MGE detailed information

MGE type: Conjugative plasmid        MGE length: 137567 bp
Accession: NZ_CP102079        Location: 1..137567         Organism: Klebsiella pneumoniae strain 5589       Replicon: plasmid p5589-mcr-8


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOV87_RS27160 (NOV87_27160) 1..858 + 858 WP_013023768.1 incFII family plasmid replication initiator RepA -
NOV87_RS27165 (NOV87_27165) 2050..3231 - 1182 WP_013023770.1 DUF4268 domain-containing protein -
NOV87_RS27170 (NOV87_27170) 3514..3663 - 150 Protein_2 IS110 family transposase -
NOV87_RS27175 (NOV87_27175) 3719..3886 - 168 Protein_3 IS5 family transposase IS903 Transposase
NOV87_RS27180 (NOV87_27180) 4022..4291 + 270 Protein_4 SOS response-associated peptidase family protein -
NOV87_RS27185 (NOV87_27185) 4470..4793 + 324 WP_017899891.1 hypothetical protein -
NOV87_RS27190 (NOV87_27190) 5034..5810 + 777 WP_013609504.1 DUF2971 domain-containing protein -
NOV87_RS27195 (NOV87_27195) 6049..6162 + 114 Protein_7 phosphoenolpyruvate hydrolase family protein -
NOV87_RS27200 (NOV87_27200) 6183..7547 + 1365 WP_158192059.1 serine hydrolase domain-containing protein -
NOV87_RS27205 (NOV87_27205) 7834..8304 - 471 WP_072310984.1 GyrI-like domain-containing protein -
NOV87_RS27210 (NOV87_27210) 8901..9707 + 807 WP_072310988.1 MipA/OmpV family protein -
NOV87_RS27215 (NOV87_27215) 9716..10807 + 1092 WP_223349403.1 serine hydrolase domain-containing protein -
NOV87_RS27220 (NOV87_27220) 10827..11183 + 357 WP_072310983.1 hypothetical protein -
NOV87_RS27225 (NOV87_27225) 11207..11740 + 534 WP_072310982.1 hypothetical protein -
NOV87_RS27230 (NOV87_27230) 11742..11951 + 210 WP_072310981.1 helix-turn-helix transcriptional regulator -
NOV87_RS27235 (NOV87_27235) 12149..13048 + 900 WP_118842312.1 hypothetical protein VF
NOV87_RS27240 (NOV87_27240) 13496..13885 - 390 WP_118842310.1 diacylglycerol kinase -
NOV87_RS27245 (NOV87_27245) 13999..15228 - 1230 WP_072310978.1 HAMP domain-containing sensor histidine kinase -
NOV87_RS27250 (NOV87_27250) 15250..15945 - 696 WP_072310977.1 Transcriptional activator protein CopR VF
NOV87_RS27255 (NOV87_27255) 16045..17742 + 1698 WP_114699275.1 phosphoethanolamine--lipid A transferase MCR-8.1 VF
NOV87_RS27260 (NOV87_27260) 17849..18739 + 891 WP_118842309.1 hypothetical protein VF
NOV87_RS27265 (NOV87_27265) 18984..19493 + 510 WP_032445709.1 GNAT family N-acetyltransferase -
NOV87_RS27270 (NOV87_27270) 20432..21130 - 699 WP_032445707.1 DJ-1/PfpI family protein -
NOV87_RS27275 (NOV87_27275) 21420..21770 - 351 WP_223349401.1 hypothetical protein -
NOV87_RS27280 (NOV87_27280) 21827..22030 - 204 WP_072010199.1 hemolysin expression modulator Hha -
NOV87_RS27285 (NOV87_27285) 22102..23070 + 969 WP_256946455.1 IS5 family transposase IS903 Transposase
NOV87_RS27290 (NOV87_27290) 23542..24333 - 792 WP_221928726.1 ribbon-helix-helix domain-containing protein -
NOV87_RS27295 (NOV87_27295) 24516..25544 - 1029 WP_032445668.1 Abi family protein -
NOV87_RS27300 (NOV87_27300) 25705..26286 - 582 WP_072310991.1 hypothetical protein -
NOV87_RS27305 (NOV87_27305) 26855..27073 + 219 WP_001568025.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
