MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 109419 bp
Accession: NZ_CP101264 Location: 1..109419 Organism: Escherichia coli strain EC21Z-063 Replicon: plasmid pEC21Z063-110K-NDM5
Accession: NZ_CP101264 Location: 1..109419 Organism: Escherichia coli strain EC21Z-063 Replicon: plasmid pEC21Z063-110K-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML19_RS22935 (NML19_22930) | 2..754 | + | 753 | Protein_1 | plasmid replication initiator TrfA | - |
| NML19_RS22940 (NML19_22935) | 1876..2256 | + | 381 | WP_012006610.1 | hypothetical protein | - |
| NML19_RS22945 (NML19_22940) | 2307..2624 | + | 318 | WP_000043357.1 | type IV conjugative transfer system protein TraL | - |
| NML19_RS22950 (NML19_22945) | 2636..3424 | + | 789 | WP_000783153.1 | TraE/TraK family type IV conjugative transfer system protein | - |
| NML19_RS22955 (NML19_22950) | 3424..4695 | + | 1272 | WP_000592090.1 | type-F conjugative transfer system secretin TraK | - |
| NML19_RS22960 (NML19_22955) | 4697..5158 | + | 462 | WP_000521240.1 | plasmid transfer protein HtdO | - |
| NML19_RS22965 (NML19_22960) | 5148..6503 | + | 1356 | WP_000351841.1 | IncHI-type conjugal transfer protein TrhB | - |
| NML19_RS22970 (NML19_22965) | 6511..6993 | + | 483 | WP_000377633.1 | hypothetical protein | - |
| NML19_RS22975 (NML19_22970) | 7112..7864 | + | 753 | WP_183079335.1 | protein-disulfide isomerase HtdT | - |
| NML19_RS22980 (NML19_22975) | 7874..8824 | + | 951 | WP_001022587.1 | IncHI-type conjugal transfer lipoprotein TrhV | - |
| NML19_RS22985 (NML19_22980) | 8833..11514 | + | 2682 | WP_000387412.1 | TraC family protein | - |
| NML19_RS22990 (NML19_22985) | 15351..16604 | + | 1254 | WP_032084678.1 | hypothetical protein | VF |
| NML19_RS22995 (NML19_22990) | 16601..17605 | + | 1005 | WP_032192066.1 | ParB family protein | - |
| NML19_RS23000 (NML19_22995) | 17667..18056 | - | 390 | WP_001572421.1 | hypothetical protein | - |
| NML19_RS23005 (NML19_23000) | 18053..18574 | - | 522 | WP_000598516.1 | hypothetical protein | - |
| NML19_RS23010 (NML19_23005) | 18567..19403 | - | 837 | WP_106108369.1 | hypothetical protein | - |
| NML19_RS23015 (NML19_23010) | 19400..20347 | - | 948 | WP_046788422.1 | metallophosphoesterase | - |
| NML19_RS23020 (NML19_23015) | 20711..21748 | + | 1038 | WP_000818955.1 | plasmid segregation protein ParM | - |
| NML19_RS23025 (NML19_23020) | 21760..22398 | + | 639 | WP_001107537.1 | hypothetical protein | - |
| NML19_RS23030 (NML19_23025) | 22886..23254 | + | 369 | WP_015059473.1 | hypothetical protein | - |
| NML19_RS23035 (NML19_23030) | 23244..23669 | + | 426 | WP_000836980.1 | hypothetical protein | - |
| NML19_RS23040 (NML19_23035) | 23678..24232 | + | 555 | WP_000235777.1 | hypothetical protein | - |
| NML19_RS23045 (NML19_23040) | 24352..28656 | + | 4305 | WP_001232107.1 | IncHI-type conjugal transfer protein RSP | - |
| NML19_RS23050 (NML19_23045) | 28934..29446 | + | 513 | WP_001286759.1 | IncHI-type conjugal transfer protein TrhF | - |
| NML19_RS23055 (NML19_23050) | 29433..30944 | + | 1512 | WP_001256133.1 | TrbC family F-type conjugative pilus assembly protein | - |
| NML19_RS23060 (NML19_23055) | 31089..32144 | + | 1056 | WP_181196458.1 | IncHI-type conjugal transfer protein TrhU | - |
| NML19_RS23065 (NML19_23060) | 32163..35351 | + | 3189 | WP_000776705.1 | IncHI-type conjugal transfer protein TrhN | - |
| NML19_RS23070 (NML19_23065) | 35380..36252 | - | 873 | WP_000771832.1 | hypothetical protein | - |
| NML19_RS23075 (NML19_23070) | 36432..38216 | + | 1785 | WP_042634277.1 | IncHI-type conjugal transfer helicase TrhI | - |
| NML19_RS23080 (NML19_23075) | 38611..39483 | + | 873 | WP_000041927.1 | hypothetical protein | - |
| NML19_RS23085 (NML19_23080) | 39541..39918 | + | 378 | WP_000120822.1 | hypothetical protein | - |
| NML19_RS23090 (NML19_23085) | 39979..40956 | + | 978 | WP_042634278.1 | hypothetical protein | - |
| NML19_RS23095 (NML19_23090) | 41014..42072 | + | 1059 | WP_000063335.1 | AAA family ATPase | - |
| NML19_RS23100 (NML19_23095) | 42204..42377 | + | 174 | WP_001176647.1 | hypothetical protein | - |
| NML19_RS23105 (NML19_23100) | 42441..43568 | + | 1128 | WP_000174395.1 | DUF3150 domain-containing protein | - |
| NML19_RS23110 (NML19_23105) | 43646..45658 | + | 2013 | WP_046788423.1 | VWA domain-containing protein | - |
| NML19_RS23115 (NML19_23110) | 45730..45951 | + | 222 | WP_042634307.1 | hypothetical protein | - |
| NML19_RS23120 (NML19_23115) | 46065..47297 | + | 1233 | WP_000220381.1 | toprim domain-containing protein | - |
| NML19_RS23125 (NML19_23120) | 48167..49045 | + | 879 | WP_000762004.1 | hypothetical protein | - |
| NML19_RS23130 (NML19_23125) | 49116..50051 | + | 936 | WP_000691118.1 | hypothetical protein | - |
| NML19_RS23135 (NML19_23130) | 50120..51040 | + | 921 | WP_000991699.1 | hypothetical protein | - |
| NML19_RS23140 (NML19_23135) | 51107..52045 | + | 939 | WP_000472043.1 | hypothetical protein | - |
| NML19_RS23145 (NML19_23140) | 52217..53173 | + | 957 | WP_046788424.1 | hypothetical protein | - |
| NML19_RS23150 (NML19_23145) | 53437..53712 | + | 276 | WP_001004201.1 | hypothetical protein | - |
| NML19_RS23155 (NML19_23150) | 53757..54347 | + | 591 | WP_000578892.1 | hypothetical protein | - |
| NML19_RS23160 (NML19_23155) | 54355..54612 | + | 258 | WP_001371933.1 | hypothetical protein | - |
| NML19_RS23165 (NML19_23160) | 54686..55222 | + | 537 | WP_000107168.1 | hypothetical protein | - |
| NML19_RS23170 (NML19_23165) | 55239..55685 | + | 447 | WP_000549069.1 | hypothetical protein | - |
| NML19_RS23175 (NML19_23170) | 55776..56738 | + | 963 | WP_000119427.1 | DNA replication terminus site-binding protein | - |
| NML19_RS23180 (NML19_23175) | 56748..57653 | + | 906 | WP_001198594.1 | hypothetical protein | - |
| NML19_RS23185 (NML19_23180) | 57589..57933 | + | 345 | WP_001805195.1 | hypothetical protein | - |
| NML19_RS23190 (NML19_23185) | 57955..59130 | - | 1176 | WP_000795947.1 | tyrosine-type recombinase/integrase | - |
| NML19_RS23195 (NML19_23190) | 59301..59513 | + | 213 | WP_001285422.1 | Hha/YmoA family nucleoid-associated regulatory protein | - |
| NML19_RS23200 (NML19_23195) | 59874..60956 | + | 1083 | WP_001232449.1 | hypothetical protein | - |
| NML19_RS23205 (NML19_23200) | 61123..62622 | - | 1500 | WP_001284313.1 | lipopolysaccharide kinase InaA family protein | - |
