MGE detailed information
MGE type: Conjugative plasmid MGE length: 85147 bp
Accession: NZ_CP101225 Location: 1..85147 Organism: Escherichia coli strain EC21Z-144 Replicon: plasmid pEC21Z144-85K
Accession: NZ_CP101225 Location: 1..85147 Organism: Escherichia coli strain EC21Z-144 Replicon: plasmid pEC21Z144-85K
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML25_RS26020 (NML25_26015) | 1..873 | + | 873 | WP_000729438.1 | incFII family plasmid replication initiator RepA | - |
| NML25_RS26025 (NML25_26020) | 1568..1726 | + | 159 | WP_000829588.1 | hypothetical protein | - |
| NML25_RS26030 (NML25_26025) | 1781..2050 | + | 270 | WP_000079932.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| NML25_RS26035 (NML25_26030) | 2050..2328 | + | 279 | WP_013009346.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| NML25_RS26040 (NML25_26035) | 2524..2820 | - | 297 | WP_001419651.1 | hypothetical protein | - |
| NML25_RS26045 (NML25_26040) | 3165..3752 | + | 588 | WP_001418189.1 | serine acetyltransferase | - |
| NML25_RS26050 (NML25_26045) | 4034..4627 | - | 594 | WP_001401779.1 | ProQ/FINO family protein | - |
| NML25_RS26055 (NML25_26050) | 4981..6072 | + | 1092 | Protein_7 | hypothetical protein | - |
| NML25_RS26060 (NML25_26055) | 6103..7716 | - | 1614 | WP_000080193.1 | IS66 family transposase ISEc23 | Transposase |
| NML25_RS26065 (NML25_26060) | 7747..8097 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| NML25_RS26070 (NML25_26065) | 8094..8519 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| NML25_RS26075 (NML25_26070) | 8607..8867 | + | 261 | Protein_11 | hypothetical protein | - |
| NML25_RS26080 (NML25_26075) | 9402..9704 | - | 303 | WP_001245884.1 | hypothetical protein | - |
| NML25_RS26085 (NML25_26080) | 9701..10327 | - | 627 | WP_000587689.1 | ParA family plasmid-partitioning AAA ATPase | - |
| NML25_RS26090 (NML25_26085) | 10523..11794 | - | 1272 | WP_000457510.1 | Y-family DNA polymerase | - |
| NML25_RS26095 (NML25_26090) | 11794..12231 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NML25_RS26100 (NML25_26095) | 12228..12476 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| NML25_RS26105 (NML25_26100) | 12894..13796 | + | 903 | WP_072748701.1 | DUF1281 domain-containing protein | - |
| NML25_RS26110 (NML25_26105) | 13800..14105 | + | 306 | WP_013307862.1 | hypothetical protein | - |
| NML25_RS26115 (NML25_26110) | 14181..14864 | + | 684 | WP_001401756.1 | DNA methylase | - |
| NML25_RS26120 (NML25_26115) | 14865..15086 | + | 222 | WP_001104871.1 | hypothetical protein | - |
| NML25_RS26125 (NML25_26120) | 14980..15534 | + | 555 | WP_077635412.1 | DUF1380 family protein | - |
| NML25_RS26130 (NML25_26125) | 15579..16349 | + | 771 | WP_063117894.1 | hypothetical protein | - |
| NML25_RS26135 (NML25_26130) | 16765..17190 | + | 426 | WP_063080242.1 | antirestriction protein | - |
| NML25_RS26140 (NML25_26135) | 17237..17659 | + | 423 | WP_077466917.1 | DUF1380 family protein | - |
| NML25_RS26145 (NML25_26140) | 17656..17847 | + | 192 | WP_001703906.1 | hypothetical protein | - |
| NML25_RS26150 (NML25_26145) | 18180..18248 | - | 69 | Protein_26 | pilus protein | - |
| NML25_RS26155 (NML25_26150) | 18617..19144 | + | 528 | WP_001276107.1 | single-stranded DNA-binding protein | - |
| NML25_RS26160 (NML25_26155) | 19202..19435 | + | 234 | WP_000006020.1 | DUF905 domain-containing protein | - |
| NML25_RS26165 (NML25_26160) | 19494..21452 | + | 1959 | WP_254841563.1 | ParB/RepB/Spo0J family partition protein | - |
| NML25_RS26170 (NML25_26165) | 21507..21941 | + | 435 | WP_001387500.1 | conjugation system SOS inhibitor PsiB | - |
| NML25_RS26175 (NML25_26170) | 21938..22657 | + | 720 | WP_001276270.1 | plasmid SOS inhibition protein A | - |
| NML25_RS26180 (NML25_26175) | 22654..23250 | + | 597 | Protein_32 | hypothetical protein | - |
| NML25_RS26185 (NML25_26180) | 23712..24212 | + | 501 | WP_000117611.1 | antirestriction protein ArdA | - |
| NML25_RS26190 (NML25_26185) | 24945..25379 | + | 435 | WP_000218862.1 | hypothetical protein | - |
| NML25_RS26195 (NML25_26190) | 25472..25738 | + | 267 | WP_001247860.1 | hypothetical protein | - |
| NML25_RS26200 (NML25_26195) | 25915..26304 | + | 390 | WP_000833767.1 | hypothetical protein | - |
| NML25_RS26205 (NML25_26200) | 26301..27191 | + | 891 | WP_000038343.1 | Recombination-promoting nuclease RpnA | VF |
| NML25_RS26210 (NML25_26205) | 27191..27436 | + | 246 | WP_001260882.1 | hypothetical protein | - |
| NML25_RS26215 (NML25_26210) | 27467..27718 | - | 252 | WP_000148286.1 | helix-turn-helix transcriptional regulator | - |
| NML25_RS26220 (NML25_26215) | 28298..29146 | + | 849 | WP_052984290.1 | DUF4942 domain-containing protein | - |
| NML25_RS26225 (NML25_26220) | 29232..29567 | - | 336 | WP_001401720.1 | hypothetical protein | - |
| NML25_RS26230 (NML25_26225) | 29800..30132 | + | 333 | WP_001291057.1 | plasmid mobilization protein MobA | - |
| NML25_RS26235 (NML25_26230) | 30144..32864 | + | 2721 | WP_000991405.1 | Protein TraI | Relaxase |
| NML25_RS26240 (NML25_26235) | 33085..35385 | - | 2301 | WP_013307869.1 | F-type conjugative transfer protein TrbC | - |
| NML25_RS26245 (NML25_26240) | 35366..36490 | - | 1125 | WP_000152382.1 | DsbC family protein | - |
| NML25_RS26250 (NML25_26245) | 36487..37767 | - | 1281 | WP_001028765.1 | IncI1-type conjugal transfer protein TrbA | - |
| NML25_RS26255 (NML25_26250) | 38444..38695 | + | 252 | WP_001081067.1 | DinQ-like type I toxin DqlB | - |
| NML25_RS26260 (NML25_26255) | 38758..38934 | - | 177 | WP_001054907.1 | hypothetical protein | - |
| NML25_RS26265 (NML25_26260) | 39084..39551 | - | 468 | WP_000598962.1 | thermonuclease family protein | - |
| NML25_RS26270 (NML25_26265) | 39710..40333 | + | 624 | WP_001155247.1 | helix-turn-helix domain-containing protein | - |
| NML25_RS26275 (NML25_26270) | 40531..40746 | - | 216 | WP_000266543.1 | hypothetical protein | - |
| NML25_RS26280 (NML25_26275) | 40750..41118 | - | 369 | WP_125922850.1 | hypothetical protein | - |
| NML25_RS26285 (NML25_26280) | 41130..41321 | - | 192 | WP_000751583.1 | hypothetical protein | - |
| NML25_RS26290 (NML25_26285) | 41409..41651 | - | 243 | WP_000650923.1 | hypothetical protein | - |
| NML25_RS26295 (NML25_26290) | 41981..42133 | + | 153 | WP_001335079.1 | Hok/Gef family protein | - |
| NML25_RS26300 (NML25_26295) | 42271..43857 | - | 1587 | WP_000004564.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| NML25_RS26305 (NML25_26300) | 44131..44778 | - | 648 | WP_087523569.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| NML25_RS26310 (NML25_26305) | 44866..47025 | - | 2160 | WP_000691811.1 | DotA/TraY family protein | - |
| NML25_RS26315 (NML25_26310) | 47100..47669 | - | 570 | WP_000650752.1 | conjugal transfer protein TraX | - |
| NML25_RS26320 (NML25_26315) | 47666..48871 | - | 1206 | WP_001189548.1 | conjugal transfer protein TraW | - |
| NML25_RS26325 (NML25_26320) | 48829..49449 | - | 621 | WP_087523571.1 | conjugal transfer protein TraV | - |
| NML25_RS26330 (NML25_26325) | 49449..52493 | - | 3045 | WP_001024766.1 | conjugal transfer protein | - |
| NML25_RS26335 (NML25_26330) | 52788..53606 | - | 819 | WP_000753550.1 | hypothetical protein | - |
| NML25_RS26340 (NML25_26335) | 53620..53772 | - | 153 | Protein_64 | TraS | - |
| NML25_RS26345 (NML25_26340) | 53829..54227 | - | 399 | WP_000088813.1 | hypothetical protein | - |
| NML25_RS26350 (NML25_26345) | 54274..54804 | - | 531 | WP_000987023.1 | conjugal transfer protein TraQ | - |
| NML25_RS26355 (NML25_26350) | 54801..55514 | - | 714 | WP_087523572.1 | conjugal transfer protein TraP | - |
| NML25_RS26360 (NML25_26355) | 55511..56848 | - | 1338 | WP_013307873.1 | conjugal transfer protein TraO | - |
| NML25_RS26365 (NML25_26360) | 56852..57826 | - | 975 | WP_000547383.1 | hypothetical protein | VF |
| NML25_RS26370 (NML25_26365) | 57837..58532 | - | 696 | WP_001681668.1 | DotI/IcmL family type IV secretion protein | - |
| NML25_RS26375 (NML25_26370) | 58544..58894 | - | 351 | WP_001056367.1 | hypothetical protein | - |
| NML25_RS26380 (NML25_26375) | 58911..62972 | - | 4062 | WP_199358919.1 | DUF5710 domain-containing protein | - |
| NML25_RS26385 (NML25_26380) | 63036..63326 | - | 291 | WP_000817801.1 | IcmT/TraK family protein | - |
| NML25_RS26390 (NML25_26385) | 63323..64471 | - | 1149 | WP_000775210.1 | putative protein YggR | VF |
| NML25_RS26395 (NML25_26390) | 64455..65291 | - | 837 | WP_000745049.1 | hypothetical protein | VF |
| NML25_RS26400 (NML25_26395) | 65288..65746 | - | 459 | WP_001170111.1 | DotD/TraH family lipoprotein | - |
| NML25_RS26405 (NML25_26400) | 65850..67052 | - | 1203 | WP_199358920.1 | conjugal transfer protein TraF | - |
| NML25_RS26410 (NML25_26405) | 67154..67975 | - | 822 | WP_001681675.1 | hypothetical protein | - |
| NML25_RS26415 (NML25_26410) | 68188..69312 | - | 1125 | WP_013307880.1 | site-specific integrase | - |
| NML25_RS26420 (NML25_26415) | 69367..69765 | + | 399 | WP_113367734.1 | phage tail protein | - |
| NML25_RS26425 (NML25_26420) | 69770..70009 | - | 240 | WP_000271302.1 | hypothetical protein | - |
| NML25_RS26430 (NML25_26425) | 70968..72170 | - | 1203 | WP_125133895.1 | hypothetical protein | VF |
| NML25_RS26435 (NML25_26430) | 72188..72814 | - | 627 | WP_049024759.1 | prepilin peptidase | - |
| NML25_RS26440 (NML25_26435) | 72830..73315 | - | 486 | WP_001080767.1 | hypothetical protein | VF |
| NML25_RS26445 (NML25_26440) | 73360..73896 | - | 537 | WP_000111521.1 | hypothetical protein | VF |
| NML25_RS26450 (NML25_26445) | 73958..75052 | - | 1095 | WP_032253914.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| NML25_RS26455 (NML25_26450) | 75054..76562 | - | 1509 | WP_000880806.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| NML25_RS26460 (NML25_26455) | 76666..77124 | - | 459 | WP_000095886.1 | hypothetical protein | VF |
| NML25_RS26465 (NML25_26460) | 77114..78409 | - | 1296 | WP_000129883.1 | type 4b pilus protein PilO2 | - |
| NML25_RS26470 (NML25_26465) | 78430..80049 | - | 1620 | WP_242818306.1 | Outer membrane lipoprotein BfpB | VF |
| NML25_RS26475 (NML25_26470) | 80081..80518 | - | 438 | WP_000539952.1 | hypothetical protein | VF |
| NML25_RS26480 (NML25_26475) | 80522..81592 | - | 1071 | WP_000730430.1 | hypothetical protein | VF |
| NML25_RS26485 (NML25_26480) | 81833..82153 | - | 321 | WP_001447108.1 | hypothetical protein | - |
| NML25_RS26490 (NML25_26485) | 82269..82511 | - | 243 | WP_021515452.1 | PilI type IV pilus biogenesis protein | - |
| NML25_RS26495 (NML25_26490) | 82592..82735 | - | 144 | WP_000176500.1 | hypothetical protein | - |
| NML25_RS26500 (NML25_26495) | 83002..83664 | - | 663 | WP_005082527.1 | hypothetical protein | - |
| NML25_RS26505 (NML25_26500) | 83804..84310 | - | 507 | WP_005082529.1 | transcription termination/antitermination NusG family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|