (M5S52_26505) | 77172..77594 | + | 423 | Protein_83 | alpha/beta hydrolase-fold protein | - |
| M5S52_RS26510 (M5S52_26510) | 77640..78344 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S52_RS26515 (M5S52_26515) | 78405..79286 | + | 882 | Protein_85 | MFS transporter | - |
| M5S52_RS26520 (M5S52_26520) | 79317..80405 | - | 1089 | WP_001620097.1 | AAA family ATPase | - |
| M5S52_RS26525 (M5S52_26525) | 80492..80752 | - | 261 | WP_023304816.1 | hypothetical protein | - |
| M5S52_RS26530 (M5S52_26530) | 81050..81910 | + | 861 | WP_001620095.1 | Beta-lactamase SHV-1 | ARG |
| M5S52_RS26535 (M5S52_26535) | 81931..82692 | - | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| M5S52_RS26540 (M5S52_26540) | 82953..83855 | + | 903 | WP_002210514.1 | NAD(P)-dependent oxidoreductase | - |
| M5S52_RS26545 (M5S52_26545) | 83867..85132 | + | 1266 | WP_002210515.1 | four-carbon acid sugar kinase family protein | - |
| M5S52_RS26550 (M5S52_26550) | 85125..85745 | + | 621 | WP_002210516.1 | aldolase | - |
| M5S52_RS26555 (M5S52_26555) | 85750..86403 | + | 654 | Protein_93 | 2-oxo-tetronate isomerase | VF |
| M5S52_RS26560 (M5S52_26560) | 86457..87161 | - | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| M5S52_RS26565 (M5S52_26565) | 87238..87561 | - | 324 | Protein_95 | IS3 family transposase ISEc36 | Transposase |
| M5S52_RS26570 (M5S52_26570) | 88038..88310 | + | 273 | WP_000333416.1 | His-Xaa-Ser system protein HxsD | - |
| M5S52_RS26575 (M5S52_26575) | 88310..89698 | + | 1389 | WP_004118216.1 | His-Xaa-Ser system radical SAM maturase HxsB | - |
| M5S52_RS26580 (M5S52_26580) | 89691..90803 | + | 1113 | WP_000005560.1 | His-Xaa-Ser system radical SAM maturase HxsC | - |
| M5S52_RS26585 (M5S52_26585) | 90800..91435 | + | 636 | WP_004118217.1 | His-Xaa-Ser repeat protein HxsA | - |
| M5S52_RS26595 (M5S52_26595) | 92769..93146 | + | 378 | WP_004114613.1 | IS66 family transposase ISSgsp1 | Transposase |
| M5S52_RS26600 (M5S52_26600) | 93143..93490 | + | 348 | WP_004152557.1 | IS66 family transposase ISCfr14 | Transposase |
| M5S52_RS26605 (M5S52_26605) | 93540..95077 | + | 1538 | Protein_103 | IS66 family transposase ISCfr14 | Transposase |
| M5S52_RS26610 (M5S52_26610) | 95115..95492 | + | 378 | Protein_104 | IS66 family transposase ISEc22 | Transposase |
| M5S52_RS26615 (M5S52_26615) | 97313..99046 | - | 1734 | WP_004118832.1 | Glutathione import ATP-binding protein GsiA | VF |
| M5S52_RS26620 (M5S52_26620) | 99054..100001 | - | 948 | WP_004118225.1 | acetamidase/formamidase family protein | - |
| M5S52_RS26625 (M5S52_26625) | 100046..101650 | - | 1605 | WP_004152278.1 | ABC transporter substrate-binding protein | - |
| M5S52_RS26630 (M5S52_26630) | 101663..102583 | - | 921 | WP_004118227.1 | ABC transporter permease | - |
| M5S52_RS26635 (M5S52_26635) | 102583..103431 | - | 849 | WP_004152279.1 | ABC transporter permease | - |
| M5S52_RS26640 (M5S52_26640) | 103428..104021 | - | 594 | WP_004118229.1 | ANTAR domain-containing protein | - |
| M5S52_RS26645 (M5S52_26645) | 104018..105145 | - | 1128 | WP_004118840.1 | transporter substrate-binding protein | - |
| M5S52_RS26650 (M5S52_26650) | 105430..105531 | - | 102 | Protein_112 | IS3 family transposase IS1400 | Transposase |
| M5S52_RS26655 (M5S52_26655) | 105526..105738 | + | 213 | WP_161989521.1 | hypothetical protein | - |
| M5S52_RS26660 (M5S52_26660) | 105739..106224 | + | 486 | Protein_114 | IS21 family transposase ISEc62 | Transposase |
| M5S52_RS26665 (M5S52_26665) | 106494..106563 | - | 70 | Protein_115 | hypothetical protein | - |
| M5S52_RS26670 (M5S52_26670) | 106700..107221 | + | 522 | WP_004118235.1 | putative RNA polymerase sigma factor FecI | VF |
| M5S52_RS26675 (M5S52_26675) | 107218..108171 | + | 954 | WP_004118237.1 | ferric citrate uptake sigma factor regulator FecR | - |
| M5S52_RS26680 (M5S52_26680) | 108257..110581 | + | 2325 | WP_004152280.1 | TonB-dependent Fe(3+) dicitrate receptor FecA | - |
