MGE detailed information
MGE type: Mobilizable plasmid MGE length: 101130 bp
Accession: NZ_CP102885 Location: 1..101130 Organism: Klebsiella pneumoniae strain KH2 Replicon: plasmid pKH2-2
Accession: NZ_CP102885 Location: 1..101130 Organism: Klebsiella pneumoniae strain KH2 Replicon: plasmid pKH2-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M2890_RS27305 (M2890_27305) | 19..894 | + | 876 | WP_004098982.1 | replication initiation protein | - |
| M2890_RS27310 (M2890_27310) | 1519..2145 | + | 627 | WP_004098977.1 | hypothetical protein | VF |
| M2890_RS27315 (M2890_27315) | 2142..2444 | + | 303 | WP_004197636.1 | hypothetical protein | - |
| M2890_RS27320 (M2890_27320) | 2978..3666 | + | 689 | Protein_3 | IS3 family transposase | - |
| M2890_RS27325 (M2890_27325) | 4339..5847 | + | 1509 | WP_001189111.1 | group II intron reverse transcriptase/maturase | - |
| M2890_RS27330 (M2890_27330) | 5928..6107 | + | 180 | Protein_5 | DDE-type integrase/transposase/recombinase | - |
| M2890_RS27335 (M2890_27335) | 6389..7465 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| M2890_RS27340 (M2890_27340) | 7482..7790 | + | 309 | Protein_7 | integrase core domain-containing protein | - |
| M2890_RS27345 (M2890_27345) | 7765..8115 | - | 351 | Protein_8 | Tyrosine recombinase XerC | VF |
| M2890_RS27350 (M2890_27350) | 8178..8882 | + | 705 | WP_020324562.1 | IS6 family transposase IS26 | Transposase |
| M2890_RS27355 (M2890_27355) | 8773..9180 | - | 408 | WP_074428709.1 | recombinase family protein | - |
| M2890_RS27360 (M2890_27360) | 9573..10586 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| M2890_RS27365 (M2890_27365) | 10878..11432 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| M2890_RS27370 (M2890_27370) | 11529..11981 | + | 453 | WP_001749986.1 | hypothetical protein | ARG |
| M2890_RS27375 (M2890_27375) | 12114..12587 | + | 474 | WP_001749985.1 | Dihydrofolate reductase type 1 | ARG |
| M2890_RS27380 (M2890_27380) | 12768..13613 | + | 846 | WP_001749984.1 | Streptomycin 3''-adenylyltransferase | ARG |
| M2890_RS27385 (M2890_27385) | 13730..14077 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| M2890_RS27390 (M2890_27390) | 14071..14910 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| M2890_RS27395 (M2890_27395) | 15315..16856 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| M2890_RS27400 (M2890_27400) | 17089..17628 | - | 540 | Protein_19 | ABC transporter substrate-binding protein | - |
| M2890_RS27405 (M2890_27405) | 18163..18615 | + | 453 | WP_003833285.1 | SgcJ/EcaC family oxidoreductase | - |
| M2890_RS27410 (M2890_27410) | 18657..19301 | - | 645 | WP_063866158.1 | Pentapeptide repeat protein | ARG |
| M2890_RS27415 (M2890_27415) | 19397..19603 | - | 207 | Protein_22 | phage shock protein operon transcriptional activator | - |
| M2890_RS27420 (M2890_27420) | 19595..19798 | + | 204 | Protein_23 | SMR family transporter | - |
| M2890_RS27425 (M2890_27425) | 19792..20631 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| M2890_RS27430 (M2890_27430) | 20759..21259 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| M2890_RS27435 (M2890_27435) | 21580..21648 | + | 69 | Protein_26 | EAL domain-containing protein | - |
| M2890_RS27440 (M2890_27440) | 21766..22530 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| M2890_RS27445 (M2890_27445) | 22670..22735 | - | 66 | Protein_28 | EAL domain-containing protein | - |
| M2890_RS27450 (M2890_27450) | 22791..24005 | + | 1215 | WP_004098817.1 | type II site-specific deoxyribonuclease | - |
| M2890_RS27455 (M2890_27455) | 24039..25472 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| M2890_RS27460 (M2890_27460) | 25571..25843 | + | 273 | Protein_31 | IS1 family transposase IS1X2 | Transposase |
| M2890_RS27465 (M2890_27465) | 25854..26060 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| M2890_RS27470 (M2890_27470) | 26065..26577 | - | 513 | WP_071549088.1 | restriction endonuclease | - |