| NML19_RS23210 (NML19_23205) | 62648..64285 | - | 1638 | WP_000081622.1 | PP2C family serine/threonine-protein phosphatase | - |
| NML19_RS23215 (NML19_23210) | 64285..65325 | - | 1041 | WP_001253653.1 | TerY-C metal binding domain-containing protein | - |
| NML19_RS23220 (NML19_23215) | 65411..66049 | - | 639 | WP_001253658.1 | VWA domain-containing protein | - |
| NML19_RS23225 (NML19_23220) | 66049..66690 | - | 642 | WP_000116681.1 | TerD family protein | - |
| NML19_RS23230 (NML19_23225) | 66713..67351 | - | 639 | WP_001388628.1 | VWA domain-containing protein | - |
| NML19_RS23235 (NML19_23230) | 67814..68281 | - | 468 | WP_001176767.1 | tellurium resistance protein TerW | - |
| NML19_RS23240 (NML19_23235) | 68299..69507 | - | 1209 | WP_000506887.1 | DUF4236 domain-containing protein | - |
| NML19_RS23245 (NML19_23240) | 69518..70474 | - | 957 | WP_000797366.1 | HpcH/HpaI aldolase/citrate lyase family protein | - |
| NML19_RS23250 (NML19_23245) | 70474..71553 | - | 1080 | WP_042634304.1 | cysteine protease StiP family protein | - |
| NML19_RS23255 (NML19_23250) | 71555..72328 | - | 774 | WP_001040059.1 | hypothetical protein | - |
| NML19_RS23260 (NML19_23255) | 72321..73463 | - | 1143 | WP_001285478.1 | phosphoribosyltransferase domain-containing protein | - |
| NML19_RS23265 (NML19_23260) | 73473..74531 | - | 1059 | WP_001035162.1 | ATP-grasp domain-containing protein | - |
| NML19_RS23270 (NML19_23265) | 74855..75436 | + | 582 | WP_042634303.1 | TerD family protein | - |
| NML19_RS23275 (NML19_23270) | 75436..76593 | + | 1158 | WP_001054787.1 | TerD family protein | - |
| NML19_RS23280 (NML19_23275) | 76616..77071 | + | 456 | WP_000007448.1 | tellurite resistance TerB family protein | - |
| NML19_RS23285 (NML19_23280) | 77094..78134 | + | 1041 | WP_000255079.1 | tellurium resistance membrane protein TerC | - |
| NML19_RS23290 (NML19_23285) | 78183..78761 | + | 579 | WP_000116677.1 | tellurium resistance membrane protein TerD | - |
| NML19_RS23295 (NML19_23290) | 78829..79404 | + | 576 | WP_000301242.1 | TerD family protein | - |
| NML19_RS23300 (NML19_23295) | 79833..81074 | + | 1242 | WP_001053338.1 | VWA domain-containing protein | - |
| NML19_RS23305 (NML19_23300) | 81637..81918 | - | 282 | WP_000077926.1 | hypothetical protein | - |
| NML19_RS23310 (NML19_23305) | 81968..82159 | - | 192 | WP_000398480.1 | hypothetical protein | - |
| NML19_RS23315 (NML19_23310) | 82251..82592 | - | 342 | WP_001151575.1 | hypothetical protein | - |
| NML19_RS23320 (NML19_23315) | 82965..83357 | + | 393 | WP_000341066.1 | hypothetical protein | - |
| NML19_RS23325 (NML19_23320) | 83961..84254 | + | 294 | WP_024136327.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| NML19_RS23330 (NML19_23325) | 84259..85584 | + | 1326 | WP_000088046.1 | type II toxin-antitoxin system HipA family toxin | Toxin Detail |
| NML19_RS23335 (NML19_23330) | 85645..85851 | + | 207 | WP_000134171.1 | hypothetical protein | - |
| NML19_RS23340 (NML19_23335) | 85953..86363 | + | 411 | WP_000985911.1 | hypothetical protein | - |
| NML19_RS23345 (NML19_23340) | 86376..87191 | + | 816 | WP_001572439.1 | HNH endonuclease signature motif containing protein | - |
| NML19_RS23350 (NML19_23345) | 87445..87870 | + | 426 | WP_001043843.1 | hypothetical protein | - |
| NML19_RS23355 (NML19_23350) | 88419..88727 | + | 309 | WP_001224687.1 | hypothetical protein | - |
| NML19_RS23360 (NML19_23355) | 88743..89600 | + | 858 | WP_000784387.1 | HNH endonuclease signature motif containing protein | - |
| NML19_RS23365 (NML19_23360) | 89662..89865 | + | 204 | WP_001194555.1 | hypothetical protein | - |
| NML19_RS23370 (NML19_23365) | 90023..93040 | + | 3018 | WP_004199413.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| NML19_RS23375 (NML19_23370) | 93317..94261 | + | 945 | WP_100183899.1 | IS30 family transposase ISAba125 | Transposase |
| NML19_RS23380 (NML19_23375) | 94370..95350 | - | 981 | WP_000019402.1 | IS5 family transposase IS5D | Transposase |
| NML19_RS23385 (NML19_23380) | 95585..96397 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| NML19_RS23390 (NML19_23385) | 96401..96766 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| NML19_RS23395 (NML19_23390) | 96771..97409 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| NML19_RS23400 (NML19_23395) | 97420..97977 | - | 558 | Protein_94 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| NML19_RS23405 (NML19_23400) | 98077..98451 | - | 375 | Protein_95 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| NML19_RS23410 (NML19_23405) | 98456..98590 | - | 135 | WP_023408307.1 | divalent cation tolerance protein CutA | - |
| NML19_RS23415 (NML19_23410) | 98649..98858 | + | 210 | Protein_97 | IS6 family transposase IS15DII | Transposase |
| NML19_RS23420 (NML19_23415) | 99150..99398 | + | 249 | WP_065809026.1 | IS6 family transposase IS15DII | Transposase |
| NML19_RS23425 (NML19_23420) | 99416..99757 | - | 342 | WP_086483225.1 | Multiple antibiotic resistance protein MarA | VF |
| NML19_RS23430 (NML19_23425) | 99788..100144 | - | 357 | Protein_100 | MBL fold metallo-hydrolase | - |
| NML19_RS23435 (NML19_23430) | 100353..101615 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| NML19_RS23440 (NML19_23435) | 101800..101943 | - | 144 | Protein_102 | SMR family transporter | - |
| NML19_RS23445 (NML19_23440) | 102107..102211 | - | 105 | Protein_103 | ANT(3'') family aminoglycoside nucleotidyltransferase | - |
| NML19_RS23450 (NML19_23445) | 102253..102957 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NML19_RS23455 (NML19_23450) | 103452..104036 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| NML19_RS23460 (NML19_23455) | 104036..105274 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| NML19_RS23465 (NML19_23460) | 105271..106176 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| NML19_RS23470 (NML19_23465) | 106298..107002 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NML19_RS23475 (NML19_23470) | 107067..107246 | - | 180 | Protein_109 | helix-turn-helix domain-containing protein | - |
| NML19_RS23480 (NML19_23475) | 107397..108302 | - | 906 | WP_052259183.1 | rRNA adenine N-6-methyltransferase | ARG |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|