| M5S52_RS26685 (M5S52_26685) | 110626..111528 | + | 903 | WP_004118241.1 | Fe(3+) dicitrate ABC transporter substrate-binding protein FecB | - |
| M5S52_RS26690 (M5S52_26690) | 111525..112523 | + | 999 | WP_004118243.1 | Fe(3+) dicitrate transport system permease protein FecC | VF |
| M5S52_RS26695 (M5S52_26695) | 112520..113476 | + | 957 | WP_004152281.1 | Fe(3+) dicitrate transport system permease protein FecD | VF |
| M5S52_RS26700 (M5S52_26700) | 113477..114244 | + | 768 | WP_004152282.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| M5S52_RS26705 (M5S52_26705) | 114343..114636 | + | 294 | WP_004118251.1 | IS66 family transposase ISKpn24 | Transposase |
| M5S52_RS26710 (M5S52_26710) | 114686..114938 | + | 253 | Protein_124 | IS66 family transposase | - |
| M5S52_RS26715 (M5S52_26715) | 114967..115209 | - | 243 | WP_071527925.1 | EAL domain-containing protein | - |
| M5S52_RS26720 (M5S52_26720) | 115588..116598 | - | 1011 | WP_004152284.1 | zinc-binding alcohol dehydrogenase family protein | - |
| M5S52_RS26725 (M5S52_26725) | 116941..117023 | + | 83 | Protein_127 | hypothetical protein | - |
| M5S52_RS26730 (M5S52_26730) | 117059..118141 | + | 1083 | WP_004152286.1 | DNA-binding transcriptional repressor LacI | - |
| M5S52_RS26735 (M5S52_26735) | 118263..121337 | + | 3075 | WP_004152287.1 | beta-galactosidase | - |
| M5S52_RS26740 (M5S52_26740) | 121389..122642 | + | 1254 | WP_003846917.1 | lactose permease | - |
| M5S52_RS26745 (M5S52_26745) | 122734..123703 | + | 970 | Protein_131 | IS5 family transposase IS903B | Transposase |
| M5S52_RS26750 (M5S52_26750) | 124348..126657 | + | 2310 | WP_004152290.1 | TerB N-terminal domain-containing protein | - |
| M5S52_RS26755 (M5S52_26755) | 126661..127977 | + | 1317 | WP_004152291.1 | ATP-binding protein | - |
| M5S52_RS26760 (M5S52_26760) | 127974..130169 | + | 2196 | WP_000093087.1 | DEAD/DEAH box helicase | - |
| M5S52_RS26765 (M5S52_26765) | 131456..132160 | + | 705 | WP_004217321.1 | IS6 family transposase IS26 | Transposase |
| M5S52_RS26770 (M5S52_26770) | 132214..133311 | + | 1098 | Protein_136 | IS66 family transposase ISPsy43 | Transposase |
| M5S52_RS26775 (M5S52_26775) | 133562..134125 | - | 564 | WP_001097412.1 | chlorite dismutase family protein | - |
| M5S52_RS26780 (M5S52_26780) | 134149..134523 | - | 375 | WP_001348195.1 | cupin domain-containing protein | - |
| M5S52_RS26785 (M5S52_26785) | 134758..135462 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M5S52_RS26790 (M5S52_26790) | 135526..135933 | - | 408 | Protein_140 | DUF945 domain-containing protein | - |
| M5S52_RS26795 (M5S52_26795) | 136767..137180 | - | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| M5S52_RS26800 (M5S52_26800) | 137181..137459 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| M5S52_RS26805 (M5S52_26805) | 137449..137769 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| M5S52_RS26810 (M5S52_26810) | 137850..138074 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| M5S52_RS26815 (M5S52_26815) | 138085..138297 | - | 213 | WP_004152718.1 | hypothetical protein | - |
| M5S52_RS26820 (M5S52_26820) | 138358..138714 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| M5S52_RS26825 (M5S52_26825) | 139350..139700 | - | 351 | WP_004152758.1 | hypothetical protein | - |
| M5S52_RS26830 (M5S52_26830) | 139697..139969 | - | 273 | WP_004152759.1 | hypothetical protein | - |
| M5S52_RS26835 (M5S52_26835) | 140669..140830 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| M5S52_RS26840 (M5S52_26840) | 140902..141936 | + | 1035 | Protein_150 | IS481 family transposase ISKpn28 | Transposase |
| M5S52_RS26845 (M5S52_26845) | 142891..143862 | - | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M5S52_RS26850 (M5S52_26850) | 143862..145028 | - | 1167 | WP_000523813.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|