| M2890_RS27475 (M2890_27475) | 26602..27306 | + | 705 | WP_020324562.1 | IS6 family transposase IS26 | Transposase |
| M2890_RS27480 (M2890_27480) | 28058..28546 | + | 489 | WP_258323943.1 | plasmid stabilization protein StbA | - |
| M2890_RS27485 (M2890_27485) | 28555..28746 | + | 192 | WP_000861580.1 | hypothetical protein | - |
| M2890_RS27490 (M2890_27490) | 28757..29224 | - | 468 | Protein_37 | IS1 family transposase | - |
| M2890_RS27495 (M2890_27495) | 29758..30513 | + | 756 | WP_258323944.1 | replication initiation protein RepE | - |
| M2890_RS27500 (M2890_27500) | 30782..31141 | + | 360 | Protein_39 | IS1 family transposase IS1X4 | Transposase |
| M2890_RS27505 (M2890_27505) | 31825..31908 | + | 84 | Protein_40 | SOS response-associated peptidase | - |
| M2890_RS27510 (M2890_27510) | 31966..32934 | - | 969 | WP_000654802.1 | IS5 family transposase IS903B | Transposase |
| M2890_RS27515 (M2890_27515) | 33515..33901 | + | 387 | WP_001039464.1 | plasmid stabilization protein StbA | - |
| M2890_RS27520 (M2890_27520) | 34041..35009 | - | 969 | WP_020956880.1 | IS5 family transposase IS903B | Transposase |
| M2890_RS27525 (M2890_27525) | 36005..36313 | - | 309 | Protein_44 | replication initiation protein | - |
| M2890_RS27535 (M2890_27535) | 37172..38659 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| M2890_RS27540 (M2890_27540) | 39065..39496 | + | 432 | WP_000776034.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| M2890_RS27545 (M2890_27545) | 39496..40767 | + | 1272 | WP_004118291.1 | Y-family DNA polymerase | - |
| M2890_RS27550 (M2890_27550) | 40849..41823 | - | 975 | WP_000064120.1 | ParB family protein | - |
| M2890_RS27555 (M2890_27555) | 41823..43028 | - | 1206 | WP_000368714.1 | AAA family ATPase | - |
| M2890_RS27560 (M2890_27560) | 43443..43712 | + | 270 | WP_000339857.1 | hypothetical protein | - |
| M2890_RS27565 (M2890_27565) | 43889..44755 | - | 867 | WP_004118283.1 | replication initiation protein | - |
| M2890_RS27570 (M2890_27570) | 45285..45389 | + | 105 | WP_032409716.1 | hypothetical protein | - |
| M2890_RS27575 (M2890_27575) | 45518..45775 | + | 258 | WP_000764642.1 | hypothetical protein | - |
| M2890_RS27580 (M2890_27580) | 45833..46609 | - | 777 | WP_020956881.1 | tyrosine-type recombinase/integrase | - |
| M2890_RS27585 (M2890_27585) | 46621..47307 | - | 687 | WP_020956882.1 | hypothetical protein | - |
| M2890_RS27590 (M2890_27590) | 47371..47664 | - | 294 | WP_020956883.1 | hypothetical protein | - |
| M2890_RS27595 (M2890_27595) | 47823..48284 | - | 462 | WP_074193041.1 | hypothetical protein | - |
| M2890_RS27600 (M2890_27600) | 48241..48471 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| M2890_RS27605 (M2890_27605) | 48468..48884 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M2890_RS27610 (M2890_27610) | 48958..50520 | + | 1563 | WP_004206609.1 | AAA family ATPase | - |
| M2890_RS27615 (M2890_27615) | 50505..51527 | + | 1023 | WP_000361404.1 | helicase UvrD | - |
| M2890_RS27620 (M2890_27620) | 52071..52979 | + | 909 | WP_032411229.1 | HNH endonuclease | - |
| M2890_RS27625 (M2890_27625) | 53165..53515 | - | 351 | WP_004187110.1 | DUF305 domain-containing protein | - |
| M2890_RS27630 (M2890_27630) | 53663..54094 | - | 432 | WP_004187113.1 | silver-binding protein SilE | - |
| M2890_RS27635 (M2890_27635) | 54345..55820 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| M2890_RS27640 (M2890_27640) | 55813..56493 | - | 681 | WP_065801211.1 | Transcriptional regulatory protein CusR | VF |
| M2890_RS27645 (M2890_27645) | 56683..58068 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| M2890_RS27650 (M2890_27650) | 58097..58450 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| M2890_RS27655 (M2890_27655) | 58564..59856 | + | 1293 | WP_032413333.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| M2890_RS27660 (M2890_27660) | 59867..63013 | + | 3147 | WP_000574021.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| M2890_RS27665 (M2890_27665) | 63100..63540 | + | 441 | WP_008322815.1 | DUF411 domain-containing protein | - |
| M2890_RS27670 (M2890_27670) | 63667..66114 | + | 2448 | WP_032413330.1 | Ag(+)-translocating P-type ATPase SilP | - |
| M2890_RS27675 (M2890_27675) | 66155..66352 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| M2890_RS27680 (M2890_27680) | 66386..67123 | - | 738 | WP_000287501.1 | Murein DD-endopeptidase MepM | VF |
| M2890_RS27685 (M2890_27685) | 67426..68457 | - | 1032 | WP_142675176.1 | Methyl-accepting chemotaxis protein McpQ | VF |
| M2890_RS27690 (M2890_27690) | 68658..68885 | + | 228 | Protein_77 | IS1380 family transposase ISEcp1 | Transposase |
| M2890_RS27700 (M2890_27700) | 69616..70014 | + | 399 | Protein_79 | IS1380 family transposase ISEcp1 | Transposase |
| M2890_RS27705 (M2890_27705) | 70264..71139 | + | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| M2890_RS27710 (M2890_27710) | 71174..72142 | + | 969 | WP_020956916.1 | IS5 family transposase IS903B | Transposase |
| M2890_RS27715 (M2890_27715) | 72199..73296 | + | 1098 | Protein_82 | TonB-dependent receptor | - |
| M2890_RS27720 (M2890_27720) | 73364..73900 | - | 537 | Protein_83 | PAS domain-containing protein | - |
| M2890_RS27725 (M2890_27725) | 74160..74417 | + | 258 | Protein_84 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| M2890_RS27730 (M2890_27730) | 74719..74994 | + | 276 | WP_001141270.1 | formaldehyde-responsive transcriptional repressor FrmR | - |
| M2890_RS27735 (M2890_27735) | 75025..76134 | + | 1110 | WP_000842086.1 | S-(hydroxymethyl)glutathione dehydrogenase | - |
| M2890_RS27740 (M2890_27740) | 76176..76574 | + | 399 | WP_008813494.1 | VOC family protein | - |
| M2890_RS27745 (M2890_27745) | 76638..77474 | + | 837 | WP_047671991.1 | S-formylglutathione hydrolase | - |
| M2890_RS27750 (M2890_27750) | 77502..78137 | - | 636 | WP_000470623.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| M2890_RS27755 (M2890_27755) | 78305..81292 | + | 2988 | WP_000124025.1 | Tn3 family transposase TnpA_TnEc1 | Transposase |
| M2890_RS27760 (M2890_27760) | 81322..81624 | + | 303 | Protein_91 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| M2890_RS27765 (M2890_27765) | 81627..84593 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| M2890_RS27770 (M2890_27770) | 84527..85003 | + | 477 | WP_223171565.1 | hypothetical protein | - |
| M2890_RS27775 (M2890_27775) | 85088..85792 | - | 705 | WP_001067784.1 | IS6 family transposase IS1006 | Transposase |
| M2890_RS27780 (M2890_27780) | 85856..86686 | + | 831 | Protein_95 | IS91 family transposase ISVsa3 | Transposase |
| M2890_RS27785 (M2890_27785) | 86717..87601 | + | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| M2890_RS27790 (M2890_27790) | 87818..89032 | + | 1215 | WP_000214122.1 | Bicyclomycin resistance protein | ARG |
| M2890_RS27795 (M2890_27795) | 89306..89530 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| M2890_RS27800 (M2890_27800) | 89527..90264 | - | 738 | WP_001446887.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| M2890_RS27805 (M2890_27805) | 90750..90890 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| M2890_RS27810 (M2890_27810) | 90896..91600 | - | 705 | WP_020324562.1 | IS6 family transposase IS26 | Transposase |
| M2890_RS27815 (M2890_27815) | 91591..91995 | + | 405 | WP_077268520.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| M2890_RS27820 (M2890_27820) | 92752..94221 | + | 1470 | WP_004201235.1 | HNH endonuclease signature motif containing protein | - |
| M2890_RS27825 (M2890_27825) | 94741..95478 | - | 738 | WP_004201234.1 | hypothetical protein | - |
| M2890_RS27830 (M2890_27830) | 95616..96302 | - | 687 | WP_004201232.1 | NYN domain-containing protein | - |
| M2890_RS27835 (M2890_27835) | 98130..98834 | + | 705 | WP_020324562.1 | IS6 family transposase IS26 | Transposase |
| M2890_RS27840 (M2890_27840) | 98932..100052 | + | 1121 | WP_087759376.1 | IS3 family transposase ISRaq1 | Transposase |
| M2890_RS27845 (M2890_27845) | 100111..100737 | + | 627 | Protein_108 | DUF4113 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|