NOV87_RS27310 (NOV87_27310) 27075..27380 + 306 WP_013023785.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
NOV87_RS27315 (NOV87_27315) 27549..27944 + 396 WP_017899885.1 hypothetical protein -
NOV87_RS27320 (NOV87_27320) 27971..28294 + 324 WP_004197641.1 hypothetical protein -
NOV87_RS27325 (NOV87_27325) 28291..29307 + 1017 WP_118842534.1 hypothetical protein -
NOV87_RS27330 (NOV87_27330) 29505..30290 + 786 WP_046664219.1 site-specific integrase -
NOV87_RS27335 (NOV87_27335) 30739..31494 + 756 WP_001568031.1 replication initiation protein RepE -
NOV87_RS27340 (NOV87_27340) 32479..33111 + 633 WP_017901447.1 ParA family protein -
NOV87_RS27345 (NOV87_27345) 33111..33485 + 375 WP_017901448.1 hypothetical protein -
NOV87_RS27350 (NOV87_27350) 33725..34699 + 975 WP_020801689.1 plasmid segregation protein ParM -
NOV87_RS27355 (NOV87_27355) 34703..35095 + 393 WP_256946456.1 plasmid partitioning/stability family protein -
NOV87_RS27360 (NOV87_27360) 35665..35886 - 222 WP_046664217.1 helix-turn-helix domain-containing protein -
NOV87_RS27365 (NOV87_27365) 35917..36363 - 447 WP_046664216.1 hypothetical protein -
NOV87_RS27370 (NOV87_27370) 36634..36939 - 306 WP_172691974.1 hypothetical protein -
NOV87_RS27375 (NOV87_27375) 36993..37244 - 252 WP_047368872.1 plasmid stabilization protein -
NOV87_RS27380 (NOV87_27380) 37323..38450 - 1128 Protein_44 translesion error-prone DNA polymerase V subunit UmuC -
NOV87_RS27385 (NOV87_27385) 38527..39534 + 1008 WP_064181645.1 Tyrosine recombinase XerC VF
NOV87_RS27390 (NOV87_27390) 39518..41728 + 2211 WP_032447056.1 tyrosine-type recombinase/integrase -
NOV87_RS27395 (NOV87_27395) 41768..42286 - 519 WP_014839975.1 hypothetical protein -
NOV87_RS27400 (NOV87_27400) 42294..43154 - 861 WP_017900684.1 WYL domain-containing protein -
NOV87_RS27405 (NOV87_27405) 43291..44472 + 1182 WP_017900685.1 hypothetical protein -
NOV87_RS27410 (NOV87_27410) 44469..46697 + 2229 WP_014839974.1 Mov34/MPN/PAD-1 family protein -
NOV87_RS27415 (NOV87_27415) 46742..46870 - 129 Protein_51 DNA polymerase V subunit UmuC -
NOV87_RS27420 (NOV87_27420) 46870..47295 - 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
NOV87_RS27425 (NOV87_27425) 47698..49185 + 1488 WP_161952885.1 hypothetical protein VF
NOV87_RS27430 (NOV87_27430) 49419..49649 + 231 WP_004206779.1 hypothetical protein -
NOV87_RS27435 (NOV87_27435) 50170..50595 + 426 WP_186920192.1 antirestriction protein -
NOV87_RS27440 (NOV87_27440) 50831..51085 + 255 WP_049139361.1 DNA polymerase III subunit theta -
NOV87_RS27445 (NOV87_27445) 51120..51437 + 318 WP_004118473.1 hypothetical protein -
NOV87_RS27450 (NOV87_27450) 52219..52446 + 228 WP_020803451.1 hypothetical protein -
NOV87_RS27455 (NOV87_27455) 52538..52768 + 231 WP_001568051.1 hypothetical protein -
NOV87_RS27460 (NOV87_27460) 52820..54175 + 1356 WP_046664187.1 DUF3560 domain-containing protein -
NOV87_RS27465 (NOV87_27465) 54223..54786 + 564 WP_004152756.1 methyltransferase -
NOV87_RS27470 (NOV87_27470) 55616..56158 + 543 WP_015344994.1 single-stranded DNA-binding protein -
NOV87_RS27475 (NOV87_27475) 56207..56455 + 249 WP_001568055.1 DUF905 domain-containing protein -
NOV87_RS27480 (NOV87_27480) 56525..58582 + 2058 WP_013023805.1 ParB/RepB/Spo0J family partition protein -
NOV87_RS27485 (NOV87_27485) 58627..59058 + 432 WP_013023806.1 conjugation system SOS inhibitor PsiB -
NOV87_RS27490 (NOV87_27490) 59055..59783 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
NOV87_RS27495 (NOV87_27495) 59780..60106 + 327 WP_013023807.1 hypothetical protein -
NOV87_RS27500 (NOV87_27500) 60162..60536 + 375 WP_047665807.1 hypothetical protein -
NOV87_RS27505 (NOV87_27505) 60706..60855 + 150 Protein_69 FlmC family protein -
NOV87_RS27510 (NOV87_27510) 60806..60922 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
NOV87_RS27515 (NOV87_27515) 61615..61887 + 273 WP_014343506.1 hypothetical protein -
NOV87_RS27520 (NOV87_27520) 61884..62234 + 351 WP_013023809.1 hypothetical protein -
NOV87_RS27525 (NOV87_27525) 62249..62566 + 318 WP_013023810.1 hypothetical protein -
NOV87_RS27530 (NOV87_27530) 63408..63764 + 357 WP_013023814.1 hypothetical protein -
NOV87_RS27535 (NOV87_27535) 63825..64037 + 213 WP_013023815.1 hypothetical protein -
NOV87_RS27540 (NOV87_27540) 64048..64272 + 225 WP_004152719.1 hypothetical protein -
NOV87_RS27545 (NOV87_27545) 64353..64673 + 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
NOV87_RS27550 (NOV87_27550) 64663..64941 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
NOV87_RS27555 (NOV87_27555) 64942..65355 + 414 WP_013023817.1 helix-turn-helix domain-containing protein -
NOV87_RS27560 (NOV87_27560) 65491..66699 - 1209 WP_015344990.1 IS256 family transposase ISEic2 Transposase
NOV87_RS27565 (NOV87_27565) 67507..68328 + 822 WP_004152492.1 DUF932 domain-containing protein -
NOV87_RS27570 (NOV87_27570) 68361..68690 + 330 WP_011977736.1 DUF5983 family protein -
NOV87_RS27575 (NOV87_27575) 68723..69208 - 486 WP_001568108.1 hypothetical protein VF
NOV87_RS27580 (NOV87_27580) 69640..70032 + 393 WP_004194114.1 conjugal transfer relaxosome DNA-binding protein TraM -
NOV87_RS27585 (NOV87_27585) 70262..70963 + 702 WP_004194113.1 hypothetical protein -
NOV87_RS27590 (NOV87_27590) 71049..71249 + 201 WP_004194116.1 TraY domain-containing protein -
NOV87_RS27595 (NOV87_27595) 71318..71686 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
NOV87_RS27600 (NOV87_27600) 71700..72005 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
NOV87_RS27605 (NOV87_27605) 72025..72591 + 567 WP_004144423.1 type IV conjugative transfer system protein TraE -
NOV87_RS27610 (NOV87_27610) 72578..73318 + 741 WP_013023821.1 type-F conjugative transfer system secretin TraK -
NOV87_RS27615 (NOV87_27615) 73318..74742 + 1425 WP_004194260.1 F-type conjugal transfer pilus assembly protein TraB -
NOV87_RS27620 (NOV87_27620) 74856..75440 + 585 WP_013023822.1 type IV conjugative transfer system lipoprotein TraV -
NOV87_RS27625 (NOV87_27625) 75572..75982 + 411 WP_009309869.1 hypothetical protein -
NOV87_RS27630 (NOV87_27630) 76088..76306 + 219 WP_015344987.1 hypothetical protein -
NOV87_RS27635 (NOV87_27635) 76307..76618 + 312 WP_015344986.1 hypothetical protein -
NOV87_RS27640 (NOV87_27640) 76685..77089 + 405 WP_004197817.1 hypothetical protein -
NOV87_RS27645 (NOV87_27645) 77465..77863 + 399 WP_013609531.1 hypothetical protein -
NOV87_RS27650 (NOV87_27650) 77935..80574 + 2640 WP_013023824.1 type IV secretion system protein TraC -
NOV87_RS27655 (NOV87_27655) 80574..80963 + 390 WP_004197815.1 type-F conjugative transfer system protein TrbI -
NOV87_RS27660 (NOV87_27660) 80963..81589 + 627 WP_009309871.1 type-F conjugative transfer system protein TraW -
NOV87_RS27665 (NOV87_27665) 81631..82020 + 390 WP_004194992.1 hypothetical protein -
NOV87_RS27670 (NOV87_27670) 82017..83006 + 990 WP_009309872.1 conjugal transfer pilus assembly protein TraU -
NOV87_RS27675 (NOV87_27675) 83019..83657 + 639 WP_015065635.1 type-F conjugative transfer system pilin assembly protein TrbC -
NOV87_RS27680 (NOV87_27680) 83716..85671 + 1956 WP_172691973.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
NOV87_RS27685 (NOV87_27685) 85703..85939 + 237 WP_114499720.1 conjugal transfer protein TrbE -
NOV87_RS27690 (NOV87_27690) 86167..86493 + 327 WP_016529362.1 hypothetical protein -
NOV87_RS27695 (NOV87_27695) 86514..87266 + 753 WP_172691972.1 type-F conjugative transfer system pilin assembly protein TraF -
NOV87_RS27700 (NOV87_27700) 87277..87516 + 240 WP_009309875.1 type-F conjugative transfer system pilin chaperone TraQ -
NOV87_RS27705 (NOV87_27705) 87488..88045 + 558 WP_172691971.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
NOV87_RS27710 (NOV87_27710) 88092..88538 + 447 WP_172691970.1 conjugal transfer protein TrbF -
NOV87_RS27715 (NOV87_27715) 88528..89895 + 1368 WP_185775342.1 conjugal transfer pilus assembly protein TraH -
NOV87_RS27720 (NOV87_27720) 89895..92744 + 2850 WP_172691976.1 conjugal transfer mating-pair stabilization protein TraG -
NOV87_RS27725 (NOV87_27725) 92750..93277 + 528 WP_040120388.1 conjugal transfer protein TraS -
NOV87_RS27730 (NOV87_27730) 93466..94197 + 732 WP_004152629.1 conjugal transfer complement resistance protein TraT -
NOV87_RS27735 (NOV87_27735) 94390..95079 + 690 WP_172691968.1 hypothetical protein -
NOV87_RS27740 (NOV87_27740) 95206..97518 + 2313 WP_228303505.1 type IV conjugative transfer system coupling protein TraD -
NOV87_RS27745 (NOV87_27745) 97518..102776 + 5259 WP_256946452.1 Multifunctional conjugation protein TraI Relaxase
NOV87_RS27750 (NOV87_27750) 102856..103581 + 726 WP_015065543.1 type-F conjugative transfer system pilin acetylase TraX -
NOV87_RS27755 (NOV87_27755) 103653..104246 + 594 WP_172691964.1 fertility inhibition protein FinO -
NOV87_RS27760 (NOV87_27760) 104407..105009 + 603 WP_013023836.1 PIN domain-containing protein -
NOV87_RS27765 (NOV87_27765) 105059..105703 + 645 WP_256946453.1 hypothetical protein -
NOV87_RS27770 (NOV87_27770) 105759..106409 + 651 WP_014343480.1 DUF2726 domain-containing protein -
NOV87_RS27775 (NOV87_27775) 106406..106714 + 309 WP_004152383.1 hypothetical protein -
NOV87_RS27780 (NOV87_27780) 106902..107606 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
NOV87_RS27785 (NOV87_27785) 107659..108006 + 348 Protein_125 bleomycin binding protein -
NOV87_RS27790 (NOV87_27790) 108326..108718 - 393 WP_000084745.1 pyridoxamine 5'-phosphate oxidase family protein -
NOV87_RS27795 (NOV87_27795) 109053..109757 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
NOV87_RS27800 (NOV87_27800) 109873..112410 + 2538 Protein_128 Tn3 family transposase TnpA_Tn3 Transposase
NOV87_RS27805 (NOV87_27805) 112505..113140 + 636 WP_001253263.1 DUF3363 domain-containing protein -
NOV87_RS27810 (NOV87_27810) 113357..114571 + 1215 WP_000214121.1 Bicyclomycin resistance protein ARG
NOV87_RS27815 (NOV87_27815) 114599..114904 + 306 WP_001255015.1 HTH-type transcriptional regulator HdfR VF
NOV87_RS27820 (NOV87_27820) 115016..115204 + 189 Protein_132 IS91 family transposase -
NOV87_RS27825 (NOV87_27825) 115171..116370 - 1200 WP_000804063.1 Tetracycline resistance protein, class C ARG
NOV87_RS27830 (NOV87_27830) 116476..117126 + 651 WP_000164043.1 tetracycline resistance transcriptional repressor TetR(A) -
NOV87_RS27835 (NOV87_27835) 117158..117400 - 243 WP_000844627.1 transposase -
NOV87_RS27840 (NOV87_27840) 117601..118305 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NOV87_RS27845 (NOV87_27845) 118427..119332 + 906 WP_000219391.1 hypothetical protein ARG
NOV87_RS27850 (NOV87_27850) 119329..120567 + 1239 WP_000004159.1 macrolide resistance MFS transporter Mrx(A) -
NOV87_RS27855 (NOV87_27855) 120567..121151 + 585 WP_001137892.1 macrolide-binding transcriptional repressor MphR(A) -
NOV87_RS27860 (NOV87_27860) 121644..122408 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
NOV87_RS27865 (NOV87_27865) 122526..122594 - 69 Protein_141 EAL domain-containing protein -
NOV87_RS27870 (NOV87_27870) 122915..123415 - 501 WP_000376623.1 GNAT family N-acetyltransferase -
NOV87_RS27875 (NOV87_27875) 123543..124382 - 840 WP_000259031.1 Dihydropteroate synthase ARG
NOV87_RS27880 (NOV87_27880) 124376..124579 - 204 Protein_144 SMR family transporter -
NOV87_RS27885 (NOV87_27885) 124571..124777 + 207 Protein_145 phage shock protein operon transcriptional activator -
NOV87_RS27890 (NOV87_27890) 124873..125517 + 645 WP_065908739.1 Pentapeptide repeat protein ARG
NOV87_RS27895 (NOV87_27895) 125559..126011 - 453 WP_003833285.1 SgcJ/EcaC family oxidoreductase -
NOV87_RS27900 (NOV87_27900) 126546..127085 + 540 Protein_148 ABC transporter substrate-binding protein -
NOV87_RS27905 (NOV87_27905) 127318..128859 - 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
NOV87_RS27910 (NOV87_27910) 129264..130103 - 840 WP_000259031.1 Dihydropteroate synthase ARG
NOV87_RS27915 (NOV87_27915) 130097..130444 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
NOV87_RS27920 (NOV87_27920) 130561..131406 - 846 WP_001749984.1 Streptomycin 3''-adenylyltransferase ARG
NOV87_RS27925 (NOV87_27925) 131587..132060 - 474 WP_001749985.1 Dihydrofolate reductase type 1 ARG
NOV87_RS27930 (NOV87_27930) 132193..132645 - 453 WP_001749986.1 hypothetical protein ARG
NOV87_RS27935 (NOV87_27935) 132742..133296 - 555 WP_063840321.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
NOV87_RS27940 (NOV87_27940) 133588..134601 + 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
NOV87_RS27945 (NOV87_27945) 135072..135776 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
NOV87_RS27950 (NOV87_27950) 135753..136196 + 444 WP_256946454.1 hypothetical protein -
NOV87_RS27955 (NOV87_27955) 136370..136879 + 510 WP_052145515.1 Phospholipase D VF
NOV87_RS27960 (NOV87_27960) 136997..137266 + 270 WP_013609506.1 replication regulatory protein RepA -
NOV87_RS27965 (NOV87_27965) 137381..137555 + 175 Protein_161 protein CopA/IncA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance