MGE detailed information
MGE type: Mobilizable plasmid MGE length: 127176 bp
Accession: NZ_CP101766 Location: 1..127176 Organism: Klebsiella pneumoniae strain hvKP319 Replicon: plasmid unnamed2
Accession: NZ_CP101766 Location: 1..127176 Organism: Klebsiella pneumoniae strain hvKP319 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NPJ83_RS28655 (1) | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| NPJ83_RS28660 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NPJ83_RS28665 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NPJ83_RS28670 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NPJ83_RS28675 (3383) | 3383..3798 | + | 416 | Protein_4 | IS1 family transposase | - |
| NPJ83_RS28680 (3834) | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NPJ83_RS28685 (4445) | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS28690 (5219) | 5219..5410 | + | 192 | Protein_7 | IS1380 family transposase | - |
| NPJ83_RS28695 (5660) | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| NPJ83_RS28700 (6570) | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| NPJ83_RS28705 (7595) | 7595..8692 | + | 1098 | Protein_10 | TonB-dependent receptor | - |
| NPJ83_RS28710 (8760) | 8760..9236 | - | 477 | Protein_11 | PAS domain-containing protein | - |
| NPJ83_RS28715 (9289) | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS28720 (10058) | 10058..10648 | + | 591 | Protein_13 | IS91 family transposase ISSbo1 | Transposase |
| NPJ83_RS28725 (11104) | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS28730 (11859) | 11859..12476 | - | 618 | Protein_15 | IS91 family transposase ISSbo1 | Transposase |
| NPJ83_RS28735 (12486) | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| NPJ83_RS28740 (12766) | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NPJ83_RS28745 (13485) | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NPJ83_RS28750 (14515) | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| NPJ83_RS28755 (15351) | 15351..15665 | - | 315 | Protein_20 | hypothetical protein | - |
| NPJ83_RS28760 (15720) | 15720..16424 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS28765 (16490) | 16490..16555 | + | 66 | Protein_22 | IS1 family transposase | - |
| NPJ83_RS28770 (18004) | 18004..18238 | + | 235 | Protein_23 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NPJ83_RS28775 (18366) | 18366..18647 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| NPJ83_RS28780 (18770) | 18770..19120 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| NPJ83_RS28785 (19123) | 19123..20085 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| NPJ83_RS28790 (20232) | 20232..20525 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| NPJ83_RS28795 (20602) | 20602..21285 | + | 684 | WP_000085883.1 | DNA methylase | - |
| NPJ83_RS28800 (21286) | 21286..21507 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| NPJ83_RS28805 (21521) | 21521..21955 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| NPJ83_RS28810 (22006) | 22006..22782 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| NPJ83_RS28815 (23200) | 23200..23625 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| NPJ83_RS28820 (23672) | 23672..24094 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| NPJ83_RS28825 (24091) | 24091..24282 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| NPJ83_RS28830 (24596) | 24596..26263 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| NPJ83_RS28835 (26992) | 26992..27146 | - | 155 | Protein_36 | hypothetical protein | - |
| NPJ83_RS28840 (27663) | 27663..27893 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| NPJ83_RS28845 (27945) | 27945..29306 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| NPJ83_RS28850 (29353) | 29353..29916 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| NPJ83_RS28855 (30002) | 30002..30457 | - | 456 | Protein_40 | hypothetical protein | - |
| NPJ83_RS28860 (30759) | 30759..31286 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| NPJ83_RS28865 (31344) | 31344..31577 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| NPJ83_RS28870 (31638) | 31638..33661 | + | 2024 | Protein_43 | ParB/RepB/Spo0J family partition protein | - |
| NPJ83_RS28875 (33730) | 33730..34164 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| NPJ83_RS28880 (34161) | 34161..34880 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (34892) | 34892..35116 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| NPJ83_RS28885 (35102) | 35102..35251 | + | 150 | Protein_46 | plasmid maintenance protein Mok | - |
| NPJ83_RS28890 (35193) | 35193..35318 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NPJ83_RS28895 (35637) | 35637..35933 | - | 297 | Protein_48 | hypothetical protein | - |
| NPJ83_RS28900 (36233) | 36233..36529 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| NPJ83_RS28905 (36640) | 36640..37461 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| NPJ83_RS28910 (37758) | 37758..38405 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| NPJ83_RS28915 (38682) | 38682..39065 | + | 384 | WP_000124981.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NPJ83_RS28920 (39346) | 39346..40050 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS28925 (40104) | 40104..40427 | - | 324 | Protein_54 | class II aldolase/adducin family protein | - |
| NPJ83_RS28930 (40420) | 40420..41672 | - | 1253 | Protein_55 | four-carbon acid sugar kinase family protein | - |
| NPJ83_RS28935 (41684) | 41684..42586 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| NPJ83_RS28940 (42848) | 42848..43609 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| NPJ83_RS28945 (43630) | 43630..44490 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| NPJ83_RS28950 (44627) | 44627..44695 | + | 69 | Protein_59 | IS6 family transposase | - |
| NPJ83_RS28955 (44731) | 44731..47697 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NPJ83_RS28960 (47701) | 47701..47898 | - | 198 | Protein_61 | helix-turn-helix domain-containing protein | - |
| NPJ83_RS28965 (47950) | 47950..48654 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS28970 (48719) | 48719..49891 | - | 1173 | Protein_63 | transposase | - |
| NPJ83_RS28975 (49966) | 49966..50634 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| NPJ83_RS28980 (50670) | 50670..50906 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| NPJ83_RS28985 (50903) | 50903..51265 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| NPJ83_RS28990 (51283) | 51283..52977 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| NPJ83_RS28995 (53029) | 53029..53451 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| NPJ83_RS29000 (53487) | 53487..53762 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| NPJ83_RS29005 (53776) | 53776..54126 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| NPJ83_RS29010 (54198) | 54198..54632 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| NPJ83_RS29015 (54711) | 54711..55715 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| NPJ83_RS29020 (56243) | 56243..57643 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| NPJ83_RS29025 (57640) | 57640..58320 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| NPJ83_RS29030 (58375) | 58375..59304 | - | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| NPJ83_RS29035 (59309) | 59309..59689 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| NPJ83_RS29040 (59729) | 59729..60619 | - | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| NPJ83_RS29045 (60625) | 60625..62442 | - | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| NPJ83_RS29050 (62676) | 62676..63143 | + | 468 | WP_048336866.1 | hypothetical protein | - |
| NPJ83_RS29055 (63410) | 63410..64147 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| NPJ83_RS29060 (64181) | 64181..64378 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| NPJ83_RS29065 (64419) | 64419..66866 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| NPJ83_RS29070 (66993) | 66993..67433 | - | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| NPJ83_RS29075 (67520) | 67520..70666 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| NPJ83_RS29080 (70677) | 70677..71969 | - | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| NPJ83_RS29085 (72083) | 72083..72445 | - | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| NPJ83_RS29090 (72474) | 72474..73859 | - | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| NPJ83_RS29095 (74049) | 74049..74729 | + | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| NPJ83_RS29100 (74722) | 74722..76197 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| NPJ83_RS29105 (76448) | 76448..76879 | + | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| NPJ83_RS29110 (77023) | 77023..77373 | + | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| NPJ83_RS29115 (77760) | 77760..78668 | - | 909 | WP_023302803.1 | HNH endonuclease | - |
| NPJ83_RS29120 (79305) | 79305..80279 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| NPJ83_RS29125 (80458) | 80458..80658 | + | 201 | Protein_94 | hypothetical protein | - |
| NPJ83_RS29130 (80864) | 80864..81808 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| NPJ83_RS29135 (81845) | 81845..82237 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| NPJ83_RS29140 (82295) | 82295..82816 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| NPJ83_RS29145 (82862) | 82862..83065 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| NPJ83_RS29150 (83095) | 83095..84099 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| NPJ83_RS29155 (84283) | 84283..85062 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| NPJ83_RS29160 (85108) | 85108..85365 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| NPJ83_RS29165 (85494) | 85494..85607 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| NPJ83_RS29170 (86143) | 86143..87009 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| NPJ83_RS29175 (88119) | 88119..89324 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| NPJ83_RS29180 (89324) | 89324..90298 | + | 975 | WP_011977819.1 | ParB family protein | - |
| NPJ83_RS29185 (90380) | 90380..91651 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| NPJ83_RS29190 (91651) | 91651..92082 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NPJ83_RS29195 (92489) | 92489..93976 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| NPJ83_RS29200 (94225) | 94225..95196 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| NPJ83_RS29205 (95199) | 95199..95870 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| NPJ83_RS29210 (95933) | 95933..96163 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| NPJ83_RS29215 (96359) | 96359..96528 | + | 170 | Protein_112 | hypothetical protein | - |
| NPJ83_RS29220 (96600) | 96600..97301 | + | 702 | WP_001568041.1 | DNA methylase | - |
| NPJ83_RS29225 (97301) | 97301..97522 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| NPJ83_RS29230 (97532) | 97532..97951 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| NPJ83_RS29235 (98005) | 98005..98772 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| NPJ83_RS29240 (99453) | 99453..99881 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| NPJ83_RS29245 (99924) | 99924..100430 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| NPJ83_RS29250 (100473) | 100473..100664 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| NPJ83_RS29255 (100852) | 100852..101106 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| NPJ83_RS29260 (101141) | 101141..101461 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| NPJ83_RS29265 (102141) | 102141..102368 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| NPJ83_RS29270 (102460) | 102460..102690 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| NPJ83_RS29275 (102742) | 102742..104097 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| NPJ83_RS29280 (104145) | 104145..104708 | + | 564 | WP_014343514.1 | methyltransferase | - |
| NPJ83_RS29285 (105541) | 105541..106083 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| NPJ83_RS29290 (106132) | 106132..106380 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| NPJ83_RS29295 (106450) | 106450..108507 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| NPJ83_RS29300 (108552) | 108552..108983 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| NPJ83_RS29305 (108980) | 108980..109708 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| NPJ83_RS29310 (109705) | 109705..110031 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| NPJ83_RS29315 (110087) | 110087..110461 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| NPJ83_RS29320 (110645) | 110645..111718 | - | 1074 | WP_032442619.1 | IS481 family transposase ISKpn28 | Transposase |
| NPJ83_RS29325 (111832) | 111832..111948 | + | 117 | WP_055313929.1 | type I toxin-antitoxin system Hok family toxin | - |
| NPJ83_RS29330 (112641) | 112641..112913 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| NPJ83_RS29335 (112910) | 112910..113260 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| NPJ83_RS29340 (113275) | 113275..113592 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| NPJ83_RS29345 (114433) | 114433..114789 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| NPJ83_RS29350 (114850) | 114850..115062 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| NPJ83_RS29355 (115073) | 115073..115297 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| NPJ83_RS29360 (115378) | 115378..115698 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| NPJ83_RS29365 (115688) | 115688..115966 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| NPJ83_RS29370 (115970) | 115970..116074 | + | 105 | Protein_143 | transcriptional regulator | - |
| NPJ83_RS29375 (116903) | 116903..117724 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| NPJ83_RS29380 (117757) | 117757..118086 | + | 330 | WP_013214015.1 | DUF5983 family protein | - |
| NPJ83_RS29385 (118119) | 118119..118604 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| NPJ83_RS29390 (118995) | 118995..119411 | + | 417 | WP_014343494.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NPJ83_RS29395 (119611) | 119611..120348 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| NPJ83_RS29400 (120463) | 120463..120669 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| NPJ83_RS29405 (120731) | 120731..121099 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| NPJ83_RS29410 (121113) | 121113..121418 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| NPJ83_RS29415 (121438) | 121438..121803 | + | 366 | Protein_152 | type IV conjugative transfer system protein TraE | - |
| NPJ83_RS29420 (121858) | 121858..122562 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NPJ83_RS29425 (122587) | 122587..122787 | + | 201 | WP_072354025.1 | hypothetical protein | - |
| NPJ83_RS29430 (122807) | 122807..123553 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| NPJ83_RS29435 (123608) | 123608..124168 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| NPJ83_RS29440 (124300) | 124300..124500 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| NPJ83_RS29445 (124886) | 124886..125485 | + | 600 | WP_032083981.1 | PIN domain-containing protein | - |
| NPJ83_RS29450 (125547) | 125547..125879 | + | 333 | WP_152916585.1 | hypothetical protein | - |
| - (126080) | 126080..126139 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (126080) | 126080..126139 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (126080) | 126080..126139 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (126080) | 126080..126139 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| NPJ83_RS29455 (126184) | 126184..126333 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| NPJ83_RS29460 (126617) | 126617..126865 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
| NPJ83_RS29465 (126980) | 126980..127164 | + | 185 | Protein_162 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|