MGE detailed information
MGE type: Conjugative plasmid MGE length: 118931 bp
Accession: NZ_CP102872 Location: 1..118931 Organism: Klebsiella pneumoniae strain KA2 Replicon: plasmid pKA2-3-mcr8.1
Accession: NZ_CP102872 Location: 1..118931 Organism: Klebsiella pneumoniae strain KA2 Replicon: plasmid pKA2-3-mcr8.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NWT85_RS27840 (NWT85_27840) | 1..1014 | + | 1014 | WP_063267105.1 | plasmid replication initiator RepA | - |
| NWT85_RS27845 (NWT85_27845) | 1924..2598 | + | 675 | WP_118860660.1 | SOS response-associated peptidase | - |
| NWT85_RS27850 (NWT85_27850) | 2895..3461 | + | 567 | Protein_2 | hypothetical protein | - |
| NWT85_RS27855 (NWT85_27855) | 3496..4794 | - | 1299 | Protein_3 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NWT85_RS27860 (NWT85_27860) | 4862..5565 | + | 704 | Protein_4 | IS6 family transposase IS26 | Transposase |
| NWT85_RS27865 (NWT85_27865) | 5759..6145 | + | 387 | WP_063102497.1 | bleomycin binding protein | - |
| NWT85_RS27870 (NWT85_27870) | 6465..6857 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| NWT85_RS27875 (NWT85_27875) | 7099..7803 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NWT85_RS27880 (NWT85_27880) | 7912..8946 | + | 1035 | Protein_8 | IS481 family transposase ISKpn28 | Transposase |
| NWT85_RS27885 (NWT85_27885) | 9226..10335 | + | 1110 | WP_258335065.1 | NADH:flavin oxidoreductase | - |
| NWT85_RS27890 (NWT85_27890) | 10366..11010 | + | 645 | WP_258335066.1 | sugar nucleotide-binding protein | - |
| NWT85_RS27895 (NWT85_27895) | 11023..11484 | - | 462 | WP_258335068.1 | outer membrane protein transport protein | - |
| NWT85_RS27900 (NWT85_27900) | 11537..12088 | + | 552 | Protein_12 | IS91 family transposase ISPps1 | Transposase |
| NWT85_RS27905 (NWT85_27905) | 12221..12532 | - | 312 | WP_142084267.1 | 50S ribosome-binding protein YggL | - |
| NWT85_RS27910 (NWT85_27910) | 12644..12931 | - | 288 | WP_258335069.1 | TonB-dependent receptor | - |
| NWT85_RS27915 (NWT85_27915) | 12848..14482 | + | 1635 | Protein_15 | BREX-1 system phosphatase PglZ type A | - |
| NWT85_RS27920 (NWT85_27920) | 14495..15073 | + | 579 | Protein_16 | BREX system Lon protease-like protein BrxL | - |
| NWT85_RS27925 (NWT85_27925) | 15126..15830 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NWT85_RS27930 (NWT85_27930) | 16146..16703 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NWT85_RS27935 (NWT85_27935) | 16886..17746 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NWT85_RS27940 (NWT85_27940) | 18005..18481 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| NWT85_RS27945 (NWT85_27945) | 18528..19403 | - | 876 | WP_011091028.1 | Beta-lactamase CTX-M-1 | ARG |
| NWT85_RS27950 (NWT85_27950) | 19738..21000 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| NWT85_RS27955 (NWT85_27955) | 21311..21748 | + | 438 | Protein_23 | hypothetical protein | - |
| NWT85_RS27960 (NWT85_27960) | 21820..22143 | + | 324 | WP_187993889.1 | hypothetical protein | - |
| NWT85_RS27965 (NWT85_27965) | 22390..23358 | + | 969 | WP_172691958.1 | IS5 family transposase IS903B | Transposase |
| NWT85_RS27970 (NWT85_27970) | 23715..23828 | + | 114 | Protein_26 | phosphoenolpyruvate hydrolase family protein | - |
| NWT85_RS27975 (NWT85_27975) | 23840..25213 | + | 1374 | WP_117252078.1 | serine hydrolase domain-containing protein | - |
| NWT85_RS27980 (NWT85_27980) | 25500..25970 | - | 471 | WP_072310984.1 | GyrI-like domain-containing protein | - |
| NWT85_RS27985 (NWT85_27985) | 26568..27374 | + | 807 | WP_072310988.1 | MipA/OmpV family protein | - |
| NWT85_RS27990 (NWT85_27990) | 27383..28474 | + | 1092 | WP_223349403.1 | serine hydrolase domain-containing protein | - |
| NWT85_RS27995 (NWT85_27995) | 28494..28850 | + | 357 | WP_072310983.1 | hypothetical protein | - |
| NWT85_RS28000 (NWT85_28000) | 28874..29407 | + | 534 | WP_072310982.1 | hypothetical protein | - |
| NWT85_RS28005 (NWT85_28005) | 29409..29618 | + | 210 | WP_072310981.1 | helix-turn-helix transcriptional regulator | - |
| NWT85_RS28010 (NWT85_28010) | 29816..30715 | + | 900 | WP_118842312.1 | hypothetical protein | VF |
| NWT85_RS28015 (NWT85_28015) | 31163..31552 | - | 390 | WP_118842310.1 | diacylglycerol kinase | - |
| NWT85_RS28020 (NWT85_28020) | 31666..32895 | - | 1230 | WP_072310978.1 | HAMP domain-containing sensor histidine kinase | - |
| NWT85_RS28025 (NWT85_28025) | 32917..33612 | - | 696 | WP_072310977.1 | Transcriptional activator protein CopR | VF |
| NWT85_RS28030 (NWT85_28030) | 33712..35409 | + | 1698 | WP_114699275.1 | phosphoethanolamine--lipid A transferase MCR-8.1 | VF |
| NWT85_RS28035 (NWT85_28035) | 35516..36406 | + | 891 | WP_118842309.1 | hypothetical protein | VF |
| NWT85_RS28040 (NWT85_28040) | 36651..37160 | + | 510 | WP_032445709.1 | GNAT family N-acetyltransferase | - |
| NWT85_RS28045 (NWT85_28045) | 38099..38797 | - | 699 | WP_032445707.1 | DJ-1/PfpI family protein | - |
| NWT85_RS28050 (NWT85_28050) | 39087..39437 | - | 351 | WP_223349401.1 | hypothetical protein | - |
| NWT85_RS28055 (NWT85_28055) | 39494..39697 | - | 204 | WP_072010199.1 | hemolysin expression modulator Hha | - |
| NWT85_RS28060 (NWT85_28060) | 39769..40737 | + | 969 | WP_075211999.1 | IS5 family transposase IS903 | Transposase |
| NWT85_RS28065 (NWT85_28065) | 41209..42000 | - | 792 | WP_221928726.1 | ribbon-helix-helix domain-containing protein | - |
| NWT85_RS28070 (NWT85_28070) | 42183..43211 | - | 1029 | WP_032445668.1 | Abi family protein | - |
| NWT85_RS28075 (NWT85_28075) | 43372..43953 | - | 582 | WP_072310991.1 | hypothetical protein | - |
| NWT85_RS28080 (NWT85_28080) | 44522..44740 | + | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NWT85_RS28085 (NWT85_28085) | 44742..45047 | + | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NWT85_RS28090 (NWT85_28090) | 45216..45611 | + | 396 | WP_017899885.1 | hypothetical protein | - |
| NWT85_RS28095 (NWT85_28095) | 45638..45952 | + | 315 | WP_053389906.1 | hypothetical protein | - |
| NWT85_RS28100 (NWT85_28100) | 46247..46963 | + | 717 | Protein_52 | hypothetical protein | - |
| NWT85_RS28105 (NWT85_28105) | 47161..47946 | + | 786 | WP_046664219.1 | site-specific integrase | - |
| NWT85_RS28110 (NWT85_28110) | 48395..49150 | + | 756 | WP_001568031.1 | replication initiation protein RepE | - |
| NWT85_RS28115 (NWT85_28115) | 50135..50767 | + | 633 | WP_017901447.1 | ParA family protein | - |
| NWT85_RS28120 (NWT85_28120) | 50767..51141 | + | 375 | WP_017901448.1 | hypothetical protein | - |
| NWT85_RS28125 (NWT85_28125) | 51381..52355 | + | 975 | WP_020801689.1 | plasmid segregation protein ParM | - |
| NWT85_RS28130 (NWT85_28130) | 52359..52751 | + | 393 | WP_046664218.1 | plasmid partitioning/stability family protein | - |
| NWT85_RS28135 (NWT85_28135) | 53321..53542 | - | 222 | WP_046664217.1 | helix-turn-helix domain-containing protein | - |
| NWT85_RS28140 (NWT85_28140) | 53573..54019 | - | 447 | WP_046664216.1 | hypothetical protein | - |
| NWT85_RS28145 (NWT85_28145) | 54290..54595 | - | 306 | WP_172691974.1 | hypothetical protein | - |
| NWT85_RS28150 (NWT85_28150) | 54649..54900 | - | 252 | WP_047368872.1 | plasmid stabilization protein | - |
| NWT85_RS28155 (NWT85_28155) | 54979..56250 | - | 1272 | WP_004206782.1 | Y-family DNA polymerase | - |
| NWT85_RS28160 (NWT85_28160) | 56250..56675 | - | 426 | WP_258335067.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NWT85_RS28165 (NWT85_28165) | 57078..58565 | + | 1488 | WP_161952885.1 | hypothetical protein | VF |
| NWT85_RS28170 (NWT85_28170) | 58799..59029 | + | 231 | WP_004206779.1 | hypothetical protein | - |
| NWT85_RS28175 (NWT85_28175) | 59550..59975 | + | 426 | WP_186920192.1 | antirestriction protein | - |
| NWT85_RS28180 (NWT85_28180) | 60211..60465 | + | 255 | WP_049139361.1 | DNA polymerase III subunit theta | - |
| NWT85_RS28185 (NWT85_28185) | 60500..60817 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| NWT85_RS28190 (NWT85_28190) | 61600..61827 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| NWT85_RS28195 (NWT85_28195) | 61919..62149 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| NWT85_RS28200 (NWT85_28200) | 62201..63556 | + | 1356 | WP_258335061.1 | DUF3560 domain-containing protein | - |
| NWT85_RS28205 (NWT85_28205) | 63604..64167 | + | 564 | WP_004152756.1 | methyltransferase | - |
| NWT85_RS28210 (NWT85_28210) | 64998..65540 | + | 543 | WP_073558210.1 | single-stranded DNA-binding protein | - |
| NWT85_RS28215 (NWT85_28215) | 65589..65837 | + | 249 | WP_032431380.1 | DUF905 domain-containing protein | - |
| NWT85_RS28220 (NWT85_28220) | 65907..67964 | + | 2058 | WP_117092697.1 | ParB/RepB/Spo0J family partition protein | - |
| NWT85_RS28225 (NWT85_28225) | 68009..68440 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| NWT85_RS28230 (NWT85_28230) | 68437..69165 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| NWT85_RS28235 (NWT85_28235) | 69162..69488 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| NWT85_RS28240 (NWT85_28240) | 69544..69918 | + | 375 | WP_001568060.1 | hypothetical protein | - |
| NWT85_RS28245 (NWT85_28245) | 70122..71491 | + | 1370 | WP_085956500.1 | IS3 family transposase ISKpn8 | Transposase |
| NWT85_RS28250 (NWT85_28250) | 71549..72622 | - | 1074 | WP_087652798.1 | IS481 family transposase ISKpn28 | Transposase |
| NWT85_RS28255 (NWT85_28255) | 72736..72852 | + | 117 | WP_055313929.1 | type I toxin-antitoxin system Hok family toxin | - |
| NWT85_RS28260 (NWT85_28260) | 73550..73822 | + | 273 | WP_023287105.1 | hypothetical protein | - |
| NWT85_RS28265 (NWT85_28265) | 73819..74169 | + | 351 | WP_013023809.1 | hypothetical protein | - |
| NWT85_RS28270 (NWT85_28270) | 74184..74501 | + | 318 | WP_015065519.1 | hypothetical protein | - |
| NWT85_RS28275 (NWT85_28275) | 75397..75753 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| NWT85_RS28280 (NWT85_28280) | 75814..76026 | + | 213 | WP_019706020.1 | hypothetical protein | - |
| NWT85_RS28285 (NWT85_28285) | 76037..76261 | + | 225 | WP_087652801.1 | hypothetical protein | - |
| NWT85_RS28290 (NWT85_28290) | 76342..76662 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NWT85_RS28295 (NWT85_28295) | 76652..76930 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| NWT85_RS28300 (NWT85_28300) | 76931..77344 | + | 414 | WP_020316683.1 | helix-turn-helix domain-containing protein | - |
| NWT85_RS28305 (NWT85_28305) | 78173..78994 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| NWT85_RS28310 (NWT85_28310) | 79027..79356 | + | 330 | WP_011977736.1 | DUF5983 family protein | - |
| NWT85_RS28315 (NWT85_28315) | 79389..79874 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| NWT85_RS28320 (NWT85_28320) | 80265..80681 | + | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NWT85_RS28325 (NWT85_28325) | 80881..81600 | + | 720 | WP_162866174.1 | conjugal transfer protein TrbJ | - |
| NWT85_RS28330 (NWT85_28330) | 81733..81939 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| NWT85_RS28335 (NWT85_28335) | 82001..82369 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| NWT85_RS28340 (NWT85_28340) | 82383..82688 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| NWT85_RS28345 (NWT85_28345) | 82708..83274 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| NWT85_RS28350 (NWT85_28350) | 83261..84001 | + | 741 | WP_117087731.1 | type-F conjugative transfer system secretin TraK | - |
| NWT85_RS28355 (NWT85_28355) | 84001..85425 | + | 1425 | WP_004194260.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NWT85_RS28360 (NWT85_28360) | 85498..86082 | + | 585 | WP_032440547.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NWT85_RS28365 (NWT85_28365) | 86405..86623 | + | 219 | WP_004195468.1 | hypothetical protein | - |
| NWT85_RS28370 (NWT85_28370) | 86624..86935 | + | 312 | WP_117087732.1 | hypothetical protein | - |
| NWT85_RS28375 (NWT85_28375) | 87002..87406 | + | 405 | WP_114507349.1 | hypothetical protein | - |
| NWT85_RS28380 (NWT85_28380) | 87531..87776 | + | 246 | WP_087652776.1 | hypothetical protein | - |
| NWT85_RS28385 (NWT85_28385) | 87784..88182 | + | 399 | WP_164979614.1 | hypothetical protein | - |
| NWT85_RS28390 (NWT85_28390) | 88254..90893 | + | 2640 | WP_258335062.1 | type IV secretion system protein TraC | - |
| NWT85_RS28395 (NWT85_28395) | 90893..91282 | + | 390 | WP_040107933.1 | type-F conjugative transfer system protein TrbI | - |
| NWT85_RS28400 (NWT85_28400) | 91282..91917 | + | 636 | WP_085551873.1 | type-F conjugative transfer system protein TraW | - |
| NWT85_RS28405 (NWT85_28405) | 91952..92353 | + | 402 | WP_044265012.1 | hypothetical protein | - |
| NWT85_RS28410 (NWT85_28410) | 92350..93339 | + | 990 | WP_046664201.1 | conjugal transfer pilus assembly protein TraU | - |
| NWT85_RS28415 (NWT85_28415) | 93360..93536 | + | 177 | WP_162866177.1 | hypothetical protein | - |
| NWT85_RS28420 (NWT85_28420) | 93615..94262 | + | 648 | WP_114507347.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NWT85_RS28425 (NWT85_28425) | 94321..96276 | + | 1956 | WP_117061680.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NWT85_RS28430 (NWT85_28430) | 96308..96562 | + | 255 | WP_073558194.1 | conjugal transfer protein TrbE | - |
| NWT85_RS28435 (NWT85_28435) | 96540..96788 | + | 249 | WP_004152675.1 | hypothetical protein | - |
| NWT85_RS28440 (NWT85_28440) | 96801..97127 | + | 327 | WP_085551874.1 | hypothetical protein | - |
| NWT85_RS28445 (NWT85_28445) | 97148..97900 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NWT85_RS28450 (NWT85_28450) | 97911..98150 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NWT85_RS28455 (NWT85_28455) | 98122..98679 | + | 558 | WP_023284641.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NWT85_RS28460 (NWT85_28460) | 98725..99168 | + | 444 | WP_023284642.1 | F-type conjugal transfer protein TrbF | - |
| NWT85_RS28465 (NWT85_28465) | 99146..100525 | + | 1380 | WP_164979616.1 | conjugal transfer pilus assembly protein TraH | - |
| NWT85_RS28470 (NWT85_28470) | 100525..103368 | + | 2844 | WP_064291680.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NWT85_RS28475 (NWT85_28475) | 103379..103903 | + | 525 | WP_015065538.1 | hypothetical protein | - |
| NWT85_RS28480 (NWT85_28480) | 104212..104943 | + | 732 | WP_013023830.1 | conjugal transfer complement resistance protein TraT | - |
| NWT85_RS28485 (NWT85_28485) | 105136..105825 | + | 690 | WP_251892451.1 | hypothetical protein | - |
| NWT85_RS28490 (NWT85_28490) | 105952..108234 | + | 2283 | WP_110133658.1 | type IV conjugative transfer system coupling protein TraD | - |
| NWT85_RS28495 (NWT85_28495) | 108234..113492 | + | 5259 | WP_258335063.1 | Multifunctional conjugation protein TraI | Relaxase |
| NWT85_RS28500 (NWT85_28500) | 113572..114297 | + | 726 | WP_015065543.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| NWT85_RS28505 (NWT85_28505) | 114369..114962 | + | 594 | WP_004152380.1 | fertility inhibition protein FinO | - |
| NWT85_RS28510 (NWT85_28510) | 115123..115725 | + | 603 | WP_179207369.1 | PIN domain-containing protein | - |
| NWT85_RS28515 (NWT85_28515) | 115775..116419 | + | 645 | WP_087652783.1 | hypothetical protein | - |
| NWT85_RS28520 (NWT85_28520) | 116475..117125 | + | 651 | WP_258335064.1 | DUF2726 domain-containing protein | - |
| NWT85_RS28525 (NWT85_28525) | 117122..117430 | + | 309 | WP_004152383.1 | hypothetical protein | - |
| NWT85_RS28530 (NWT85_28530) | 117534..118085 | + | 552 | WP_087652786.1 | Phospholipase D | VF |
| NWT85_RS28535 (NWT85_28535) | 118221..118490 | + | 270 | WP_022631531.1 | replication regulatory protein RepA | - |
| NWT85_RS28540 (NWT85_28540) | 118573..118747 | + | 175 | Protein_140 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|