NZ_CP1034801..143132

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 143132 bp
Accession: NZ_CP103480        Location: 1..143132         Organism: Escherichia coli strain 4621       Replicon: plasmid pMB9635_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T46_RS24560 (1) 1..756 + 756 WP_000852146.1 replication initiation protein RepE -
M5T46_RS24565 (1344) 1344..2510 + 1167 WP_000772446.1 hypothetical protein VF
M5T46_RS24570 (2510) 2510..3481 + 972 WP_000817031.1 ParB/RepB/Spo0J family plasmid partition protein -
M5T46_RS24575 (4219) 4219..5120 + 902 Protein_3 DUF1281 domain-containing protein -
M5T46_RS24580 (5117) 5117..5428 + 312 WP_012615291.1 hypothetical protein -
M5T46_RS24585 (5505) 5505..6188 + 684 WP_040110341.1 DNA methylase -
M5T46_RS24590 (6189) 6189..6410 + 222 WP_001104873.1 hypothetical protein -
M5T46_RS24595 (6340) 6340..6858 + 519 WP_223349485.1 DUF1380 family protein -
M5T46_RS24600 (6903) 6903..7673 + 771 WP_001006251.1 hypothetical protein -
M5T46_RS24605 (8087) 8087..8512 + 426 WP_001546490.1 antirestriction protein -
M5T46_RS24610 (8559) 8559..8981 + 423 WP_000271685.1 DUF1380 family protein -
M5T46_RS24615 (8978) 8978..9169 + 192 WP_001027495.1 hypothetical protein -
M5T46_RS24620 (9441) 9441..9689 - 249 WP_071781657.1 hypothetical protein -
M5T46_RS24625 (10201) 10201..10431 + 231 WP_000218642.1 hypothetical protein -
M5T46_RS24630 (10483) 10483..11844 + 1362 WP_000199439.1 DUF3560 domain-containing protein -
M5T46_RS24635 (11892) 11892..12457 + 566 Protein_15 class I SAM-dependent methyltransferase -
M5T46_RS24640 (12483) 12483..12707 + 225 WP_016238251.1 hypothetical protein -
M5T46_RS24645 (12608) 12608..12877 + 270 WP_071977877.1 hypothetical protein -
M5T46_RS24650 (13117) 13117..13323 + 207 WP_000275856.1 hypothetical protein -
M5T46_RS24655 (13349) 13349..13888 + 540 WP_000290840.1 single-stranded DNA-binding protein -
M5T46_RS24660 (13956) 13956..14189 + 234 WP_000005990.1 DUF905 family protein -
M5T46_RS24665 (14217) 14217..14414 + 198 Protein_21 hypothetical protein -
M5T46_RS24670 (14469) 14469..14903 + 435 WP_000845937.1 conjugation system SOS inhibitor PsiB -
M5T46_RS24675 (14900) 14900..15662 + 763 Protein_23 plasmid SOS inhibition protein A -
M5T46_RS24680 (15631) 15631..15819 - 189 WP_001299721.1 hypothetical protein -
- (15631) 15631..15855 + 225 NuclAT_0 - Antitoxin Detail
- (15631) 15631..15855 + 225 NuclAT_0 - Antitoxin Detail
- (15631) 15631..15855 + 225 NuclAT_0 - Antitoxin Detail
- (15631) 15631..15855 + 225 NuclAT_0 - Antitoxin Detail
M5T46_RS24685 (15841) 15841..15990 + 150 Protein_25 plasmid maintenance protein Mok -
M5T46_RS24690 (15932) 15932..16057 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
M5T46_RS24695 (16277) 16277..16507 + 231 WP_071886920.1 hypothetical protein -
M5T46_RS24700 (16505) 16505..16677 - 173 Protein_28 hypothetical protein -
M5T46_RS24705 (16747) 16747..16953 + 207 WP_000547968.1 hypothetical protein -
M5T46_RS24710 (16978) 16978..17265 + 288 WP_000107535.1 hypothetical protein -
M5T46_RS24715 (17383) 17383..18204 + 822 WP_001234426.1 DUF932 domain-containing protein -
M5T46_RS24720 (18501) 18501..19103 - 603 WP_013362798.1 hypothetical protein VF
M5T46_RS24725 (19424) 19424..19807 + 384 WP_001151524.1 conjugal transfer relaxosome DNA-binding protein TraM -
M5T46_RS24730 (19994) 19994..20683 + 690 WP_000283385.1 conjugal transfer transcriptional regulator TraJ -
M5T46_RS24735 (20776) 20776..21177 + 402 WP_001369361.1 conjugal transfer relaxosome DNA-bindin protein TraY -
M5T46_RS24740 (21210) 21210..21575 + 366 WP_000994779.1 type IV conjugative transfer system pilin TraA -
M5T46_RS24745 (21590) 21590..21901 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
M5T46_RS24750 (21923) 21923..22489 + 567 WP_000399792.1 type IV conjugative transfer system protein TraE -
M5T46_RS24755 (22476) 22476..23204 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
M5T46_RS24760 (23204) 23204..24631 + 1428 WP_000146685.1 F-type conjugal transfer pilus assembly protein TraB -
M5T46_RS24765 (24621) 24621..25211 + 591 WP_000002787.1 conjugal transfer pilus-stabilizing protein TraP -
M5T46_RS24770 (25198) 25198..25395 + 198 WP_001324648.1 conjugal transfer protein TrbD -
M5T46_RS24775 (25407) 25407..25658 + 252 WP_001038342.1 conjugal transfer protein TrbG -
M5T46_RS24780 (25655) 25655..26170 + 516 WP_000809838.1 type IV conjugative transfer system lipoprotein TraV -
M5T46_RS24785 (26305) 26305..26526 + 222 WP_001278689.1 conjugal transfer protein TraR -
M5T46_RS24790 (26686) 26686..29313 + 2628 WP_001064245.1 type IV secretion system protein TraC -
M5T46_RS24795 (29310) 29310..29696 + 387 WP_000099686.1 type-F conjugative transfer system protein TrbI -
M5T46_RS24800 (29693) 29693..30325 + 633 WP_001203726.1 type-F conjugative transfer system protein TraW -
M5T46_RS24805 (30322) 30322..31314 + 993 WP_000830180.1 conjugal transfer pilus assembly protein TraU -
M5T46_RS24810 (31323) 31323..31961 + 639 WP_021518374.1 type-F conjugative transfer system pilin assembly protein TrbC -
M5T46_RS24815 (31958) 31958..33766 + 1809 WP_000821840.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
M5T46_RS24820 (33793) 33793..34050 + 258 WP_000864312.1 conjugal transfer protein TrbE -
M5T46_RS24825 (34043) 34043..34786 + 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
M5T46_RS24830 (34800) 34800..35141 + 342 WP_000556794.1 conjugal transfer protein TrbA -
M5T46_RS24835 (35122) 35122..35457 - 336 WP_000415571.1 hypothetical protein -
M5T46_RS24840 (35538) 35538..35822 + 285 WP_000624105.1 type-F conjugative transfer system pilin chaperone TraQ -
M5T46_RS24845 (35809) 35809..36363 + 555 WP_001553830.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
M5T46_RS24850 (36353) 36353..36667 + 315 WP_023149603.1 P-type conjugative transfer protein TrbJ -
M5T46_RS24855 (36621) 36621..37013 + 393 WP_000164675.1 F-type conjugal transfer protein TrbF -
M5T46_RS24860 (37000) 37000..38373 + 1374 WP_021518370.1 conjugal transfer pilus assembly protein TraH -
M5T46_RS24865 (38370) 38370..41195 + 2826 WP_001553826.1 conjugal transfer mating-pair stabilization protein TraG -
M5T46_RS24870 (41192) 41192..41701 + 510 WP_000628100.1 conjugal transfer entry exclusion protein TraS -
M5T46_RS24875 (41715) 41715..42446 + 732 WP_000850424.1 conjugal transfer complement resistance protein TraT -
M5T46_RS24880 (42698) 42698..44887 + 2190 WP_040110343.1 type IV conjugative transfer system coupling protein TraD -
M5T46_RS24885 (44887) 44887..50007 + 5121 WP_013362805.1 Multifunctional conjugation protein TraI Relaxase
M5T46_RS24890 (50027) 50027..50773 + 747 WP_023149624.1 conjugal transfer pilus acetylase TraX -
M5T46_RS24895 (50828) 50828..51388 + 561 WP_000139363.1 fertility inhibition protein FinO -
M5T46_RS24900 (51522) 51522..51734 + 213 WP_005012601.1 hypothetical protein -
M5T46_RS24905 (52035) 52035..52124 - 90 Protein_69 IS1 family transposase -
M5T46_RS24910 (52179) 52179..52856 + 678 WP_001339397.1 IS66 family transposase ISCro1 Transposase
M5T46_RS24915 (52856) 52856..53203 + 348 WP_000624622.1 IS66 family transposase ISCro1 Transposase
M5T46_RS24920 (53223) 53223..54794 + 1572 WP_023149734.1 IS66 family transposase ISCro1 Transposase
M5T46_RS24925 (54832) 54832..55448 - 617 Protein_73 IS1 family transposase IS1S Transposase
M5T46_RS24930 (55549) 55549..55731 + 183 WP_000968309.1 hypothetical protein -
- (55870) 55870..55931 - 62 NuclAT_1 - Antitoxin Detail
- (55870) 55870..55931 - 62 NuclAT_1 - Antitoxin Detail
- (55870) 55870..55931 - 62 NuclAT_1 - Antitoxin Detail
- (55870) 55870..55931 - 62 NuclAT_1 - Antitoxin Detail
M5T46_RS24935 (55975) 55975..56124 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
M5T46_RS24940 (56408) 56408..56665 + 258 WP_000083833.1 replication regulatory protein RepA -
M5T46_RS24945 (56901) 56901..56975 + 75 WP_032336874.1 RepA leader peptide Tap -
M5T46_RS24950 (56968) 56968..57414 + 447 Protein_78 plasmid replication initiator RepA -
M5T46_RS24955 (57414) 57414..58028 - 615 Protein_79 VENN motif pre-toxin domain-containing protein -
M5T46_RS24960 (58735) 58735..59955 + 1221 WP_000410951.1 arginine deiminase -
M5T46_RS24965 (59966) 59966..60877 + 912 WP_000440183.1 carbamate kinase -
M5T46_RS24970 (60962) 60962..61966 + 1005 WP_000154545.1 Ornithine carbamoyltransferase VF
M5T46_RS24975 (62014) 62014..63417 + 1404 WP_000514417.1 YfcC family protein -
M5T46_RS24980 (63498) 63498..63977 + 480 WP_001496175.1 ArgR family transcriptional regulator -
M5T46_RS24985 (64041) 64041..64382 - 342 Protein_85 IS66 family transposase IS682 Transposase
M5T46_RS24990 (64334) 64334..64555 - 222 WP_000080227.1 hypothetical protein -
M5T46_RS24995 (64586) 64586..64936 - 351 WP_000624725.1 IS66 family transposase ISEc47 Transposase
M5T46_RS25000 (64933) 64933..65289 - 357 WP_000229735.1 transposase -
M5T46_RS25010 (66134) 66134..66712 + 579 WP_032152936.1 DUF2726 domain-containing protein -
M5T46_RS25015 (67125) 67125..67478 - 354 WP_000005489.1 hypothetical protein -
M5T46_RS25020 (67950) 67950..68972 - 1023 WP_000156883.1 IS110 family transposase ISSm1 Transposase
M5T46_RS25025 (69377) 69377..69634 + 258 WP_000083821.1 replication regulatory protein RepA -
M5T46_RS25030 (69869) 69869..69943 + 75 WP_001365705.1 RepA leader peptide Tap -
M5T46_RS25035 (69936) 69936..70793 + 858 WP_048266445.1 incFII family plasmid replication initiator RepA -
M5T46_RS25040 (71494) 71494..71634 + 141 WP_001333237.1 hypothetical protein -
M5T46_RS25045 (71732) 71732..72385 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
M5T46_RS25050 (72478) 72478..72735 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
M5T46_RS25055 (72668) 72668..73069 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
M5T46_RS25060 (73318) 73318..73733 + 416 Protein_100 IS1 family transposase IS1R Transposase
M5T46_RS25065 (73769) 73769..74314 - 546 Protein_101 Tn3 family transposase TnpA_Tn3 Transposase
M5T46_RS25070 (74380) 74380..75084 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5T46_RS25075 (75219) 75219..75314 + 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
M5T46_RS25080 (75440) 75440..76177 + 738 WP_013362818.1 rRNA adenine N-6-methyltransferase ARG
M5T46_RS25085 (76807) 76807..77256 + 450 WP_013362817.1 hypothetical protein -
M5T46_RS25090 (77217) 77217..77558 + 342 WP_023909256.1 60 kDa chaperonin VF
M5T46_RS25095 (77833) 77833..79317 + 1485 WP_032152108.1 IS91 family transposase ISVsa3 Transposase
M5T46_RS25100 (79640) 79640..80344 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5T46_RS25105 (80409) 80409..80588 + 180 Protein_109 IS1380 family transposase -
M5T46_RS25110 (80838) 80838..81713 + 876 WP_032277257.1 Beta-lactamase CTX-M-97 ARG
M5T46_RS25115 (81748) 81748..82716 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
M5T46_RS25120 (82773) 82773..83549 + 777 Protein_112 TonB-dependent receptor -
M5T46_RS25125 (83621) 83621..84325 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
M5T46_RS25130 (84378) 84378..84884 + 507 Protein_114 transposase family protein -
M5T46_RS25135 (84893) 84893..85753 + 861 WP_000493383.1 EamA family transporter -
M5T46_RS25140 (85785) 85785..86984 - 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
M5T46_RS25145 (87090) 87090..87716 + 627 WP_031606906.1 tetracycline resistance transcriptional repressor TetR(A) -
M5T46_RS25150 (87748) 87748..87984 - 237 WP_042005022.1 hypothetical protein -
M5T46_RS25155 (88038) 88038..88874 - 837 WP_000480972.1 hypothetical protein ARG
M5T46_RS25160 (88874) 88874..89677 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
M5T46_RS25165 (89738) 89738..90553 - 816 WP_001043260.1 Dihydropteroate synthase ARG
M5T46_RS25170 (90861) 90861..91037 - 177 Protein_122 replication protein C, IncQ-type -
M5T46_RS25175 (91098) 91098..91802 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5T46_RS25180 (91924) 91924..92829 + 906 WP_000219391.1 hypothetical protein ARG
M5T46_RS25185 (92826) 92826..94064 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
M5T46_RS25190 (94064) 94064..94648 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
M5T46_RS25195 (95141) 95141..95905 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
M5T46_RS25200 (96023) 96023..96088 - 66 Protein_128 EAL domain-containing protein -
M5T46_RS25205 (96132) 96132..96437 - 306 WP_000130000.1 Transcriptional regulator Relaxase
M5T46_RS25210 (96448) 96448..97653 - 1206 WP_000184001.1 chromate efflux transporter -
M5T46_RS25215 (97809) 97809..98012 - 204 WP_000376616.1 hypothetical protein -
M5T46_RS25220 (98140) 98140..98979 - 840 WP_000259031.1 Dihydropteroate synthase ARG
M5T46_RS25225 (98973) 98973..99320 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
M5T46_RS25230 (99526) 99526..100314 - 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
M5T46_RS25235 (100445) 100445..100918 - 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
M5T46_RS25240 (101076) 101076..101825 + 750 Protein_136 IS91 family transposase ISAzo26 Transposase
M5T46_RS25245 (101884) 101884..102588 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
M5T46_RS25250 (102638) 102638..102856 - 219 Protein_138 IS4 family transposase -
M5T46_RS25260 (103768) 103768..103881 + 114 Protein_140 IS6 family transposase IS15DI Transposase
M5T46_RS25265 (104019) 104019..104189 + 171 Protein_141 DsbA family protein -
M5T46_RS25270 (104179) 104179..104685 + 507 WP_000949452.1 protein disulfide oxidoreductase -
M5T46_RS25275 (104922) 104922..105683 + 762 WP_001225378.1 Na(+)-translocating NADH-quinone reductase subunit C -
M5T46_RS25280 (106030) 106030..107916 + 1887 WP_000118029.1 FTR1 family protein -
M5T46_RS25285 (107957) 107957..108484 + 528 WP_000178050.1 iron transporter -
M5T46_RS25290 (108588) 108588..109967 + 1380 WP_000119836.1 Fe-S-containing protein -
M5T46_RS25295 (109970) 109970..111253 + 1284 WP_000964653.1 ABC transporter permease -
M5T46_RS25300 (111243) 111243..112373 + 1131 WP_000729219.1 ABC transporter permease -
M5T46_RS25305 (112378) 112378..113073 + 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
M5T46_RS25310 (113060) 113060..113545 + 486 WP_001267176.1 TlpA disulfide reductase family protein -
M5T46_RS25315 (113570) 113570..114055 + 486 WP_000874189.1 hypothetical protein -
M5T46_RS25320 (114177) 114177..114809 + 633 Protein_152 histidine-type phosphatase -
M5T46_RS25325 (114959) 114959..115063 - 105 Protein_153 IS5/IS1182 family transposase -
M5T46_RS25330 (115097) 115097..117508 - 2412 Protein_154 Tn3 family transposase TnpA_ISSba14 Transposase
M5T46_RS25335 (117569) 117569..118273 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
M5T46_RS25340 (118323) 118323..119258 + 936 Protein_156 IS21 family transposase IS100kyp Transposase
M5T46_RS25345 (119255) 119255..120037 + 783 WP_001317493.1 IS21 family transposase IS100kyp Transposase
M5T46_RS25350 (120105) 120105..120713 + 609 Protein_158 IS66 family transposase ISEc22 Transposase
M5T46_RS25355 (120776) 120776..121567 - 792 WP_000977394.1 DUF4198 domain-containing protein -
M5T46_RS25360 (121574) 121574..123544 - 1971 WP_001496335.1 Hemin receptor VF
M5T46_RS25365 (123826) 123826..124250 + 425 Protein_161 IS3 family transposase IS2 Transposase
M5T46_RS25370 (124787) 124787..125059 + 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
M5T46_RS25375 (125505) 125505..125680 + 176 Protein_163 IS3 family transposase -
M5T46_RS25380 (125906) 125906..127075 - 1170 WP_001072358.1 hypothetical protein -
M5T46_RS25385 (127447) 127447..127635 + 189 WP_001309252.1 hypothetical protein -
M5T46_RS25390 (127756) 127756..128496 + 741 WP_001066953.1 tyrosine-type recombinase/integrase -
M5T46_RS25395 (128781) 128781..129758 - 978 WP_000361611.1 RepB family plasmid replication initiator protein -
M5T46_RS25400 (130504) 130504..130827 + 324 Protein_168 IS21 family transposase IS21 Transposase
M5T46_RS25405 (130829) 130829..130933 + 105 Protein_169 AAA family ATPase -
M5T46_RS25410 (130994) 130994..131507 + 514 Protein_170 DUF4113 domain-containing protein -
M5T46_RS25415 (131687) 131687..132373 - 687 Protein_171 IS1 family transposase IS1S Transposase
M5T46_RS25420 (132729) 132729..133643 + 915 WP_000949005.1 putative periplasmic iron-binding protein VF
M5T46_RS25425 (133643) 133643..134470 + 828 WP_000983710.1 Manganese transport system ATP-binding protein MntB VF
M5T46_RS25430 (134467) 134467..135324 + 858 WP_001101723.1 Manganese transport system membrane protein MntB ARG
M5T46_RS25435 (135321) 135321..136178 + 858 WP_000968139.1 Manganese transport system membrane protein MntB ARG
M5T46_RS25440 (136289) 136289..136975 + 687 Protein_176 IS1 family transposase IS1S Transposase
M5T46_RS25445 (137229) 137229..138251 - 1023 WP_000361402.1 helicase UvrD -
M5T46_RS25450 (138236) 138236..139801 - 1566 WP_001128474.1 AAA family ATPase -
M5T46_RS25455 (139876) 139876..140292 - 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin -
M5T46_RS25460 (140289) 140289..140519 - 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin -
M5T46_RS25465 (141079) 141079..141297 + 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA -
M5T46_RS25470 (141299) 141299..141604 + 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB -
M5T46_RS25475 (141605) 141605..142411 + 807 WP_000016970.1 site-specific integrase -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance