MGE detailed information
MGE type: Conjugative plasmid MGE length: 111893 bp
Accession: NZ_CP101276 Location: 1..111893 Organism: Escherichia coli strain EC21Z-014 Replicon: plasmid pEC21Z014-112K
Accession: NZ_CP101276 Location: 1..111893 Organism: Escherichia coli strain EC21Z-014 Replicon: plasmid pEC21Z014-112K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML17_RS24715 () | 1..858 | + | 858 | WP_065800511.1 | incFII family plasmid replication initiator RepA | - |
| NML17_RS24720 () | 1559..1699 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| NML17_RS24725 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NML17_RS24730 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NML17_RS24735 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NML17_RS24740 () | 3419..4729 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| NML17_RS24745 () | 4758..4856 | + | 99 | Protein_6 | IS1 family transposase | - |
| NML17_RS24750 () | 5006..5866 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NML17_RS24755 () | 6169..6873 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NML17_RS24760 () | 6925..7269 | + | 345 | Protein_9 | IS6 family transposase IS15DI | Transposase |
| NML17_RS24765 () | 7334..7564 | + | 231 | Protein_10 | transposase family protein | - |
| NML17_RS24770 () | 7573..8433 | + | 861 | WP_000493383.1 | EamA family transporter | - |
| NML17_RS24775 () | 8465..9664 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| NML17_RS24780 () | 9770..10420 | + | 651 | WP_038989485.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| NML17_RS24785 () | 10452..10688 | - | 237 | WP_042005022.1 | hypothetical protein | - |
| NML17_RS24790 () | 10742..11578 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| NML17_RS24795 () | 11578..12381 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| NML17_RS24800 () | 12442..13257 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| NML17_RS24805 () | 13565..13741 | - | 177 | Protein_18 | replication protein C | - |
| NML17_RS24810 () | 13802..14506 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| NML17_RS24815 () | 14628..15533 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| NML17_RS24820 () | 15530..16768 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| NML17_RS24825 () | 16768..17352 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| NML17_RS24830 () | 17845..18609 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| NML17_RS24835 () | 18727..18792 | - | 66 | Protein_24 | EAL domain-containing protein | - |
| NML17_RS24840 () | 18812..19162 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| NML17_RS24845 () | 19365..20378 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| NML17_RS24850 () | 20536..21009 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| NML17_RS24855 () | 21140..21928 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| NML17_RS24860 () | 22134..22481 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NML17_RS24865 () | 22475..23314 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| NML17_RS24870 () | 23442..23645 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| NML17_RS24875 () | 23775..24479 | - | 705 | WP_073520228.1 | IS6 family transposase IS15DI | Transposase |
| NML17_RS24880 () | 24544..24900 | + | 357 | Protein_33 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| NML17_RS24885 () | 24903..27869 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NML17_RS24890 () | 27878..28294 | + | 417 | WP_031610367.1 | hypothetical protein | - |
| NML17_RS24895 () | 28771..29037 | - | 267 | WP_000627831.1 | hypothetical protein | - |
| NML17_RS24900 () | 29037..29531 | - | 495 | WP_001442119.1 | hypothetical protein | - |
| NML17_RS24905 () | 29587..30189 | - | 603 | WP_000517689.1 | ProQ/FINO family protein | - |
| NML17_RS24910 () | 30543..31889 | + | 1347 | WP_001132019.1 | protein YagA | - |
| NML17_RS24915 () | 32168..34048 | + | 1881 | WP_254815540.1 | colicin Ia central receptor-binding domain-containing protein | - |
| NML17_RS24920 () | 34066..34413 | - | 348 | WP_000762580.1 | colicin E1 family microcin immunity protein | - |
| NML17_RS24925 () | 34532..34879 | + | 348 | WP_000142424.1 | DUF6404 family protein | - |
| NML17_RS24930 () | 34897..35487 | - | 591 | WP_000194555.1 | hypothetical protein | - |
| NML17_RS24935 () | 35484..35744 | - | 261 | WP_000343102.1 | hypothetical protein | - |
| NML17_RS24940 () | 36073..36525 | + | 453 | WP_000670961.1 | dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase | VF |
| NML17_RS24945 () | 36558..38090 | - | 1533 | WP_001017348.1 | NAD(P)-binding domain-containing protein | - |
| NML17_RS24950 () | 38087..38356 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| NML17_RS24955 () | 38358..39374 | - | 1017 | WP_016230896.1 | Gfo/Idh/MocA family oxidoreductase | - |
| NML17_RS24960 () | 39374..40204 | - | 831 | WP_016230897.1 | HAD-IIB family hydrolase | - |
| NML17_RS24965 () | 40188..41426 | - | 1239 | WP_024188128.1 | 3-oxo-glucose-6-phosphate:glutamate aminotransferase | VF |
| NML17_RS24970 () | 42272..42490 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| NML17_RS24975 () | 42492..42797 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| NML17_RS24980 () | 42798..43607 | + | 810 | WP_021514797.1 | site-specific integrase | - |
| NML17_RS24985 () | 43780..44133 | + | 354 | WP_000864812.1 | colicin M immunity protein | - |
| NML17_RS24990 () | 44183..44998 | - | 816 | WP_000449473.1 | lipid II-degrading bacteriocin colicin M | - |
| NML17_RS24995 () | 45241..45768 | + | 528 | WP_000203268.1 | colicin B immunity protein | - |
| NML17_RS25000 () | 45786..47321 | - | 1536 | WP_001282376.1 | pore-forming bacteriocin colicin B | - |
| NML17_RS25005 () | 47762..48274 | + | 513 | WP_001027529.1 | hypothetical protein | - |
| NML17_RS25010 () | 48425..48775 | - | 351 | WP_000361384.1 | plasmid partitioning/stability family protein | - |
| NML17_RS25015 () | 48778..49740 | - | 963 | WP_000959880.1 | plasmid segregation protein ParM | - |
| NML17_RS25020 () | 49888..50181 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| NML17_RS25025 () | 50258..50941 | + | 684 | WP_021514796.1 | DNA methylase | - |
| NML17_RS25030 () | 50942..51163 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| NML17_RS25035 () | 51093..51611 | + | 519 | WP_223174655.1 | DUF1380 family protein | - |
| NML17_RS25040 () | 51656..52426 | + | 771 | WP_001006200.1 | hypothetical protein | - |
| NML17_RS25045 () | 52500..53612 | + | 1113 | WP_001300563.1 | IS4 family transposase IS421 | Transposase |
| NML17_RS25050 () | 54188..54613 | + | 426 | WP_021514795.1 | antirestriction protein | - |
| NML17_RS25055 () | 54660..55082 | + | 423 | WP_000271682.1 | DUF1380 family protein | - |
| NML17_RS25060 () | 55079..55270 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| NML17_RS25065 () | 55636..55791 | - | 156 | Protein_70 | hypothetical protein | - |
| NML17_RS25070 () | 56309..56539 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| NML17_RS25075 () | 56591..57952 | + | 1362 | WP_000170702.1 | DUF3560 domain-containing protein | - |
| NML17_RS25080 () | 58000..58563 | + | 564 | WP_001330829.1 | class I SAM-dependent methyltransferase | - |
| NML17_RS25085 () | 58560..58778 | + | 219 | WP_071588970.1 | hypothetical protein | - |
| NML17_RS25090 () | 58715..58948 | + | 234 | WP_071588969.1 | hypothetical protein | - |
| NML17_RS25095 () | 59189..59395 | + | 207 | WP_000547971.1 | hypothetical protein | - |
| NML17_RS25100 () | 59421..59960 | + | 540 | WP_009426937.1 | single-stranded DNA-binding protein | - |
| NML17_RS25105 () | 60022..60255 | + | 234 | WP_000006030.1 | DUF905 family protein | - |
| NML17_RS25110 () | 60320..62284 | + | 1965 | WP_021514794.1 | ParB/RepB/Spo0J family partition protein | - |
| NML17_RS25115 () | 62353..62787 | + | 435 | WP_000845894.1 | conjugation system SOS inhibitor PsiB | - |
| NML17_RS25120 () | 62784..63546 | + | 763 | Protein_81 | plasmid SOS inhibition protein A | - |
| NML17_RS25125 () | 63515..63703 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 63515..63739 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63515..63739 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63515..63739 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 63515..63739 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - | 63672..63737 | - | 66 | - | - | Antitoxin Detail |
| NML17_RS25130 () | 63725..63874 | + | 150 | Protein_83 | plasmid maintenance protein Mok | - |
| NML17_RS25135 () | 63816..63941 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| NML17_RS25140 () | 64161..64391 | + | 231 | WP_071998556.1 | hypothetical protein | - |
| NML17_RS25145 () | 64411..64548 | - | 138 | Protein_86 | hypothetical protein | - |
| NML17_RS25150 () | 64618..64824 | + | 207 | WP_032192990.1 | hypothetical protein | - |
| NML17_RS25155 () | 64849..65136 | + | 288 | WP_000107542.1 | hypothetical protein | - |
| NML17_RS25160 () | 65255..66076 | + | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| NML17_RS25165 () | 66373..67020 | - | 648 | WP_139242155.1 | hypothetical protein | VF |
| NML17_RS25170 () | 67306..67689 | + | 384 | WP_001151564.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| NML17_RS25175 () | 67883..68569 | + | 687 | WP_072652392.1 | PAS domain-containing protein | - |
| NML17_RS25180 () | 68663..68890 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| NML17_RS25185 () | 68924..69283 | + | 360 | WP_254815538.1 | type IV conjugative transfer system pilin TraA | - |
| NML17_RS25190 () | 69298..69609 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NML17_RS25195 () | 69631..70197 | + | 567 | WP_000399805.1 | type IV conjugative transfer system protein TraE | - |
| NML17_RS25200 () | 70184..70912 | + | 729 | WP_001230809.1 | type-F conjugative transfer system secretin TraK | - |
| NML17_RS25205 () | 70912..72363 | + | 1452 | WP_254815539.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| NML17_RS25210 () | 72353..72919 | + | 567 | WP_045146963.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| NML17_RS25215 () | 72906..73226 | + | 321 | WP_021514862.1 | conjugal transfer protein TrbD | - |
| NML17_RS25220 () | 73219..73470 | + | 252 | WP_001038348.1 | conjugal transfer protein TrbG | - |
| NML17_RS25225 () | 73467..73982 | + | 516 | WP_021514860.1 | type IV conjugative transfer system lipoprotein TraV | - |
| NML17_RS25230 () | 74117..74338 | + | 222 | WP_001278695.1 | conjugal transfer protein TraR | - |
| NML17_RS25235 () | 74331..74807 | + | 477 | WP_000549580.1 | hypothetical protein | - |
| NML17_RS25240 () | 74887..75102 | + | 216 | WP_000556747.1 | hypothetical protein | - |
| NML17_RS25245 () | 75130..75348 | + | 219 | Protein_106 | hypothetical protein | - |
| NML17_RS25250 () | 75419..76399 | + | 981 | WP_021539078.1 | IS5 family transposase ISKpn26 | Transposase |
| NML17_RS25255 () | 76817..79447 | + | 2631 | WP_064558378.1 | type IV secretion system protein TraC | - |
| NML17_RS25260 () | 79444..79830 | + | 387 | WP_021536235.1 | type-F conjugative transfer system protein TrbI | - |
| NML17_RS25265 () | 79827..80459 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| NML17_RS25270 () | 80456..81448 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| NML17_RS25275 () | 81469..81648 | + | 180 | WP_032193743.1 | hypothetical protein | - |
| NML17_RS25280 () | 82077..82715 | + | 639 | WP_021514850.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| NML17_RS25285 () | 82712..83083 | + | 372 | WP_021514849.1 | hypothetical protein | - |
| NML17_RS25290 () | 83108..83530 | + | 423 | WP_001229306.1 | HNH endonuclease signature motif containing protein | - |
| NML17_RS25295 () | 83527..85377 | + | 1851 | WP_021537336.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| NML17_RS25300 () | 85404..85661 | + | 258 | WP_000864341.1 | conjugal transfer protein TrbE | - |
| NML17_RS25305 () | 85654..86397 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| NML17_RS25310 () | 86558..86794 | + | 237 | WP_001346259.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| NML17_RS25315 () | 86781..87326 | + | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| NML17_RS25320 () | 87256..87618 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| NML17_RS25325 () | 87618..88991 | + | 1374 | WP_001137358.1 | conjugal transfer pilus assembly protein TraH | - |
| NML17_RS25330 () | 88988..91810 | + | 2823 | WP_053320755.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| NML17_RS25335 () | 91825..92328 | + | 504 | WP_053320762.1 | surface exclusion protein | - |
| NML17_RS25340 () | 92381..93091 | + | 711 | WP_231793510.1 | conjugal transfer complement resistance protein TraT | - |
| NML17_RS25345 () | 93344..95560 | + | 2217 | WP_065813483.1 | type IV conjugative transfer system coupling protein TraD | - |
| NML17_RS25350 () | 95560..100830 | + | 5271 | WP_053320757.1 | Multifunctional conjugation protein TraI | Relaxase |
| NML17_RS25355 () | 100850..101593 | + | 744 | WP_000205704.1 | conjugal transfer pilus acetylase TraX | - |
| NML17_RS25360 () | 101648..102208 | + | 561 | WP_024184455.1 | fertility inhibition protein FinO | - |
| NML17_RS25365 () | 102344..102556 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| NML17_RS25370 () | 102651..102839 | + | 189 | WP_001137617.1 | hypothetical protein | - |
| NML17_RS25375 () | 102842..105391 | + | 2550 | WP_053320758.1 | DEAD/DEAH box helicase family protein | - |
| NML17_RS25380 () | 105437..107470 | + | 2034 | WP_000887497.1 | N-6 DNA methylase | - |
| NML17_RS25385 () | 107535..110390 | + | 2856 | WP_053320759.1 | chromosome segregation protein SMC | - |
| NML17_RS25390 () | 110968..111092 | + | 125 | Protein_135 | hypothetical protein | - |
| NML17_RS25395 () | 111332..111592 | + | 261 | WP_000078108.1 | replication regulatory protein RepA | - |
| NML17_RS25400 () | 111696..111881 | + | 186 | Protein_137 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|